Histone h1-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

histone h1-like protein

Species:

Leishmania mexicana

UniProt:

E9AMT9_LEIMU

TriTrypDb:

LmxM.09.0880

Length:

515

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 2, no: 4
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMT9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMT9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	163	165	PF00675	0.786
CLV_NRD_NRD_1	174	176	PF00675	0.574
CLV_NRD_NRD_1	182	184	PF00675	0.446
CLV_NRD_NRD_1	251	253	PF00675	0.476
CLV_NRD_NRD_1	325	327	PF00675	0.581
CLV_NRD_NRD_1	362	364	PF00675	0.615
CLV_NRD_NRD_1	431	433	PF00675	0.560
CLV_NRD_NRD_1	466	468	PF00675	0.682
CLV_NRD_NRD_1	497	499	PF00675	0.721
CLV_PCSK_KEX2_1	163	165	PF00082	0.786
CLV_PCSK_KEX2_1	174	176	PF00082	0.577
CLV_PCSK_KEX2_1	182	184	PF00082	0.443
CLV_PCSK_KEX2_1	251	253	PF00082	0.476
CLV_PCSK_KEX2_1	325	327	PF00082	0.499
CLV_PCSK_KEX2_1	339	341	PF00082	0.547
CLV_PCSK_KEX2_1	362	364	PF00082	0.636
CLV_PCSK_KEX2_1	431	433	PF00082	0.560
CLV_PCSK_KEX2_1	452	454	PF00082	0.586
CLV_PCSK_KEX2_1	504	506	PF00082	0.717
CLV_PCSK_KEX2_1	510	512	PF00082	0.631
CLV_PCSK_PC1ET2_1	339	341	PF00082	0.564
CLV_PCSK_PC1ET2_1	431	433	PF00082	0.515
CLV_PCSK_PC1ET2_1	452	454	PF00082	0.504
CLV_PCSK_PC1ET2_1	504	506	PF00082	0.638
CLV_PCSK_PC1ET2_1	510	512	PF00082	0.595
CLV_PCSK_PC7_1	427	433	PF00082	0.507
CLV_PCSK_SKI1_1	3	7	PF00082	0.545
CLV_PCSK_SKI1_1	363	367	PF00082	0.532
CLV_PCSK_SKI1_1	427	431	PF00082	0.551
CLV_PCSK_SKI1_1	468	472	PF00082	0.748
DEG_Nend_Nbox_1	1	3	PF02207	0.565
DOC_CYCLIN_yCln2_LP_2	302	308	PF00134	0.638
DOC_PP2B_LxvP_1	302	305	PF13499	0.643
DOC_USP7_MATH_1	127	131	PF00917	0.645
DOC_USP7_MATH_1	275	279	PF00917	0.600
DOC_USP7_MATH_1	367	371	PF00917	0.829
DOC_USP7_MATH_1	41	45	PF00917	0.699
DOC_USP7_MATH_1	46	50	PF00917	0.581
DOC_USP7_UBL2_3	319	323	PF12436	0.600
DOC_USP7_UBL2_3	396	400	PF12436	0.629
DOC_USP7_UBL2_3	448	452	PF12436	0.596
DOC_USP7_UBL2_3	455	459	PF12436	0.608
DOC_USP7_UBL2_3	464	468	PF12436	0.636
DOC_USP7_UBL2_3	471	475	PF12436	0.540
DOC_USP7_UBL2_3	499	503	PF12436	0.618
DOC_WW_Pin1_4	199	204	PF00397	0.490
DOC_WW_Pin1_4	353	358	PF00397	0.639
DOC_WW_Pin1_4	363	368	PF00397	0.645
DOC_WW_Pin1_4	410	415	PF00397	0.637
LIG_14-3-3_CanoR_1	240	247	PF00244	0.409
LIG_14-3-3_CanoR_1	263	269	PF00244	0.428
LIG_14-3-3_CanoR_1	325	334	PF00244	0.658
LIG_14-3-3_CanoR_1	432	436	PF00244	0.520
LIG_14-3-3_CanoR_1	477	485	PF00244	0.737
LIG_14-3-3_CanoR_1	486	495	PF00244	0.640
LIG_Clathr_ClatBox_1	86	90	PF01394	0.621
LIG_FHA_1	203	209	PF00498	0.473
LIG_FHA_2	240	246	PF00498	0.518
LIG_FHA_2	293	299	PF00498	0.750
LIG_LIR_LC3C_4	83	88	PF02991	0.483
LIG_LIR_Nem_3	97	103	PF02991	0.538
LIG_NRP_CendR_1	514	515	PF00754	0.656
LIG_Pex14_2	104	108	PF04695	0.527
LIG_SH2_STAT5	100	103	PF00017	0.542
LIG_SH3_3	197	203	PF00018	0.499
LIG_SH3_3	470	476	PF00018	0.711
LIG_SH3_4	464	471	PF00018	0.698
LIG_SH3_4	499	506	PF00018	0.502
LIG_SH3_CIN85_PxpxPR_1	357	362	PF14604	0.526
LIG_SUMO_SIM_par_1	85	92	PF11976	0.616
MOD_CDK_SPK_2	353	358	PF00069	0.656
MOD_CK1_1	147	153	PF00069	0.656
MOD_CK1_1	18	24	PF00069	0.594
MOD_CK1_1	188	194	PF00069	0.553
