Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AMQ5_LEIMU

TriTrypDb:

LmxM.09.0540

Length:

1099

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMQ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMQ5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	281	285	PF00656	0.581
CLV_C14_Caspase3-7	55	59	PF00656	0.646
CLV_NRD_NRD_1	113	115	PF00675	0.748
CLV_NRD_NRD_1	15	17	PF00675	0.741
CLV_NRD_NRD_1	31	33	PF00675	0.511
CLV_NRD_NRD_1	323	325	PF00675	0.707
CLV_NRD_NRD_1	391	393	PF00675	0.771
CLV_NRD_NRD_1	468	470	PF00675	0.577
CLV_NRD_NRD_1	513	515	PF00675	0.697
CLV_NRD_NRD_1	604	606	PF00675	0.647
CLV_NRD_NRD_1	623	625	PF00675	0.649
CLV_NRD_NRD_1	638	640	PF00675	0.664
CLV_NRD_NRD_1	657	659	PF00675	0.546
CLV_NRD_NRD_1	916	918	PF00675	0.701
CLV_NRD_NRD_1	943	945	PF00675	0.447
CLV_NRD_NRD_1	958	960	PF00675	0.639
CLV_PCSK_FUR_1	956	960	PF00082	0.604
CLV_PCSK_KEX2_1	113	115	PF00082	0.748
CLV_PCSK_KEX2_1	15	17	PF00082	0.741
CLV_PCSK_KEX2_1	258	260	PF00082	0.733
CLV_PCSK_KEX2_1	31	33	PF00082	0.511
CLV_PCSK_KEX2_1	323	325	PF00082	0.707
CLV_PCSK_KEX2_1	390	392	PF00082	0.765
CLV_PCSK_KEX2_1	468	470	PF00082	0.631
CLV_PCSK_KEX2_1	604	606	PF00082	0.707
CLV_PCSK_KEX2_1	623	625	PF00082	0.589
CLV_PCSK_KEX2_1	638	640	PF00082	0.589
CLV_PCSK_KEX2_1	808	810	PF00082	0.636
CLV_PCSK_KEX2_1	916	918	PF00082	0.701
CLV_PCSK_KEX2_1	958	960	PF00082	0.723
CLV_PCSK_PC1ET2_1	258	260	PF00082	0.733
CLV_PCSK_PC1ET2_1	808	810	PF00082	0.620
CLV_PCSK_SKI1_1	161	165	PF00082	0.627
CLV_PCSK_SKI1_1	277	281	PF00082	0.688
CLV_PCSK_SKI1_1	708	712	PF00082	0.521
CLV_PCSK_SKI1_1	73	77	PF00082	0.673
CLV_PCSK_SKI1_1	853	857	PF00082	0.687
DEG_SPOP_SBC_1	1072	1076	PF00917	0.606
DEG_SPOP_SBC_1	350	354	PF00917	0.555
DOC_ANK_TNKS_1	316	323	PF00023	0.567
DOC_CKS1_1	94	99	PF01111	0.671
DOC_MAPK_gen_1	31	38	PF00069	0.621
DOC_MAPK_MEF2A_6	233	240	PF00069	0.672
DOC_MAPK_MEF2A_6	73	81	PF00069	0.678
DOC_PP2B_PxIxI_1	235	241	PF00149	0.543
DOC_USP7_MATH_1	1066	1070	PF00917	0.674
DOC_USP7_MATH_1	1084	1088	PF00917	0.534
DOC_USP7_MATH_1	1090	1094	PF00917	0.607
DOC_USP7_MATH_1	219	223	PF00917	0.734
DOC_USP7_MATH_1	245	249	PF00917	0.680
DOC_USP7_MATH_1	251	255	PF00917	0.673
DOC_USP7_MATH_1	261	265	PF00917	0.658
DOC_USP7_MATH_1	302	306	PF00917	0.691
DOC_USP7_MATH_1	333	337	PF00917	0.677
DOC_USP7_MATH_1	366	370	PF00917	0.793
DOC_USP7_MATH_1	4	8	PF00917	0.745
DOC_USP7_MATH_1	448	452	PF00917	0.652
DOC_USP7_MATH_1	474	478	PF00917	0.713
