Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ANE7_LEIMU

TriTrypDb:

LmxM.11.0010

Length:

169

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANE7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANE7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	56	58	PF00675	0.643
CLV_NRD_NRD_1	71	73	PF00675	0.429
CLV_NRD_NRD_1	92	94	PF00675	0.590
CLV_NRD_NRD_1	96	98	PF00675	0.544
CLV_PCSK_KEX2_1	71	73	PF00082	0.673
CLV_PCSK_KEX2_1	96	98	PF00082	0.446
CLV_PCSK_SKI1_1	96	100	PF00082	0.578
DEG_APCC_DBOX_1	95	103	PF00400	0.662
DEG_Nend_UBRbox_2	1	3	PF02207	0.796
DOC_CYCLIN_RxL_1	93	100	PF00134	0.572
DOC_MAPK_gen_1	54	63	PF00069	0.643
DOC_USP7_MATH_1	149	153	PF00917	0.631
DOC_USP7_MATH_1	18	22	PF00917	0.784
DOC_WW_Pin1_4	108	113	PF00397	0.566
LIG_14-3-3_CanoR_1	123	129	PF00244	0.615
LIG_14-3-3_CanoR_1	23	31	PF00244	0.604
LIG_FHA_2	158	164	PF00498	0.371
LIG_LIR_Gen_1	115	122	PF02991	0.671
LIG_LIR_Nem_3	115	121	PF02991	0.675
LIG_PCNA_PIPBox_1	141	150	PF02747	0.638
LIG_PCNA_yPIPBox_3	136	148	PF02747	0.444
LIG_SH2_NCK_1	148	152	PF00017	0.635
LIG_SH2_SRC	148	151	PF00017	0.636
LIG_SH2_STAP1	133	137	PF00017	0.648
LIG_SH3_3	12	18	PF00018	0.515
LIG_SUMO_SIM_anti_2	59	64	PF11976	0.643
LIG_UBA3_1	161	166	PF00899	0.656
MOD_CK1_1	21	27	PF00069	0.668
MOD_CK2_1	157	163	PF00069	0.370
MOD_CK2_1	21	27	PF00069	0.593
MOD_GlcNHglycan	151	154	PF01048	0.614
MOD_GlcNHglycan	19	23	PF01048	0.637
MOD_GlcNHglycan	49	52	PF01048	0.492
MOD_GlcNHglycan	8	11	PF01048	0.748
MOD_N-GLC_1	47	52	PF02516	0.590
MOD_NEK2_1	11	16	PF00069	0.697
MOD_NEK2_1	47	52	PF00069	0.371
MOD_PIKK_1	122	128	PF00454	0.640
MOD_PKA_2	122	128	PF00069	0.640
MOD_PKA_2	88	94	PF00069	0.519
MOD_Plk_1	26	32	PF00069	0.416
MOD_Plk_1	77	83	PF00069	0.662
MOD_Plk_2-3	157	163	PF00069	0.370
MOD_Plk_2-3	77	83	PF00069	0.662
MOD_Plk_4	157	163	PF00069	0.370
MOD_ProDKin_1	108	114	PF00069	0.564
TRG_DiLeu_BaLyEn_6	94	99	PF01217	0.379
TRG_ER_diArg_1	70	72	PF00400	0.671
TRG_ER_diArg_1	96	98	PF00400	0.433
TRG_Pf-PMV_PEXEL_1	33	37	PF00026	0.651
TRG_Pf-PMV_PEXEL_1	54	59	PF00026	0.643
TRG_Pf-PMV_PEXEL_1	85	90	PF00026	0.530
TRG_Pf-PMV_PEXEL_1	96	100	PF00026	0.426

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WRF3	Leishmania donovani	86%	99%
A4HUR3	Leishmania infantum	86%	99%
Q4QH79	Leishmania major	86%	100%