MOD_CK1_1	199	205	PF00069	0.447
MOD_CK1_1	280	286	PF00069	0.692
MOD_CK1_1	33	39	PF00069	0.685
MOD_CK1_1	49	55	PF00069	0.674
MOD_CK1_1	95	101	PF00069	0.493
MOD_CK2_1	239	245	PF00069	0.441
MOD_CK2_1	292	298	PF00069	0.653
MOD_DYRK1A_RPxSP_1	363	367	PF00069	0.532
MOD_GlcNHglycan	121	124	PF01048	0.641
MOD_GlcNHglycan	187	190	PF01048	0.544
MOD_GlcNHglycan	23	26	PF01048	0.677
MOD_GlcNHglycan	282	285	PF01048	0.596
MOD_GlcNHglycan	335	338	PF01048	0.504
MOD_GlcNHglycan	415	418	PF01048	0.649
MOD_GlcNHglycan	43	46	PF01048	0.490
MOD_GlcNHglycan	441	444	PF01048	0.509
MOD_GlcNHglycan	488	491	PF01048	0.621
MOD_GlcNHglycan	94	97	PF01048	0.550
MOD_GSK3_1	147	154	PF00069	0.561
MOD_GSK3_1	15	22	PF00069	0.622
MOD_GSK3_1	235	242	PF00069	0.519
MOD_GSK3_1	321	328	PF00069	0.641
MOD_GSK3_1	36	43	PF00069	0.650
MOD_GSK3_1	363	370	PF00069	0.687
MOD_GSK3_1	413	420	PF00069	0.598
MOD_GSK3_1	477	484	PF00069	0.638
MOD_GSK3_1	91	98	PF00069	0.453
MOD_N-GLC_1	223	228	PF02516	0.434
MOD_N-GLC_1	343	348	PF02516	0.480
MOD_N-GLC_1	353	358	PF02516	0.656
MOD_N-GLC_1	92	97	PF02516	0.586
MOD_NEK2_1	144	149	PF00069	0.483
MOD_NEK2_1	16	21	PF00069	0.695
MOD_NEK2_1	207	212	PF00069	0.459
MOD_NEK2_1	223	228	PF00069	0.434
MOD_NEK2_1	321	326	PF00069	0.465
MOD_NEK2_2	61	66	PF00069	0.692
MOD_PIKK_1	188	194	PF00454	0.478
MOD_PIKK_1	207	213	PF00454	0.457
MOD_PIKK_1	269	275	PF00454	0.620
MOD_PIKK_1	277	283	PF00454	0.509
MOD_PIKK_1	49	55	PF00454	0.640
MOD_PIKK_1	64	70	PF00454	0.492
MOD_PK_1	431	437	PF00069	0.517
MOD_PK_1	481	487	PF00069	0.654
MOD_PKA_1	325	331	PF00069	0.454
MOD_PKA_1	373	379	PF00069	0.648
MOD_PKA_1	431	437	PF00069	0.525
MOD_PKA_1	471	477	PF00069	0.588
MOD_PKA_1	504	510	PF00069	0.584
MOD_PKA_2	239	245	PF00069	0.434
MOD_PKA_2	325	331	PF00069	0.640
MOD_PKA_2	431	437	PF00069	0.527
MOD_PKA_2	476	482	PF00069	0.716
MOD_PKA_2	504	510	PF00069	0.712
MOD_PKA_2	6	12	PF00069	0.624
MOD_PKB_1	183	191	PF00069	0.548
MOD_Plk_1	144	150	PF00069	0.677
MOD_Plk_1	223	229	PF00069	0.436
MOD_Plk_1	33	39	PF00069	0.530
MOD_Plk_4	292	298	PF00069	0.653
MOD_Plk_4	330	336	PF00069	0.526
MOD_Plk_4	46	52	PF00069	0.604
MOD_Plk_4	491	497	PF00069	0.562
MOD_ProDKin_1	199	205	PF00069	0.484
MOD_ProDKin_1	353	359	PF00069	0.638
MOD_ProDKin_1	363	369	PF00069	0.644
MOD_ProDKin_1	410	416	PF00069	0.636
MOD_SUMO_for_1	230	233	PF00179	0.436
MOD_SUMO_rev_2	434	440	PF00179	0.515
TRG_ER_diArg_1	174	176	PF00400	0.580
TRG_ER_diArg_1	182	185	PF00400	0.426
TRG_ER_diArg_1	250	252	PF00400	0.495
TRG_ER_diArg_1	340	343	PF00400	0.655
TRG_ER_diArg_1	361	363	PF00400	0.607
TRG_ER_diArg_1	485	488	PF00400	0.627
TRG_NLS_Bipartite_1	325	343	PF00514	0.460
TRG_NLS_MonoCore_2	429	434	PF00514	0.508
TRG_NLS_MonoExtC_3	337	342	PF00514	0.513
TRG_NLS_MonoExtC_3	430	436	PF00514	0.539
TRG_NLS_MonoExtN_4	338	343	PF00514	0.506
TRG_NLS_MonoExtN_4	427	434	PF00514	0.570
TRG_NLS_MonoExtN_4	500	507	PF00514	0.552
TRG_Pf-PMV_PEXEL_1	111	115	PF00026	0.576

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILW1	Leptomonas seymouri	43%	100%
A0A3Q8I7H5	Leishmania donovani	80%	100%
A4H5N7	Leishmania braziliensis	67%	100%
A4HU09	Leishmania infantum	80%	100%
Q4QHT6	Leishmania major	80%	94%