LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Putative small ubiquitin protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative small ubiquitin protein
Gene product:
small ubiquitin protein, putative
Species:
Leishmania mexicana
UniProt:
E9AMC6_LEIMU
TriTrypDb:
LmxM.08.0470
Length:
117

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 25
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 1
GO:0005730 nucleolus 5 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9AMC6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMC6

Function

Biological processes
Term Name Level Count
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 1
GO:0016925 protein sumoylation 7 1
GO:0018193 peptidyl-amino acid modification 5 1
GO:0018205 peptidyl-lysine modification 6 1
GO:0019538 protein metabolic process 3 1
GO:0032446 protein modification by small protein conjugation 6 1
GO:0036211 protein modification process 4 1
GO:0043170 macromolecule metabolic process 3 1
GO:0043412 macromolecule modification 4 1
GO:0044238 primary metabolic process 2 1
GO:0070647 protein modification by small protein conjugation or removal 5 1
GO:0071704 organic substance metabolic process 2 1
GO:1901564 organonitrogen compound metabolic process 3 1
Molecular functions
Term Name Level Count
GO:0005488 binding 1 1
GO:0005515 protein binding 2 1
GO:0019899 enzyme binding 3 1
GO:0031386 protein tag 1 1
GO:0044389 ubiquitin-like protein ligase binding 4 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 100 104 PF00656 0.356
CLV_PCSK_KEX2_1 53 55 PF00082 0.468
CLV_PCSK_PC1ET2_1 53 55 PF00082 0.468
CLV_PCSK_SKI1_1 77 81 PF00082 0.356
DEG_Nend_UBRbox_2 1 3 PF02207 0.674
DOC_CKS1_1 88 93 PF01111 0.423
DOC_USP7_MATH_1 29 33 PF00917 0.662
DOC_WW_Pin1_4 87 92 PF00397 0.380
LIG_BRCT_BRCA1_1 74 78 PF00533 0.356
LIG_CtBP_PxDLS_1 91 95 PF00389 0.429
LIG_FHA_2 88 94 PF00498 0.359
LIG_LIR_Nem_3 47 52 PF02991 0.344
LIG_Rb_pABgroove_1 74 82 PF01858 0.394
LIG_REV1ctd_RIR_1 47 58 PF16727 0.356
LIG_SH2_STAT5 65 68 PF00017 0.340
LIG_UBA3_1 48 53 PF00899 0.356
MOD_CK1_1 72 78 PF00069 0.351
MOD_GlcNHglycan 31 34 PF01048 0.697
MOD_PIKK_1 53 59 PF00454 0.376
MOD_PKA_1 53 59 PF00069 0.468
MOD_PKA_2 53 59 PF00069 0.468
MOD_PKA_2 72 78 PF00069 0.356
MOD_Plk_4 109 115 PF00069 0.432
MOD_ProDKin_1 87 93 PF00069 0.380
MOD_SUMO_for_1 23 26 PF00179 0.654
MOD_SUMO_rev_2 81 91 PF00179 0.356
TRG_Pf-PMV_PEXEL_1 77 81 PF00026 0.356

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P930 Leptomonas seymouri 82% 94%
A0A1X0NP22 Trypanosomatidae 80% 100%
A0A3R7N9J1 Trypanosoma rangeli 84% 100%
A0A3S5H652 Leishmania donovani 97% 100%
A4H5B4 Leishmania braziliensis 91% 100%
A4HTJ5 Leishmania infantum 97% 100%
A7WLH8 Sus scrofa 49% 100%
B3H5R8 Arabidopsis thaliana 43% 100%
C9ZPI0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 64% 100%
G2XKQ0 Homo sapiens 43% 100%
O13351 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 50% 100%
P55853 Caenorhabditis elegans 46% 100%
P55857 Oryza sativa subsp. japonica 48% 100%
P63165 Homo sapiens 49% 100%
P63166 Mus musculus 49% 100%
Q12306 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 47% 100%
Q17QV3 Bos taurus 56% 100%
Q28H04 Xenopus tropicalis 50% 100%
Q2EF74 Ictidomys tridecemlineatus 49% 100%
Q3E8A8 Arabidopsis thaliana 34% 100%
Q4QIC2 Leishmania major 96% 100%
Q5E9D1 Bos taurus 49% 100%
Q5I0H3 Rattus norvegicus 49% 100%
Q5R6J4 Pongo abelii 49% 100%
Q5XIF4 Rattus norvegicus 54% 100%
Q6DHL4 Danio rerio 47% 100%
Q6DI05 Danio rerio 55% 100%
Q6GPW2 Xenopus laevis 51% 100%
Q6NV25 Danio rerio 55% 100%
Q7SZR5 Danio rerio 45% 100%
Q8QGH2 Gallus gallus 49% 100%
Q9FKC5 Arabidopsis thaliana 40% 100%
Q9FKC6 Arabidopsis thaliana 29% 100%
Q9FLP5 Arabidopsis thaliana 39% 100%
Q9MZD5 Cervus nippon 49% 100%
Q9PT08 Oncorhynchus mykiss 43% 100%
Q9Z172 Mus musculus 55% 100%
V5BLK4 Trypanosoma cruzi 87% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS