Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AMA6_LEIMU

TriTrypDb:

LmxM.08.0270

Length:

833

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AMA6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AMA6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	172	176	PF00656	0.512
CLV_C14_Caspase3-7	415	419	PF00656	0.632
CLV_C14_Caspase3-7	631	635	PF00656	0.683
CLV_MEL_PAP_1	153	159	PF00089	0.535
CLV_NRD_NRD_1	198	200	PF00675	0.665
CLV_NRD_NRD_1	346	348	PF00675	0.601
CLV_NRD_NRD_1	421	423	PF00675	0.761
CLV_NRD_NRD_1	547	549	PF00675	0.700
CLV_NRD_NRD_1	62	64	PF00675	0.418
CLV_NRD_NRD_1	701	703	PF00675	0.781
CLV_NRD_NRD_1	773	775	PF00675	0.558
CLV_NRD_NRD_1	810	812	PF00675	0.566
CLV_PCSK_FUR_1	542	546	PF00082	0.655
CLV_PCSK_KEX2_1	113	115	PF00082	0.620
CLV_PCSK_KEX2_1	198	200	PF00082	0.665
CLV_PCSK_KEX2_1	346	348	PF00082	0.524
CLV_PCSK_KEX2_1	544	546	PF00082	0.656
CLV_PCSK_KEX2_1	547	549	PF00082	0.746
CLV_PCSK_KEX2_1	62	64	PF00082	0.466
CLV_PCSK_KEX2_1	66	68	PF00082	0.515
CLV_PCSK_KEX2_1	773	775	PF00082	0.558
CLV_PCSK_KEX2_1	801	803	PF00082	0.593
CLV_PCSK_KEX2_1	810	812	PF00082	0.524
CLV_PCSK_PC1ET2_1	113	115	PF00082	0.825
CLV_PCSK_PC1ET2_1	66	68	PF00082	0.518
CLV_PCSK_PC1ET2_1	801	803	PF00082	0.697
CLV_PCSK_PC7_1	542	548	PF00082	0.566
CLV_PCSK_PC7_1	62	68	PF00082	0.398
CLV_PCSK_SKI1_1	165	169	PF00082	0.563
CLV_PCSK_SKI1_1	25	29	PF00082	0.573
CLV_PCSK_SKI1_1	385	389	PF00082	0.730
CLV_PCSK_SKI1_1	63	67	PF00082	0.542
CLV_PCSK_SKI1_1	746	750	PF00082	0.661
DEG_ODPH_VHL_1	327	339	PF01847	0.641
DEG_SPOP_SBC_1	115	119	PF00917	0.675
DEG_SPOP_SBC_1	235	239	PF00917	0.528
DOC_CKS1_1	435	440	PF01111	0.541
DOC_CKS1_1	592	597	PF01111	0.543
DOC_CKS1_1	728	733	PF01111	0.650
DOC_CYCLIN_yCln2_LP_2	435	441	PF00134	0.541
DOC_MAPK_gen_1	815	824	PF00069	0.620
DOC_MAPK_MEF2A_6	746	755	PF00069	0.643
DOC_PP2B_LxvP_1	454	457	PF13499	0.610
DOC_USP7_MATH_1	115	119	PF00917	0.684
DOC_USP7_MATH_1	210	214	PF00917	0.600
DOC_USP7_MATH_1	269	273	PF00917	0.656
DOC_USP7_MATH_1	27	31	PF00917	0.566
DOC_USP7_MATH_1	293	297	PF00917	0.625
DOC_USP7_MATH_1	299	303	PF00917	0.691
DOC_USP7_MATH_1	329	333	PF00917	0.672
DOC_USP7_MATH_1	387	391	PF00917	0.680
DOC_USP7_MATH_1	458	462	PF00917	0.636
DOC_USP7_MATH_1	503	507	PF00917	0.730
DOC_USP7_MATH_1	511	515	PF00917	0.620
DOC_USP7_MATH_1	607	611	PF00917	0.592
DOC_USP7_MATH_1	661	665	PF00917	0.577
DOC_USP7_MATH_1	738	742	PF00917	0.757
DOC_USP7_MATH_1	788	792	PF00917	0.555
DOC_USP7_MATH_1	81	85	PF00917	0.667
DOC_USP7_UBL2_3	79	83	PF12436	0.728
DOC_WW_Pin1_4	249	254	PF00397	0.702
