LeishMANIAdb
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Reverse transcriptase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Reverse transcriptase domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AN03_LEIMU
TriTrypDb:
LmxM.09.1505
Length:
121

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AN03
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AN03

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 14 16 PF00675 0.468
CLV_NRD_NRD_1 35 37 PF00675 0.531
CLV_NRD_NRD_1 46 48 PF00675 0.454
CLV_NRD_NRD_1 5 7 PF00675 0.545
CLV_PCSK_FUR_1 12 16 PF00082 0.485
CLV_PCSK_KEX2_1 14 16 PF00082 0.468
CLV_PCSK_KEX2_1 45 47 PF00082 0.532
CLV_PCSK_KEX2_1 5 7 PF00082 0.545
CLV_PCSK_PC1ET2_1 45 47 PF00082 0.585
CLV_PCSK_PC7_1 42 48 PF00082 0.472
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I1L1 Leptomonas seymouri 83% 100%
A0A0S4JCT2 Bodo saltans 52% 95%
A0A1X0NHV8 Trypanosomatidae 53% 94%
A0A3S5ISF1 Trypanosoma rangeli 57% 99%
A0A3S7WQX5 Leishmania donovani 97% 100%
A4H5X7 Leishmania braziliensis 91% 100%
A4HU73 Leishmania infantum 97% 100%
D0A9Q5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 57% 90%
Q4QHM5 Leishmania major 95% 100%
V5BI65 Trypanosoma cruzi 61% 99%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS