Phosphoribosylpyrophosphate synthetase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

phosphoribosylpyrophosphate synthetase

Species:

Leishmania mexicana

UniProt:

E9AMI3_LEIMU

TriTrypDb:

LmxM.08.1130

Length:

371

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 75

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 33
NetGPI	no	yes: 0, no: 33

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	4
GO:0002189	ribose phosphate diphosphokinase complex	5	3
GO:0005737	cytoplasm	2	3
GO:0032991	protein-containing complex	1	3
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	3
GO:1902494	catalytic complex	2	3
GO:1990234	transferase complex	3	3

Expansion

Sequence features

E9AMI3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMI3

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	34
GO:0006725	cellular aromatic compound metabolic process	3	34
GO:0006753	nucleoside phosphate metabolic process	4	34
GO:0006793	phosphorus metabolic process	3	34
GO:0006796	phosphate-containing compound metabolic process	4	34
GO:0006807	nitrogen compound metabolic process	2	34
GO:0008152	metabolic process	1	34
GO:0009058	biosynthetic process	2	34
GO:0009117	nucleotide metabolic process	5	34
GO:0009165	nucleotide biosynthetic process	6	34
GO:0009987	cellular process	1	34
GO:0018130	heterocycle biosynthetic process	4	34
GO:0019438	aromatic compound biosynthetic process	4	34
GO:0019637	organophosphate metabolic process	3	34
GO:0034641	cellular nitrogen compound metabolic process	3	34
GO:0034654	nucleobase-containing compound biosynthetic process	4	34
GO:0044237	cellular metabolic process	2	34
GO:0044238	primary metabolic process	2	34
GO:0044249	cellular biosynthetic process	3	34
GO:0044271	cellular nitrogen compound biosynthetic process	4	34
GO:0044281	small molecule metabolic process	2	34
GO:0046483	heterocycle metabolic process	3	34
GO:0055086	nucleobase-containing small molecule metabolic process	3	34
GO:0071704	organic substance metabolic process	2	34
GO:0090407	organophosphate biosynthetic process	4	34
GO:1901293	nucleoside phosphate biosynthetic process	5	34
GO:1901360	organic cyclic compound metabolic process	3	34
GO:1901362	organic cyclic compound biosynthetic process	4	34
GO:1901576	organic substance biosynthetic process	3	34
GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	6	3
GO:0006163	purine nucleotide metabolic process	5	3
GO:0006164	purine nucleotide biosynthetic process	6	3
GO:0019693	ribose phosphate metabolic process	4	3
GO:0046390	ribose phosphate biosynthetic process	5	3
GO:0046391	5-phosphoribose 1-diphosphate metabolic process	5	3
GO:0072521	purine-containing compound metabolic process	4	3
GO:0072522	purine-containing compound biosynthetic process	5	3
GO:1901135	carbohydrate derivative metabolic process	3	3
GO:1901137	carbohydrate derivative biosynthetic process	4	3
GO:1901564	organonitrogen compound metabolic process	3	3
GO:1901566	organonitrogen compound biosynthetic process	4	3
GO:0016310	phosphorylation	5	3

