FACT complex subunit

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

transcription factor-like protein

Species:

Leishmania mexicana

UniProt:

E9AM77_LEIMU

TriTrypDb:

LmxM.08_29.0020

Length:

1045

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0008023	transcription elongation factor complex	3	12
GO:0032991	protein-containing complex	1	12
GO:0035101	FACT complex	4	12
GO:0140513	nuclear protein-containing complex	2	12

Expansion

Sequence features

E9AM77

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AM77

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006260	DNA replication	5	12
GO:0006281	DNA repair	5	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006950	response to stress	2	12
GO:0006974	DNA damage response	4	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0033554	cellular response to stress	3	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0050896	response to stimulus	1	12
GO:0051716	cellular response to stimulus	2	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006325	chromatin organization	4	1
GO:0006354	DNA-templated transcription elongation	6	1
GO:0006355	regulation of DNA-templated transcription	6	1
GO:0006357	regulation of transcription by RNA polymerase II	7	1
GO:0006368	transcription elongation by RNA polymerase II	7	1
GO:0009058	biosynthetic process	2	1
GO:0009059	macromolecule biosynthetic process	4	1
GO:0009889	regulation of biosynthetic process	4	1
GO:0009891	positive regulation of biosynthetic process	5	1
GO:0009893	positive regulation of metabolic process	4	1
GO:0010468	regulation of gene expression	5	1
GO:0010556	regulation of macromolecule biosynthetic process	5	1
GO:0010557	positive regulation of macromolecule biosynthetic process	6	1
GO:0010604	positive regulation of macromolecule metabolic process	5	1
GO:0016043	cellular component organization	3	1
GO:0016070	RNA metabolic process	5	1
GO:0018130	heterocycle biosynthetic process	4	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0019438	aromatic compound biosynthetic process	4	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031325	positive regulation of cellular metabolic process	5	1
GO:0031326	regulation of cellular biosynthetic process	5	1
GO:0031328	positive regulation of cellular biosynthetic process	6	1
GO:0032774	RNA biosynthetic process	5	1
GO:0032784	regulation of DNA-templated transcription elongation	7	1
GO:0032786	positive regulation of DNA-templated transcription, elongation	8	1
GO:0032968	positive regulation of transcription elongation by RNA polymerase II	9	1
GO:0034243	regulation of transcription elongation by RNA polymerase II	8	1
GO:0034654	nucleobase-containing compound biosynthetic process	4	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0045893	positive regulation of DNA-templated transcription	7	1
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	6	1
GO:0045944	positive regulation of transcription by RNA polymerase II	8	1
GO:0048518	positive regulation of biological process	3	1
GO:0048522	positive regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051173	positive regulation of nitrogen compound metabolic process	5	1
GO:0051252	regulation of RNA metabolic process	5	1
GO:0051254	positive regulation of RNA metabolic process	6	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:1901362	organic cyclic compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1
GO:1902680	positive regulation of RNA biosynthetic process	7	1
GO:1903506	regulation of nucleic acid-templated transcription	7	1
GO:1903508	positive regulation of nucleic acid-templated transcription	8	1
GO:2001141	regulation of RNA biosynthetic process	6	1