DOC_USP7_MATH_1	546	550	PF00917	0.796
DOC_USP7_MATH_1	580	584	PF00917	0.675
DOC_USP7_MATH_1	598	602	PF00917	0.608
DOC_USP7_MATH_1	611	615	PF00917	0.722
DOC_USP7_MATH_1	717	721	PF00917	0.654
DOC_USP7_MATH_1	735	739	PF00917	0.481
DOC_USP7_MATH_1	848	852	PF00917	0.636
DOC_USP7_MATH_1	865	869	PF00917	0.682
DOC_USP7_MATH_1	88	92	PF00917	0.691
DOC_USP7_MATH_1	965	969	PF00917	0.708
DOC_WW_Pin1_4	16	21	PF00397	0.719
DOC_WW_Pin1_4	215	220	PF00397	0.732
DOC_WW_Pin1_4	259	264	PF00397	0.535
DOC_WW_Pin1_4	270	275	PF00397	0.732
DOC_WW_Pin1_4	344	349	PF00397	0.728
DOC_WW_Pin1_4	351	356	PF00397	0.581
DOC_WW_Pin1_4	524	529	PF00397	0.666
DOC_WW_Pin1_4	538	543	PF00397	0.569
DOC_WW_Pin1_4	563	568	PF00397	0.623
DOC_WW_Pin1_4	573	578	PF00397	0.579
DOC_WW_Pin1_4	918	923	PF00397	0.700
DOC_WW_Pin1_4	93	98	PF00397	0.673
DOC_WW_Pin1_4	99	104	PF00397	0.561
LIG_14-3-3_CanoR_1	113	119	PF00244	0.593
LIG_14-3-3_CanoR_1	210	219	PF00244	0.670
LIG_14-3-3_CanoR_1	277	287	PF00244	0.693
LIG_14-3-3_CanoR_1	323	328	PF00244	0.707
LIG_14-3-3_CanoR_1	358	362	PF00244	0.695
LIG_14-3-3_CanoR_1	586	596	PF00244	0.645
LIG_14-3-3_CanoR_1	708	718	PF00244	0.527
LIG_14-3-3_CanoR_1	867	873	PF00244	0.656
LIG_AP2alpha_2	479	481	PF02296	0.657
LIG_APCC_ABBA_1	729	734	PF00400	0.605
LIG_BIR_III_2	597	601	PF00653	0.558
LIG_BIR_III_4	162	166	PF00653	0.680
LIG_BIR_III_4	319	323	PF00653	0.565
LIG_BRCT_BRCA1_1	814	818	PF00533	0.670
LIG_eIF4E_1	966	972	PF01652	0.655
LIG_FHA_1	17	23	PF00498	0.723
LIG_FHA_1	64	70	PF00498	0.688
LIG_FHA_1	737	743	PF00498	0.614
LIG_FHA_1	823	829	PF00498	0.773
LIG_FHA_1	965	971	PF00498	0.661
LIG_FHA_2	362	368	PF00498	0.657
LIG_FHA_2	481	487	PF00498	0.707
LIG_FHA_2	722	728	PF00498	0.544
LIG_FHA_2	971	977	PF00498	0.659
LIG_Integrin_isoDGR_2	656	658	PF01839	0.692
LIG_Integrin_RGD_1	605	607	PF01839	0.568
LIG_LIR_Gen_1	726	735	PF02991	0.533
LIG_LIR_Gen_1	990	1001	PF02991	0.511
LIG_LIR_Nem_3	726	731	PF02991	0.585
LIG_LIR_Nem_3	74	79	PF02991	0.676
LIG_LIR_Nem_3	990	996	PF02991	0.595
LIG_MYND_1	878	882	PF01753	0.633
LIG_PDZ_Class_2	1094	1099	PF00595	0.613
LIG_Pex14_2	933	937	PF04695	0.601
LIG_RPA_C_Fungi	205	217	PF08784	0.681
LIG_RPA_C_Fungi	312	324	PF08784	0.566
LIG_RPA_C_Fungi	463	475	PF08784	0.580
LIG_SH2_CRK	836	840	PF00017	0.700
LIG_SH2_CRK	966	970	PF00017	0.657
LIG_SH2_NCK_1	482	486	PF00017	0.706
LIG_SH2_NCK_1	836	840	PF00017	0.700
LIG_SH2_STAP1	966	970	PF00017	0.609
LIG_SH2_STAT3	173	176	PF00017	0.678
LIG_SH2_STAT3	307	310	PF00017	0.688
LIG_SH2_STAT5	482	485	PF00017	0.706
LIG_SH2_STAT5	789	792	PF00017	0.635
LIG_SH2_STAT5	903	906	PF00017	0.617
LIG_SH2_STAT5	931	934	PF00017	0.644
LIG_SH2_STAT5	966	969	PF00017	0.660
LIG_SH2_STAT5	993	996	PF00017	0.610
LIG_SH3_1	605	611	PF00018	0.555
LIG_SH3_1	821	827	PF00018	0.629
LIG_SH3_1	875	881	PF00018	0.724
LIG_SH3_3	1047	1053	PF00018	0.528
LIG_SH3_3	109	115	PF00018	0.685
LIG_SH3_3	237	243	PF00018	0.757
LIG_SH3_3	345	351	PF00018	0.651
LIG_SH3_3	561	567	PF00018	0.668
LIG_SH3_3	605	611	PF00018	0.555
LIG_SH3_3	74	80	PF00018	0.796
LIG_SH3_3	821	827	PF00018	0.737
LIG_SH3_3	875	881	PF00018	0.724
LIG_SUMO_SIM_anti_2	967	974	PF11976	0.654
LIG_SUMO_SIM_par_1	967	974	PF11976	0.654
LIG_TRAF2_1	1029	1032	PF00917	0.626
LIG_TRAF2_1	286	289	PF00917	0.642
LIG_TRAF2_1	296	299	PF00917	0.658
LIG_TRAF2_1	308	311	PF00917	0.595
LIG_TRFH_1	76	80	PF08558	0.677
LIG_WW_3	166	170	PF00397	0.743
LIG_WW_3	562	566	PF00397	0.726
LIG_WW_3	838	842	PF00397	0.658
MOD_CAAXbox	1096	1099	PF01239	0.611
MOD_CDC14_SPxK_1	541	544	PF00782	0.546
MOD_CDK_SPxK_1	538	544	PF00069	0.548
MOD_CDK_SPxxK_3	270	277	PF00069	0.685
MOD_CDK_SPxxK_3	351	358	PF00069	0.556
MOD_CDK_SPxxK_3	93	100	PF00069	0.539
MOD_CK1_1	116	122	PF00069	0.624
MOD_CK1_1	141	147	PF00069	0.576
MOD_CK1_1	211	217	PF00069	0.674
MOD_CK1_1	227	233	PF00069	0.558
MOD_CK1_1	252	258	PF00069	0.721
MOD_CK1_1	282	288	PF00069	0.665
MOD_CK1_1	360	366	PF00069	0.631
MOD_CK1_1	369	375	PF00069	0.719
MOD_CK1_1	41	47	PF00069	0.569
MOD_CK1_1	422	428	PF00069	0.737
MOD_CK1_1	453	459	PF00069	0.647
MOD_CK1_1	573	579	PF00069	0.786
MOD_CK1_1	581	587	PF00069	0.806
MOD_CK1_1	7	13	PF00069	0.744
MOD_CK1_1	721	727	PF00069	0.600
MOD_CK1_1	822	828	PF00069	0.780
MOD_CK1_1	868	874	PF00069	0.723
MOD_CK1_1	905	911	PF00069	0.819
MOD_CK1_1	98	104	PF00069	0.654
MOD_CK2_1	215	221	PF00069	0.733
MOD_CK2_1	282	288	PF00069	0.705
MOD_CK2_1	361	367	PF00069	0.658
MOD_CK2_1	383	389	PF00069	0.552
MOD_CK2_1	516	522	PF00069	0.707
MOD_CK2_1	587	593	PF00069	0.804
MOD_CK2_1	611	617	PF00069	0.558
MOD_CK2_1	700	706	PF00069	0.607
MOD_CK2_1	717	723	PF00069	0.519
MOD_Cter_Amidation	321	324	PF01082	0.707
MOD_Cter_Amidation	656	659	PF01082	0.692
MOD_DYRK1A_RPxSP_1	259	263	PF00069	0.534
MOD_GlcNHglycan	1088	1091	PF01048	0.656
MOD_GlcNHglycan	128	131	PF01048	0.692
MOD_GlcNHglycan	210	213	PF01048	0.709
MOD_GlcNHglycan	228	232	PF01048	0.579
MOD_GlcNHglycan	281	284	PF01048	0.575
MOD_GlcNHglycan	376	379	PF01048	0.604
