DnaJ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DnaJ domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9AMH3_LEIMU

TriTrypDb:

LmxM.08.0990

Length:

326

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMH3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMH3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	251	255	PF00656	0.670
CLV_NRD_NRD_1	155	157	PF00675	0.437
CLV_NRD_NRD_1	18	20	PF00675	0.477
CLV_NRD_NRD_1	183	185	PF00675	0.312
CLV_NRD_NRD_1	219	221	PF00675	0.242
CLV_NRD_NRD_1	232	234	PF00675	0.587
CLV_NRD_NRD_1	273	275	PF00675	0.503
CLV_NRD_NRD_1	295	297	PF00675	0.485
CLV_NRD_NRD_1	316	318	PF00675	0.525
CLV_NRD_NRD_1	43	45	PF00675	0.350
CLV_PCSK_KEX2_1	119	121	PF00082	0.612
CLV_PCSK_KEX2_1	155	157	PF00082	0.437
CLV_PCSK_KEX2_1	183	185	PF00082	0.312
CLV_PCSK_KEX2_1	272	274	PF00082	0.580
CLV_PCSK_KEX2_1	294	296	PF00082	0.480
CLV_PCSK_KEX2_1	84	86	PF00082	0.458
CLV_PCSK_PC1ET2_1	119	121	PF00082	0.612
CLV_PCSK_PC1ET2_1	272	274	PF00082	0.580
CLV_PCSK_PC1ET2_1	84	86	PF00082	0.458
CLV_PCSK_PC7_1	269	275	PF00082	0.581
CLV_PCSK_SKI1_1	155	159	PF00082	0.430
CLV_PCSK_SKI1_1	203	207	PF00082	0.218
CLV_PCSK_SKI1_1	226	230	PF00082	0.603
CLV_PCSK_SKI1_1	296	300	PF00082	0.554
CLV_PCSK_SKI1_1	45	49	PF00082	0.312
DOC_MAPK_gen_1	220	229	PF00069	0.520
DOC_MAPK_gen_1	315	325	PF00069	0.546
DOC_MAPK_gen_1	41	50	PF00069	0.312
DOC_MAPK_MEF2A_6	41	50	PF00069	0.312
DOC_PP1_RVXF_1	219	226	PF00149	0.445
DOC_SPAK_OSR1_1	224	228	PF12202	0.444
DOC_USP7_MATH_1	103	107	PF00917	0.597
DOC_USP7_MATH_1	132	136	PF00917	0.507
DOC_USP7_MATH_1	260	264	PF00917	0.712
DOC_WW_Pin1_4	19	24	PF00397	0.448
LIG_APCC_ABBA_1	48	53	PF00400	0.312
LIG_BIR_II_1	1	5	PF00653	0.456
LIG_CAP-Gly_1	319	326	PF01302	0.481
LIG_deltaCOP1_diTrp_1	319	326	PF00928	0.481
LIG_eIF4E_1	43	49	PF01652	0.312
LIG_EVH1_2	129	133	PF00568	0.532
LIG_FHA_1	149	155	PF00498	0.370
LIG_FHA_1	31	37	PF00498	0.312
LIG_FHA_2	175	181	PF00498	0.342
LIG_FHA_2	205	211	PF00498	0.332
LIG_FHA_2	263	269	PF00498	0.523
LIG_LIR_Gen_1	163	173	PF02991	0.312
LIG_LIR_Gen_1	204	212	PF02991	0.316
LIG_LIR_Gen_1	22	32	PF02991	0.312
LIG_LIR_Gen_1	319	326	PF02991	0.475
LIG_LIR_Nem_3	163	169	PF02991	0.312
LIG_LIR_Nem_3	204	209	PF02991	0.316
LIG_LIR_Nem_3	22	27	PF02991	0.443
LIG_LIR_Nem_3	319	323	PF02991	0.453
LIG_LIR_Nem_3	77	83	PF02991	0.454
LIG_Pex14_2	225	229	PF04695	0.509
LIG_RPA_C_Fungi	7	19	PF08784	0.395
LIG_SH2_CRK	43	47	PF00017	0.312
LIG_SH2_STAT3	87	90	PF00017	0.544
LIG_SH2_STAT5	165	168	PF00017	0.312
LIG_SUMO_SIM_par_1	167	172	PF11976	0.345
LIG_TRAF2_1	265	268	PF00917	0.547
LIG_TYR_ITSM	161	168	PF00017	0.312
LIG_UBA3_1	79	84	PF00899	0.445
MOD_CK1_1	142	148	PF00069	0.507
MOD_CK1_1	174	180	PF00069	0.414
MOD_CK1_1	75	81	PF00069	0.544
MOD_CK2_1	19	25	PF00069	0.452
MOD_CK2_1	204	210	PF00069	0.312
MOD_CK2_1	262	268	PF00069	0.558
MOD_GlcNHglycan	141	144	PF01048	0.522
MOD_GlcNHglycan	248	251	PF01048	0.619
MOD_GlcNHglycan	99	102	PF01048	0.639
MOD_GSK3_1	139	146	PF00069	0.571
MOD_GSK3_1	204	211	PF00069	0.439
MOD_GSK3_1	97	104	PF00069	0.699
MOD_NEK2_1	139	144	PF00069	0.510
MOD_PIKK_1	134	140	PF00454	0.502
MOD_PIKK_1	72	78	PF00454	0.312
MOD_Plk_1	260	266	PF00069	0.627
MOD_Plk_2-3	204	210	PF00069	0.392
MOD_Plk_4	75	81	PF00069	0.517
MOD_ProDKin_1	19	25	PF00069	0.452
MOD_SUMO_for_1	298	301	PF00179	0.547
MOD_SUMO_rev_2	215	223	PF00179	0.349
TRG_DiLeu_BaEn_1	9	14	PF01217	0.414
TRG_DiLeu_LyEn_5	9	14	PF01217	0.372
TRG_ENDOCYTIC_2	165	168	PF00928	0.312
TRG_ENDOCYTIC_2	185	188	PF00928	0.180
TRG_ENDOCYTIC_2	43	46	PF00928	0.280
TRG_ER_diArg_1	154	156	PF00400	0.454
TRG_ER_diArg_1	183	185	PF00400	0.337
TRG_ER_diArg_1	273	275	PF00400	0.580
TRG_ER_diArg_1	294	296	PF00400	0.480
TRG_NES_CRM1_1	198	210	PF08389	0.312
TRG_Pf-PMV_PEXEL_1	12	17	PF00026	0.367
TRG_Pf-PMV_PEXEL_1	296	300	PF00026	0.554

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIH8	Leptomonas seymouri	76%	98%
A0A3S7WQC4	Leishmania donovani	94%	100%
A4HTN9	Leishmania infantum	95%	100%
Q4QI70	Leishmania major	94%	100%