Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AMV0_LEIMU

TriTrypDb:

LmxM.09.0980

Length:

1006

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMV0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMV0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	175	179	PF00656	0.594
CLV_C14_Caspase3-7	283	287	PF00656	0.496
CLV_C14_Caspase3-7	411	415	PF00656	0.455
CLV_C14_Caspase3-7	986	990	PF00656	0.541
CLV_NRD_NRD_1	194	196	PF00675	0.619
CLV_NRD_NRD_1	240	242	PF00675	0.552
CLV_NRD_NRD_1	424	426	PF00675	0.448
CLV_NRD_NRD_1	581	583	PF00675	0.640
CLV_NRD_NRD_1	6	8	PF00675	0.502
CLV_PCSK_FUR_1	238	242	PF00082	0.546
CLV_PCSK_KEX2_1	105	107	PF00082	0.648
CLV_PCSK_KEX2_1	196	198	PF00082	0.622
CLV_PCSK_KEX2_1	207	209	PF00082	0.629
CLV_PCSK_KEX2_1	240	242	PF00082	0.552
CLV_PCSK_KEX2_1	423	425	PF00082	0.447
CLV_PCSK_KEX2_1	580	582	PF00082	0.641
CLV_PCSK_KEX2_1	6	8	PF00082	0.502
CLV_PCSK_PC1ET2_1	105	107	PF00082	0.648
CLV_PCSK_PC1ET2_1	196	198	PF00082	0.622
CLV_PCSK_PC1ET2_1	207	209	PF00082	0.629
CLV_PCSK_PC7_1	419	425	PF00082	0.515
CLV_PCSK_SKI1_1	196	200	PF00082	0.551
CLV_PCSK_SKI1_1	294	298	PF00082	0.493
CLV_PCSK_SKI1_1	371	375	PF00082	0.513
CLV_PCSK_SKI1_1	6	10	PF00082	0.493
CLV_PCSK_SKI1_1	678	682	PF00082	0.504
CLV_PCSK_SKI1_1	863	867	PF00082	0.565
CLV_PCSK_SKI1_1	871	875	PF00082	0.623
CLV_Separin_Metazoa	368	372	PF03568	0.502
CLV_Separin_Metazoa	80	84	PF03568	0.590
DEG_APCC_DBOX_1	677	685	PF00400	0.505
DEG_Nend_UBRbox_3	1	3	PF02207	0.516
DEG_ODPH_VHL_1	882	895	PF01847	0.526
DEG_SCF_FBW7_1	113	118	PF00400	0.653
DEG_SCF_FBW7_2	115	122	PF00400	0.695
DEG_SCF_SKP2-CKS1_1	813	820	PF00560	0.585
DEG_SPOP_SBC_1	265	269	PF00917	0.648
DEG_SPOP_SBC_1	321	325	PF00917	0.630
DEG_SPOP_SBC_1	797	801	PF00917	0.704
DEG_SPOP_SBC_1	929	933	PF00917	0.583
DEG_SPOP_SBC_1	975	979	PF00917	0.579
DOC_CKS1_1	116	121	PF01111	0.697
DOC_CKS1_1	170	175	PF01111	0.657
DOC_CKS1_1	999	1004	PF01111	0.511
DOC_CYCLIN_yCln2_LP_2	380	386	PF00134	0.508
DOC_CYCLIN_yCln2_LP_2	89	92	PF00134	0.612
DOC_MAPK_gen_1	820	828	PF00069	0.692
DOC_MAPK_gen_1	888	895	PF00069	0.587
DOC_PP2B_LxvP_1	488	491	PF13499	0.622
DOC_PP2B_LxvP_1	709	712	PF13499	0.656
