LeishMANIAdb
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Zf-met2 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Zf-met2 domain-containing protein
Gene product:
4F5 protein family/Zinc-binding, putative
Species:
Leishmania mexicana
UniProt:
E9AN52_LEIMU
TriTrypDb:
LmxM.10.0450
Length:
83

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
Term Name Level Count
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9AN52
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AN52

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 12 14 PF00675 0.271
CLV_NRD_NRD_1 56 58 PF00675 0.318
CLV_PCSK_KEX2_1 12 14 PF00082 0.271
CLV_PCSK_KEX2_1 56 58 PF00082 0.318
CLV_PCSK_PC7_1 8 14 PF00082 0.296
CLV_PCSK_SKI1_1 15 19 PF00082 0.336
LIG_FHA_2 26 32 PF00498 0.472
LIG_LIR_Nem_3 75 81 PF02991 0.333
LIG_Pex14_2 74 78 PF04695 0.350
LIG_SH3_3 52 58 PF00018 0.432
MOD_GlcNHglycan 2 5 PF01048 0.314
MOD_GlcNHglycan 21 24 PF01048 0.271
MOD_N-GLC_2 5 7 PF02516 0.271
MOD_SUMO_rev_2 14 20 PF00179 0.527
TRG_ER_diArg_1 55 57 PF00400 0.319

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HR95 Leptomonas seymouri 84% 100%
A0A0S4JSJ0 Bodo saltans 60% 79%
A0A1X0NRV9 Trypanosomatidae 68% 78%
A0A3S7WR26 Leishmania donovani 95% 100%
A4H625 Leishmania braziliensis 84% 100%
A4HUF3 Leishmania infantum 95% 100%
Q4QHH3 Leishmania major 92% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS