Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AMY9_LEIMU

TriTrypDb:

LmxM.09.1370

Length:

268

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMY9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMY9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	235	239	PF00656	0.728
CLV_NRD_NRD_1	103	105	PF00675	0.413
CLV_NRD_NRD_1	201	203	PF00675	0.613
CLV_NRD_NRD_1	248	250	PF00675	0.745
CLV_NRD_NRD_1	263	265	PF00675	0.514
CLV_PCSK_KEX2_1	102	104	PF00082	0.473
CLV_PCSK_KEX2_1	201	203	PF00082	0.613
CLV_PCSK_KEX2_1	229	231	PF00082	0.704
CLV_PCSK_KEX2_1	248	250	PF00082	0.642
CLV_PCSK_PC1ET2_1	102	104	PF00082	0.489
CLV_PCSK_PC1ET2_1	229	231	PF00082	0.591
CLV_PCSK_PC7_1	225	231	PF00082	0.584
CLV_PCSK_PC7_1	244	250	PF00082	0.643
CLV_PCSK_PC7_1	99	105	PF00082	0.324
CLV_PCSK_SKI1_1	111	115	PF00082	0.479
CLV_PCSK_SKI1_1	121	125	PF00082	0.381
DEG_APCC_DBOX_1	214	222	PF00400	0.588
DOC_CKS1_1	240	245	PF01111	0.521
DOC_PP2B_LxvP_1	40	43	PF13499	0.695
DOC_USP7_MATH_1	126	130	PF00917	0.602
DOC_USP7_MATH_1	139	143	PF00917	0.416
DOC_WW_Pin1_4	175	180	PF00397	0.685
DOC_WW_Pin1_4	184	189	PF00397	0.621
DOC_WW_Pin1_4	192	197	PF00397	0.541
DOC_WW_Pin1_4	239	244	PF00397	0.639
DOC_WW_Pin1_4	253	258	PF00397	0.642
DOC_WW_Pin1_4	8	13	PF00397	0.717
LIG_14-3-3_CanoR_1	104	113	PF00244	0.402
LIG_14-3-3_CanoR_1	138	144	PF00244	0.493
LIG_14-3-3_CanoR_1	14	22	PF00244	0.527
LIG_14-3-3_CanoR_1	215	219	PF00244	0.704
LIG_14-3-3_CanoR_1	230	235	PF00244	0.511
LIG_14-3-3_CanoR_1	248	257	PF00244	0.632
LIG_Actin_WH2_2	217	234	PF00022	0.584
LIG_BIR_III_4	17	21	PF00653	0.598
LIG_Clathr_ClatBox_1	112	116	PF01394	0.544
LIG_FHA_2	112	118	PF00498	0.484
LIG_LIR_Apic_2	191	196	PF02991	0.720
LIG_SH2_CRK	193	197	PF00017	0.721
LIG_SUMO_SIM_par_1	111	118	PF11976	0.610
LIG_TRAF2_1	114	117	PF00917	0.544
LIG_TRAF2_1	217	220	PF00917	0.578
MOD_CDC14_SPxK_1	11	14	PF00782	0.603
MOD_CDK_SPK_2	175	180	PF00069	0.598
MOD_CDK_SPK_2	239	244	PF00069	0.616
MOD_CDK_SPxK_1	184	190	PF00069	0.598
MOD_CDK_SPxK_1	8	14	PF00069	0.600
MOD_CDK_SPxxK_3	192	199	PF00069	0.618
MOD_CK1_1	233	239	PF00069	0.619
MOD_CK1_1	253	259	PF00069	0.478
MOD_CK1_1	54	60	PF00069	0.574
MOD_CK2_1	111	117	PF00069	0.519
MOD_CK2_1	214	220	PF00069	0.590
MOD_GlcNHglycan	116	120	PF01048	0.586
MOD_GlcNHglycan	203	206	PF01048	0.595
MOD_GlcNHglycan	60	63	PF01048	0.601
MOD_GlcNHglycan	64	67	PF01048	0.518
MOD_GSK3_1	111	118	PF00069	0.486
MOD_GSK3_1	210	217	PF00069	0.635
MOD_GSK3_1	230	237	PF00069	0.462
MOD_GSK3_1	249	256	PF00069	0.633
MOD_GSK3_1	54	61	PF00069	0.634
MOD_NEK2_1	115	120	PF00069	0.415
MOD_NEK2_1	98	103	PF00069	0.460
MOD_PIKK_1	105	111	PF00454	0.438
MOD_PIKK_1	210	216	PF00454	0.713
MOD_PIKK_1	250	256	PF00454	0.734
MOD_PK_1	230	236	PF00069	0.608
MOD_PKA_1	201	207	PF00069	0.687
MOD_PKA_1	248	254	PF00069	0.739
MOD_PKA_2	13	19	PF00069	0.606
MOD_PKA_2	201	207	PF00069	0.747
MOD_PKA_2	214	220	PF00069	0.590
MOD_PKA_2	224	230	PF00069	0.580
MOD_PKA_2	247	253	PF00069	0.640
MOD_PKA_2	98	104	PF00069	0.385
MOD_Plk_1	51	57	PF00069	0.509
MOD_Plk_4	51	57	PF00069	0.567
MOD_ProDKin_1	175	181	PF00069	0.693
MOD_ProDKin_1	184	190	PF00069	0.621
MOD_ProDKin_1	192	198	PF00069	0.542
MOD_ProDKin_1	239	245	PF00069	0.639
MOD_ProDKin_1	253	259	PF00069	0.638
MOD_ProDKin_1	8	14	PF00069	0.720
TRG_DiLeu_BaLyEn_6	35	40	PF01217	0.672
TRG_ER_diArg_1	103	105	PF00400	0.413
TRG_NLS_MonoExtN_4	99	106	PF00514	0.321
TRG_Pf-PMV_PEXEL_1	82	87	PF00026	0.437

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8A2	Leptomonas seymouri	47%	97%
A0A3S5H6E8	Leishmania donovani	87%	100%
A4H5W4	Leishmania braziliensis	69%	100%
A4HU59	Leishmania infantum	88%	100%
Q4QHN8	Leishmania major	88%	100%