Molecular functions
Term	Name	Level	Count
GO:0003682	chromatin binding	2	1
GO:0005488	binding	1	1
GO:0031491	nucleosome binding	3	1
GO:0044877	protein-containing complex binding	2	1
GO:0003824	catalytic activity	1	3
GO:0004177	aminopeptidase activity	5	3
GO:0008233	peptidase activity	3	3
GO:0008238	exopeptidase activity	4	3
GO:0016787	hydrolase activity	2	3
GO:0140096	catalytic activity, acting on a protein	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	932	936	PF00656	0.742
CLV_C14_Caspase3-7	946	950	PF00656	0.726
CLV_MEL_PAP_1	277	283	PF00089	0.425
CLV_NRD_NRD_1	1002	1004	PF00675	0.722
CLV_NRD_NRD_1	1043	1045	PF00675	0.662
CLV_NRD_NRD_1	190	192	PF00675	0.293
CLV_NRD_NRD_1	425	427	PF00675	0.378
CLV_NRD_NRD_1	450	452	PF00675	0.649
CLV_NRD_NRD_1	629	631	PF00675	0.268
CLV_NRD_NRD_1	725	727	PF00675	0.475
CLV_NRD_NRD_1	749	751	PF00675	0.513
CLV_NRD_NRD_1	983	985	PF00675	0.596
CLV_PCSK_KEX2_1	1004	1006	PF00082	0.760
CLV_PCSK_KEX2_1	1043	1045	PF00082	0.684
CLV_PCSK_KEX2_1	190	192	PF00082	0.286
CLV_PCSK_KEX2_1	203	205	PF00082	0.431
CLV_PCSK_KEX2_1	450	452	PF00082	0.704
CLV_PCSK_KEX2_1	631	633	PF00082	0.266
CLV_PCSK_KEX2_1	749	751	PF00082	0.629
CLV_PCSK_KEX2_1	983	985	PF00082	0.614
CLV_PCSK_PC1ET2_1	1004	1006	PF00082	0.760
CLV_PCSK_PC1ET2_1	203	205	PF00082	0.374
CLV_PCSK_PC1ET2_1	631	633	PF00082	0.338
CLV_PCSK_SKI1_1	213	217	PF00082	0.425
CLV_PCSK_SKI1_1	294	298	PF00082	0.425
CLV_PCSK_SKI1_1	388	392	PF00082	0.390
CLV_PCSK_SKI1_1	478	482	PF00082	0.425
CLV_PCSK_SKI1_1	606	610	PF00082	0.281
CLV_PCSK_SKI1_1	632	636	PF00082	0.326
CLV_PCSK_SKI1_1	727	731	PF00082	0.483
CLV_PCSK_SKI1_1	803	807	PF00082	0.430
CLV_PCSK_SKI1_1	812	816	PF00082	0.263
CLV_Separin_Metazoa	145	149	PF03568	0.520
DEG_APCC_DBOX_1	387	395	PF00400	0.305
DEG_APCC_DBOX_1	449	457	PF00400	0.634
DEG_APCC_DBOX_1	477	485	PF00400	0.533
DEG_APCC_DBOX_1	510	518	PF00400	0.550
DEG_APCC_DBOX_1	811	819	PF00400	0.477
DEG_APCC_DBOX_1	866	874	PF00400	0.477
DEG_Nend_UBRbox_3	1	3	PF02207	0.733
DEG_SCF_FBW7_1	818	825	PF00400	0.538
DEG_SCF_SKP2-CKS1_1	514	521	PF00560	0.555
DOC_CDC14_PxL_1	157	165	PF14671	0.478
DOC_CKS1_1	47	52	PF01111	0.564
DOC_CYCLIN_RxL_1	291	300	PF00134	0.425
DOC_CYCLIN_yCln2_LP_2	718	724	PF00134	0.475
DOC_MAPK_DCC_7	641	651	PF00069	0.513
DOC_MAPK_gen_1	541	548	PF00069	0.543
DOC_MAPK_gen_1	726	734	PF00069	0.399
DOC_MAPK_HePTP_8	850	862	PF00069	0.493
DOC_MAPK_MEF2A_6	1022	1030	PF00069	0.778
DOC_MAPK_MEF2A_6	541	548	PF00069	0.517
DOC_MAPK_MEF2A_6	571	578	PF00069	0.538
DOC_MAPK_MEF2A_6	726	734	PF00069	0.508
DOC_MAPK_MEF2A_6	853	862	PF00069	0.479
DOC_PP1_RVXF_1	539	546	PF00149	0.452
DOC_PP1_RVXF_1	697	704	PF00149	0.361
DOC_PP1_RVXF_1	810	817	PF00149	0.464
DOC_PP2B_LxvP_1	323	326	PF13499	0.452
DOC_PP2B_LxvP_1	649	652	PF13499	0.477
DOC_PP2B_PxIxI_1	857	863	PF00149	0.538
DOC_SPAK_OSR1_1	280	284	PF12202	0.452
DOC_USP7_MATH_1	150	154	PF00917	0.461
DOC_USP7_MATH_1	228	232	PF00917	0.452
DOC_USP7_MATH_1	301	305	PF00917	0.374
DOC_USP7_MATH_1	633	637	PF00917	0.507
DOC_USP7_MATH_1	706	710	PF00917	0.431
DOC_USP7_MATH_1	748	752	PF00917	0.603
DOC_USP7_MATH_1	866	870	PF00917	0.477
DOC_USP7_MATH_2	528	534	PF00917	0.353
DOC_USP7_UBL2_3	203	207	PF12436	0.362
DOC_USP7_UBL2_3	423	427	PF12436	0.393
DOC_USP7_UBL2_3	594	598	PF12436	0.452
DOC_USP7_UBL2_3	853	857	PF12436	0.477
DOC_WD40_RPTOR_TOS_1	403	409	PF00400	0.305
DOC_WW_Pin1_4	46	51	PF00397	0.455
DOC_WW_Pin1_4	515	520	PF00397	0.644
DOC_WW_Pin1_4	642	647	PF00397	0.493
DOC_WW_Pin1_4	686	691	PF00397	0.507
DOC_WW_Pin1_4	818	823	PF00397	0.531
LIG_14-3-3_CanoR_1	13	21	PF00244	0.503
LIG_14-3-3_CanoR_1	329	337	PF00244	0.405
LIG_14-3-3_CanoR_1	368	378	PF00244	0.390
LIG_14-3-3_CanoR_1	458	467	PF00244	0.567
LIG_14-3-3_CanoR_1	478	488	PF00244	0.237
LIG_14-3-3_CanoR_1	511	515	PF00244	0.590
LIG_14-3-3_CanoR_1	632	642	PF00244	0.464
LIG_14-3-3_CanoR_1	682	686	PF00244	0.508
LIG_14-3-3_CanoR_1	749	753	PF00244	0.521
LIG_14-3-3_CanoR_1	803	808	PF00244	0.512
LIG_14-3-3_CanoR_1	867	871	PF00244	0.413
LIG_14-3-3_CanoR_1	894	898	PF00244	0.569
LIG_Actin_WH2_2	667	684	PF00022	0.463
LIG_AP2alpha_2	907	909	PF02296	0.418
LIG_APCC_ABBA_1	270	275	PF00400	0.425
LIG_BRCT_BRCA1_1	352	356	PF00533	0.311
LIG_BRCT_BRCA1_1	532	536	PF00533	0.331
LIG_BRCT_BRCA1_1	842	846	PF00533	0.517
LIG_CaM_IQ_9	616	632	PF13499	0.513
LIG_Clathr_ClatBox_1	362	366	PF01394	0.305
LIG_CSL_BTD_1	544	547	PF09270	0.513
LIG_CtBP_PxDLS_1	1027	1031	PF00389	0.746
LIG_deltaCOP1_diTrp_1	902	909	PF00928	0.461
LIG_Dynein_DLC8_1	493	499	PF01221	0.606
LIG_EH1_1	209	217	PF00400	0.425
LIG_EH1_1	845	853	PF00400	0.538
LIG_EVH1_2	244	248	PF00568	0.425
LIG_FHA_1	100	106	PF00498	0.495
LIG_FHA_1	115	121	PF00498	0.357
LIG_FHA_1	142	148	PF00498	0.417
LIG_FHA_1	293	299	PF00498	0.324
LIG_FHA_1	358	364	PF00498	0.331
LIG_FHA_1	374	380	PF00498	0.233
LIG_FHA_1	406	412	PF00498	0.311
LIG_FHA_1	462	468	PF00498	0.670
LIG_FHA_1	571	577	PF00498	0.445
LIG_FHA_1	6	12	PF00498	0.416
LIG_FHA_1	651	657	PF00498	0.550
LIG_FHA_1	70	76	PF00498	0.460
LIG_FHA_1	79	85	PF00498	0.446
LIG_FHA_1	823	829	PF00498	0.463
LIG_FHA_2	206	212	PF00498	0.425
LIG_FHA_2	441	447	PF00498	0.504
LIG_FHA_2	497	503	PF00498	0.548
LIG_FHA_2	578	584	PF00498	0.349
LIG_FHA_2	687	693	PF00498	0.483
LIG_FHA_2	894	900	PF00498	0.486
LIG_FHA_2	920	926	PF00498	0.702
LIG_FHA_2	937	943	PF00498	0.507
LIG_FHA_2	94	100	PF00498	0.604
LIG_GBD_Chelix_1	424	432	PF00786	0.529
