LeishMANIAdb
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PKcGMP_CC domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
PKcGMP_CC domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AMK0_LEIMU
TriTrypDb:
LmxM.09.0003
Length:
144

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 4
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMK0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMK0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 80 84 PF00656 0.594
CLV_NRD_NRD_1 116 118 PF00675 0.464
CLV_NRD_NRD_1 42 44 PF00675 0.463
CLV_NRD_NRD_1 56 58 PF00675 0.370
CLV_PCSK_KEX2_1 106 108 PF00082 0.498
CLV_PCSK_KEX2_1 116 118 PF00082 0.369
CLV_PCSK_KEX2_1 30 32 PF00082 0.519
CLV_PCSK_KEX2_1 42 44 PF00082 0.321
CLV_PCSK_KEX2_1 56 58 PF00082 0.370
CLV_PCSK_PC1ET2_1 106 108 PF00082 0.453
CLV_PCSK_PC1ET2_1 30 32 PF00082 0.519
CLV_PCSK_PC7_1 102 108 PF00082 0.495
CLV_PCSK_SKI1_1 119 123 PF00082 0.485
CLV_PCSK_SKI1_1 59 63 PF00082 0.486
DEG_Nend_UBRbox_2 1 3 PF02207 0.625
DOC_CYCLIN_RxL_1 116 125 PF00134 0.485
DOC_MAPK_gen_1 106 114 PF00069 0.485
DOC_MAPK_gen_1 116 122 PF00069 0.367
LIG_Actin_WH2_2 41 58 PF00022 0.524
LIG_FHA_2 78 84 PF00498 0.633
LIG_PCNA_yPIPBox_3 102 115 PF02747 0.503
LIG_UBA3_1 111 119 PF00899 0.483
MOD_CK1_1 5 11 PF00069 0.669
MOD_GlcNHglycan 10 13 PF01048 0.604
MOD_GlcNHglycan 123 127 PF01048 0.480
MOD_GlcNHglycan 69 72 PF01048 0.490
MOD_GlcNHglycan 91 94 PF01048 0.545
MOD_GSK3_1 2 9 PF00069 0.740
MOD_N-GLC_1 128 133 PF02516 0.450
MOD_NEK2_1 122 127 PF00069 0.537
MOD_NEK2_1 67 72 PF00069 0.463
MOD_Plk_1 128 134 PF00069 0.448
TRG_ER_diArg_1 115 117 PF00400 0.464
TRG_ER_diArg_1 41 43 PF00400 0.418
TRG_ER_diArg_1 55 57 PF00400 0.414
TRG_Pf-PMV_PEXEL_1 119 123 PF00026 0.485
TRG_Pf-PMV_PEXEL_1 22 26 PF00026 0.515

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WQF4 Leishmania donovani 73% 100%
A4H5H6 Leishmania braziliensis 60% 100%
A4HTR7 Leishmania infantum 74% 100%
Q4QI36 Leishmania major 75% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS