LeishMANIAdb
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Multiple RNA-binding domain-containing protein 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Multiple RNA-binding domain-containing protein 1
Gene product:
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain), putative
Species:
Leishmania mexicana
UniProt:
E9AN80_LEIMU
TriTrypDb:
LmxM.10.0700
Length:
819

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005634 nucleus 5 1
GO:0005654 nucleoplasm 2 1
GO:0005730 nucleolus 5 1
GO:0005737 cytoplasm 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
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Expansion

Sequence features

E9AN80
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AN80

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0003676 nucleic acid binding 3 12
GO:0003723 RNA binding 4 12
GO:0003729 mRNA binding 5 1
GO:0005488 binding 1 12
GO:0097159 organic cyclic compound binding 2 12
GO:1901363 heterocyclic compound binding 2 12
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 169 173 PF00656 0.716
CLV_C14_Caspase3-7 188 192 PF00656 0.584
CLV_C14_Caspase3-7 460 464 PF00656 0.446
CLV_C14_Caspase3-7 558 562 PF00656 0.618
CLV_C14_Caspase3-7 56 60 PF00656 0.662
CLV_MEL_PAP_1 470 476 PF00089 0.401
CLV_NRD_NRD_1 115 117 PF00675 0.674
CLV_NRD_NRD_1 123 125 PF00675 0.664
CLV_NRD_NRD_1 178 180 PF00675 0.671
CLV_NRD_NRD_1 3 5 PF00675 0.660
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HY42 Leptomonas seymouri 67% 87%
A0A0S4J8G6 Bodo saltans 42% 91%
A0A1X0NQT4 Trypanosomatidae 50% 94%
A0A3Q8I7R0 Leishmania donovani 91% 86%
A0A3R7NQE9 Trypanosoma rangeli 50% 96%
A4H661 Leishmania braziliensis 79% 100%
A4HUI2 Leishmania infantum 91% 86%
C9ZVK7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 50% 96%
P0CR16 Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) 29% 100%
P0CR17 Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) 29% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS