Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AMV5_LEIMU

TriTrypDb:

LmxM.09.1030

Length:

306

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMV5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMV5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	86	90	PF00656	0.594
CLV_C14_Caspase3-7	95	99	PF00656	0.457
CLV_NRD_NRD_1	116	118	PF00675	0.545
CLV_NRD_NRD_1	171	173	PF00675	0.724
CLV_NRD_NRD_1	195	197	PF00675	0.530
CLV_NRD_NRD_1	216	218	PF00675	0.600
CLV_NRD_NRD_1	36	38	PF00675	0.702
CLV_PCSK_FUR_1	214	218	PF00082	0.589
CLV_PCSK_FUR_1	34	38	PF00082	0.658
CLV_PCSK_KEX2_1	116	118	PF00082	0.545
CLV_PCSK_KEX2_1	194	196	PF00082	0.542
CLV_PCSK_KEX2_1	204	206	PF00082	0.433
CLV_PCSK_KEX2_1	216	218	PF00082	0.600
CLV_PCSK_KEX2_1	36	38	PF00082	0.659
CLV_PCSK_PC1ET2_1	204	206	PF00082	0.487
CLV_PCSK_SKI1_1	116	120	PF00082	0.629
CLV_PCSK_SKI1_1	247	251	PF00082	0.426
CLV_PCSK_SKI1_1	28	32	PF00082	0.594
DEG_COP1_1	157	165	PF00400	0.629
DEG_SPOP_SBC_1	18	22	PF00917	0.645
DEG_SPOP_SBC_1	82	86	PF00917	0.585
DOC_CYCLIN_yCln2_LP_2	215	221	PF00134	0.549
DOC_CYCLIN_yCln2_LP_2	52	58	PF00134	0.606
DOC_MAPK_gen_1	204	210	PF00069	0.525
DOC_PP4_FxxP_1	44	47	PF00568	0.624
DOC_USP7_MATH_1	12	16	PF00917	0.702
DOC_USP7_MATH_1	165	169	PF00917	0.632
DOC_USP7_MATH_1	29	33	PF00917	0.538
DOC_USP7_MATH_1	292	296	PF00917	0.591
DOC_USP7_MATH_1	66	70	PF00917	0.520
DOC_USP7_MATH_1	82	86	PF00917	0.585
DOC_WW_Pin1_4	10	15	PF00397	0.629
DOC_WW_Pin1_4	167	172	PF00397	0.650
DOC_WW_Pin1_4	43	48	PF00397	0.805
LIG_14-3-3_CanoR_1	16	25	PF00244	0.649
LIG_14-3-3_CanoR_1	205	211	PF00244	0.497
LIG_14-3-3_CanoR_1	272	279	PF00244	0.488
LIG_14-3-3_CanoR_1	36	44	PF00244	0.578
LIG_BRCT_BRCA1_1	233	237	PF00533	0.542
LIG_BRCT_BRCA1_1	71	75	PF00533	0.526
LIG_IBAR_NPY_1	54	56	PF08397	0.637
LIG_LIR_Apic_2	41	47	PF02991	0.618
LIG_SH2_STAP1	102	106	PF00017	0.524
LIG_SH3_3	141	147	PF00018	0.646
LIG_SH3_3	159	165	PF00018	0.688
LIG_SH3_3	4	10	PF00018	0.759
MOD_CDC14_SPxK_1	13	16	PF00782	0.637
MOD_CDC14_SPxK_1	170	173	PF00782	0.595
MOD_CDK_SPK_2	167	172	PF00069	0.650
MOD_CDK_SPxK_1	10	16	PF00069	0.634
MOD_CDK_SPxK_1	167	173	PF00069	0.608
MOD_CK1_1	228	234	PF00069	0.559
MOD_CK1_1	295	301	PF00069	0.661
MOD_CK1_1	69	75	PF00069	0.525
MOD_GlcNHglycan	103	107	PF01048	0.364
MOD_GlcNHglycan	226	231	PF01048	0.597
MOD_GlcNHglycan	233	236	PF01048	0.490
MOD_GlcNHglycan	294	297	PF01048	0.651
MOD_GlcNHglycan	298	301	PF01048	0.633
MOD_GlcNHglycan	31	34	PF01048	0.639
MOD_GlcNHglycan	68	71	PF01048	0.524
MOD_GSK3_1	243	250	PF00069	0.601
MOD_GSK3_1	292	299	PF00069	0.646
MOD_N-GLC_1	292	297	PF02516	0.640
MOD_NMyristoyl	1	7	PF02799	0.535
MOD_PIKK_1	92	98	PF00454	0.446
MOD_PKA_2	271	277	PF00069	0.482
MOD_Plk_2-3	240	246	PF00069	0.408
MOD_Plk_4	3	9	PF00069	0.595
MOD_ProDKin_1	10	16	PF00069	0.634
MOD_ProDKin_1	167	173	PF00069	0.644
MOD_ProDKin_1	43	49	PF00069	0.804
MOD_SUMO_for_1	121	124	PF00179	0.390
MOD_SUMO_rev_2	157	163	PF00179	0.534
TRG_DiLeu_BaEn_1	59	64	PF01217	0.629
TRG_ENDOCYTIC_2	197	200	PF00928	0.593
TRG_ER_diArg_1	108	111	PF00400	0.531
TRG_ER_diArg_1	193	196	PF00400	0.531
TRG_ER_diArg_1	214	217	PF00400	0.581
TRG_ER_diArg_1	60	63	PF00400	0.630
TRG_Pf-PMV_PEXEL_1	181	185	PF00026	0.505

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WQV2	Leishmania donovani	82%	98%
A4H5T2	Leishmania braziliensis	62%	100%
A4HU25	Leishmania infantum	82%	98%
Q4QHS1	Leishmania major	80%	98%