Molecular functions
Term	Name	Level	Count
GO:0000287	magnesium ion binding	5	34
GO:0003824	catalytic activity	1	34
GO:0004749	ribose phosphate diphosphokinase activity	5	34
GO:0005488	binding	1	34
GO:0016740	transferase activity	2	34
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	34
GO:0016778	diphosphotransferase activity	4	34
GO:0043167	ion binding	2	34
GO:0043169	cation binding	3	34
GO:0046872	metal ion binding	4	34
GO:0016301	kinase activity	4	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	367	371	PF00656	0.473
CLV_NRD_NRD_1	121	123	PF00675	0.296
CLV_NRD_NRD_1	145	147	PF00675	0.294
CLV_NRD_NRD_1	245	247	PF00675	0.509
CLV_NRD_NRD_1	40	42	PF00675	0.599
CLV_PCSK_KEX2_1	11	13	PF00082	0.465
CLV_PCSK_KEX2_1	244	246	PF00082	0.466
CLV_PCSK_KEX2_1	40	42	PF00082	0.653
CLV_PCSK_PC1ET2_1	11	13	PF00082	0.465
CLV_PCSK_PC1ET2_1	244	246	PF00082	0.459
CLV_PCSK_SKI1_1	130	134	PF00082	0.276
CLV_PCSK_SKI1_1	238	242	PF00082	0.410
DOC_CYCLIN_yCln2_LP_2	150	156	PF00134	0.545
DOC_MAPK_MEF2A_6	333	340	PF00069	0.462
DOC_MAPK_RevD_3	231	246	PF00069	0.485
DOC_PIKK_1	186	193	PF02985	0.477
DOC_PP2B_LxvP_1	363	366	PF13499	0.729
DOC_PP4_FxxP_1	18	21	PF00568	0.502
DOC_USP7_UBL2_3	11	15	PF12436	0.480
DOC_USP7_UBL2_3	333	337	PF12436	0.522
DOC_WW_Pin1_4	1	6	PF00397	0.617
DOC_WW_Pin1_4	215	220	PF00397	0.419
DOC_WW_Pin1_4	302	307	PF00397	0.473
DOC_WW_Pin1_4	32	37	PF00397	0.541
LIG_14-3-3_CanoR_1	146	151	PF00244	0.495
LIG_14-3-3_CanoR_1	170	175	PF00244	0.361
LIG_Actin_WH2_2	356	371	PF00022	0.401
LIG_APCC_ABBA_1	34	39	PF00400	0.688
LIG_BIR_III_4	220	224	PF00653	0.455
LIG_BRCT_BRCA1_1	360	364	PF00533	0.479
LIG_BRCT_BRCA1_1	43	47	PF00533	0.433
LIG_CtBP_PxDLS_1	365	369	PF00389	0.455
LIG_EH1_1	208	216	PF00400	0.516
LIG_FHA_1	263	269	PF00498	0.498
LIG_FHA_1	297	303	PF00498	0.490
LIG_FHA_2	101	107	PF00498	0.520
LIG_GBD_Chelix_1	347	355	PF00786	0.234
LIG_LIR_Apic_2	42	46	PF02991	0.435
LIG_LIR_LC3C_4	318	322	PF02991	0.507
LIG_LIR_Nem_3	198	202	PF02991	0.365
LIG_LIR_Nem_3	205	211	PF02991	0.547
LIG_LIR_Nem_3	44	50	PF02991	0.610
LIG_NRBOX	113	119	PF00104	0.522
LIG_PCNA_yPIPBox_3	111	125	PF02747	0.479
LIG_PCNA_yPIPBox_3	187	201	PF02747	0.417
LIG_SH2_CRK	43	47	PF00017	0.610
LIG_SH2_GRB2like	354	357	PF00017	0.434
LIG_SH2_GRB2like	78	81	PF00017	0.580
LIG_SH2_NCK_1	43	47	PF00017	0.400
LIG_SH2_SRC	19	22	PF00017	0.698
LIG_SH2_STAT3	141	144	PF00017	0.482
LIG_SH2_STAT3	17	20	PF00017	0.672
LIG_SH2_STAT3	97	100	PF00017	0.479
LIG_SH2_STAT5	17	20	PF00017	0.676
LIG_SH2_STAT5	202	205	PF00017	0.428
LIG_SH2_STAT5	354	357	PF00017	0.437
LIG_SH2_STAT5	97	100	PF00017	0.505
LIG_SH3_3	131	137	PF00018	0.555
LIG_SH3_3	213	219	PF00018	0.421
LIG_SUMO_SIM_anti_2	116	122	PF11976	0.482
LIG_SUMO_SIM_anti_2	131	136	PF11976	0.482
LIG_SUMO_SIM_anti_2	60	66	PF11976	0.523
LIG_SUMO_SIM_par_1	106	112	PF11976	0.479
LIG_SUMO_SIM_par_1	212	218	PF11976	0.380
LIG_TRAF2_1	327	330	PF00917	0.537
LIG_UBA3_1	114	123	PF00899	0.483
MOD_CK1_1	359	365	PF00069	0.501
MOD_CK2_1	100	106	PF00069	0.516
MOD_CK2_1	254	260	PF00069	0.556
MOD_CK2_1	312	318	PF00069	0.475
MOD_CK2_1	76	82	PF00069	0.546
MOD_GlcNHglycan	154	157	PF01048	0.281
MOD_GlcNHglycan	30	33	PF01048	0.672
MOD_GlcNHglycan	314	317	PF01048	0.371
MOD_GlcNHglycan	50	53	PF01048	0.292
MOD_GSK3_1	124	131	PF00069	0.497
MOD_GSK3_1	28	35	PF00069	0.595
MOD_GSK3_1	364	371	PF00069	0.567
MOD_GSK3_1	67	74	PF00069	0.531
MOD_N-GLC_1	186	191	PF02516	0.257
MOD_N-GLC_1	312	317	PF02516	0.376
MOD_N-GLC_2	312	314	PF02516	0.284
MOD_N-GLC_2	88	90	PF02516	0.219
MOD_NEK2_1	124	129	PF00069	0.488
MOD_NEK2_1	272	277	PF00069	0.501
MOD_NEK2_1	65	70	PF00069	0.500
MOD_PIKK_1	73	79	PF00454	0.515
MOD_PKA_1	146	152	PF00069	0.506
MOD_PKA_2	124	130	PF00069	0.474
MOD_PKA_2	145	151	PF00069	0.496
MOD_Plk_1	186	192	PF00069	0.251
MOD_Plk_1	312	318	PF00069	0.550
MOD_Plk_1	356	362	PF00069	0.486
MOD_Plk_2-3	186	192	PF00069	0.251
MOD_Plk_4	130	136	PF00069	0.576
MOD_Plk_4	154	160	PF00069	0.431
MOD_Plk_4	238	244	PF00069	0.376
MOD_Plk_4	275	281	PF00069	0.522
MOD_Plk_4	336	342	PF00069	0.486
MOD_Plk_4	359	365	PF00069	0.503
MOD_ProDKin_1	1	7	PF00069	0.612
MOD_ProDKin_1	215	221	PF00069	0.432
MOD_ProDKin_1	302	308	PF00069	0.473
MOD_ProDKin_1	32	38	PF00069	0.545
TRG_DiLeu_BaEn_1	116	121	PF01217	0.479
TRG_DiLeu_BaEn_1	60	65	PF01217	0.522
TRG_DiLeu_BaLyEn_6	342	347	PF01217	0.474
TRG_ER_diArg_1	245	247	PF00400	0.492
TRG_Pf-PMV_PEXEL_1	201	205	PF00026	0.520
TRG_Pf-PMV_PEXEL_1	56	60	PF00026	0.290

