Rhodanese domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

rhodanese-like domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9AMZ8_LEIMU

TriTrypDb:

LmxM.09.1460

Length:

150

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 16
NetGPI	no	yes: 0, no: 16

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMZ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMZ8

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	6
GO:0004792	thiosulfate sulfurtransferase activity	5	6
GO:0016740	transferase activity	2	6
GO:0016782	transferase activity, transferring sulphur-containing groups	3	6
GO:0016783	sulfurtransferase activity	4	6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	19	23	PF00082	0.286
CLV_PCSK_SKI1_1	63	67	PF00082	0.291
DEG_Nend_Nbox_1	1	3	PF02207	0.469
DOC_CKS1_1	132	137	PF01111	0.592
DOC_CKS1_1	145	150	PF01111	0.557
DOC_PP4_FxxP_1	81	84	PF00568	0.368
DOC_USP7_MATH_1	135	139	PF00917	0.626
DOC_USP7_MATH_1	23	27	PF00917	0.320
DOC_WW_Pin1_4	131	136	PF00397	0.559
DOC_WW_Pin1_4	144	149	PF00397	0.572
DOC_WW_Pin1_4	64	69	PF00397	0.524
LIG_14-3-3_CanoR_1	3	7	PF00244	0.553
LIG_Actin_WH2_2	48	65	PF00022	0.467
LIG_FHA_1	3	9	PF00498	0.502
LIG_FHA_1	40	46	PF00498	0.407
LIG_FHA_1	89	95	PF00498	0.464
LIG_GBD_Chelix_1	105	113	PF00786	0.257
LIG_LIR_Apic_2	78	84	PF02991	0.385
LIG_LIR_Gen_1	74	84	PF02991	0.511
LIG_LIR_Nem_3	126	132	PF02991	0.443
LIG_LIR_Nem_3	74	80	PF02991	0.504
LIG_Pex14_1	125	129	PF04695	0.433
LIG_Pex14_2	121	125	PF04695	0.426
LIG_Pex14_2	77	81	PF04695	0.401
LIG_SH2_CRK	132	136	PF00017	0.599
LIG_SH2_STAT5	11	14	PF00017	0.337
LIG_SH2_STAT5	96	99	PF00017	0.419
LIG_SH3_3	54	60	PF00018	0.420
LIG_SH3_3	62	68	PF00018	0.424
LIG_SUMO_SIM_par_1	35	42	PF11976	0.461
MOD_CDK_SPxK_1	144	150	PF00069	0.454
MOD_CK1_1	144	150	PF00069	0.577
MOD_CK1_1	67	73	PF00069	0.544
MOD_CK2_1	38	44	PF00069	0.436
MOD_CK2_1	67	73	PF00069	0.448
MOD_CMANNOS	125	128	PF00535	0.249
MOD_GlcNHglycan	102	105	PF01048	0.286
MOD_GlcNHglycan	121	124	PF01048	0.201
MOD_GlcNHglycan	137	140	PF01048	0.528
MOD_GlcNHglycan	25	28	PF01048	0.446
MOD_GlcNHglycan	52	55	PF01048	0.254
MOD_GSK3_1	119	126	PF00069	0.502
MOD_GSK3_1	131	138	PF00069	0.604
MOD_N-GLC_1	119	124	PF02516	0.241
MOD_NEK2_1	121	126	PF00069	0.462
MOD_NEK2_1	2	7	PF00069	0.450
MOD_PIKK_1	123	129	PF00454	0.541
MOD_PIKK_1	88	94	PF00454	0.426
MOD_PK_1	10	16	PF00069	0.232
MOD_PKA_2	2	8	PF00069	0.479
MOD_PKA_2	39	45	PF00069	0.409
MOD_Plk_4	67	73	PF00069	0.483
MOD_ProDKin_1	131	137	PF00069	0.570
MOD_ProDKin_1	144	150	PF00069	0.573
MOD_ProDKin_1	64	70	PF00069	0.524
TRG_ENDOCYTIC_2	11	14	PF00928	0.358
TRG_Pf-PMV_PEXEL_1	10	15	PF00026	0.233

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8M5	Leptomonas seymouri	34%	100%
A0A0N1PG29	Leptomonas seymouri	64%	100%
A0A1X0NHS7	Trypanosomatidae	38%	100%
A0A1X0NIC3	Trypanosomatidae	34%	100%
A0A1X0NJI4	Trypanosomatidae	30%	100%
A0A1X0NJQ7	Trypanosomatidae	52%	100%
A0A3R7LB88	Trypanosoma rangeli	33%	100%
A0A3R7MT99	Trypanosoma rangeli	28%	100%
A0A3R7P0U7	Trypanosoma rangeli	49%	100%
A0A3S7WQW6	Leishmania donovani	89%	100%
A0A3S7WQX1	Leishmania donovani	33%	100%
A4H5X3	Leishmania braziliensis	85%	100%
A4H5X4	Leishmania braziliensis	35%	100%
A4HU68	Leishmania infantum	89%	100%
A4HU69	Leishmania infantum	33%	100%
D0A9Q0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
E9AMZ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
P22978	Drosophila melanogaster	34%	100%
Q4QHM8	Leishmania major	33%	100%
Q4QHM9	Leishmania major	89%	100%
V5BI16	Trypanosoma cruzi	31%	93%
V5BMN5	Trypanosoma cruzi	47%	100%
V5BMN9	Trypanosoma cruzi	34%	100%