MORN repeat-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AN27_LEIMU

TriTrypDb:

LmxM.10.0195

Length:

221

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

E9AN27

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AN27

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	36	38	PF00675	0.454
CLV_PCSK_KEX2_1	36	38	PF00082	0.454
CLV_PCSK_SKI1_1	6	10	PF00082	0.700
DEG_SPOP_SBC_1	81	85	PF00917	0.672
DOC_ANK_TNKS_1	161	168	PF00023	0.440
DOC_ANK_TNKS_1	36	43	PF00023	0.520
DOC_CDC14_PxL_1	190	198	PF14671	0.593
DOC_MAPK_gen_1	4	16	PF00069	0.591
DOC_MAPK_MEF2A_6	198	206	PF00069	0.415
DOC_USP7_MATH_1	54	58	PF00917	0.723

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I749	Leptomonas seymouri	59%	86%
A0A0S4J1U4	Bodo saltans	32%	100%
A0A1X0NQ66	Trypanosomatidae	44%	100%
A0A3R7KKB6	Trypanosoma rangeli	47%	100%
A0A3S5H6F3	Leishmania donovani	87%	100%
A0A422NAN4	Trypanosoma rangeli	35%	100%
A4HUC7	Leishmania infantum	86%	100%
C9ZJK1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
C9ZKJ2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	69%
C9ZVG4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%

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