DOC_WW_Pin1_4	434	439	PF00397	0.667
DOC_WW_Pin1_4	469	474	PF00397	0.620
DOC_WW_Pin1_4	583	588	PF00397	0.737
DOC_WW_Pin1_4	591	596	PF00397	0.719
DOC_WW_Pin1_4	636	641	PF00397	0.681
DOC_WW_Pin1_4	659	664	PF00397	0.789
DOC_WW_Pin1_4	71	76	PF00397	0.604
DOC_WW_Pin1_4	727	732	PF00397	0.593
DOC_WW_Pin1_4	739	744	PF00397	0.626
DOC_WW_Pin1_4	784	789	PF00397	0.679
DOC_WW_Pin1_4	82	87	PF00397	0.652
LIG_14-3-3_CanoR_1	156	166	PF00244	0.569
LIG_14-3-3_CanoR_1	266	274	PF00244	0.509
LIG_14-3-3_CanoR_1	31	36	PF00244	0.550
LIG_14-3-3_CanoR_1	313	322	PF00244	0.652
LIG_14-3-3_CanoR_1	377	383	PF00244	0.568
LIG_14-3-3_CanoR_1	385	394	PF00244	0.693
LIG_14-3-3_CanoR_1	403	408	PF00244	0.443
LIG_14-3-3_CanoR_1	502	508	PF00244	0.599
LIG_14-3-3_CanoR_1	545	553	PF00244	0.676
LIG_14-3-3_CanoR_1	597	602	PF00244	0.589
LIG_14-3-3_CanoR_1	666	676	PF00244	0.617
LIG_14-3-3_CanoR_1	67	75	PF00244	0.669
LIG_14-3-3_CanoR_1	702	711	PF00244	0.534
LIG_14-3-3_CanoR_1	720	728	PF00244	0.620
LIG_14-3-3_CanoR_1	773	779	PF00244	0.577
LIG_14-3-3_CanoR_1	90	99	PF00244	0.689
LIG_14-3-3_CterR_2	831	833	PF00244	0.592
LIG_Actin_WH2_2	150	167	PF00022	0.622
LIG_BIR_II_1	1	5	PF00653	0.681
LIG_CtBP_PxDLS_1	827	831	PF00389	0.560
LIG_deltaCOP1_diTrp_1	765	768	PF00928	0.532
LIG_DLG_GKlike_1	403	411	PF00625	0.458
LIG_FHA_1	223	229	PF00498	0.512
LIG_FHA_1	377	383	PF00498	0.615
LIG_FHA_1	403	409	PF00498	0.665
LIG_FHA_1	445	451	PF00498	0.661
LIG_FHA_1	669	675	PF00498	0.664
LIG_FHA_1	730	736	PF00498	0.574
LIG_FHA_2	117	123	PF00498	0.722
LIG_FHA_2	170	176	PF00498	0.595
LIG_FHA_2	473	479	PF00498	0.566
LIG_FHA_2	569	575	PF00498	0.717
LIG_HCF-1_HBM_1	330	333	PF13415	0.471
LIG_IRF3_LxIS_1	827	833	PF10401	0.553
LIG_LIR_Gen_1	146	157	PF02991	0.691
LIG_LIR_Gen_1	332	342	PF02991	0.602
LIG_LIR_Gen_1	760	768	PF02991	0.529
LIG_LIR_Nem_3	146	152	PF02991	0.678
LIG_LIR_Nem_3	330	336	PF02991	0.591
LIG_LIR_Nem_3	559	563	PF02991	0.582
LIG_LIR_Nem_3	760	764	PF02991	0.595
LIG_Pex14_1	556	560	PF04695	0.579
LIG_PTB_Apo_2	332	339	PF02174	0.618
LIG_PTB_Phospho_1	332	338	PF10480	0.617
LIG_SH2_CRK	334	338	PF00017	0.599
LIG_SH2_CRK	563	567	PF00017	0.593
LIG_SH2_GRB2like	333	336	PF00017	0.619
LIG_SH2_GRB2like	563	566	PF00017	0.647
LIG_SH2_NCK_1	334	338	PF00017	0.622
LIG_SH2_NCK_1	563	567	PF00017	0.593
LIG_SH2_NCK_1	761	765	PF00017	0.640
LIG_SH2_SRC	563	566	PF00017	0.647
LIG_SH2_STAP1	126	130	PF00017	0.458
LIG_SH2_STAT3	130	133	PF00017	0.444
LIG_SH2_STAT3	57	60	PF00017	0.452
LIG_SH2_STAT5	130	133	PF00017	0.728
LIG_SH2_STAT5	338	341	PF00017	0.624
LIG_SH2_STAT5	407	410	PF00017	0.563
LIG_SH3_1	422	428	PF00018	0.685
LIG_SH3_2	592	597	PF14604	0.543
LIG_SH3_3	188	194	PF00018	0.674
LIG_SH3_3	418	424	PF00018	0.682
LIG_SH3_3	581	587	PF00018	0.637
LIG_SH3_3	589	595	PF00018	0.748
LIG_SH3_3	657	663	PF00018	0.658
LIG_SH3_3	69	75	PF00018	0.520
LIG_SH3_3	708	714	PF00018	0.655
LIG_SUMO_SIM_par_1	38	43	PF11976	0.460
LIG_SUMO_SIM_par_1	669	678	PF11976	0.663
LIG_TRAF2_1	278	281	PF00917	0.604
LIG_TRAF2_2	290	295	PF00917	0.633
LIG_TRAF2_2	4	9	PF00917	0.526
MOD_CDK_SPxK_1	591	597	PF00069	0.543
MOD_CDK_SPxxK_3	659	666	PF00069	0.585
MOD_CDK_SPxxK_3	739	746	PF00069	0.508
MOD_CK1_1	15	21	PF00069	0.509
MOD_CK1_1	160	166	PF00069	0.541
MOD_CK1_1	2	8	PF00069	0.676
MOD_CK1_1	236	242	PF00069	0.730
MOD_CK1_1	272	278	PF00069	0.681
MOD_CK1_1	472	478	PF00069	0.620
MOD_CK1_1	487	493	PF00069	0.643
MOD_CK1_1	506	512	PF00069	0.527
MOD_CK1_1	585	591	PF00069	0.730
MOD_CK1_1	685	691	PF00069	0.604
MOD_CK1_1	701	707	PF00069	0.698
MOD_CK1_1	741	747	PF00069	0.773
MOD_CK1_1	787	793	PF00069	0.498
MOD_CK2_1	464	470	PF00069	0.667
MOD_GlcNHglycan	1	4	PF01048	0.735
MOD_GlcNHglycan	100	103	PF01048	0.727
MOD_GlcNHglycan	122	126	PF01048	0.558
MOD_GlcNHglycan	239	242	PF01048	0.756
MOD_GlcNHglycan	263	266	PF01048	0.632
MOD_GlcNHglycan	324	327	PF01048	0.500
MOD_GlcNHglycan	348	351	PF01048	0.665
MOD_GlcNHglycan	353	356	PF01048	0.625
MOD_GlcNHglycan	44	47	PF01048	0.468
MOD_GlcNHglycan	460	463	PF01048	0.582
MOD_GlcNHglycan	497	500	PF01048	0.762
MOD_GlcNHglycan	505	508	PF01048	0.659
MOD_GlcNHglycan	620	623	PF01048	0.727
MOD_GlcNHglycan	693	696	PF01048	0.545
MOD_GlcNHglycan	732	735	PF01048	0.763
MOD_GlcNHglycan	790	793	PF01048	0.644
MOD_GSK3_1	233	240	PF00069	0.690
MOD_GSK3_1	249	256	PF00069	0.560
MOD_GSK3_1	27	34	PF00069	0.589
MOD_GSK3_1	295	302	PF00069	0.535
MOD_GSK3_1	385	392	PF00069	0.654
MOD_GSK3_1	472	479	PF00069	0.607
MOD_GSK3_1	484	491	PF00069	0.597
MOD_GSK3_1	578	585	PF00069	0.727
MOD_GSK3_1	587	594	PF00069	0.726
MOD_GSK3_1	597	604	PF00069	0.502
MOD_GSK3_1	614	621	PF00069	0.759
MOD_GSK3_1	648	655	PF00069	0.648
MOD_GSK3_1	66	73	PF00069	0.566
MOD_GSK3_1	666	673	PF00069	0.689
MOD_GSK3_1	682	689	PF00069	0.565
MOD_GSK3_1	719	726	PF00069	0.678
MOD_GSK3_1	738	745	PF00069	0.574
MOD_GSK3_1	784	791	PF00069	0.588
MOD_GSK3_1	82	89	PF00069	0.553
MOD_GSK3_1	98	105	PF00069	0.633
MOD_LATS_1	344	350	PF00433	0.518
MOD_N-GLC_1	463	468	PF02516	0.718
MOD_N-GLC_1	704	709	PF02516	0.672
MOD_NEK2_1	35	40	PF00069	0.489
MOD_NEK2_1	402	407	PF00069	0.589
MOD_NEK2_1	486	491	PF00069	0.573
MOD_NEK2_1	654	659	PF00069	0.517
MOD_NEK2_1	675	680	PF00069	0.625
MOD_NEK2_1	682	687	PF00069	0.632
MOD_NEK2_2	299	304	PF00069	0.499
MOD_OGLYCOS	71	76	PF02709	0.488
MOD_PIKK_1	155	161	PF00454	0.520
MOD_PIKK_1	2	8	PF00454	0.598
MOD_PIKK_1	210	216	PF00454	0.626
MOD_PIKK_1	269	275	PF00454	0.648
MOD_PIKK_1	313	319	PF00454	0.669
MOD_PIKK_1	40	46	PF00454	0.556
MOD_PIKK_1	597	603	PF00454	0.529
MOD_PIKK_1	66	72	PF00454	0.590
MOD_PK_1	524	530	PF00069	0.606
MOD_PK_1	547	553	PF00069	0.709
MOD_PKA_1	346	352	PF00069	0.529
MOD_PKA_1	546	552	PF00069	0.691
MOD_PKA_1	66	72	PF00069	0.590
MOD_PKA_1	773	779	PF00069	0.484
MOD_PKA_2	15	21	PF00069	0.651
MOD_PKA_2	155	161	PF00069	0.545
MOD_PKA_2	312	318	PF00069	0.652
MOD_PKA_2	346	352	PF00069	0.584
MOD_PKA_2	376	382	PF00069	0.728
MOD_PKA_2	402	408	PF00069	0.494
MOD_PKA_2	493	499	PF00069	0.693
MOD_PKA_2	546	552	PF00069	0.726
MOD_PKA_2	66	72	PF00069	0.590
MOD_PKA_2	701	707	PF00069	0.525
MOD_PKA_2	719	725	PF00069	0.584
MOD_PKA_2	773	779	PF00069	0.484
MOD_PKA_2	91	97	PF00069	0.704
MOD_PKB_1	544	552	PF00069	0.671
MOD_PKB_1	90	98	PF00069	0.544
MOD_Plk_1	299	305	PF00069	0.579
MOD_Plk_1	329	335	PF00069	0.632
MOD_Plk_1	445	451	PF00069	0.510
MOD_Plk_4	329	335	PF00069	0.474
MOD_Plk_4	35	41	PF00069	0.490
MOD_Plk_4	403	409	PF00069	0.600
MOD_Plk_4	445	451	PF00069	0.635
MOD_Plk_4	547	553	PF00069	0.687
MOD_Plk_4	601	607	PF00069	0.539
MOD_Plk_4	670	676	PF00069	0.659
MOD_Plk_4	723	729	PF00069	0.529
MOD_Plk_4	790	796	PF00069	0.619
MOD_ProDKin_1	249	255	PF00069	0.701
MOD_ProDKin_1	434	440	PF00069	0.663
MOD_ProDKin_1	469	475	PF00069	0.619
MOD_ProDKin_1	583	589	PF00069	0.737
MOD_ProDKin_1	591	597	PF00069	0.722
MOD_ProDKin_1	636	642	PF00069	0.682
MOD_ProDKin_1	659	665	PF00069	0.786
MOD_ProDKin_1	71	77	PF00069	0.606
MOD_ProDKin_1	727	733	PF00069	0.595
MOD_ProDKin_1	739	745	PF00069	0.622
MOD_ProDKin_1	784	790	PF00069	0.676
MOD_ProDKin_1	82	88	PF00069	0.654
MOD_SUMO_rev_2	109	115	PF00179	0.533
MOD_SUMO_rev_2	472	482	PF00179	0.559
TRG_ENDOCYTIC_2	333	336	PF00928	0.596
TRG_ENDOCYTIC_2	761	764	PF00928	0.497
TRG_ER_diArg_1	197	199	PF00400	0.674
TRG_ER_diArg_1	345	347	PF00400	0.514
TRG_ER_diArg_1	542	545	PF00400	0.603
TRG_ER_diArg_1	546	548	PF00400	0.676
TRG_ER_diArg_1	62	64	PF00400	0.382
TRG_ER_diArg_1	676	679	PF00400	0.734
TRG_ER_diArg_1	810	812	PF00400	0.555

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P936	Leptomonas seymouri	29%	89%
A0A3S5H639	Leishmania donovani	75%	100%
A4H594	Leishmania braziliensis	46%	95%
A4HTH8	Leishmania infantum	75%	100%
Q4QIE2	Leishmania major	71%	95%