POP1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AMC9_LEIMU

TriTrypDb:

LmxM.08.0500

Length:

328

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMC9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMC9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	123	125	PF00675	0.752
CLV_NRD_NRD_1	17	19	PF00675	0.712
CLV_NRD_NRD_1	196	198	PF00675	0.688
CLV_NRD_NRD_1	281	283	PF00675	0.732
CLV_NRD_NRD_1	301	303	PF00675	0.413
CLV_NRD_NRD_1	316	318	PF00675	0.479
CLV_NRD_NRD_1	4	6	PF00675	0.754
CLV_PCSK_KEX2_1	123	125	PF00082	0.752
CLV_PCSK_KEX2_1	17	19	PF00082	0.675
CLV_PCSK_KEX2_1	195	197	PF00082	0.863
CLV_PCSK_KEX2_1	280	282	PF00082	0.745
CLV_PCSK_KEX2_1	301	303	PF00082	0.630
CLV_PCSK_KEX2_1	316	318	PF00082	0.479
CLV_PCSK_PC1ET2_1	195	197	PF00082	0.749
CLV_PCSK_PC7_1	277	283	PF00082	0.744
CLV_PCSK_SKI1_1	18	22	PF00082	0.713
CLV_PCSK_SKI1_1	245	249	PF00082	0.706
DEG_APCC_DBOX_1	52	60	PF00400	0.737
DOC_CYCLIN_yCln2_LP_2	74	80	PF00134	0.612
DOC_MAPK_gen_1	316	324	PF00069	0.535
DOC_MAPK_gen_1	50	59	PF00069	0.493
DOC_USP7_MATH_1	122	126	PF00917	0.746
DOC_USP7_MATH_1	310	314	PF00917	0.623
DOC_USP7_MATH_1	48	52	PF00917	0.601
DOC_USP7_MATH_1	88	92	PF00917	0.579
DOC_USP7_UBL2_3	172	176	PF12436	0.531
DOC_WW_Pin1_4	127	132	PF00397	0.635
DOC_WW_Pin1_4	175	180	PF00397	0.807
DOC_WW_Pin1_4	225	230	PF00397	0.772
DOC_WW_Pin1_4	286	291	PF00397	0.687
DOC_WW_Pin1_4	29	34	PF00397	0.798
DOC_WW_Pin1_4	73	78	PF00397	0.691
LIG_14-3-3_CanoR_1	112	121	PF00244	0.693
LIG_14-3-3_CanoR_1	123	131	PF00244	0.670
LIG_14-3-3_CanoR_1	301	308	PF00244	0.679
LIG_14-3-3_CanoR_1	316	325	PF00244	0.475
LIG_14-3-3_CanoR_1	44	52	PF00244	0.541
LIG_BIR_III_2	128	132	PF00653	0.632
LIG_BIR_III_4	81	85	PF00653	0.552
LIG_BRCT_BRCA1_1	233	237	PF00533	0.476
LIG_deltaCOP1_diTrp_1	150	158	PF00928	0.561
LIG_deltaCOP1_diTrp_1	243	248	PF00928	0.696
LIG_eIF4E_1	65	71	PF01652	0.720
LIG_FHA_1	116	122	PF00498	0.582
LIG_FHA_1	144	150	PF00498	0.820
LIG_FHA_1	319	325	PF00498	0.622
LIG_FHA_2	291	297	PF00498	0.708
LIG_LIR_Gen_1	234	243	PF02991	0.464
LIG_LIR_Nem_3	148	154	PF02991	0.755
LIG_LIR_Nem_3	156	161	PF02991	0.650
LIG_LIR_Nem_3	234	240	PF02991	0.634
LIG_LIR_Nem_3	241	247	PF02991	0.689
LIG_PDZ_Class_3	323	328	PF00595	0.685
LIG_Pex14_1	244	248	PF04695	0.636
LIG_REV1ctd_RIR_1	245	255	PF16727	0.656
LIG_SH2_NCK_1	303	307	PF00017	0.609
LIG_SH2_NCK_1	65	69	PF00017	0.714
LIG_SH2_STAP1	303	307	PF00017	0.609
LIG_SH2_STAT5	303	306	PF00017	0.679
LIG_SH2_STAT5	65	68	PF00017	0.715
LIG_SH3_3	27	33	PF00018	0.573
LIG_TRAF2_1	60	63	PF00917	0.718
MOD_CK1_1	143	149	PF00069	0.740
MOD_CK1_1	228	234	PF00069	0.671
MOD_CK2_1	150	156	PF00069	0.735
MOD_CK2_1	290	296	PF00069	0.723
MOD_CK2_1	48	54	PF00069	0.537
MOD_Cter_Amidation	193	196	PF01082	0.816
MOD_DYRK1A_RPxSP_1	29	33	PF00069	0.736
MOD_GlcNHglycan	102	105	PF01048	0.684
MOD_GlcNHglycan	124	127	PF01048	0.771
MOD_GlcNHglycan	232	236	PF01048	0.476
MOD_GlcNHglycan	260	263	PF01048	0.691
MOD_GlcNHglycan	264	267	PF01048	0.624
MOD_GlcNHglycan	312	315	PF01048	0.638
MOD_GlcNHglycan	46	49	PF01048	0.677
MOD_GSK3_1	127	134	PF00069	0.624
MOD_GSK3_1	136	143	PF00069	0.834
MOD_GSK3_1	145	152	PF00069	0.666
MOD_GSK3_1	178	185	PF00069	0.794
MOD_GSK3_1	258	265	PF00069	0.665
MOD_GSK3_1	286	293	PF00069	0.741
MOD_GSK3_1	44	51	PF00069	0.658
MOD_GSK3_1	88	95	PF00069	0.577
MOD_N-GLC_1	284	289	PF02516	0.626
MOD_N-GLC_1	44	49	PF02516	0.588
MOD_NEK2_1	236	241	PF00069	0.561
MOD_NEK2_1	258	263	PF00069	0.670
MOD_NEK2_1	92	97	PF00069	0.748
MOD_PIKK_1	143	149	PF00454	0.594
MOD_PIKK_1	58	64	PF00454	0.714
MOD_PIKK_1	86	92	PF00454	0.557
MOD_PKA_1	301	307	PF00069	0.616
MOD_PKA_2	122	128	PF00069	0.747
MOD_PKA_2	301	307	PF00069	0.616
MOD_Plk_1	149	155	PF00069	0.607
MOD_Plk_1	231	237	PF00069	0.577
MOD_Plk_2-3	150	156	PF00069	0.635
MOD_Plk_4	66	72	PF00069	0.641
MOD_Plk_4	88	94	PF00069	0.558
MOD_ProDKin_1	127	133	PF00069	0.637
MOD_ProDKin_1	175	181	PF00069	0.809
MOD_ProDKin_1	225	231	PF00069	0.766
MOD_ProDKin_1	286	292	PF00069	0.680
MOD_ProDKin_1	29	35	PF00069	0.800
MOD_ProDKin_1	73	79	PF00069	0.694
TRG_DiLeu_BaLyEn_6	69	74	PF01217	0.742
TRG_ENDOCYTIC_2	154	157	PF00928	0.717
TRG_ER_diArg_1	17	19	PF00400	0.684
TRG_ER_diArg_1	280	282	PF00400	0.812
TRG_ER_diArg_1	300	302	PF00400	0.402
TRG_NLS_MonoExtC_3	194	200	PF00514	0.569
TRG_NLS_MonoExtN_4	2	9	PF00514	0.651

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H654	Leishmania donovani	71%	90%
A4H5B7	Leishmania braziliensis	50%	100%
A4HTJ8	Leishmania infantum	72%	91%
Q4QIB9	Leishmania major	73%	99%