LeishMANIAdb
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BRCT domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
BRCT domain-containing protein
Gene product:
hypothetical protein
Species:
Leishmania mexicana
UniProt:
E9AM31_LEIMU
TriTrypDb:
LmxM.08_29.0480partial
Length:
249

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AM31
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AM31

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 30 34 PF00656 0.443
CLV_C14_Caspase3-7 77 81 PF00656 0.461
CLV_NRD_NRD_1 118 120 PF00675 0.459
CLV_NRD_NRD_1 137 139 PF00675 0.526
CLV_NRD_NRD_1 14 16 PF00675 0.478
CLV_NRD_NRD_1 206 208 PF00675 0.596
CLV_NRD_NRD_1 221 223 PF00675 0.534
CLV_NRD_NRD_1 237 239 PF00675 0.601
CLV_PCSK_FUR_1 235 239 PF00082 0.510
CLV_PCSK_KEX2_1 118 120 PF00082 0.448
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I7Y3 Leptomonas seymouri 55% 79%
A0A1X0NZJ3 Trypanosomatidae 41% 100%
A0A3S7X240 Leishmania donovani 86% 78%
A0A422NUJ3 Trypanosoma rangeli 40% 100%
A4HH49 Leishmania braziliensis 71% 100%
A4I4A0 Leishmania infantum 86% 78%
E9ADP9 Leishmania major 85% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS