LeishMANIAdb
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Protein kinase domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase domain-containing protein
Gene product:
STE group serine/threonine-protein kinase, putative
Species:
Leishmania mexicana
UniProt:
E9AMJ7_LEIMU
TriTrypDb:
LmxM.08.1228
Length:
845

Annotations

LeishMANIAdb annotations

A protein kinase likely belonging to the STE20 kinase family. The TM segments are a kinetoplastid innovation, but the kinase is otherwise conservative.

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9

Expansion

Sequence features

E9AMJ7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMJ7

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 10
GO:0006793 phosphorus metabolic process 3 10
GO:0006796 phosphate-containing compound metabolic process 4 10
GO:0006807 nitrogen compound metabolic process 2 10
GO:0008152 metabolic process 1 10
GO:0009987 cellular process 1 10
GO:0016310 phosphorylation 5 10
GO:0019538 protein metabolic process 3 10
GO:0036211 protein modification process 4 10
GO:0043170 macromolecule metabolic process 3 10
GO:0043412 macromolecule modification 4 10
GO:0044237 cellular metabolic process 2 10
GO:0044238 primary metabolic process 2 10
GO:0071704 organic substance metabolic process 2 10
GO:1901564 organonitrogen compound metabolic process 3 10
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006163 purine nucleotide metabolic process 5 1
GO:0006164 purine nucleotide biosynthetic process 6 1
GO:0006171 cAMP biosynthetic process 8 1
GO:0006182 cGMP biosynthetic process 8 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006753 nucleoside phosphate metabolic process 4 1
GO:0009058 biosynthetic process 2 1
GO:0009117 nucleotide metabolic process 5 1
GO:0009150 purine ribonucleotide metabolic process 6 1
GO:0009152 purine ribonucleotide biosynthetic process 7 1
GO:0009165 nucleotide biosynthetic process 6 1
GO:0009187 cyclic nucleotide metabolic process 6 1
GO:0009190 cyclic nucleotide biosynthetic process 7 1
GO:0009259 ribonucleotide metabolic process 5 1
GO:0009260 ribonucleotide biosynthetic process 6 1
GO:0018130 heterocycle biosynthetic process 4 1
GO:0019438 aromatic compound biosynthetic process 4 1
GO:0019637 organophosphate metabolic process 3 1
GO:0019693 ribose phosphate metabolic process 4 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0034654 nucleobase-containing compound biosynthetic process 4 1
GO:0044249 cellular biosynthetic process 3 1
GO:0044271 cellular nitrogen compound biosynthetic process 4 1
GO:0044281 small molecule metabolic process 2 1
GO:0046058 cAMP metabolic process 7 1
GO:0046068 cGMP metabolic process 7 1
GO:0046390 ribose phosphate biosynthetic process 5 1
GO:0046483 heterocycle metabolic process 3 1
GO:0052652 cyclic purine nucleotide metabolic process 6 1
GO:0055086 nucleobase-containing small molecule metabolic process 3 1
GO:0072521 purine-containing compound metabolic process 4 1
GO:0072522 purine-containing compound biosynthetic process 5 1
GO:0090407 organophosphate biosynthetic process 4 1
GO:1901135 carbohydrate derivative metabolic process 3 1
GO:1901137 carbohydrate derivative biosynthetic process 4 1
GO:1901293 nucleoside phosphate biosynthetic process 5 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:1901362 organic cyclic compound biosynthetic process 4 1
GO:1901566 organonitrogen compound biosynthetic process 4 1
GO:1901576 organic substance biosynthetic process 3 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 10
GO:0003824 catalytic activity 1 10
GO:0004672 protein kinase activity 3 10
GO:0005488 binding 1 10
GO:0005524 ATP binding 5 10
GO:0016301 kinase activity 4 10
GO:0016740 transferase activity 2 10
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 10
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 10
GO:0017076 purine nucleotide binding 4 10
GO:0030554 adenyl nucleotide binding 5 10
GO:0032553 ribonucleotide binding 3 10
GO:0032555 purine ribonucleotide binding 4 10
GO:0032559 adenyl ribonucleotide binding 5 10
GO:0035639 purine ribonucleoside triphosphate binding 4 10
GO:0036094 small molecule binding 2 10
GO:0043167 ion binding 2 10
GO:0043168 anion binding 3 10
GO:0097159 organic cyclic compound binding 2 10
GO:0097367 carbohydrate derivative binding 2 10
GO:0140096 catalytic activity, acting on a protein 2 10
GO:1901265 nucleoside phosphate binding 3 10
GO:1901363 heterocyclic compound binding 2 10
GO:0004674 protein serine/threonine kinase activity 4 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 118 120 PF00675 0.519
CLV_NRD_NRD_1 299 301 PF00675 0.480
CLV_NRD_NRD_1 384 386 PF00675 0.570
CLV_NRD_NRD_1 474 476 PF00675 0.613
CLV_NRD_NRD_1 606 608 PF00675 0.322
CLV_NRD_NRD_1 727 729 PF00675 0.358
CLV_NRD_NRD_1 821 823 PF00675 0.359
CLV_PCSK_FUR_1 604 608 PF00082 0.327
CLV_PCSK_KEX2_1 118 120 PF00082 0.519
CLV_PCSK_KEX2_1 298 300 PF00082 0.442
CLV_PCSK_KEX2_1 384 386 PF00082 0.570
CLV_PCSK_KEX2_1 474 476 PF00082 0.625
CLV_PCSK_KEX2_1 604 606 PF00082 0.324
CLV_PCSK_KEX2_1 727 729 PF00082 0.358
CLV_PCSK_KEX2_1 821 823 PF00082 0.359
CLV_PCSK_PC1ET2_1 298 300 PF00082 0.482
CLV_PCSK_PC1ET2_1 821 823 PF00082 0.358
CLV_PCSK_SKI1_1 191 195 PF00082 0.593
CLV_PCSK_SKI1_1 352 356 PF00082 0.528
CLV_PCSK_SKI1_1 411 415 PF00082 0.523
