LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9AMY8_LEIMU
TriTrypDb:
LmxM.09.1360
Length:
125

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMY8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMY8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 24 26 PF00675 0.720
CLV_NRD_NRD_1 83 85 PF00675 0.737
CLV_PCSK_FUR_1 22 26 PF00082 0.776
CLV_PCSK_KEX2_1 21 23 PF00082 0.760
CLV_PCSK_KEX2_1 24 26 PF00082 0.707
CLV_PCSK_PC1ET2_1 21 23 PF00082 0.782
CLV_PCSK_SKI1_1 37 41 PF00082 0.578
DOC_CYCLIN_RxL_1 34 43 PF00134 0.576
DOC_CYCLIN_yCln2_LP_2 106 112 PF00134 0.649
DOC_PP4_FxxP_1 113 116 PF00568 0.679
DOC_WW_Pin1_4 45 50 PF00397 0.544
LIG_14-3-3_CanoR_1 41 49 PF00244 0.747
LIG_14-3-3_CterR_2 120 125 PF00244 0.514
LIG_BIR_II_1 1 5 PF00653 0.550
LIG_FHA_2 92 98 PF00498 0.551
LIG_MYND_1 55 59 PF01753 0.766
LIG_SH2_STAP1 71 75 PF00017 0.532
LIG_SH3_3 93 99 PF00018 0.545
LIG_TRFH_1 113 117 PF08558 0.478
MOD_CDK_SPxxK_3 45 52 PF00069 0.541
MOD_CK1_1 3 9 PF00069 0.641
MOD_CK1_1 63 69 PF00069 0.551
MOD_CK2_1 12 18 PF00069 0.762
MOD_Cter_Amidation 19 22 PF01082 0.784
MOD_GlcNHglycan 45 48 PF01048 0.533
MOD_GlcNHglycan 60 63 PF01048 0.763
MOD_GSK3_1 26 33 PF00069 0.595
MOD_GSK3_1 76 83 PF00069 0.768
MOD_NEK2_1 40 45 PF00069 0.521
MOD_PIKK_1 30 36 PF00454 0.711
MOD_PKA_2 40 46 PF00069 0.519
MOD_PKA_2 76 82 PF00069 0.657
MOD_PKB_1 56 64 PF00069 0.547
MOD_ProDKin_1 45 51 PF00069 0.548
MOD_SUMO_for_1 13 16 PF00179 0.567
MOD_SUMO_rev_2 15 23 PF00179 0.763
TRG_ENDOCYTIC_2 110 113 PF00928 0.703
TRG_ER_diArg_1 22 25 PF00400 0.729
TRG_ER_diArg_1 55 58 PF00400 0.548
TRG_NLS_MonoCore_2 83 88 PF00514 0.742
TRG_NLS_MonoExtC_3 20 25 PF00514 0.778
TRG_NLS_MonoExtN_4 82 88 PF00514 0.740

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WQV5 Leishmania donovani 58% 98%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS