Autophagy-related protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

ATG8/AUT7/APG8/PAZ2, putative

Species:

Leishmania mexicana

UniProt:

E9AML7_LEIMU

TriTrypDb:

LmxM.09.0180

Length:

343

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9AML7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AML7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	145	147	PF00675	0.862
CLV_NRD_NRD_1	161	163	PF00675	0.549
CLV_NRD_NRD_1	77	79	PF00675	0.769
CLV_PCSK_FUR_1	142	146	PF00082	0.855
CLV_PCSK_KEX2_1	144	146	PF00082	0.862
CLV_PCSK_KEX2_1	161	163	PF00082	0.532
CLV_PCSK_KEX2_1	79	81	PF00082	0.775
CLV_PCSK_PC1ET2_1	79	81	PF00082	0.775
CLV_PCSK_PC7_1	75	81	PF00082	0.768
CLV_PCSK_SKI1_1	232	236	PF00082	0.643
CLV_PCSK_SKI1_1	287	291	PF00082	0.655
DEG_APCC_DBOX_1	168	176	PF00400	0.823
DEG_Nend_UBRbox_4	1	3	PF02207	0.806
DEG_SCF_FBW7_1	175	182	PF00400	0.815
DEG_SCF_FBW7_1	333	339	PF00400	0.759
DEG_SPOP_SBC_1	41	45	PF00917	0.799
DOC_CKS1_1	225	230	PF01111	0.669
DOC_CKS1_1	333	338	PF01111	0.758
DOC_CYCLIN_yCln2_LP_2	225	231	PF00134	0.667
DOC_CYCLIN_yCln2_LP_2	31	37	PF00134	0.813
DOC_MAPK_DCC_7	27	37	PF00069	0.805
DOC_MAPK_gen_1	100	109	PF00069	0.746
DOC_MAPK_gen_1	286	293	PF00069	0.659
DOC_MAPK_JIP1_4	287	293	PF00069	0.649
DOC_MAPK_MEF2A_6	103	111	PF00069	0.742
DOC_MAPK_MEF2A_6	240	249	PF00069	0.652
DOC_MAPK_MEF2A_6	27	35	PF00069	0.800
DOC_MAPK_MEF2A_6	286	293	PF00069	0.659
DOC_PP2B_LxvP_1	31	34	PF13499	0.804
DOC_PP2B_LxvP_1	35	38	PF13499	0.745
DOC_PP4_FxxP_1	130	133	PF00568	0.803
DOC_PP4_FxxP_1	186	189	PF00568	0.831
DOC_USP7_MATH_1	13	17	PF00917	0.794
DOC_USP7_MATH_1	179	183	PF00917	0.815
DOC_USP7_MATH_1	202	206	PF00917	0.868
DOC_USP7_MATH_1	25	29	PF00917	0.581
DOC_USP7_MATH_1	294	298	PF00917	0.670
DOC_USP7_MATH_1	325	329	PF00917	0.704
DOC_USP7_MATH_1	336	340	PF00917	0.565
DOC_USP7_MATH_1	42	46	PF00917	0.506
DOC_USP7_MATH_1	93	97	PF00917	0.774
DOC_WW_Pin1_4	175	180	PF00397	0.820
DOC_WW_Pin1_4	191	196	PF00397	0.559
DOC_WW_Pin1_4	204	209	PF00397	0.640
DOC_WW_Pin1_4	224	229	PF00397	0.311
DOC_WW_Pin1_4	296	301	PF00397	0.677
DOC_WW_Pin1_4	332	337	PF00397	0.762
DOC_WW_Pin1_4	37	42	PF00397	0.799
LIG_14-3-3_CanoR_1	103	108	PF00244	0.740
LIG_14-3-3_CanoR_1	144	153	PF00244	0.855
LIG_14-3-3_CanoR_1	155	160	PF00244	0.647
LIG_14-3-3_CanoR_1	180	189	PF00244	0.823
LIG_14-3-3_CanoR_1	7	11	PF00244	0.775
LIG_Actin_WH2_2	226	242	PF00022	0.664
LIG_EH1_1	51	59	PF00400	0.810
LIG_FHA_1	113	119	PF00498	0.772
LIG_FHA_1	183	189	PF00498	0.827
LIG_FHA_1	288	294	PF00498	0.646