CLV_PCSK_SKI1_1 591 595 PF00082 0.394
CLV_PCSK_SKI1_1 727 731 PF00082 0.358
CLV_PCSK_SKI1_1 805 809 PF00082 0.325
CLV_PCSK_SKI1_1 823 827 PF00082 0.305
CLV_Separin_Metazoa 314 318 PF03568 0.751
DEG_Nend_UBRbox_1 1 4 PF02207 0.816
DEG_SCF_FBW7_1 547 553 PF00400 0.709
DEG_SPOP_SBC_1 446 450 PF00917 0.791
DEG_SPOP_SBC_1 838 842 PF00917 0.701
DOC_ANK_TNKS_1 685 692 PF00023 0.606
DOC_CDC14_PxL_1 423 431 PF14671 0.695
DOC_CDC14_PxL_1 45 53 PF14671 0.498
DOC_CKS1_1 440 445 PF01111 0.762
DOC_CKS1_1 547 552 PF01111 0.718
DOC_CKS1_1 799 804 PF01111 0.558
DOC_CYCLIN_yCln2_LP_2 538 544 PF00134 0.695
DOC_MAPK_gen_1 298 307 PF00069 0.640
DOC_MAPK_gen_1 340 348 PF00069 0.689
DOC_MAPK_gen_1 605 616 PF00069 0.499
DOC_MAPK_gen_1 804 812 PF00069 0.554
DOC_MAPK_HePTP_8 297 309 PF00069 0.680
DOC_MAPK_MEF2A_6 298 306 PF00069 0.642
DOC_MAPK_MEF2A_6 573 581 PF00069 0.561
DOC_MAPK_MEF2A_6 804 812 PF00069 0.594
DOC_MAPK_MEF2A_6 95 103 PF00069 0.361
DOC_PP2B_LxvP_1 46 49 PF13499 0.498
DOC_PP2B_LxvP_1 829 832 PF13499 0.558
DOC_PP4_FxxP_1 239 242 PF00568 0.816
DOC_USP7_MATH_1 196 200 PF00917 0.822
DOC_USP7_MATH_1 446 450 PF00917 0.791
DOC_USP7_MATH_1 531 535 PF00917 0.769
DOC_USP7_MATH_1 668 672 PF00917 0.565
DOC_USP7_MATH_1 838 842 PF00917 0.724
DOC_USP7_MATH_1 84 88 PF00917 0.541
DOC_USP7_UBL2_3 826 830 PF12436 0.596
DOC_WW_Pin1_4 11 16 PF00397 0.766
DOC_WW_Pin1_4 202 207 PF00397 0.829
DOC_WW_Pin1_4 217 222 PF00397 0.643
DOC_WW_Pin1_4 245 250 PF00397 0.766
DOC_WW_Pin1_4 384 389 PF00397 0.726
DOC_WW_Pin1_4 439 444 PF00397 0.711
DOC_WW_Pin1_4 447 452 PF00397 0.748
DOC_WW_Pin1_4 473 478 PF00397 0.601
DOC_WW_Pin1_4 532 537 PF00397 0.638
DOC_WW_Pin1_4 540 545 PF00397 0.691
DOC_WW_Pin1_4 546 551 PF00397 0.591
DOC_WW_Pin1_4 737 742 PF00397 0.519
DOC_WW_Pin1_4 798 803 PF00397 0.558
LIG_14-3-3_CanoR_1 277 283 PF00244 0.821
LIG_14-3-3_CanoR_1 352 358 PF00244 0.683
LIG_14-3-3_CanoR_1 36 46 PF00244 0.742
LIG_14-3-3_CanoR_1 499 506 PF00244 0.607
LIG_14-3-3_CanoR_1 578 588 PF00244 0.558
LIG_14-3-3_CanoR_1 633 643 PF00244 0.606
LIG_14-3-3_CanoR_1 727 737 PF00244 0.558
LIG_14-3-3_CanoR_1 74 79 PF00244 0.534
LIG_14-3-3_CanoR_1 822 829 PF00244 0.558
LIG_14-3-3_CanoR_1 95 99 PF00244 0.406
LIG_Actin_WH2_2 639 655 PF00022 0.618
LIG_AP2alpha_1 378 382 PF02296 0.758
LIG_APCC_ABBA_1 346 351 PF00400 0.697
LIG_APCC_ABBAyCdc20_2 698 704 PF00400 0.596
LIG_BRCT_BRCA1_1 146 150 PF00533 0.747
LIG_BRCT_BRCA1_1 278 282 PF00533 0.782
LIG_BRCT_BRCA1_1 326 330 PF00533 0.683
LIG_BRCT_BRCA1_1 533 537 PF00533 0.763
LIG_CSL_BTD_1 246 249 PF09270 0.810
LIG_deltaCOP1_diTrp_1 758 762 PF00928 0.519
LIG_EH1_1 55 63 PF00400 0.440
LIG_FHA_1 187 193 PF00498 0.770
LIG_FHA_1 39 45 PF00498 0.656
LIG_FHA_1 398 404 PF00498 0.722
LIG_FHA_1 518 524 PF00498 0.789
LIG_FHA_1 52 58 PF00498 0.363
LIG_FHA_1 635 641 PF00498 0.561
LIG_FHA_1 728 734 PF00498 0.567
LIG_FHA_1 769 775 PF00498 0.596
LIG_FHA_2 309 315 PF00498 0.705
LIG_FHA_2 405 411 PF00498 0.728
LIG_FHA_2 426 432 PF00498 0.729
LIG_FHA_2 474 480 PF00498 0.807
LIG_FHA_2 492 498 PF00498 0.736
LIG_FHA_2 547 553 PF00498 0.713
LIG_FHA_2 615 621 PF00498 0.565
LIG_FHA_2 747 753 PF00498 0.623
LIG_FHA_2 813 819 PF00498 0.559
LIG_FHA_2 822 828 PF00498 0.498
LIG_GBD_Chelix_1 302 310 PF00786 0.528
LIG_Integrin_RGD_1 597 599 PF01839 0.406
LIG_IRF3_LxIS_1 106 113 PF10401 0.440
LIG_IRF3_LxIS_1 576 582 PF10401 0.606
LIG_LIR_Apic_2 740 746 PF02991 0.519
LIG_LIR_Gen_1 111 121 PF02991 0.362
LIG_LIR_Gen_1 356 364 PF02991 0.704
LIG_LIR_Gen_1 42 51 PF02991 0.571
LIG_LIR_Gen_1 453 462 PF02991 0.764
LIG_LIR_Gen_1 549 555 PF02991 0.673
LIG_LIR_Gen_1 584 595 PF02991 0.614
LIG_LIR_Gen_1 70 79 PF02991 0.483
LIG_LIR_Gen_1 97 108 PF02991 0.398
LIG_LIR_Nem_3 111 117 PF02991 0.362
LIG_LIR_Nem_3 147 152 PF02991 0.719
LIG_LIR_Nem_3 171 175 PF02991 0.647
LIG_LIR_Nem_3 308 312 PF02991 0.639
LIG_LIR_Nem_3 356 360 PF02991 0.623
LIG_LIR_Nem_3 42 48 PF02991 0.571
LIG_LIR_Nem_3 431 437 PF02991 0.697
LIG_LIR_Nem_3 453 457 PF02991 0.769
LIG_LIR_Nem_3 549 554 PF02991 0.699
LIG_LIR_Nem_3 584 590 PF02991 0.606
LIG_LIR_Nem_3 70 75 PF02991 0.491
LIG_LIR_Nem_3 782 786 PF02991 0.596
LIG_LIR_Nem_3 97 103 PF02991 0.398
LIG_MLH1_MIPbox_1 146 150 PF16413 0.718
LIG_PCNA_TLS_4 805 812 PF02747 0.596
LIG_PDZ_Class_3 840 845 PF00595 0.778
LIG_Pex14_1 168 172 PF04695 0.693
LIG_Pex14_1 357 361 PF04695 0.737
LIG_Pex14_2 378 382 PF04695 0.734
LIG_SH2_CRK 96 100 PF00017 0.498
LIG_SH2_GRB2like 63 66 PF00017 0.573
LIG_SH2_PTP2 437 440 PF00017 0.698
LIG_SH2_PTP2 63 66 PF00017 0.573
LIG_SH2_SRC 24 27 PF00017 0.770
LIG_SH2_SRC 63 66 PF00017 0.573
LIG_SH2_SRC 776 779 PF00017 0.427
LIG_SH2_SRC 817 820 PF00017 0.547
LIG_SH2_STAP1 349 353 PF00017 0.744
LIG_SH2_STAP1 551 555 PF00017 0.693
LIG_SH2_STAP1 96 100 PF00017 0.480
LIG_SH2_STAT5 393 396 PF00017 0.747
LIG_SH2_STAT5 399 402 PF00017 0.730
LIG_SH2_STAT5 434 437 PF00017 0.701
LIG_SH2_STAT5 63 66 PF00017 0.554
LIG_SH2_STAT5 642 645 PF00017 0.522
LIG_SH2_STAT5 658 661 PF00017 0.522
LIG_SH2_STAT5 784 787 PF00017 0.558
LIG_SH2_STAT5 833 836 PF00017 0.587
LIG_SH2_STAT5 96 99 PF00017 0.412
LIG_SH3_1 474 480 PF00018 0.599
LIG_SH3_3 200 206 PF00018 0.628
LIG_SH3_3 474 480 PF00018 0.640
LIG_SH3_3 519 525 PF00018 0.785
LIG_SH3_3 530 536 PF00018 0.796
LIG_SH3_3 538 544 PF00018 0.746
LIG_SH3_3 707 713 PF00018 0.558
