DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

DNA helicase

Gene product:

tfiih basal transcription factor complex helicase xpb subunit

Species:

Leishmania mexicana

UniProt:

E9AM19_LEIMU

TriTrypDb:

LmxM.08_29.0590

Length:

1103

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0000109	nucleotide-excision repair complex	3	1
GO:0000112	nucleotide-excision repair factor 3 complex	4	1
GO:0005634	nucleus	5	1
GO:0005654	nucleoplasm	2	1
GO:0005667	transcription regulator complex	2	1
GO:0005675	transcription factor TFIIH holo complex	4	1
GO:0005737	cytoplasm	2	1
GO:0032806	carboxy-terminal domain protein kinase complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0032993	protein-DNA complex	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	1
GO:0090575	RNA polymerase II transcription regulator complex	3	1
GO:0097550	transcription preinitiation complex	3	1
GO:0110165	cellular anatomical entity	1	1
GO:0140513	nuclear protein-containing complex	2	1
GO:1902494	catalytic complex	2	1
GO:1902554	serine/threonine protein kinase complex	6	1
GO:1902911	protein kinase complex	5	1
GO:1990234	transferase complex	3	1

Expansion

Sequence features

E9AM19

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AM19

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	5
GO:0006352	DNA-templated transcription initiation	6	5
GO:0006367	transcription initiation at RNA polymerase II promoter	7	5
GO:0006725	cellular aromatic compound metabolic process	3	5
GO:0006807	nitrogen compound metabolic process	2	5
GO:0008152	metabolic process	1	5
GO:0009058	biosynthetic process	2	5
GO:0009059	macromolecule biosynthetic process	4	5
GO:0009987	cellular process	1	5
GO:0016070	RNA metabolic process	5	5
GO:0018130	heterocycle biosynthetic process	4	5
GO:0019438	aromatic compound biosynthetic process	4	5
GO:0032774	RNA biosynthetic process	5	5
GO:0033683	obsolete nucleotide-excision repair, DNA incision	6	1
GO:0034641	cellular nitrogen compound metabolic process	3	5
GO:0034654	nucleobase-containing compound biosynthetic process	4	5
GO:0043170	macromolecule metabolic process	3	5
GO:0044237	cellular metabolic process	2	5
GO:0044238	primary metabolic process	2	5
GO:0044249	cellular biosynthetic process	3	5
GO:0044271	cellular nitrogen compound biosynthetic process	4	5
GO:0046483	heterocycle metabolic process	3	5
GO:0071704	organic substance metabolic process	2	5
GO:0090304	nucleic acid metabolic process	4	5
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5	1
GO:1901360	organic cyclic compound metabolic process	3	5
GO:1901362	organic cyclic compound biosynthetic process	4	5
GO:1901576	organic substance biosynthetic process	3	5
GO:0006259	DNA metabolic process	4	4
GO:0006281	DNA repair	5	4
GO:0006289	nucleotide-excision repair	6	4
GO:0006950	response to stress	2	4
GO:0006974	DNA damage response	4	4
GO:0033554	cellular response to stress	3	4
GO:0044260	obsolete cellular macromolecule metabolic process	3	4
GO:0050896	response to stimulus	1	4
GO:0051716	cellular response to stimulus	2	4

