Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AMG9_LEIMU

TriTrypDb:

LmxM.08.0950

Length:

146

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMG9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMG9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	124	126	PF00675	0.497
CLV_NRD_NRD_1	24	26	PF00675	0.518
CLV_NRD_NRD_1	71	73	PF00675	0.433
CLV_NRD_NRD_1	91	93	PF00675	0.415
CLV_NRD_NRD_1	94	96	PF00675	0.546
CLV_PCSK_FUR_1	92	96	PF00082	0.448
CLV_PCSK_KEX2_1	124	126	PF00082	0.503
CLV_PCSK_KEX2_1	71	73	PF00082	0.438
CLV_PCSK_KEX2_1	91	93	PF00082	0.415
CLV_PCSK_KEX2_1	94	96	PF00082	0.546
CLV_PCSK_SKI1_1	114	118	PF00082	0.471
CLV_PCSK_SKI1_1	125	129	PF00082	0.514
CLV_PCSK_SKI1_1	33	37	PF00082	0.550
DEG_Nend_Nbox_1	1	3	PF02207	0.521
DOC_CYCLIN_RxL_1	111	121	PF00134	0.455
LIG_14-3-3_CanoR_1	25	30	PF00244	0.590
LIG_14-3-3_CanoR_1	40	47	PF00244	0.558
LIG_14-3-3_CanoR_1	63	68	PF00244	0.556
LIG_14-3-3_CanoR_1	71	75	PF00244	0.499
LIG_14-3-3_CanoR_1	9	15	PF00244	0.492
LIG_BRCT_BRCA1_1	2	6	PF00533	0.514
LIG_CaM_IQ_9	116	131	PF13499	0.450
LIG_FHA_1	121	127	PF00498	0.532
LIG_FHA_1	3	9	PF00498	0.622
LIG_FHA_2	100	106	PF00498	0.576
LIG_FHA_2	43	49	PF00498	0.339
LIG_LIR_Gen_1	45	52	PF02991	0.333
LIG_LIR_Nem_3	45	50	PF02991	0.334
LIG_SH2_NCK_1	83	87	PF00017	0.597
LIG_SH2_STAP1	83	87	PF00017	0.584
LIG_WRC_WIRS_1	1	6	PF05994	0.518
MOD_CK2_1	42	48	PF00069	0.494
MOD_Cter_Amidation	69	72	PF01082	0.426
MOD_GSK3_1	21	28	PF00069	0.532
MOD_GSK3_1	36	43	PF00069	0.555
MOD_GSK3_1	9	16	PF00069	0.564
MOD_LATS_1	23	29	PF00433	0.566
MOD_NEK2_1	2	7	PF00069	0.555
MOD_NEK2_1	29	34	PF00069	0.522
MOD_NEK2_1	36	41	PF00069	0.458
MOD_NEK2_1	8	13	PF00069	0.517
MOD_PIKK_1	129	135	PF00454	0.609
MOD_PIKK_1	40	46	PF00454	0.531
MOD_PKA_1	25	31	PF00069	0.571
MOD_PKA_2	100	106	PF00069	0.557
MOD_PKA_2	29	35	PF00069	0.507
MOD_PKA_2	70	76	PF00069	0.500
MOD_PKA_2	8	14	PF00069	0.559
MOD_PKB_1	40	48	PF00069	0.574
TRG_ER_diArg_1	124	126	PF00400	0.555
TRG_NLS_MonoExtN_4	125	132	PF00514	0.493
TRG_Pf-PMV_PEXEL_1	114	118	PF00026	0.502

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3W2	Leptomonas seymouri	66%	100%
A0A1X0NPN9	Trypanosomatidae	38%	95%
A0A3S5H677	Leishmania donovani	88%	100%
A4H5E0	Leishmania braziliensis	78%	100%
A4HTN5	Leishmania infantum	88%	100%
Q4QI74	Leishmania major	86%	100%