LeishMANIAdb
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Protein prickle

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Protein prickle
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AM91_LEIMU
TriTrypDb:
LmxM.08.0130
Length:
1152

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AM91
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AM91

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 240 244 PF00656 0.722
CLV_NRD_NRD_1 1013 1015 PF00675 0.811
CLV_NRD_NRD_1 1117 1119 PF00675 0.811
CLV_NRD_NRD_1 1132 1134 PF00675 0.576
CLV_NRD_NRD_1 220 222 PF00675 0.748
CLV_NRD_NRD_1 278 280 PF00675 0.730
CLV_NRD_NRD_1 411 413 PF00675 0.749
CLV_NRD_NRD_1 536 538 PF00675 0.734
CLV_NRD_NRD_1 561 563 PF00675 0.721
CLV_NRD_NRD_1 567 569 PF00675 0.769
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PFF5 Leptomonas seymouri 43% 97%
A0A3S7WQ38 Leishmania donovani 87% 100%
A4H580 Leishmania braziliensis 65% 100%
A4HTG3 Leishmania infantum 87% 100%
Q4QIF6 Leishmania major 85% 99%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS