Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ANC8_LEIMU

TriTrypDb:

LmxM.10.1180

Length:

140


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

E9ANC8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANC8


Leishmania	From	To	Domain/Motif	Score
DEG_Nend_Nbox_1	1	3	PF02207	0.432
DEG_SPOP_SBC_1	61	65	PF00917	0.499
DOC_MAPK_MEF2A_6	86	94	PF00069	0.424
DOC_MAPK_NFAT4_5	91	99	PF00069	0.177
DOC_PP1_RVXF_1	89	96	PF00149	0.331
DOC_USP7_MATH_1	61	65	PF00917	0.426
DOC_WW_Pin1_4	113	118	PF00397	0.585
DOC_WW_Pin1_4	52	57	PF00397	0.566
LIG_BRCT_BRCA1_1	32	36	PF00533	0.535
LIG_FHA_1	61	67	PF00498	0.535
LIG_FHA_1	7	13	PF00498	0.321
LIG_FHA_1	79	85	PF00498	0.378
LIG_LIR_Apic_2	116	122	PF02991	0.621
LIG_LIR_Apic_2	27	31	PF02991	0.578
LIG_LIR_Gen_1	33	44	PF02991	0.463
LIG_LIR_Gen_1	9	18	PF02991	0.361
LIG_LIR_Nem_3	33	39	PF02991	0.405
LIG_LIR_Nem_3	85	90	PF02991	0.370
LIG_LIR_Nem_3	9	13	PF02991	0.358
LIG_SH2_CRK	49	53	PF00017	0.355
LIG_SH2_STAT5	28	31	PF00017	0.582
LIG_SH3_3	111	117	PF00018	0.469
LIG_SH3_3	53	59	PF00018	0.493
LIG_TYR_ITIM	47	52	PF00017	0.324
MOD_GlcNHglycan	32	35	PF01048	0.316
MOD_GSK3_1	109	116	PF00069	0.468
MOD_N-GLC_1	61	66	PF02516	0.739
MOD_NEK2_1	24	29	PF00069	0.501
MOD_Plk_1	61	67	PF00069	0.482
MOD_Plk_4	134	140	PF00069	0.611
MOD_Plk_4	24	30	PF00069	0.501
MOD_Plk_4	62	68	PF00069	0.476
MOD_ProDKin_1	113	119	PF00069	0.594
MOD_ProDKin_1	52	58	PF00069	0.569
TRG_ENDOCYTIC_2	49	52	PF00928	0.369


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I727	Leptomonas seymouri	63%	99%
A0A0S4IN42	Bodo saltans	40%	100%
A0A1X0NQE7	Trypanosomatidae	47%	100%
A0A3S7WRD7	Leishmania donovani	90%	100%
A0A422NBW5	Trypanosoma rangeli	50%	100%
A4H6A6	Leishmania braziliensis	66%	100%
A4HUN0	Leishmania infantum	90%	100%
C9ZVR4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	99%
Q4QH96	Leishmania major	90%	100%