LIG_Integrin_isoDGR_2	639	641	PF01839	0.357
LIG_Integrin_RGD_1	27	29	PF01839	0.466
LIG_Integrin_RGD_1	911	913	PF01839	0.605
LIG_LIR_Apic_2	854	858	PF02991	0.477
LIG_LIR_Gen_1	141	151	PF02991	0.531
LIG_LIR_Gen_1	235	245	PF02991	0.427
LIG_LIR_Gen_1	286	296	PF02991	0.374
LIG_LIR_Gen_1	36	42	PF02991	0.408
LIG_LIR_Gen_1	430	441	PF02991	0.588
LIG_LIR_Gen_1	577	586	PF02991	0.452
LIG_LIR_Gen_1	692	703	PF02991	0.357
LIG_LIR_Gen_1	835	844	PF02991	0.519
LIG_LIR_Gen_1	913	921	PF02991	0.565
LIG_LIR_Gen_1	977	986	PF02991	0.583
LIG_LIR_Nem_3	141	146	PF02991	0.529
LIG_LIR_Nem_3	235	240	PF02991	0.427
LIG_LIR_Nem_3	286	291	PF02991	0.374
LIG_LIR_Nem_3	331	337	PF02991	0.343
LIG_LIR_Nem_3	36	41	PF02991	0.383
LIG_LIR_Nem_3	430	436	PF02991	0.518
LIG_LIR_Nem_3	692	698	PF02991	0.355
LIG_LIR_Nem_3	709	714	PF02991	0.336
LIG_LIR_Nem_3	796	800	PF02991	0.443
LIG_LIR_Nem_3	835	839	PF02991	0.505
LIG_LIR_Nem_3	913	918	PF02991	0.520
LIG_LIR_Nem_3	977	981	PF02991	0.644
LIG_NRBOX	162	168	PF00104	0.418
LIG_NRBOX	347	353	PF00104	0.374
LIG_NRBOX	476	482	PF00104	0.436
LIG_NRBOX	58	64	PF00104	0.413
LIG_PCNA_yPIPBox_3	113	123	PF02747	0.328
LIG_PCNA_yPIPBox_3	342	352	PF02747	0.407
LIG_Pex14_1	38	42	PF04695	0.462
LIG_Pex14_2	139	143	PF04695	0.479
LIG_PTB_Apo_2	282	289	PF02174	0.320
LIG_PTB_Phospho_1	282	288	PF10480	0.320
LIG_REV1ctd_RIR_1	289	298	PF16727	0.425
LIG_RPA_C_Fungi	22	34	PF08784	0.315
LIG_RPA_C_Fungi	8	20	PF08784	0.509
LIG_SH2_CRK	334	338	PF00017	0.360
LIG_SH2_CRK	855	859	PF00017	0.339
LIG_SH2_NCK_1	433	437	PF00017	0.349
LIG_SH2_SRC	433	436	PF00017	0.448
LIG_SH2_STAP1	288	292	PF00017	0.320
LIG_SH2_STAP1	314	318	PF00017	0.374
LIG_SH2_STAP1	572	576	PF00017	0.374
LIG_SH2_STAT3	253	256	PF00017	0.320
LIG_SH2_STAT5	288	291	PF00017	0.311
LIG_SH2_STAT5	572	575	PF00017	0.348
LIG_SH2_STAT5	61	64	PF00017	0.396
LIG_SH2_STAT5	711	714	PF00017	0.450
LIG_SH3_3	1009	1015	PF00018	0.691
LIG_SH3_3	122	128	PF00018	0.520
LIG_SH3_3	44	50	PF00018	0.573
LIG_SH3_3	516	522	PF00018	0.599
LIG_SH3_3	523	529	PF00018	0.597
LIG_SH3_3	541	547	PF00018	0.263
LIG_SH3_3	88	94	PF00018	0.500
LIG_SUMO_SIM_anti_2	102	107	PF11976	0.525
LIG_SUMO_SIM_anti_2	275	280	PF11976	0.321
LIG_SUMO_SIM_anti_2	359	366	PF11976	0.283
LIG_SUMO_SIM_anti_2	77	84	PF11976	0.415
LIG_SUMO_SIM_anti_2	830	835	PF11976	0.340
LIG_SUMO_SIM_par_1	101	107	PF11976	0.493
LIG_SUMO_SIM_par_1	294	300	PF11976	0.339
LIG_SUMO_SIM_par_1	359	366	PF11976	0.357
LIG_SUMO_SIM_par_1	416	422	PF11976	0.294
LIG_SUMO_SIM_par_1	462	468	PF11976	0.666
LIG_SUMO_SIM_par_1	7	12	PF11976	0.437
LIG_SUMO_SIM_par_1	858	864	PF11976	0.406
LIG_TRAF2_1	500	503	PF00917	0.573
LIG_TRAF2_1	580	583	PF00917	0.305
LIG_TRAF2_1	751	754	PF00917	0.487
