RNA-binding protein 5-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA-binding protein 5-like protein

Species:

Leishmania mexicana

UniProt:

E9AMK9_LEIMU

TriTrypDb:

LmxM.09.0080

Length:

245

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1
GO:1990904	ribonucleoprotein complex	2	1

Expansion

Sequence features

E9AMK9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMK9

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003723	RNA binding	4	7
GO:0005488	binding	1	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	132	136	PF00656	0.573
CLV_NRD_NRD_1	94	96	PF00675	0.548
CLV_PCSK_KEX2_1	94	96	PF00082	0.533
CLV_PCSK_PC7_1	90	96	PF00082	0.430
DEG_SPOP_SBC_1	159	163	PF00917	0.432
DOC_CKS1_1	108	113	PF01111	0.648
DOC_CYCLIN_yCln2_LP_2	108	114	PF00134	0.644
DOC_USP7_MATH_1	157	161	PF00917	0.548
DOC_USP7_MATH_1	54	58	PF00917	0.469
DOC_USP7_MATH_1	98	102	PF00917	0.563
DOC_WW_Pin1_4	107	112	PF00397	0.782
DOC_WW_Pin1_4	114	119	PF00397	0.694
DOC_WW_Pin1_4	175	180	PF00397	0.633
DOC_WW_Pin1_4	38	43	PF00397	0.495
LIG_14-3-3_CanoR_1	45	52	PF00244	0.471
LIG_14-3-3_CanoR_1	53	63	PF00244	0.469
LIG_Actin_WH2_2	4	19	PF00022	0.445
LIG_APCC_ABBA_1	65	70	PF00400	0.504
LIG_BRCT_BRCA1_1	100	104	PF00533	0.544
LIG_BRCT_BRCA1_2	100	106	PF00533	0.618
LIG_FHA_1	124	130	PF00498	0.585
LIG_FHA_2	130	136	PF00498	0.577
LIG_LIR_Gen_1	101	112	PF02991	0.564
LIG_LIR_Gen_1	161	172	PF02991	0.563
LIG_LIR_Nem_3	101	107	PF02991	0.551
LIG_LIR_Nem_3	161	167	PF02991	0.550
LIG_LIR_Nem_3	185	189	PF02991	0.632
LIG_LIR_Nem_3	38	43	PF02991	0.482
LIG_LIR_Nem_3	60	66	PF02991	0.489
LIG_MAD2	106	114	PF02301	0.641
LIG_PTB_Apo_2	180	187	PF02174	0.593
LIG_PTB_Phospho_1	180	186	PF10480	0.593
LIG_SH2_CRK	164	168	PF00017	0.567
LIG_SH2_CRK	186	190	PF00017	0.565
LIG_SH2_CRK	43	47	PF00017	0.469
LIG_SH2_CRK	63	67	PF00017	0.469
LIG_SH2_NCK_1	131	135	PF00017	0.571
LIG_SH2_NCK_1	164	168	PF00017	0.632
LIG_SH2_PTP2	227	230	PF00017	0.561
LIG_SH2_SRC	164	167	PF00017	0.633
LIG_SH2_STAP1	143	147	PF00017	0.607
LIG_SH2_STAP1	164	168	PF00017	0.559
LIG_SH2_STAT3	155	158	PF00017	0.543
LIG_SH2_STAT5	131	134	PF00017	0.616
LIG_SH2_STAT5	206	209	PF00017	0.549
LIG_SH2_STAT5	227	230	PF00017	0.625
LIG_SH2_STAT5	23	26	PF00017	0.504
LIG_SH3_1	131	137	PF00018	0.516
LIG_SH3_3	108	114	PF00018	0.644
LIG_SH3_3	131	137	PF00018	0.571
LIG_SH3_3	226	232	PF00018	0.674
MOD_CDK_SPxxK_3	38	45	PF00069	0.469
MOD_CK1_1	116	122	PF00069	0.660
MOD_CK1_1	124	130	PF00069	0.537
MOD_CK1_1	160	166	PF00069	0.558
MOD_CK1_1	57	63	PF00069	0.469
MOD_CK2_1	69	75	PF00069	0.516
MOD_GlcNHglycan	123	126	PF01048	0.529
MOD_GlcNHglycan	143	146	PF01048	0.564
MOD_GlcNHglycan	202	205	PF01048	0.527
MOD_GlcNHglycan	47	50	PF01048	0.296
MOD_GlcNHglycan	72	75	PF01048	0.284
MOD_GSK3_1	113	120	PF00069	0.765
MOD_GSK3_1	12	19	PF00069	0.543
MOD_GSK3_1	178	185	PF00069	0.649
MOD_GSK3_1	23	30	PF00069	0.537
MOD_GSK3_1	98	105	PF00069	0.567
MOD_NEK2_1	102	107	PF00069	0.619
MOD_NEK2_1	129	134	PF00069	0.693
MOD_NEK2_1	16	21	PF00069	0.597
MOD_PIKK_1	117	123	PF00454	0.655
MOD_Plk_1	12	18	PF00069	0.590
MOD_Plk_1	98	104	PF00069	0.615
MOD_Plk_4	124	130	PF00069	0.640
MOD_ProDKin_1	107	113	PF00069	0.784
MOD_ProDKin_1	114	120	PF00069	0.692
MOD_ProDKin_1	175	181	PF00069	0.632
MOD_ProDKin_1	38	44	PF00069	0.495
TRG_ENDOCYTIC_2	164	167	PF00928	0.568
TRG_ENDOCYTIC_2	186	189	PF00928	0.614
TRG_ENDOCYTIC_2	227	230	PF00928	0.640
TRG_ENDOCYTIC_2	43	46	PF00928	0.469
TRG_ENDOCYTIC_2	63	66	PF00928	0.469
TRG_ER_diArg_1	93	95	PF00400	0.527

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P379	Leptomonas seymouri	45%	100%
A0A3S5H6A8	Leishmania donovani	91%	100%
A4H5I5	Leishmania braziliensis	82%	100%
A4HTS6	Leishmania infantum	91%	100%
Q4QI27	Leishmania major	91%	100%