LIG_SH3_3 73 79 PF00018 0.492
LIG_SH3_3 772 778 PF00018 0.427
LIG_SUMO_SIM_anti_2 102 107 PF11976 0.492
LIG_SUMO_SIM_anti_2 627 632 PF11976 0.561
LIG_SUMO_SIM_par_1 130 135 PF11976 0.731
LIG_SUMO_SIM_par_1 303 308 PF11976 0.687
LIG_SUMO_SIM_par_1 344 351 PF11976 0.715
LIG_TYR_ITIM 310 315 PF00017 0.563
LIG_TYR_ITIM 61 66 PF00017 0.570
LIG_WRC_WIRS_1 306 311 PF05994 0.680
LIG_WRC_WIRS_1 551 556 PF05994 0.546
LIG_WRC_WIRS_1 642 647 PF05994 0.434
LIG_WRC_WIRS_1 66 71 PF05994 0.544
LIG_WRC_WIRS_1 759 764 PF05994 0.376
MOD_CDK_SPK_2 540 545 PF00069 0.488
MOD_CDK_SPxK_1 798 804 PF00069 0.425
MOD_CDK_SPxxK_3 798 805 PF00069 0.484
MOD_CK1_1 216 222 PF00069 0.743
MOD_CK1_1 253 259 PF00069 0.815
MOD_CK1_1 276 282 PF00069 0.682
MOD_CK1_1 308 314 PF00069 0.609
MOD_CK1_1 37 43 PF00069 0.645
MOD_CK1_1 387 393 PF00069 0.716
MOD_CK1_1 450 456 PF00069 0.774
MOD_CK1_1 540 546 PF00069 0.622
MOD_CK1_1 70 76 PF00069 0.500
MOD_CK2_1 127 133 PF00069 0.670
MOD_CK2_1 19 25 PF00069 0.614
MOD_CK2_1 308 314 PF00069 0.593
MOD_CK2_1 404 410 PF00069 0.610
MOD_CK2_1 425 431 PF00069 0.560
MOD_CK2_1 473 479 PF00069 0.783
MOD_CK2_1 491 497 PF00069 0.491
MOD_CK2_1 546 552 PF00069 0.661
MOD_CK2_1 614 620 PF00069 0.440
MOD_CK2_1 641 647 PF00069 0.434
MOD_CK2_1 732 738 PF00069 0.484
MOD_CK2_1 746 752 PF00069 0.254
MOD_CK2_1 821 827 PF00069 0.286
MOD_CK2_1 837 843 PF00069 0.636
MOD_DYRK1A_RPxSP_1 202 206 PF00069 0.529
MOD_GlcNHglycan 171 175 PF01048 0.651
MOD_GlcNHglycan 198 201 PF01048 0.770
MOD_GlcNHglycan 215 218 PF01048 0.468
MOD_GlcNHglycan 257 260 PF01048 0.818
MOD_GlcNHglycan 273 276 PF01048 0.827
MOD_GlcNHglycan 362 365 PF01048 0.589
MOD_GlcNHglycan 389 392 PF01048 0.621
MOD_GlcNHglycan 501 504 PF01048 0.554
MOD_GlcNHglycan 714 717 PF01048 0.431
MOD_GlcNHglycan 734 737 PF01048 0.434
MOD_GSK3_1 140 147 PF00069 0.631
MOD_GSK3_1 202 209 PF00069 0.778
MOD_GSK3_1 211 218 PF00069 0.695
MOD_GSK3_1 25 32 PF00069 0.702
MOD_GSK3_1 276 283 PF00069 0.741
MOD_GSK3_1 34 41 PF00069 0.618
MOD_GSK3_1 393 400 PF00069 0.679
MOD_GSK3_1 405 412 PF00069 0.613
MOD_GSK3_1 446 453 PF00069 0.703
MOD_GSK3_1 532 539 PF00069 0.688
MOD_GSK3_1 546 553 PF00069 0.600
MOD_GSK3_1 70 77 PF00069 0.573
MOD_GSK3_1 723 730 PF00069 0.387
MOD_GSK3_1 742 749 PF00069 0.191
MOD_N-GLC_2 335 337 PF02516 0.654
MOD_NEK2_1 1 6 PF00069 0.495
MOD_NEK2_1 110 115 PF00069 0.348
MOD_NEK2_1 293 298 PF00069 0.696
MOD_NEK2_1 305 310 PF00069 0.607
MOD_NEK2_1 360 365 PF00069 0.678
MOD_NEK2_1 452 457 PF00069 0.772
MOD_NEK2_1 51 56 PF00069 0.456
MOD_NEK2_1 564 569 PF00069 0.526
MOD_NEK2_1 667 672 PF00069 0.509
MOD_NEK2_1 723 728 PF00069 0.403
MOD_NEK2_1 812 817 PF00069 0.394
MOD_NEK2_1 99 104 PF00069 0.398
MOD_NEK2_2 550 555 PF00069 0.570
MOD_PIKK_1 206 212 PF00454 0.760
MOD_PIKK_1 784 790 PF00454 0.431
MOD_PIKK_1 812 818 PF00454 0.394
MOD_PKA_1 727 733 PF00069 0.431
MOD_PKA_1 821 827 PF00069 0.431
MOD_PKA_2 1 7 PF00069 0.495
MOD_PKA_2 161 167 PF00069 0.641
MOD_PKA_2 194 200 PF00069 0.738
MOD_PKA_2 276 282 PF00069 0.746
MOD_PKA_2 35 41 PF00069 0.710
MOD_PKA_2 634 640 PF00069 0.498
MOD_PKA_2 727 733 PF00069 0.431
MOD_PKA_2 821 827 PF00069 0.376
MOD_PKA_2 94 100 PF00069 0.486
MOD_Plk_1 132 138 PF00069 0.569
MOD_Plk_1 293 299 PF00069 0.654
MOD_Plk_1 409 415 PF00069 0.646
MOD_Plk_1 84 90 PF00069 0.628
MOD_Plk_2-3 19 25 PF00069 0.731
MOD_Plk_4 127 133 PF00069 0.681
MOD_Plk_4 145 151 PF00069 0.733
MOD_Plk_4 19 25 PF00069 0.731
MOD_Plk_4 305 311 PF00069 0.567
MOD_Plk_4 409 415 PF00069 0.633
MOD_Plk_4 418 424 PF00069 0.593
MOD_Plk_4 425 431 PF00069 0.468
MOD_Plk_4 51 57 PF00069 0.401
MOD_Plk_4 550 556 PF00069 0.547
MOD_Plk_4 564 570 PF00069 0.434
MOD_Plk_4 94 100 PF00069 0.427
MOD_ProDKin_1 11 17 PF00069 0.721
MOD_ProDKin_1 202 208 PF00069 0.810
MOD_ProDKin_1 217 223 PF00069 0.552
MOD_ProDKin_1 245 251 PF00069 0.723
MOD_ProDKin_1 384 390 PF00069 0.665
MOD_ProDKin_1 439 445 PF00069 0.651
MOD_ProDKin_1 447 453 PF00069 0.697
MOD_ProDKin_1 473 479 PF00069 0.492
MOD_ProDKin_1 532 538 PF00069 0.544
MOD_ProDKin_1 540 546 PF00069 0.613
MOD_ProDKin_1 737 743 PF00069 0.376
MOD_ProDKin_1 798 804 PF00069 0.431
MOD_SUMO_for_1 593 596 PF00179 0.440
MOD_SUMO_rev_2 565 574 PF00179 0.434
MOD_SUMO_rev_2 596 603 PF00179 0.498
MOD_SUMO_rev_2 644 652 PF00179 0.440
TRG_DiLeu_BaEn_1 410 415 PF01217 0.704
TRG_DiLeu_BaEn_2 582 588 PF01217 0.498
TRG_DiLeu_BaEn_2 689 695 PF01217 0.431
TRG_ENDOCYTIC_2 121 124 PF00928 0.575
TRG_ENDOCYTIC_2 312 315 PF00928 0.558
TRG_ENDOCYTIC_2 437 440 PF00928 0.626
TRG_ENDOCYTIC_2 551 554 PF00928 0.619
TRG_ENDOCYTIC_2 63 66 PF00928 0.554
TRG_ENDOCYTIC_2 642 645 PF00928 0.434
TRG_ENDOCYTIC_2 783 786 PF00928 0.484
TRG_ENDOCYTIC_2 96 99 PF00928 0.412
TRG_ER_diArg_1 117 119 PF00400 0.653
TRG_ER_diArg_1 383 385 PF00400 0.713
TRG_ER_diArg_1 473 475 PF00400 0.791
TRG_ER_diArg_1 603 606 PF00400 0.354
TRG_NES_CRM1_1 128 139 PF08389 0.672
TRG_NLS_Bipartite_1 804 825 PF00514 0.425
TRG_NLS_MonoExtN_4 819 825 PF00514 0.425

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P5H9 Leptomonas seymouri 49% 97%
A0A3S5H699 Leishmania donovani 93% 85%
A0A3S7WQE5 Leishmania donovani 93% 99%
A4HC47 Leishmania braziliensis 83% 99%
E9AG93 Leishmania infantum 93% 99%
Q4QI37 Leishmania major 92% 100%
Q4QI43 Leishmania major 92% 100%
V5BPV2 Trypanosoma cruzi 27% 87%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS