Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AMY3_LEIMU

TriTrypDb:

LmxM.09.1315

Length:

350

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMY3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMY3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	305	309	PF00656	0.737
CLV_NRD_NRD_1	111	113	PF00675	0.556
CLV_NRD_NRD_1	286	288	PF00675	0.726
CLV_NRD_NRD_1	334	336	PF00675	0.735
CLV_PCSK_KEX2_1	111	113	PF00082	0.556
CLV_PCSK_KEX2_1	285	287	PF00082	0.721
CLV_PCSK_KEX2_1	334	336	PF00082	0.735
DEG_APCC_DBOX_1	93	101	PF00400	0.583
DEG_MDM2_SWIB_1	54	62	PF02201	0.504
DEG_Nend_UBRbox_1	1	4	PF02207	0.569
DEG_SPOP_SBC_1	177	181	PF00917	0.687
DEG_SPOP_SBC_1	277	281	PF00917	0.521
DOC_MAPK_gen_1	334	342	PF00069	0.700
DOC_USP7_MATH_1	13	17	PF00917	0.697
DOC_USP7_MATH_1	177	181	PF00917	0.719
DOC_USP7_MATH_1	266	270	PF00917	0.762
DOC_USP7_MATH_1	277	281	PF00917	0.644
DOC_USP7_MATH_1	294	298	PF00917	0.795
DOC_USP7_MATH_1	309	313	PF00917	0.659
DOC_USP7_MATH_1	318	322	PF00917	0.631
DOC_WW_Pin1_4	192	197	PF00397	0.729
DOC_WW_Pin1_4	20	25	PF00397	0.594
DOC_WW_Pin1_4	207	212	PF00397	0.558
DOC_WW_Pin1_4	26	31	PF00397	0.646
DOC_WW_Pin1_4	34	39	PF00397	0.663
LIG_14-3-3_CanoR_1	2	6	PF00244	0.545
LIG_14-3-3_CanoR_1	255	263	PF00244	0.615
LIG_14-3-3_CanoR_1	275	283	PF00244	0.558
LIG_14-3-3_CanoR_1	310	318	PF00244	0.544
LIG_BIR_III_4	308	312	PF00653	0.752
LIG_BRCT_BRCA1_1	174	178	PF00533	0.485
LIG_BRCT_BRCA1_1	50	54	PF00533	0.274
LIG_EVH1_1	21	25	PF00568	0.472
LIG_FHA_1	179	185	PF00498	0.696
LIG_FHA_1	255	261	PF00498	0.789
LIG_FHA_1	294	300	PF00498	0.716
LIG_FHA_2	193	199	PF00498	0.772
LIG_FHA_2	43	49	PF00498	0.508
LIG_LIR_Gen_1	136	146	PF02991	0.767
LIG_LIR_Gen_1	198	208	PF02991	0.676
LIG_LIR_Nem_3	136	141	PF02991	0.696
LIG_LIR_Nem_3	198	203	PF02991	0.678
LIG_LIR_Nem_3	244	249	PF02991	0.553
LIG_LIR_Nem_3	269	274	PF02991	0.798
LIG_LIR_Nem_3	51	57	PF02991	0.318
LIG_MYND_1	272	276	PF01753	0.809
LIG_PDZ_Class_3	345	350	PF00595	0.768
LIG_Pex14_2	54	58	PF04695	0.493
LIG_SH2_STAT5	68	71	PF00017	0.481
LIG_SH3_3	102	108	PF00018	0.620
LIG_SH3_3	16	22	PF00018	0.768
LIG_SUMO_SIM_anti_2	16	23	PF11976	0.767
LIG_SUMO_SIM_anti_2	296	303	PF11976	0.812
LIG_SUMO_SIM_anti_2	339	349	PF11976	0.690
LIG_SUMO_SIM_par_1	16	23	PF11976	0.767
LIG_SUMO_SIM_par_1	296	303	PF11976	0.719
LIG_SUMO_SIM_par_1	339	349	PF11976	0.682
MOD_CDK_SPxK_1	34	40	PF00069	0.676
MOD_CDK_SPxxK_3	207	214	PF00069	0.727
MOD_CK1_1	172	178	PF00069	0.531
MOD_CK1_1	179	185	PF00069	0.715
MOD_CK1_1	218	224	PF00069	0.721
MOD_CK2_1	134	140	PF00069	0.745
MOD_CK2_1	192	198	PF00069	0.730
MOD_CK2_1	207	213	PF00069	0.520
MOD_CK2_1	89	95	PF00069	0.751
MOD_Cter_Amidation	283	286	PF01082	0.741
MOD_GlcNHglycan	222	226	PF01048	0.687
MOD_GlcNHglycan	268	271	PF01048	0.672
MOD_GlcNHglycan	296	299	PF01048	0.746
MOD_GlcNHglycan	313	316	PF01048	0.696
MOD_GlcNHglycan	320	323	PF01048	0.707
MOD_GSK3_1	136	143	PF00069	0.636
MOD_GSK3_1	169	176	PF00069	0.659
MOD_GSK3_1	180	187	PF00069	0.685
MOD_GSK3_1	214	221	PF00069	0.712
MOD_GSK3_1	241	248	PF00069	0.550
MOD_GSK3_1	89	96	PF00069	0.678
MOD_NEK2_1	1	6	PF00069	0.614
MOD_NEK2_1	178	183	PF00069	0.629
MOD_NEK2_1	73	78	PF00069	0.516
MOD_NEK2_2	42	47	PF00069	0.564
MOD_PKA_2	1	7	PF00069	0.548
MOD_PKA_2	254	260	PF00069	0.712
MOD_PKA_2	309	315	PF00069	0.836
MOD_PKA_2	327	333	PF00069	0.825
MOD_PKA_2	93	99	PF00069	0.598
MOD_Plk_1	73	79	PF00069	0.629
MOD_Plk_4	184	190	PF00069	0.565
MOD_Plk_4	74	80	PF00069	0.363
MOD_ProDKin_1	192	198	PF00069	0.730
MOD_ProDKin_1	20	26	PF00069	0.592
MOD_ProDKin_1	207	213	PF00069	0.563
MOD_ProDKin_1	34	40	PF00069	0.665
TRG_ER_diArg_1	285	287	PF00400	0.696

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4T4	Leptomonas seymouri	30%	95%
A0A3S7WQV7	Leishmania donovani	84%	100%
A4H5V9	Leishmania braziliensis	66%	100%
E9ACQ8	Leishmania major	86%	100%
E9AG96	Leishmania infantum	86%	100%