DOC_PP2B_LxvP_1	724	727	PF13499	0.634
DOC_PP2B_LxvP_1	89	92	PF13499	0.612
DOC_PP2B_PxIxI_1	478	484	PF00149	0.585
DOC_PP4_FxxP_1	918	921	PF00568	0.598
DOC_PP4_FxxP_1	927	930	PF00568	0.612
DOC_USP7_MATH_1	135	139	PF00917	0.691
DOC_USP7_MATH_1	177	181	PF00917	0.640
DOC_USP7_MATH_1	200	204	PF00917	0.724
DOC_USP7_MATH_1	214	218	PF00917	0.728
DOC_USP7_MATH_1	246	250	PF00917	0.681
DOC_USP7_MATH_1	308	312	PF00917	0.571
DOC_USP7_MATH_1	384	388	PF00917	0.595
DOC_USP7_MATH_1	461	465	PF00917	0.567
DOC_USP7_MATH_1	516	520	PF00917	0.643
DOC_USP7_MATH_1	535	539	PF00917	0.532
DOC_USP7_MATH_1	570	574	PF00917	0.516
DOC_USP7_MATH_1	60	64	PF00917	0.665
DOC_USP7_MATH_1	654	658	PF00917	0.630
DOC_USP7_MATH_1	720	724	PF00917	0.618
DOC_USP7_MATH_1	74	78	PF00917	0.515
DOC_USP7_MATH_1	746	750	PF00917	0.697
DOC_USP7_MATH_1	765	769	PF00917	0.504
DOC_USP7_MATH_1	875	879	PF00917	0.555
DOC_USP7_MATH_1	899	903	PF00917	0.611
DOC_USP7_MATH_1	912	916	PF00917	0.541
DOC_USP7_MATH_1	930	934	PF00917	0.625
DOC_USP7_MATH_1	948	952	PF00917	0.506
DOC_USP7_MATH_1	994	998	PF00917	0.537
DOC_USP7_UBL2_3	133	137	PF12436	0.593
DOC_WW_Pin1_4	109	114	PF00397	0.808
DOC_WW_Pin1_4	115	120	PF00397	0.685
DOC_WW_Pin1_4	151	156	PF00397	0.688
DOC_WW_Pin1_4	169	174	PF00397	0.540
DOC_WW_Pin1_4	179	184	PF00397	0.584
DOC_WW_Pin1_4	218	223	PF00397	0.624
DOC_WW_Pin1_4	252	257	PF00397	0.642
DOC_WW_Pin1_4	360	365	PF00397	0.551
DOC_WW_Pin1_4	43	48	PF00397	0.613
DOC_WW_Pin1_4	492	497	PF00397	0.586
DOC_WW_Pin1_4	566	571	PF00397	0.613
DOC_WW_Pin1_4	572	577	PF00397	0.586
DOC_WW_Pin1_4	587	592	PF00397	0.769
DOC_WW_Pin1_4	601	606	PF00397	0.534
DOC_WW_Pin1_4	618	623	PF00397	0.604
DOC_WW_Pin1_4	63	68	PF00397	0.522
DOC_WW_Pin1_4	703	708	PF00397	0.604
DOC_WW_Pin1_4	715	720	PF00397	0.674
DOC_WW_Pin1_4	791	796	PF00397	0.634
DOC_WW_Pin1_4	814	819	PF00397	0.613
DOC_WW_Pin1_4	857	862	PF00397	0.683
DOC_WW_Pin1_4	882	887	PF00397	0.548
DOC_WW_Pin1_4	888	893	PF00397	0.582
DOC_WW_Pin1_4	910	915	PF00397	0.625
DOC_WW_Pin1_4	916	921	PF00397	0.640
DOC_WW_Pin1_4	931	936	PF00397	0.596
DOC_WW_Pin1_4	981	986	PF00397	0.587
DOC_WW_Pin1_4	998	1003	PF00397	0.665
LIG_14-3-3_CanoR_1	304	308	PF00244	0.579
LIG_14-3-3_CanoR_1	450	459	PF00244	0.446
LIG_14-3-3_CanoR_1	510	518	PF00244	0.639
LIG_14-3-3_CanoR_1	635	645	PF00244	0.571
LIG_14-3-3_CanoR_1	736	742	PF00244	0.545
LIG_14-3-3_CanoR_1	767	776	PF00244	0.494
LIG_14-3-3_CanoR_1	798	804	PF00244	0.697
LIG_14-3-3_CanoR_1	822	827	PF00244	0.691
LIG_AP2alpha_2	947	949	PF02296	0.546
LIG_BRCT_BRCA1_1	772	776	PF00533	0.489
LIG_BRCT_BRCA1_1	914	918	PF00533	0.581
LIG_deltaCOP1_diTrp_1	947	955	PF00928	0.533
LIG_FHA_1	199	205	PF00498	0.641
LIG_FHA_1	310	316	PF00498	0.510
LIG_FHA_1	331	337	PF00498	0.599
LIG_FHA_1	342	348	PF00498	0.440
LIG_FHA_1	461	467	PF00498	0.584
LIG_FHA_1	640	646	PF00498	0.605
LIG_FHA_1	666	672	PF00498	0.589
LIG_FHA_1	719	725	PF00498	0.627
LIG_FHA_1	753	759	PF00498	0.647
LIG_FHA_1	823	829	PF00498	0.690
LIG_FHA_1	99	105	PF00498	0.624
LIG_FHA_2	112	118	PF00498	0.568
LIG_FHA_2	142	148	PF00498	0.643
LIG_FHA_2	159	165	PF00498	0.648
LIG_FHA_2	173	179	PF00498	0.566
LIG_FHA_2	341	347	PF00498	0.663
LIG_FHA_2	407	413	PF00498	0.538
LIG_FHA_2	619	625	PF00498	0.613
LIG_IBAR_NPY_1	547	549	PF08397	0.527
LIG_LIR_Apic_2	915	921	PF02991	0.574
LIG_LIR_Gen_1	372	381	PF02991	0.549
LIG_LIR_Gen_1	569	578	PF02991	0.522
LIG_LIR_Gen_1	76	82	PF02991	0.557
LIG_LIR_Gen_1	951	956	PF02991	0.516
LIG_LIR_Gen_1	963	972	PF02991	0.495
LIG_LIR_Nem_3	372	377	PF02991	0.666
LIG_LIR_Nem_3	569	574	PF02991	0.515
LIG_LIR_Nem_3	632	637	PF02991	0.489
LIG_LIR_Nem_3	76	81	PF02991	0.561
LIG_LIR_Nem_3	773	779	PF02991	0.488
LIG_LIR_Nem_3	947	952	PF02991	0.542
LIG_LIR_Nem_3	963	969	PF02991	0.504
LIG_MYND_1	707	711	PF01753	0.536
LIG_PAM2_1	824	836	PF00658	0.685
LIG_Pex14_2	606	610	PF04695	0.566
LIG_SH2_CRK	476	480	PF00017	0.585
LIG_SH2_CRK	543	547	PF00017	0.592
LIG_SH2_CRK	966	970	PF00017	0.497
LIG_SH2_GRB2like	966	969	PF00017	0.552
LIG_SH2_SRC	966	969	PF00017	0.552
LIG_SH2_STAP1	952	956	PF00017	0.514
LIG_SH2_STAT3	427	430	PF00017	0.431
LIG_SH2_STAT5	299	302	PF00017	0.444
LIG_SH2_STAT5	427	430	PF00017	0.431
LIG_SH3_2	884	889	PF14604	0.684
LIG_SH3_3	101	107	PF00018	0.614
LIG_SH3_3	113	119	PF00018	0.633
LIG_SH3_3	304	310	PF00018	0.565
LIG_SH3_3	463	469	PF00018	0.546
LIG_SH3_3	484	490	PF00018	0.537
LIG_SH3_3	557	563	PF00018	0.587
LIG_SH3_3	599	605	PF00018	0.642