LIG_TRAF2_1	779	782	PF00917	0.511
LIG_TRFH_1	588	592	PF08558	0.374
LIG_TYR_ITIM	431	436	PF00017	0.566
LIG_UBA3_1	694	699	PF00899	0.491
LIG_WRC_WIRS_1	773	778	PF05994	0.509
LIG_WRC_WIRS_1	833	838	PF05994	0.425
MOD_CDK_SPxK_1	515	521	PF00069	0.553
MOD_CK1_1	12	18	PF00069	0.441
MOD_CK1_1	141	147	PF00069	0.444
MOD_CK1_1	155	161	PF00069	0.341
MOD_CK1_1	238	244	PF00069	0.308
MOD_CK1_1	393	399	PF00069	0.385
MOD_CK1_1	454	460	PF00069	0.650
MOD_CK1_1	46	52	PF00069	0.538
MOD_CK1_1	936	942	PF00069	0.664
MOD_CK1_1	947	953	PF00069	0.673
MOD_CK1_1	961	967	PF00069	0.636
MOD_CK1_1	970	976	PF00069	0.618
MOD_CK2_1	440	446	PF00069	0.493
MOD_CK2_1	496	502	PF00069	0.632
MOD_CK2_1	510	516	PF00069	0.589
MOD_CK2_1	577	583	PF00069	0.219
MOD_CK2_1	748	754	PF00069	0.513
MOD_CK2_1	824	830	PF00069	0.396
MOD_CK2_1	893	899	PF00069	0.535
MOD_CK2_1	919	925	PF00069	0.673
MOD_CK2_1	93	99	PF00069	0.549
MOD_CK2_1	936	942	PF00069	0.509
MOD_CK2_1	951	957	PF00069	0.675
MOD_CK2_1	974	980	PF00069	0.679
MOD_CMANNOS	906	909	PF00535	0.444
MOD_Cter_Amidation	492	495	PF01082	0.522
MOD_GlcNHglycan	14	17	PF01048	0.371
MOD_GlcNHglycan	140	143	PF01048	0.491
MOD_GlcNHglycan	157	160	PF01048	0.389
MOD_GlcNHglycan	299	302	PF01048	0.425
MOD_GlcNHglycan	315	319	PF01048	0.382
MOD_GlcNHglycan	35	38	PF01048	0.429
MOD_GlcNHglycan	395	398	PF01048	0.391
MOD_GlcNHglycan	532	535	PF01048	0.346
MOD_GlcNHglycan	611	614	PF01048	0.440
MOD_GlcNHglycan	635	638	PF01048	0.368
MOD_GlcNHglycan	745	748	PF01048	0.609
MOD_GlcNHglycan	842	845	PF01048	0.374
MOD_GlcNHglycan	878	881	PF01048	0.398
MOD_GlcNHglycan	964	967	PF01048	0.720
MOD_GlcNHglycan	971	976	PF01048	0.662
MOD_GSK3_1	1	8	PF00069	0.585
MOD_GSK3_1	1017	1024	PF00069	0.750
MOD_GSK3_1	297	304	PF00069	0.416
MOD_GSK3_1	369	376	PF00069	0.392
MOD_GSK3_1	377	384	PF00069	0.317
MOD_GSK3_1	436	443	PF00069	0.643
MOD_GSK3_1	461	468	PF00069	0.683
MOD_GSK3_1	494	501	PF00069	0.566
MOD_GSK3_1	570	577	PF00069	0.317
MOD_GSK3_1	739	746	PF00069	0.534
MOD_GSK3_1	74	81	PF00069	0.409
MOD_GSK3_1	781	788	PF00069	0.472
MOD_GSK3_1	789	796	PF00069	0.501
MOD_GSK3_1	818	825	PF00069	0.393
MOD_GSK3_1	842	849	PF00069	0.388
MOD_GSK3_1	931	938	PF00069	0.688
MOD_GSK3_1	947	954	PF00069	0.602
MOD_GSK3_1	958	965	PF00069	0.598
MOD_GSK3_1	967	974	PF00069	0.681
MOD_LATS_1	801	807	PF00433	0.454
MOD_N-GLC_1	369	374	PF02516	0.257
MOD_N-GLC_1	5	10	PF02516	0.530
MOD_N-GLC_1	919	924	PF02516	0.695
MOD_NEK2_1	292	297	PF00069	0.398
MOD_NEK2_1	356	361	PF00069	0.320
MOD_NEK2_1	407	412	PF00069	0.320
MOD_NEK2_1	555	560	PF00069	0.305
MOD_NEK2_1	574	579	PF00069	0.121
MOD_NEK2_1	600	605	PF00069	0.343
MOD_NEK2_1	609	614	PF00069	0.248
MOD_NEK2_1	681	686	PF00069	0.376
MOD_NEK2_1	824	829	PF00069	0.366