LIG_FHA_1	89	95	PF00498	0.781
LIG_FHA_2	225	231	PF00498	0.667
LIG_FHA_2	301	307	PF00498	0.636
LIG_LIR_Apic_2	184	189	PF02991	0.827
LIG_LIR_Nem_3	96	102	PF02991	0.760
LIG_MYND_1	34	38	PF01753	0.811
LIG_SH2_CRK	99	103	PF00017	0.758
LIG_SH2_STAT5	223	226	PF00017	0.660
LIG_SH2_STAT5	320	323	PF00017	0.601
LIG_SH3_3	186	192	PF00018	0.833
LIG_SH3_3	196	202	PF00018	0.670
LIG_SH3_3	207	213	PF00018	0.658
LIG_SH3_3	35	41	PF00018	0.809
LIG_SH3_3	5	11	PF00018	0.779
LIG_SUMO_SIM_par_1	245	251	PF11976	0.625
LIG_SUMO_SIM_par_1	287	292	PF11976	0.654
LIG_SUMO_SIM_par_1	33	40	PF11976	0.812
MOD_CDK_SPK_2	175	180	PF00069	0.820
MOD_CK1_1	147	153	PF00069	0.852
MOD_CK1_1	157	163	PF00069	0.661
MOD_CK1_1	182	188	PF00069	0.826
MOD_CK1_1	194	200	PF00069	0.630
MOD_CK1_1	40	46	PF00069	0.800
MOD_CK1_1	60	66	PF00069	0.446
MOD_CK2_1	224	230	PF00069	0.663
MOD_CK2_1	300	306	PF00069	0.644
MOD_GlcNHglycan	149	152	PF01048	0.851
MOD_GlcNHglycan	261	264	PF01048	0.663
MOD_GlcNHglycan	300	303	PF01048	0.651
MOD_GlcNHglycan	44	47	PF01048	0.807
MOD_GlcNHglycan	59	62	PF01048	0.536
MOD_GlcNHglycan	95	98	PF01048	0.766
MOD_GSK3_1	13	20	PF00069	0.798
MOD_GSK3_1	147	154	PF00069	0.853
MOD_GSK3_1	175	182	PF00069	0.815
MOD_GSK3_1	191	198	PF00069	0.562
MOD_GSK3_1	200	207	PF00069	0.702
MOD_GSK3_1	294	301	PF00069	0.672
MOD_GSK3_1	321	328	PF00069	0.653
MOD_GSK3_1	332	339	PF00069	0.567
MOD_GSK3_1	36	43	PF00069	0.804
MOD_N-GLC_1	173	178	PF02516	0.823
MOD_N-GLC_2	19	21	PF02516	0.805
MOD_NEK2_1	112	117	PF00069	0.763
MOD_NEK2_1	6	11	PF00069	0.779
MOD_NEK2_2	105	110	PF00069	0.743
MOD_OFUCOSY	14	21	PF10250	0.800
MOD_OFUCOSY	334	340	PF10250	0.759
MOD_PKA_1	144	150	PF00069	0.859
MOD_PKA_2	144	150	PF00069	0.859
MOD_PKA_2	154	160	PF00069	0.668
MOD_PKA_2	179	185	PF00069	0.817
MOD_PKA_2	265	271	PF00069	0.644
MOD_PKA_2	6	12	PF00069	0.780
MOD_PKB_1	142	150	PF00069	0.855
MOD_Plk_1	173	179	PF00069	0.821
MOD_Plk_1	266	272	PF00069	0.646
MOD_Plk_1	325	331	PF00069	0.718
MOD_Plk_4	13	19	PF00069	0.797
MOD_Plk_4	182	188	PF00069	0.826
MOD_ProDKin_1	175	181	PF00069	0.815
MOD_ProDKin_1	191	197	PF00069	0.561
MOD_ProDKin_1	204	210	PF00069	0.637
MOD_ProDKin_1	224	230	PF00069	0.313
MOD_ProDKin_1	296	302	PF00069	0.668
MOD_ProDKin_1	332	338	PF00069	0.759
MOD_ProDKin_1	37	43	PF00069	0.800
TRG_DiLeu_BaLyEn_6	31	36	PF01217	0.812
TRG_ENDOCYTIC_2	99	102	PF00928	0.759
TRG_ER_diArg_1	142	145	PF00400	0.850
TRG_ER_diArg_1	78	81	PF00400	0.775
TRG_NLS_MonoExtC_3	77	82	PF00514	0.774
TRG_NLS_MonoExtN_4	75	82	PF00514	0.771