Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AMG0_LEIMU

TriTrypDb:

LmxM.08.0860

Length:

290

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMG0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMG0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	150	154	PF00656	0.670
CLV_C14_Caspase3-7	157	161	PF00656	0.599
CLV_C14_Caspase3-7	177	181	PF00656	0.665
CLV_NRD_NRD_1	214	216	PF00675	0.780
CLV_NRD_NRD_1	29	31	PF00675	0.630
CLV_NRD_NRD_1	6	8	PF00675	0.663
CLV_PCSK_KEX2_1	214	216	PF00082	0.756
CLV_PCSK_KEX2_1	29	31	PF00082	0.630
CLV_PCSK_KEX2_1	5	7	PF00082	0.660
CLV_PCSK_SKI1_1	29	33	PF00082	0.485
DOC_MAPK_gen_1	101	109	PF00069	0.641
DOC_PP4_FxxP_1	205	208	PF00568	0.567
DOC_PP4_MxPP_1	199	202	PF00568	0.691
DOC_USP7_MATH_1	20	24	PF00917	0.771
DOC_USP7_MATH_1	210	214	PF00917	0.682
DOC_USP7_MATH_1	225	229	PF00917	0.599
DOC_USP7_MATH_1	47	51	PF00917	0.521
DOC_USP7_UBL2_3	133	137	PF12436	0.645
DOC_WW_Pin1_4	22	27	PF00397	0.621
DOC_WW_Pin1_4	221	226	PF00397	0.625
DOC_WW_Pin1_4	233	238	PF00397	0.601
DOC_WW_Pin1_4	257	262	PF00397	0.564
LIG_AP2alpha_1	205	209	PF02296	0.712
LIG_AP2alpha_2	187	189	PF02296	0.679
LIG_AP2alpha_2	207	209	PF02296	0.485
LIG_AP2alpha_2	284	286	PF02296	0.482
LIG_BRCT_BRCA1_1	80	84	PF00533	0.499
LIG_deltaCOP1_diTrp_1	183	189	PF00928	0.640
LIG_EVH1_2	201	205	PF00568	0.698
LIG_FHA_1	37	43	PF00498	0.524
LIG_FHA_2	62	68	PF00498	0.436
LIG_LIR_Apic_2	183	188	PF02991	0.723
LIG_LIR_Gen_1	284	290	PF02991	0.482
LIG_LIR_Nem_3	284	289	PF02991	0.497
LIG_LIR_Nem_3	50	56	PF02991	0.473
LIG_LIR_Nem_3	81	87	PF02991	0.478
LIG_Pex14_2	205	209	PF04695	0.712
LIG_Pex14_2	248	252	PF04695	0.503
LIG_SH2_GRB2like	56	59	PF00017	0.449
LIG_SH2_NCK_1	158	162	PF00017	0.671
LIG_SH2_STAP1	53	57	PF00017	0.476
LIG_SH2_STAT5	238	241	PF00017	0.568
LIG_SH2_STAT5	86	89	PF00017	0.548
LIG_SH3_2	258	263	PF14604	0.561
LIG_SH3_3	146	152	PF00018	0.636
LIG_SH3_3	176	182	PF00018	0.524
LIG_SH3_3	255	261	PF00018	0.560
LIG_SUMO_SIM_par_1	105	111	PF11976	0.707
LIG_TRAF2_1	64	67	PF00917	0.461
MOD_CDC14_SPxK_1	260	263	PF00782	0.543
MOD_CDK_SPxK_1	257	263	PF00069	0.563
MOD_CDK_SPxxK_3	22	29	PF00069	0.608
MOD_CDK_SPxxK_3	233	240	PF00069	0.654
MOD_CK1_1	228	234	PF00069	0.717
MOD_CK1_1	236	242	PF00069	0.600
MOD_CK2_1	22	28	PF00069	0.581
MOD_CK2_1	61	67	PF00069	0.426
MOD_Cter_Amidation	169	172	PF01082	0.734
MOD_GlcNHglycan	123	126	PF01048	0.676
MOD_GlcNHglycan	168	171	PF01048	0.772
MOD_GlcNHglycan	21	25	PF01048	0.572
MOD_GlcNHglycan	225	228	PF01048	0.653
MOD_GlcNHglycan	80	83	PF01048	0.581
MOD_GlcNHglycan	97	100	PF01048	0.503
MOD_GSK3_1	119	126	PF00069	0.590
MOD_GSK3_1	156	163	PF00069	0.739
MOD_GSK3_1	221	228	PF00069	0.685
MOD_GSK3_1	34	41	PF00069	0.511
MOD_GSK3_1	78	85	PF00069	0.487
MOD_N-GLC_1	95	100	PF02516	0.565
MOD_NEK2_1	252	257	PF00069	0.646
MOD_NEK2_1	78	83	PF00069	0.487
MOD_PKA_1	6	12	PF00069	0.655
MOD_PKA_2	140	146	PF00069	0.683
MOD_PKA_2	174	180	PF00069	0.604
MOD_PKA_2	6	12	PF00069	0.663
MOD_Plk_1	95	101	PF00069	0.564
MOD_Plk_2-3	61	67	PF00069	0.426
MOD_Plk_4	190	196	PF00069	0.638
MOD_Plk_4	38	44	PF00069	0.468
MOD_ProDKin_1	22	28	PF00069	0.612
MOD_ProDKin_1	221	227	PF00069	0.624
MOD_ProDKin_1	233	239	PF00069	0.599
MOD_ProDKin_1	257	263	PF00069	0.568
TRG_ER_diArg_1	103	106	PF00400	0.672
TRG_ER_diArg_1	29	31	PF00400	0.630
TRG_ER_diArg_1	5	7	PF00400	0.660

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEG2	Leptomonas seymouri	39%	100%
A0A3S5H670	Leishmania donovani	84%	100%
A4H6C7	Leishmania braziliensis	59%	100%
A4HTM6	Leishmania infantum	84%	100%
Q4QI83	Leishmania major	81%	100%