MOD_GlcNHglycan	393	396	PF01048	0.639
MOD_GlcNHglycan	421	424	PF01048	0.740
MOD_GlcNHglycan	48	51	PF01048	0.668
MOD_GlcNHglycan	502	505	PF01048	0.693
MOD_GlcNHglycan	547	551	PF01048	0.697
MOD_GlcNHglycan	556	559	PF01048	0.603
MOD_GlcNHglycan	569	573	PF01048	0.762
MOD_GlcNHglycan	702	705	PF01048	0.668
MOD_GlcNHglycan	73	76	PF01048	0.674
MOD_GlcNHglycan	798	801	PF01048	0.452
MOD_GlcNHglycan	814	817	PF01048	0.773
MOD_GlcNHglycan	836	839	PF01048	0.726
MOD_GlcNHglycan	850	853	PF01048	0.580
MOD_GlcNHglycan	870	873	PF01048	0.727
MOD_GlcNHglycan	88	91	PF01048	0.547
MOD_GlcNHglycan	894	897	PF01048	0.728
MOD_GlcNHglycan	899	902	PF01048	0.691
MOD_GlcNHglycan	909	912	PF01048	0.598
MOD_GSK3_1	1067	1074	PF00069	0.656
MOD_GSK3_1	1086	1093	PF00069	0.566
MOD_GSK3_1	114	121	PF00069	0.521
MOD_GSK3_1	157	164	PF00069	0.615
MOD_GSK3_1	211	218	PF00069	0.710
MOD_GSK3_1	219	226	PF00069	0.656
MOD_GSK3_1	23	30	PF00069	0.524
MOD_GSK3_1	245	252	PF00069	0.655
MOD_GSK3_1	261	268	PF00069	0.702
MOD_GSK3_1	278	285	PF00069	0.583
MOD_GSK3_1	302	309	PF00069	0.737
MOD_GSK3_1	349	356	PF00069	0.712
MOD_GSK3_1	357	364	PF00069	0.706
MOD_GSK3_1	366	373	PF00069	0.676
MOD_GSK3_1	38	45	PF00069	0.537
MOD_GSK3_1	422	429	PF00069	0.688
MOD_GSK3_1	487	494	PF00069	0.700
MOD_GSK3_1	505	512	PF00069	0.667
MOD_GSK3_1	578	585	PF00069	0.757
MOD_GSK3_1	7	14	PF00069	0.732
MOD_GSK3_1	717	724	PF00069	0.594
MOD_GSK3_1	736	743	PF00069	0.590
MOD_GSK3_1	867	874	PF00069	0.715
MOD_GSK3_1	899	906	PF00069	0.801
MOD_GSK3_1	918	925	PF00069	0.632
MOD_GSK3_1	95	102	PF00069	0.720
MOD_N-GLC_1	1017	1022	PF02516	0.666
MOD_N-GLC_1	141	146	PF02516	0.648
MOD_N-GLC_1	505	510	PF02516	0.508
MOD_NEK2_1	1002	1007	PF00069	0.610
MOD_NEK2_1	118	123	PF00069	0.542
MOD_NEK2_1	38	43	PF00069	0.546
MOD_NEK2_1	46	51	PF00069	0.607
MOD_NEK2_1	491	496	PF00069	0.673
MOD_NEK2_1	500	505	PF00069	0.603
MOD_NEK2_1	578	583	PF00069	0.696
MOD_NEK2_1	755	760	PF00069	0.659
MOD_NEK2_1	796	801	PF00069	0.412
MOD_NEK2_1	834	839	PF00069	0.701
MOD_NEK2_1	866	871	PF00069	0.799
MOD_NEK2_1	873	878	PF00069	0.677
MOD_NEK2_1	970	975	PF00069	0.746
MOD_NEK2_2	1017	1022	PF00069	0.666
MOD_NEK2_2	333	338	PF00069	0.622
MOD_NEK2_2	435	440	PF00069	0.674
MOD_PIKK_1	261	267	PF00454	0.670
MOD_PIKK_1	306	312	PF00454	0.748
MOD_PIKK_1	323	329	PF00454	0.566
MOD_PIKK_1	38	44	PF00454	0.556
MOD_PIKK_1	453	459	PF00454	0.657
MOD_PIKK_1	48	54	PF00454	0.560
MOD_PIKK_1	509	515	PF00454	0.511
MOD_PIKK_1	535	541	PF00454	0.622
