Phosphoglycerate mutase family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Histidine phosphatase superfamily (branch 1), putative

Species:

Leishmania mexicana

UniProt:

E9AMQ7_LEIMU

TriTrypDb:

LmxM.09.0560

Length:

262

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMQ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMQ7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	183	185	PF00082	0.592
CLV_PCSK_PC1ET2_1	183	185	PF00082	0.592
CLV_PCSK_SKI1_1	183	187	PF00082	0.663
DOC_CDC14_PxL_1	185	193	PF14671	0.573
DOC_CKS1_1	250	255	PF01111	0.582
DOC_CYCLIN_yCln2_LP_2	150	156	PF00134	0.601
DOC_MAPK_MEF2A_6	141	150	PF00069	0.503
DOC_MAPK_MEF2A_6	90	98	PF00069	0.567
DOC_PP2B_LxvP_1	186	189	PF13499	0.579
DOC_PP4_FxxP_1	127	130	PF00568	0.578
DOC_PP4_FxxP_1	250	253	PF00568	0.587
DOC_USP7_MATH_1	179	183	PF00917	0.468
DOC_USP7_MATH_1	85	89	PF00917	0.640
DOC_USP7_MATH_1	9	13	PF00917	0.474
DOC_WW_Pin1_4	142	147	PF00397	0.501
DOC_WW_Pin1_4	220	225	PF00397	0.630
DOC_WW_Pin1_4	249	254	PF00397	0.555
DOC_WW_Pin1_4	29	34	PF00397	0.480
DOC_WW_Pin1_4	62	67	PF00397	0.426
LIG_14-3-3_CanoR_1	10	18	PF00244	0.551
LIG_14-3-3_CanoR_1	141	146	PF00244	0.579
LIG_14-3-3_CanoR_1	242	246	PF00244	0.606
LIG_14-3-3_CanoR_1	249	253	PF00244	0.500
LIG_14-3-3_CanoR_1	69	78	PF00244	0.426
LIG_Actin_WH2_2	56	71	PF00022	0.544
LIG_APCC_ABBA_1	94	99	PF00400	0.467
LIG_EH_1	151	155	PF12763	0.608
LIG_FHA_1	193	199	PF00498	0.574
LIG_FHA_1	225	231	PF00498	0.480
LIG_FHA_1	250	256	PF00498	0.595
LIG_FHA_1	62	68	PF00498	0.422
LIG_FHA_1	77	83	PF00498	0.592
LIG_FHA_1	91	97	PF00498	0.553
LIG_FHA_2	161	167	PF00498	0.581
LIG_GBD_Chelix_1	41	49	PF00786	0.480
LIG_LIR_Apic_2	124	130	PF02991	0.573
LIG_LIR_Apic_2	248	253	PF02991	0.615
LIG_LIR_Apic_2	25	29	PF02991	0.480
LIG_LIR_Gen_1	227	235	PF02991	0.461
LIG_LIR_Gen_1	244	255	PF02991	0.518
LIG_LIR_Nem_3	104	110	PF02991	0.454
LIG_LIR_Nem_3	223	229	PF02991	0.516
LIG_LIR_Nem_3	244	250	PF02991	0.672
LIG_SH2_CRK	26	30	PF00017	0.551
LIG_SH2_NCK_1	134	138	PF00017	0.575
LIG_SH2_SRC	97	100	PF00017	0.499
LIG_SH2_STAT5	226	229	PF00017	0.484
LIG_SH2_STAT5	48	51	PF00017	0.426
LIG_SH2_STAT5	97	100	PF00017	0.521
LIG_SH3_3	116	122	PF00018	0.599
LIG_SH3_3	152	158	PF00018	0.590
LIG_SH3_3	250	256	PF00018	0.576
LIG_SUMO_SIM_anti_2	195	200	PF11976	0.596
LIG_SUMO_SIM_anti_2	59	65	PF11976	0.517
LIG_SUMO_SIM_par_1	184	190	PF11976	0.653
LIG_SUMO_SIM_par_1	59	65	PF11976	0.480
LIG_TRFH_1	154	158	PF08558	0.531
MOD_CDK_SPxxK_3	62	69	PF00069	0.426
MOD_CK1_1	32	38	PF00069	0.480
MOD_CK2_1	115	121	PF00069	0.666
MOD_CK2_1	170	176	PF00069	0.567
MOD_CK2_1	234	240	PF00069	0.627
MOD_GlcNHglycan	235	239	PF01048	0.634
MOD_GlcNHglycan	87	90	PF01048	0.631
MOD_GSK3_1	220	227	PF00069	0.593
MOD_GSK3_1	230	237	PF00069	0.475
MOD_NEK2_1	169	174	PF00069	0.517
MOD_NEK2_1	22	27	PF00069	0.480
MOD_PKA_2	140	146	PF00069	0.611
MOD_PKA_2	241	247	PF00069	0.609
MOD_PKA_2	248	254	PF00069	0.496
MOD_PKA_2	9	15	PF00069	0.480
MOD_Plk_1	170	176	PF00069	0.560
MOD_Plk_4	115	121	PF00069	0.665
MOD_Plk_4	192	198	PF00069	0.582
MOD_Plk_4	201	207	PF00069	0.496
MOD_ProDKin_1	142	148	PF00069	0.495
MOD_ProDKin_1	220	226	PF00069	0.616
MOD_ProDKin_1	249	255	PF00069	0.552
MOD_ProDKin_1	29	35	PF00069	0.480
MOD_ProDKin_1	62	68	PF00069	0.426
MOD_SUMO_for_1	217	220	PF00179	0.456
MOD_SUMO_rev_2	165	170	PF00179	0.372
MOD_SUMO_rev_2	190	196	PF00179	0.631
TRG_DiLeu_BaEn_1	165	170	PF01217	0.421
TRG_DiLeu_BaLyEn_6	181	186	PF01217	0.560
TRG_DiLeu_BaLyEn_6	63	68	PF01217	0.537
TRG_ENDOCYTIC_2	107	110	PF00928	0.541
TRG_ENDOCYTIC_2	226	229	PF00928	0.484
TRG_ENDOCYTIC_2	247	250	PF00928	0.592

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4Q9	Leptomonas seymouri	61%	100%
A0A0S4JZY4	Bodo saltans	37%	91%
A0A3S7WQN5	Leishmania donovani	94%	100%
A4H5N3	Leishmania braziliensis	79%	100%
A4HTX7	Leishmania infantum	94%	100%
Q4QHW8	Leishmania major	91%	100%