LIG_SH3_3	608	614	PF00018	0.541
LIG_SH3_3	64	70	PF00018	0.641
LIG_SH3_3	705	711	PF00018	0.637
LIG_SH3_3	815	821	PF00018	0.739
LIG_SH3_3	829	835	PF00018	0.591
LIG_SH3_3	869	875	PF00018	0.587
LIG_SH3_3	881	887	PF00018	0.623
LIG_SH3_3	892	898	PF00018	0.562
LIG_SH3_3	911	917	PF00018	0.535
LIG_SH3_3	932	938	PF00018	0.684
LIG_SUMO_SIM_anti_2	366	372	PF11976	0.436
LIG_SUMO_SIM_par_1	563	569	PF11976	0.500
LIG_SUMO_SIM_par_1	668	674	PF11976	0.573
LIG_TRAF2_1	120	123	PF00917	0.699
LIG_TRAF2_1	162	165	PF00917	0.774
LIG_TRAF2_1	233	236	PF00917	0.548
LIG_TRAF2_1	409	412	PF00917	0.499
LIG_TRAF2_1	674	677	PF00917	0.553
LIG_TRAF2_1	804	807	PF00917	0.622
LIG_UBA3_1	353	359	PF00899	0.342
LIG_UBA3_1	435	443	PF00899	0.488
LIG_WRC_WIRS_1	571	576	PF05994	0.525
MOD_CDK_SPxK_1	814	820	PF00069	0.645
MOD_CDK_SPxK_1	857	863	PF00069	0.662
MOD_CDK_SPxK_1	882	888	PF00069	0.529
MOD_CDK_SPxK_1	998	1004	PF00069	0.591
MOD_CDK_SPxxK_3	791	798	PF00069	0.637
MOD_CDK_SPxxK_3	882	889	PF00069	0.529
MOD_CDK_SPxxK_3	936	943	PF00069	0.573
MOD_CK1_1	179	185	PF00069	0.649
MOD_CK1_1	213	219	PF00069	0.569
MOD_CK1_1	311	317	PF00069	0.787
MOD_CK1_1	322	328	PF00069	0.622
MOD_CK1_1	340	346	PF00069	0.421
MOD_CK1_1	494	500	PF00069	0.657
MOD_CK1_1	566	572	PF00069	0.516
MOD_CK1_1	590	596	PF00069	0.606
MOD_CK1_1	63	69	PF00069	0.618
MOD_CK1_1	650	656	PF00069	0.767
MOD_CK1_1	737	743	PF00069	0.542
MOD_CK1_1	770	776	PF00069	0.621
MOD_CK1_1	796	802	PF00069	0.654
MOD_CK1_1	843	849	PF00069	0.646
MOD_CK1_1	859	865	PF00069	0.656
MOD_CK1_1	878	884	PF00069	0.516
MOD_CK1_1	919	925	PF00069	0.644
MOD_CK1_1	983	989	PF00069	0.732
MOD_CK2_1	111	117	PF00069	0.568
MOD_CK2_1	141	147	PF00069	0.664
MOD_CK2_1	151	157	PF00069	0.622
MOD_CK2_1	158	164	PF00069	0.718
MOD_CK2_1	230	236	PF00069	0.555
MOD_CK2_1	321	327	PF00069	0.722
MOD_CK2_1	340	346	PF00069	0.542
MOD_CK2_1	406	412	PF00069	0.548
MOD_CK2_1	516	522	PF00069	0.699
MOD_CK2_1	654	660	PF00069	0.763
MOD_CK2_1	671	677	PF00069	0.451
MOD_CK2_1	74	80	PF00069	0.592
MOD_CK2_1	779	785	PF00069	0.541
MOD_GlcNHglycan	137	140	PF01048	0.692
MOD_GlcNHglycan	14	17	PF01048	0.525
MOD_GlcNHglycan	178	182	PF01048	0.692
MOD_GlcNHglycan	183	186	PF01048	0.766