MOD_NEK2_1	846	851	PF00069	0.362
MOD_NEK2_1	885	890	PF00069	0.412
MOD_NEK2_2	706	711	PF00069	0.433
MOD_NEK2_2	893	898	PF00069	0.561
MOD_PIKK_1	252	258	PF00454	0.425
MOD_PIKK_1	494	500	PF00454	0.630
MOD_PIKK_1	785	791	PF00454	0.454
MOD_PIKK_1	822	828	PF00454	0.339
MOD_PKA_1	494	500	PF00069	0.558
MOD_PKA_2	1021	1027	PF00069	0.746
MOD_PKA_2	114	120	PF00069	0.538
MOD_PKA_2	12	18	PF00069	0.468
MOD_PKA_2	328	334	PF00069	0.412
MOD_PKA_2	510	516	PF00069	0.584
MOD_PKA_2	640	646	PF00069	0.425
MOD_PKA_2	681	687	PF00069	0.370
MOD_PKA_2	748	754	PF00069	0.515
MOD_PKA_2	766	772	PF00069	0.350
MOD_PKA_2	866	872	PF00069	0.339
MOD_PKA_2	893	899	PF00069	0.565
MOD_PKB_1	630	638	PF00069	0.362
MOD_PKB_1	990	998	PF00069	0.715
MOD_Plk_1	235	241	PF00069	0.308
MOD_Plk_1	260	266	PF00069	0.452
MOD_Plk_1	399	405	PF00069	0.274
MOD_Plk_1	43	49	PF00069	0.561
MOD_Plk_1	5	11	PF00069	0.468
MOD_Plk_1	78	84	PF00069	0.469
MOD_Plk_1	846	852	PF00069	0.362
MOD_Plk_1	885	891	PF00069	0.393
MOD_Plk_1	936	942	PF00069	0.677
MOD_Plk_1	950	956	PF00069	0.614
MOD_Plk_2-3	205	211	PF00069	0.452
MOD_Plk_2-3	832	838	PF00069	0.320
MOD_Plk_2-3	945	951	PF00069	0.711
MOD_Plk_2-3	99	105	PF00069	0.503
MOD_Plk_4	152	158	PF00069	0.519
MOD_Plk_4	205	211	PF00069	0.419
MOD_Plk_4	381	387	PF00069	0.339
MOD_Plk_4	407	413	PF00069	0.425
MOD_Plk_4	461	467	PF00069	0.654
MOD_Plk_4	706	712	PF00069	0.489
MOD_Plk_4	78	84	PF00069	0.446
MOD_Plk_4	803	809	PF00069	0.374
MOD_Plk_4	846	852	PF00069	0.362
MOD_Plk_4	936	942	PF00069	0.695
MOD_Plk_4	951	957	PF00069	0.535
MOD_ProDKin_1	46	52	PF00069	0.452
MOD_ProDKin_1	515	521	PF00069	0.650
MOD_ProDKin_1	642	648	PF00069	0.362
MOD_ProDKin_1	686	692	PF00069	0.501
MOD_ProDKin_1	818	824	PF00069	0.415
MOD_SUMO_for_1	218	221	PF00179	0.374
MOD_SUMO_for_1	565	568	PF00179	0.281
MOD_SUMO_for_1	623	626	PF00179	0.425
MOD_SUMO_rev_2	200	209	PF00179	0.428
MOD_SUMO_rev_2	524	533	PF00179	0.618
MOD_SUMO_rev_2	558	567	PF00179	0.296
TRG_DiLeu_BaEn_1	347	352	PF01217	0.160
TRG_DiLeu_BaEn_1	476	481	PF01217	0.565
TRG_DiLeu_BaEn_1	78	83	PF01217	0.399
TRG_ENDOCYTIC_2	217	220	PF00928	0.425
TRG_ENDOCYTIC_2	288	291	PF00928	0.320
TRG_ENDOCYTIC_2	334	337	PF00928	0.360
TRG_ENDOCYTIC_2	433	436	PF00928	0.599
TRG_ER_diArg_1	1002	1005	PF00400	0.709
TRG_ER_diArg_1	1043	1045	PF00400	0.687
TRG_ER_diArg_1	189	191	PF00400	0.300
TRG_ER_diArg_1	449	451	PF00400	0.573
TRG_ER_diArg_1	764	767	PF00400	0.593
TRG_NES_CRM1_1	381	392	PF08389	0.317
TRG_NLS_MonoExtC_3	1002	1007	PF00514	0.704
TRG_NLS_MonoExtN_4	1002	1008	PF00514	0.685
TRG_Pf-PMV_PEXEL_1	294	299	PF00026	0.233
TRG_Pf-PMV_PEXEL_1	426	430	PF00026	0.425
TRG_Pf-PMV_PEXEL_1	478	483	PF00026	0.451
TRG_Pf-PMV_PEXEL_1	992	996	PF00026	0.467