MOD_PIKK_1	598	604	PF00454	0.695
MOD_PIKK_1	721	727	PF00454	0.525
MOD_PIKK_1	749	755	PF00454	0.643
MOD_PIKK_1	777	783	PF00454	0.524
MOD_PIKK_1	995	1001	PF00454	0.624
MOD_PKA_1	113	119	PF00069	0.701
MOD_PKA_1	323	329	PF00069	0.699
MOD_PKA_1	391	397	PF00069	0.546
MOD_PKA_1	468	474	PF00069	0.580
MOD_PKA_2	113	119	PF00069	0.756
MOD_PKA_2	157	163	PF00069	0.613
MOD_PKA_2	302	308	PF00069	0.736
MOD_PKA_2	323	329	PF00069	0.783
MOD_PKA_2	357	363	PF00069	0.694
MOD_PKA_2	391	397	PF00069	0.669
MOD_PKA_2	468	474	PF00069	0.699
MOD_PKA_2	581	587	PF00069	0.684
MOD_PKA_2	811	817	PF00069	0.700
MOD_PKA_2	866	872	PF00069	0.655
MOD_Plk_1	1017	1023	PF00069	0.672
MOD_Plk_1	190	196	PF00069	0.593
MOD_Plk_1	283	289	PF00069	0.637
MOD_Plk_1	366	372	PF00069	0.647
MOD_Plk_1	777	783	PF00069	0.524
MOD_Plk_2-3	224	230	PF00069	0.558
MOD_Plk_4	119	125	PF00069	0.703
MOD_Plk_4	366	372	PF00069	0.681
MOD_Plk_4	398	404	PF00069	0.716
MOD_Plk_4	487	493	PF00069	0.698
MOD_Plk_4	516	522	PF00069	0.707
MOD_Plk_4	63	69	PF00069	0.688
MOD_Plk_4	899	905	PF00069	0.532
MOD_Plk_4	965	971	PF00069	0.613
MOD_ProDKin_1	101	107	PF00069	0.591
MOD_ProDKin_1	16	22	PF00069	0.717
MOD_ProDKin_1	215	221	PF00069	0.733
MOD_ProDKin_1	259	265	PF00069	0.538
MOD_ProDKin_1	270	276	PF00069	0.733
MOD_ProDKin_1	344	350	PF00069	0.729
MOD_ProDKin_1	351	357	PF00069	0.582
MOD_ProDKin_1	524	530	PF00069	0.670
MOD_ProDKin_1	538	544	PF00069	0.571
MOD_ProDKin_1	563	569	PF00069	0.626
MOD_ProDKin_1	573	579	PF00069	0.579
MOD_ProDKin_1	918	924	PF00069	0.697
MOD_ProDKin_1	93	99	PF00069	0.672
TRG_DiLeu_BaLyEn_6	1022	1027	PF01217	0.710
TRG_DiLeu_BaLyEn_6	17	22	PF01217	0.725
TRG_DiLeu_BaLyEn_6	574	579	PF01217	0.555
TRG_DiLeu_BaLyEn_6	74	79	PF01217	0.676
TRG_ENDOCYTIC_2	966	969	PF00928	0.660
TRG_ENDOCYTIC_2	993	996	PF00928	0.610
TRG_ER_diArg_1	112	114	PF00400	0.754
TRG_ER_diArg_1	153	156	PF00400	0.663
TRG_ER_diArg_1	168	171	PF00400	0.676
TRG_ER_diArg_1	300	303	PF00400	0.691
TRG_ER_diArg_1	390	392	PF00400	0.632
TRG_ER_diArg_1	915	917	PF00400	0.709
TRG_ER_diArg_1	956	959	PF00400	0.602
TRG_NLS_Bipartite_1	623	643	PF00514	0.559
TRG_NLS_MonoExtC_3	638	643	PF00514	0.566
TRG_NLS_MonoExtN_4	636	643	PF00514	0.566
TRG_Pf-PMV_PEXEL_1	196	200	PF00026	0.601
TRG_Pf-PMV_PEXEL_1	949	954	PF00026	0.625

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGY4	Leishmania donovani	79%	99%
A4H5N1	Leishmania braziliensis	56%	98%
A4HTW8	Leishmania infantum	80%	99%
Q4QHX0	Leishmania major	80%	100%