MOD_GlcNHglycan	204	207	PF01048	0.657
MOD_GlcNHglycan	211	215	PF01048	0.713
MOD_GlcNHglycan	216	219	PF01048	0.811
MOD_GlcNHglycan	248	251	PF01048	0.637
MOD_GlcNHglycan	268	271	PF01048	0.602
MOD_GlcNHglycan	286	289	PF01048	0.411
MOD_GlcNHglycan	384	387	PF01048	0.591
MOD_GlcNHglycan	394	397	PF01048	0.593
MOD_GlcNHglycan	463	466	PF01048	0.612
MOD_GlcNHglycan	512	515	PF01048	0.660
MOD_GlcNHglycan	62	65	PF01048	0.660
MOD_GlcNHglycan	665	668	PF01048	0.644
MOD_GlcNHglycan	795	798	PF01048	0.634
MOD_GlcNHglycan	875	878	PF01048	0.589
MOD_GlcNHglycan	92	95	PF01048	0.669
MOD_GlcNHglycan	922	925	PF01048	0.628
MOD_GlcNHglycan	943	946	PF01048	0.555
MOD_GlcNHglycan	985	988	PF01048	0.696
MOD_GlcNHglycan	996	999	PF01048	0.577
MOD_GSK3_1	107	114	PF00069	0.686
MOD_GSK3_1	135	142	PF00069	0.610
MOD_GSK3_1	149	156	PF00069	0.628
MOD_GSK3_1	168	175	PF00069	0.544
MOD_GSK3_1	177	184	PF00069	0.594
MOD_GSK3_1	198	205	PF00069	0.720
MOD_GSK3_1	206	213	PF00069	0.609
MOD_GSK3_1	214	221	PF00069	0.576
MOD_GSK3_1	242	249	PF00069	0.602
MOD_GSK3_1	319	326	PF00069	0.658
MOD_GSK3_1	337	344	PF00069	0.599
MOD_GSK3_1	54	61	PF00069	0.604
MOD_GSK3_1	566	573	PF00069	0.621
MOD_GSK3_1	644	651	PF00069	0.616
MOD_GSK3_1	654	661	PF00069	0.573
MOD_GSK3_1	714	721	PF00069	0.617
MOD_GSK3_1	730	737	PF00069	0.680
MOD_GSK3_1	742	749	PF00069	0.656
MOD_GSK3_1	750	757	PF00069	0.579
MOD_GSK3_1	793	800	PF00069	0.698
MOD_GSK3_1	810	817	PF00069	0.534
MOD_GSK3_1	841	848	PF00069	0.641
MOD_GSK3_1	853	860	PF00069	0.601
MOD_GSK3_1	873	880	PF00069	0.590
MOD_GSK3_1	912	919	PF00069	0.634
MOD_GSK3_1	975	982	PF00069	0.689
MOD_GSK3_1	994	1001	PF00069	0.510
MOD_N-GLC_1	241	246	PF02516	0.575
MOD_N-GLC_1	284	289	PF02516	0.486
MOD_N-GLC_1	663	668	PF02516	0.621
MOD_N-GLC_1	841	846	PF02516	0.628
MOD_NEK2_1	636	641	PF00069	0.485
MOD_NEK2_1	665	670	PF00069	0.633
MOD_NEK2_2	550	555	PF00069	0.555
MOD_PIKK_1	124	130	PF00454	0.539
MOD_PIKK_1	166	172	PF00454	0.699
MOD_PIKK_1	276	282	PF00454	0.685
MOD_PIKK_1	441	447	PF00454	0.505
MOD_PIKK_1	494	500	PF00454	0.656
MOD_PIKK_1	553	559	PF00454	0.579
MOD_PIKK_1	636	642	PF00454	0.559
MOD_PIKK_1	654	660	PF00454	0.527
MOD_PIKK_1	671	677	PF00454	0.488
MOD_PIKK_1	730	736	PF00454	0.586
MOD_PIKK_1	767	773	PF00454	0.632
MOD_PK_1	648	654	PF00069	0.518
MOD_PKA_2	242	248	PF00069	0.590
MOD_PKA_2	303	309	PF00069	0.574
MOD_PKA_2	797	803	PF00069	0.701
MOD_PKA_2	821	827	PF00069	0.692
MOD_PKB_1	448	456	PF00069	0.474
MOD_Plk_1	284	290	PF00069	0.484
MOD_Plk_1	302	308	PF00069	0.437
MOD_Plk_1	659	665	PF00069	0.761
MOD_Plk_4	550	556	PF00069	0.558
MOD_Plk_4	846	852	PF00069	0.572
MOD_Plk_4	99	105	PF00069	0.641
MOD_ProDKin_1	109	115	PF00069	0.804
MOD_ProDKin_1	151	157	PF00069	0.689
MOD_ProDKin_1	169	175	PF00069	0.540
MOD_ProDKin_1	179	185	PF00069	0.582
MOD_ProDKin_1	218	224	PF00069	0.623
MOD_ProDKin_1	252	258	PF00069	0.640
MOD_ProDKin_1	360	366	PF00069	0.544
MOD_ProDKin_1	43	49	PF00069	0.618
MOD_ProDKin_1	492	498	PF00069	0.587
MOD_ProDKin_1	566	572	PF00069	0.616
MOD_ProDKin_1	587	593	PF00069	0.782
MOD_ProDKin_1	601	607	PF00069	0.536
MOD_ProDKin_1	618	624	PF00069	0.601
MOD_ProDKin_1	63	69	PF00069	0.521
MOD_ProDKin_1	703	709	PF00069	0.605
MOD_ProDKin_1	715	721	PF00069	0.675
MOD_ProDKin_1	791	797	PF00069	0.635
MOD_ProDKin_1	814	820	PF00069	0.613
MOD_ProDKin_1	857	863	PF00069	0.683
MOD_ProDKin_1	882	888	PF00069	0.549
MOD_ProDKin_1	910	916	PF00069	0.625
MOD_ProDKin_1	931	937	PF00069	0.597
MOD_ProDKin_1	981	987	PF00069	0.585
MOD_ProDKin_1	998	1004	PF00069	0.665
MOD_SUMO_rev_2	19	27	PF00179	0.548
TRG_DiLeu_BaEn_4	676	682	PF01217	0.529
TRG_DiLeu_BaLyEn_6	291	296	PF01217	0.480
TRG_ENDOCYTIC_2	549	552	PF00928	0.581
TRG_ENDOCYTIC_2	952	955	PF00928	0.525
TRG_ENDOCYTIC_2	966	969	PF00928	0.494
TRG_ER_diArg_1	194	197	PF00400	0.622
TRG_ER_diArg_1	237	240	PF00400	0.541
TRG_ER_diArg_1	423	425	PF00400	0.450
TRG_ER_diArg_1	5	7	PF00400	0.510
TRG_ER_diArg_1	580	582	PF00400	0.641
TRG_NES_CRM1_1	346	360	PF08389	0.430
TRG_NLS_MonoCore_2	104	109	PF00514	0.631
TRG_NLS_MonoExtC_3	194	199	PF00514	0.621
TRG_NLS_MonoExtN_4	195	200	PF00514	0.619
TRG_Pf-PMV_PEXEL_1	371	375	PF00026	0.513
TRG_Pf-PMV_PEXEL_1	7	12	PF00026	0.493

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAC9	Leptomonas seymouri	40%	97%
A0A3S7WQR9	Leishmania donovani	85%	100%
A4H5S6	Leishmania braziliensis	63%	100%
A4HU20	Leishmania infantum	85%	100%
Q4QHS6	Leishmania major	84%	100%