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8G4	Leptomonas seymouri	57%	100%
A0A0N1I914	Leptomonas seymouri	50%	100%
A0A0N1PE41	Leptomonas seymouri	85%	100%
A0A0S4IME5	Bodo saltans	56%	100%
A0A0S4IQW2	Bodo saltans	52%	81%
A0A0S4IW81	Bodo saltans	49%	100%
A0A1X0NFA8	Trypanosomatidae	64%	95%
A0A1X0P0G5	Trypanosomatidae	50%	95%
A0A1X0P3L9	Trypanosomatidae	56%	100%
A0A3Q8IHV7	Leishmania donovani	48%	100%
A0A3R7KT84	Trypanosoma rangeli	57%	100%
A0A422NFU4	Trypanosoma rangeli	58%	87%
A0A422NKU6	Trypanosoma rangeli	50%	95%
A2VDS0	Bos taurus	33%	100%
A4H5F1	Leishmania braziliensis	91%	100%
A4HLQ5	Leishmania braziliensis	56%	100%
A4HQ54	Leishmania braziliensis	49%	100%
A4HTP6	Leishmania infantum	97%	100%
A4I955	Leishmania infantum	57%	100%
A4IDV3	Leishmania infantum	48%	100%
A5UNK4	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	29%	100%
A6W1C7	Marinomonas sp. (strain MWYL1)	43%	100%
B7IFM5	Thermosipho africanus (strain TCF52B)	42%	100%
B8GZV1	Caulobacter vibrioides (strain NA1000 / CB15N)	43%	100%
B9KPJ0	Cereibacter sphaeroides (strain KD131 / KCTC 12085)	42%	100%
C9ZPE9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	96%
D0A464	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	98%
D0A6B7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	84%
E0Z5R2	Leishmania donovani	57%	100%
E9ATX4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	48%	100%
E9B430	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	100%
O08618	Rattus norvegicus	33%	100%
O26877	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	28%	100%
O28853	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	28%	100%
O29666	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	30%	100%
O33924	Corynebacterium ammoniagenes	42%	100%
O52958	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	30%	100%
O59586	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	30%	100%
O60256	Homo sapiens	33%	100%
O64888	Arabidopsis thaliana	34%	94%
O67556	Aquifex aeolicus (strain VF5)	43%	100%
O94413	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	100%
P09330	Rattus norvegicus	42%	100%
P0A1V6	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	43%	100%
P0A1V7	Salmonella typhi	43%	100%
P0A717	Escherichia coli (strain K12)	43%	100%
P0A718	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	43%	100%
P0A719	Escherichia coli O157:H7	43%	100%
P0DB98	Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)	41%	100%
P0DB99	Streptococcus pyogenes serotype M3 (strain SSI-1)	41%	100%
P0DC00	Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)	34%	100%
P0DC01	Streptococcus pyogenes serotype M3 (strain SSI-1)	34%	100%
P11908	Homo sapiens	42%	100%
P14193	Bacillus subtilis (strain 168)	42%	100%
P21108	Homo sapiens	41%	100%
P38063	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	100%
P38620	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	100%
P38689	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	100%
P42816	Bacillus caldolyticus	43%	100%
P44328	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	42%	100%
P46585	Candida albicans	38%	100%
P47304	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	37%	100%
P56184	Helicobacter pylori (strain ATCC 700392 / 26695)	41%	100%
P57266	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	42%	100%
P59512	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	41%	100%
P60891	Homo sapiens	42%	100%
P60892	Rattus norvegicus	42%	100%
P65233	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	38%	100%
P65234	Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)	42%	100%
P65235	Neisseria meningitidis serogroup B (strain MC58)	42%	100%
P65236	Staphylococcus aureus (strain Mu50 / ATCC 700699)	44%	100%
P65237	Staphylococcus aureus (strain N315)	44%	100%
P65238	Staphylococcus aureus (strain MW2)	44%	100%
P65239	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	41%	100%
P65240	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	41%	100%
P65241	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	36%	100%
P65242	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	36%	100%
P65243	Streptococcus pyogenes serotype M1	41%	100%
P65245	Streptococcus pyogenes serotype M18 (strain MGAS8232)	41%	100%
P75044	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	40%	100%
P87171	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P9WKE2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	38%	100%
P9WKE3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	38%	100%