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHS5	Leptomonas seymouri	75%	99%
A0A0S4JAR0	Bodo saltans	38%	100%
A0A1X0NZD4	Trypanosomatidae	54%	100%
A0A3S7X235	Leishmania donovani	95%	100%
A0A422NUY4	Trypanosoma rangeli	54%	100%
A4HH10	Leishmania braziliensis	85%	100%
A4I439	Leishmania infantum	95%	100%
C9ZKS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	100%
E9ADK4	Leishmania major	95%	100%
O82491	Arabidopsis thaliana	26%	97%
O94267	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
P0CQ22	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	28%	100%
P0CQ23	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	28%	100%
P32558	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
Q2UBF1	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	25%	100%
Q4HYB8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	24%	100%
Q4P2U5	Ustilago maydis (strain 521 / FGSC 9021)	26%	100%
Q4WJ02	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	24%	100%
Q54S43	Dictyostelium discoideum	25%	97%
Q5A1D5	Candida albicans (strain SC5314 / ATCC MYA-2876)	24%	99%
Q5B2X8	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	24%	100%
Q61E63	Caenorhabditis briggsae	27%	100%
Q6BXE5	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	26%	100%
Q6C931	Yarrowia lipolytica (strain CLIB 122 / E 150)	28%	100%
Q6FWT4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	100%
Q756A7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	27%	100%
Q7X923	Oryza sativa subsp. japonica	27%	99%
Q8H6B1	Zea mays	27%	99%
Q8IRG6	Drosophila melanogaster	26%	96%
Q8X0X6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	24%	100%
Q920B9	Mus musculus	27%	100%
Q9N5R9	Caenorhabditis elegans	28%	100%
Q9W603	Xenopus laevis	27%	100%
Q9Y5B9	Homo sapiens	27%	100%
V5DLC1	Trypanosoma cruzi	52%	100%