Q08DW2	Bos taurus	31%	100%
Q0ARN5	Maricaulis maris (strain MCS10)	42%	100%
Q0BPP0	Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)	43%	100%
Q0C5A1	Hyphomonas neptunium (strain ATCC 15444)	43%	100%
Q14558	Homo sapiens	31%	100%
Q1LTH2	Baumannia cicadellinicola subsp. Homalodisca coagulata	41%	100%
Q27680	Leishmania donovani	97%	100%
Q28DH0	Xenopus tropicalis	32%	100%
Q2HJ58	Bos taurus	42%	100%
Q42581	Arabidopsis thaliana	39%	92%
Q42583	Arabidopsis thaliana	38%	93%
Q48793	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	42%	100%
Q49V09	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	44%	100%
Q4J9A6	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	25%	100%
Q4L3F7	Staphylococcus haemolyticus (strain JCSC1435)	44%	100%
Q4Q0M2	Leishmania major	48%	100%
Q4Q3Z4	Leishmania major	56%	100%
Q4QI56	Leishmania major	97%	100%
Q4R4R7	Macaca fascicularis	42%	100%
Q4R4U3	Macaca fascicularis	42%	100%
Q54PA9	Dictyostelium discoideum	40%	100%
Q54QU9	Dictyostelium discoideum	36%	100%
Q55848	Synechocystis sp. (strain PCC 6803 / Kazusa)	38%	100%
Q58761	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	29%	100%
Q59988	Synechococcus elongatus (strain PCC 7942 / FACHB-805)	39%	100%
Q5HIH5	Staphylococcus aureus (strain COL)	44%	100%
Q5HRQ5	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	45%	100%
Q5R8F8	Pongo abelii	42%	100%
Q5RBA8	Pongo abelii	33%	100%
Q5RFJ7	Pongo abelii	42%	100%
Q5XC85	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	34%	100%
Q5XEL0	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	41%	100%
Q5XGI0	Xenopus tropicalis	42%	100%
Q5ZI49	Gallus gallus	42%	100%
Q5ZL26	Gallus gallus	33%	100%
Q63468	Rattus norvegicus	31%	100%
Q63XL8	Burkholderia pseudomallei (strain K96243)	42%	100%
Q680A5	Arabidopsis thaliana	25%	100%
Q69XQ6	Oryza sativa subsp. japonica	39%	93%
Q6AJL7	Desulfotalea psychrophila (strain LSv54 / DSM 12343)	42%	100%
Q6GBY8	Staphylococcus aureus (strain MSSA476)	44%	100%
Q6GJH1	Staphylococcus aureus (strain MRSA252)	44%	100%
Q6Z2L5	Oryza sativa subsp. japonica	37%	94%
Q723E1	Listeria monocytogenes serotype 4b (strain F2365)	36%	100%
Q724L4	Listeria monocytogenes serotype 4b (strain F2365)	42%	100%
Q72V73	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	39%	100%
Q75JN8	Dictyostelium discoideum	34%	100%
Q7M8J0	Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)	40%	100%
Q7MMZ1	Vibrio vulnificus (strain YJ016)	44%	100%
Q7MT83	Porphyromonas gingivalis (strain ATCC BAA-308 / W83)	35%	100%
Q7N590	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	43%	100%
Q7NM67	Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)	39%	100%
Q7NQS9	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	42%	100%
Q7U7L5	Parasynechococcus marenigrum (strain WH8102)	39%	100%
Q7UPM4	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	36%	100%
Q7V111	Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)	39%	100%
Q7V6S2	Prochlorococcus marinus (strain MIT 9313)	39%	100%
Q7VBH4	Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)	38%	100%
Q7VFY9	Helicobacter hepaticus (strain ATCC 51449 / 3B1)	43%	100%
Q7VL55	Haemophilus ducreyi (strain 35000HP / ATCC 700724)	41%	100%
Q7VR76	Blochmannia floridanus	39%	100%
Q7VUH1	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	44%	100%
Q7W181	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	44%	100%
Q7WNY4	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	44%	100%
Q7ZXC9	Xenopus laevis	42%	100%
Q81J97	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	42%	100%
Q81VZ0	Bacillus anthracis	42%	100%
Q82HE7	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	39%	100%
Q82TQ4	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	41%	100%
Q82ZA5	Enterococcus faecalis (strain ATCC 700802 / V583)	44%	100%
Q832Z5	Enterococcus faecalis (strain ATCC 700802 / V583)	39%	100%
Q83AQ1	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	41%	100%
Q83TK1	Listeria welshimeri	42%	100%
Q83YI7	Listeria ivanovii	43%	100%
Q87A22	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	40%	100%
Q87RN8	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	44%	100%
Q888C6	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	42%	100%
Q88PX6	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	42%	100%
Q88VA5	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)	36%	100%
Q88Z84	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)	42%	100%
Q899I8	Clostridium tetani (strain Massachusetts / E88)	40%	100%
Q89DJ1	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	45%	100%
Q8CQU7	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	45%	100%
Q8DFF5	Vibrio vulnificus (strain CMCP6)	44%	100%
Q8DU94	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	36%	100%
Q8DWM2	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	42%	100%
Q8DZK4	Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)	36%	100%
Q8E2H0	Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)	41%	100%
Q8E568	Streptococcus agalactiae serotype III (strain NEM316)	36%	100%
Q8E7X8	Streptococcus agalactiae serotype III (strain NEM316)	41%	100%
Q8EAQ9	Shewanella oneidensis (strain MR-1)	43%	100%
Q8EU34	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	43%	100%
Q8EZN0	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	39%	100%
Q8FQV2	Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)	40%	100%
Q8FZF0	Brucella suis biovar 1 (strain 1330)	42%	100%
Q8G5P2	Bifidobacterium longum (strain NCC 2705)	40%	100%
Q8K9X2	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	42%	100%
Q8KCQ2	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	39%	100%
Q8NRU9	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	39%	100%
Q8P137	Streptococcus pyogenes serotype M18 (strain MGAS8232)	33%	100%
Q8PC63	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	42%	100%
Q8PNU0	Xanthomonas axonopodis pv. citri (strain 306)	42%	100%
Q8PUX3	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	27%	100%
Q8R574	Mus musculus	33%	100%
Q8R753	Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)	42%	100%
Q8RHM2	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)	40%	100%
Q8S2E5	Oryza sativa subsp. japonica	23%	91%
Q8TRK8	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	28%	100%
Q8TUT6	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	29%	100%
Q8U458	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	32%	100%
Q8UDA9	Agrobacterium fabrum (strain C58 / ATCC 33970)	42%	100%
Q8XHJ4	Clostridium perfringens (strain 13 / Type A)	41%	100%
Q8Y2E1	Ralstonia solanacearum (strain GMI1000)	43%	100%
Q8Y9L8	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	36%	100%
Q8YIG1	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	42%	100%
Q8YN97	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	38%	100%
Q8ZEY2	Yersinia pestis	42%	100%
Q8ZU24	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	31%	100%
Q92EF1	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	36%	100%
Q92F68	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	42%	100%
Q92N73	Rhizobium meliloti (strain 1021)	42%	100%
Q93Z66	Arabidopsis thaliana	23%	90%
Q973F3	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	26%	100%
Q97CA5	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	29%	100%
Q97E93	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	39%	100%
Q97Z86	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	24%	100%
Q98HW3	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	43%	100%
Q98R83	Mycoplasmopsis pulmonis (strain UAB CTIP)	33%	100%
Q99ZR0	Streptococcus pyogenes serotype M1	34%	100%
Q9AAV6	Caulobacter vibrioides (strain ATCC 19089 / CB15)	43%	100%
Q9CD45	Mycobacterium leprae (strain TN)	39%	100%
Q9CEI4	Lactococcus lactis subsp. lactis (strain IL1403)	35%	100%
Q9CHB8	Lactococcus lactis subsp. lactis (strain IL1403)	44%	100%
Q9CP22	Pasteurella multocida (strain Pm70)	41%	100%
Q9CS42	Mus musculus	42%	100%
Q9D0M1	Mus musculus	31%	100%
Q9D7G0	Mus musculus	42%	100%
Q9EWS0	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	30%	100%
Q9HVC5	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	43%	100%
Q9K3U0	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	39%	100%
Q9KGJ5	Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	44%	100%
Q9KQ22	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	44%	100%
Q9PA76	Xylella fastidiosa (strain 9a5c)	40%	100%
Q9PP15	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	44%	100%
Q9PQV0	Ureaplasma parvum serovar 3 (strain ATCC 700970)	35%	100%
Q9RUD2	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	34%	100%
Q9UY08	Pyrococcus abyssi (strain GE5 / Orsay)	30%	100%
Q9X1W3	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	40%	100%
Q9XG98	Spinacia oleracea	38%	100%
Q9XG99	Spinacia oleracea	40%	94%
Q9XGA0	Spinacia oleracea	24%	91%
Q9XGA1	Spinacia oleracea	24%	100%
Q9ZLA1	Helicobacter pylori (strain J99 / ATCC 700824)	41%	100%
V5BEF5	Trypanosoma cruzi	60%	93%
V5BQA6	Trypanosoma cruzi	49%	95%
V5DQE3	Trypanosoma cruzi	58%	100%