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	13
GO:0003676	nucleic acid binding	3	13
GO:0003677	DNA binding	4	13
GO:0003678	DNA helicase activity	3	13
GO:0003824	catalytic activity	1	13
GO:0004386	helicase activity	2	13
GO:0005488	binding	1	13
GO:0005524	ATP binding	5	13
GO:0008094	ATP-dependent activity, acting on DNA	2	13
GO:0016787	hydrolase activity	2	13
GO:0017076	purine nucleotide binding	4	13
GO:0030554	adenyl nucleotide binding	5	13
GO:0032553	ribonucleotide binding	3	13
GO:0032555	purine ribonucleotide binding	4	13
GO:0032559	adenyl ribonucleotide binding	5	13
GO:0035639	purine ribonucleoside triphosphate binding	4	13
GO:0036094	small molecule binding	2	13
GO:0043167	ion binding	2	13
GO:0043168	anion binding	3	13
GO:0097159	organic cyclic compound binding	2	13
GO:0097367	carbohydrate derivative binding	2	13
GO:0140097	catalytic activity, acting on DNA	3	13
GO:0140640	catalytic activity, acting on a nucleic acid	2	13
GO:0140657	ATP-dependent activity	1	13
GO:1901265	nucleoside phosphate binding	3	13
GO:1901363	heterocyclic compound binding	2	13
GO:0003700	DNA-binding transcription factor activity	2	1
GO:0043138	3'-5' DNA helicase activity	4	1
GO:0140110	transcription regulator activity	1	1
GO:0016462	pyrophosphatase activity	5	2
GO:0016817	hydrolase activity, acting on acid anhydrides	3	2
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	2
GO:0016887	ATP hydrolysis activity	7	2
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1030	1034	PF00656	0.561
CLV_C14_Caspase3-7	187	191	PF00656	0.717
CLV_C14_Caspase3-7	727	731	PF00656	0.629
CLV_MEL_PAP_1	834	840	PF00089	0.292
CLV_NRD_NRD_1	1055	1057	PF00675	0.421
CLV_NRD_NRD_1	1058	1060	PF00675	0.433
CLV_NRD_NRD_1	293	295	PF00675	0.598
CLV_NRD_NRD_1	491	493	PF00675	0.393
CLV_NRD_NRD_1	707	709	PF00675	0.716
CLV_NRD_NRD_1	714	716	PF00675	0.691
CLV_NRD_NRD_1	741	743	PF00675	0.558
CLV_NRD_NRD_1	861	863	PF00675	0.343
CLV_PCSK_FUR_1	1053	1057	PF00082	0.576
CLV_PCSK_FUR_1	489	493	PF00082	0.330
CLV_PCSK_KEX2_1	1055	1057	PF00082	0.421
CLV_PCSK_KEX2_1	1058	1060	PF00082	0.433
CLV_PCSK_KEX2_1	173	175	PF00082	0.739
CLV_PCSK_KEX2_1	293	295	PF00082	0.607
CLV_PCSK_KEX2_1	491	493	PF00082	0.370
CLV_PCSK_KEX2_1	577	579	PF00082	0.310
CLV_PCSK_KEX2_1	707	709	PF00082	0.717
CLV_PCSK_KEX2_1	712	714	PF00082	0.712
CLV_PCSK_KEX2_1	741	743	PF00082	0.558
CLV_PCSK_KEX2_1	861	863	PF00082	0.343
CLV_PCSK_KEX2_1	902	904	PF00082	0.422
CLV_PCSK_PC1ET2_1	173	175	PF00082	0.739
CLV_PCSK_PC1ET2_1	577	579	PF00082	0.370
CLV_PCSK_PC1ET2_1	712	714	PF00082	0.649
CLV_PCSK_PC1ET2_1	902	904	PF00082	0.422
CLV_PCSK_PC7_1	703	709	PF00082	0.466
CLV_PCSK_SKI1_1	219	223	PF00082	0.599
CLV_PCSK_SKI1_1	357	361	PF00082	0.491
CLV_PCSK_SKI1_1	370	374	PF00082	0.325
CLV_PCSK_SKI1_1	440	444	PF00082	0.419
CLV_PCSK_SKI1_1	509	513	PF00082	0.343
CLV_PCSK_SKI1_1	539	543	PF00082	0.310
CLV_PCSK_SKI1_1	590	594	PF00082	0.370
CLV_PCSK_SKI1_1	627	631	PF00082	0.422
CLV_PCSK_SKI1_1	695	699	PF00082	0.546
CLV_Separin_Metazoa	408	412	PF03568	0.502
DEG_APCC_DBOX_1	345	353	PF00400	0.500
DEG_APCC_DBOX_1	369	377	PF00400	0.510
DEG_APCC_DBOX_1	589	597	PF00400	0.422
DEG_COP1_1	151	161	PF00400	0.495
DEG_Nend_UBRbox_3	1	3	PF02207	0.517
DEG_SCF_FBW7_1	158	164	PF00400	0.494
DEG_SPOP_SBC_1	205	209	PF00917	0.479
DOC_ANK_TNKS_1	577	584	PF00023	0.271
DOC_CDC14_PxL_1	1014	1022	PF14671	0.553
DOC_CKS1_1	158	163	PF01111	0.495
DOC_CKS1_1	222	227	PF01111	0.596
DOC_CYCLIN_RxL_1	213	224	PF00134	0.684
DOC_CYCLIN_RxL_1	752	761	PF00134	0.338
DOC_CYCLIN_RxL_1	870	882	PF00134	0.180
DOC_CYCLIN_yCln2_LP_2	217	223	PF00134	0.669
DOC_MAPK_DCC_7	357	365	PF00069	0.456
DOC_MAPK_DCC_7	464	473	PF00069	0.388
DOC_MAPK_DCC_7	870	879	PF00069	0.180
DOC_MAPK_gen_1	1081	1090	PF00069	0.503
DOC_MAPK_gen_1	491	502	PF00069	0.369
DOC_MAPK_gen_1	560	568	PF00069	0.422
DOC_MAPK_gen_1	625	632	PF00069	0.317
DOC_MAPK_gen_1	870	879	PF00069	0.180
DOC_MAPK_JIP1_4	399	405	PF00069	0.671
DOC_MAPK_MEF2A_6	250	257	PF00069	0.647
DOC_MAPK_MEF2A_6	464	473	PF00069	0.388
DOC_MAPK_MEF2A_6	837	845	PF00069	0.343
DOC_PP1_RVXF_1	1024	1030	PF00149	0.537
DOC_PP1_RVXF_1	1076	1083	PF00149	0.384
DOC_PP1_RVXF_1	783	790	PF00149	0.296
DOC_PP2B_LxvP_1	466	469	PF13499	0.451
DOC_PP2B_LxvP_1	803	806	PF13499	0.343
DOC_PP2B_LxvP_1	843	846	PF13499	0.292
DOC_PP4_FxxP_1	359	362	PF00568	0.400
DOC_USP7_MATH_1	1007	1011	PF00917	0.560
DOC_USP7_MATH_1	161	165	PF00917	0.744
DOC_USP7_MATH_1	191	195	PF00917	0.743
DOC_USP7_MATH_1	204	208	PF00917	0.693
DOC_USP7_MATH_1	315	319	PF00917	0.789
DOC_USP7_MATH_1	421	425	PF00917	0.701
DOC_USP7_MATH_1	586	590	PF00917	0.419
DOC_USP7_MATH_1	751	755	PF00917	0.478
DOC_USP7_MATH_1	846	850	PF00917	0.292
DOC_USP7_MATH_1	895	899	PF00917	0.338
DOC_USP7_MATH_1	951	955	PF00917	0.661
DOC_USP7_UBL2_3	169	173	PF12436	0.762
DOC_WW_Pin1_4	1003	1008	PF00397	0.509
DOC_WW_Pin1_4	1047	1052	PF00397	0.503
DOC_WW_Pin1_4	152	157	PF00397	0.645
DOC_WW_Pin1_4	206	211	PF00397	0.633
DOC_WW_Pin1_4	221	226	PF00397	0.525
DOC_WW_Pin1_4	231	236	PF00397	0.725
DOC_WW_Pin1_4	309	314	PF00397	0.703
DOC_WW_Pin1_4	376	381	PF00397	0.663
DOC_WW_Pin1_4	419	424	PF00397	0.670
DOC_WW_Pin1_4	778	783	PF00397	0.290
DOC_WW_Pin1_4	949	954	PF00397	0.670
LIG_14-3-3_CanoR_1	105	113	PF00244	0.616
LIG_14-3-3_CanoR_1	1084	1088	PF00244	0.603
LIG_14-3-3_CanoR_1	167	172	PF00244	0.502
LIG_14-3-3_CanoR_1	250	256	PF00244	0.678
LIG_14-3-3_CanoR_1	302	307	PF00244	0.727
LIG_14-3-3_CanoR_1	314	318	PF00244	0.784
LIG_14-3-3_CanoR_1	370	380	PF00244	0.489
LIG_14-3-3_CanoR_1	758	767	PF00244	0.372
LIG_14-3-3_CanoR_1	903	907	PF00244	0.307
LIG_14-3-3_CanoR_1	921	929	PF00244	0.327
LIG_14-3-3_CanoR_1	992	998	PF00244	0.594
LIG_APCC_ABBA_1	786	791	PF00400	0.293
LIG_APCC_ABBAyCdc20_2	715	721	PF00400	0.658
LIG_APCC_ABBAyCdc20_2	785	791	PF00400	0.292
LIG_BRCT_BRCA1_1	118	122	PF00533	0.629
LIG_Clathr_ClatBox_1	603	607	PF01394	0.362
LIG_deltaCOP1_diTrp_1	1023	1029	PF00928	0.424
LIG_FHA_1	1038	1044	PF00498	0.495
LIG_FHA_1	136	142	PF00498	0.710
LIG_FHA_1	158	164	PF00498	0.723
LIG_FHA_1	209	215	PF00498	0.642
LIG_FHA_1	324	330	PF00498	0.702
LIG_FHA_1	382	388	PF00498	0.617
LIG_FHA_1	463	469	PF00498	0.448
LIG_FHA_1	520	526	PF00498	0.455
LIG_FHA_1	54	60	PF00498	0.479
LIG_FHA_1	554	560	PF00498	0.439
LIG_FHA_1	692	698	PF00498	0.510
LIG_FHA_1	768	774	PF00498	0.293
LIG_FHA_1	816	822	PF00498	0.389
LIG_FHA_1	892	898	PF00498	0.346
LIG_FHA_1	955	961	PF00498	0.649
LIG_FHA_1	992	998	PF00498	0.550
LIG_FHA_2	106	112	PF00498	0.700
LIG_FHA_2	412	418	PF00498	0.709
LIG_IBAR_NPY_1	763	765	PF08397	0.310
LIG_LIR_Apic_2	358	362	PF02991	0.411
LIG_LIR_Apic_2	969	975	PF02991	0.534
LIG_LIR_Gen_1	1028	1035	PF02991	0.482
LIG_LIR_Gen_1	444	454	PF02991	0.463
LIG_LIR_Gen_1	455	466	PF02991	0.331
LIG_LIR_Gen_1	569	576	PF02991	0.343
LIG_LIR_Gen_1	656	667	PF02991	0.395
LIG_LIR_Gen_1	686	696	PF02991	0.349
LIG_LIR_Gen_1	924	933	PF02991	0.535
LIG_LIR_Nem_3	1028	1032	PF02991	0.478
LIG_LIR_Nem_3	1037	1041	PF02991	0.397
LIG_LIR_Nem_3	444	450	PF02991	0.419
LIG_LIR_Nem_3	455	460	PF02991	0.353
LIG_LIR_Nem_3	569	574	PF02991	0.343
LIG_LIR_Nem_3	623	629	PF02991	0.338
LIG_LIR_Nem_3	656	662	PF02991	0.381
LIG_LIR_Nem_3	686	691	PF02991	0.422
LIG_LIR_Nem_3	924	929	PF02991	0.504
LIG_LYPXL_SIV_4	17	25	PF13949	0.509
LIG_LYPXL_yS_3	1017	1020	PF13949	0.554
LIG_PCNA_yPIPBox_3	165	174	PF02747	0.554
LIG_Pex14_1	1025	1029	PF04695	0.465
LIG_Pex14_1	537	541	PF04695	0.292
LIG_Rb_LxCxE_1	23	39	PF01857	0.434
LIG_SH2_CRK	571	575	PF00017	0.343
LIG_SH2_CRK	626	630	PF00017	0.335
LIG_SH2_CRK	688	692	PF00017	0.261
LIG_SH2_CRK	887	891	PF00017	0.343
LIG_SH2_CRK	914	918	PF00017	0.310
LIG_SH2_CRK	968	972	PF00017	0.411
LIG_SH2_NCK_1	416	420	PF00017	0.515
LIG_SH2_NCK_1	887	891	PF00017	0.343
LIG_SH2_SRC	18	21	PF00017	0.449
LIG_SH2_SRC	407	410	PF00017	0.662
LIG_SH2_STAP1	18	22	PF00017	0.517
LIG_SH2_STAP1	416	420	PF00017	0.458
LIG_SH2_STAP1	57	61	PF00017	0.434
LIG_SH2_STAP1	571	575	PF00017	0.416
LIG_SH2_STAP1	655	659	PF00017	0.402
LIG_SH2_STAT3	339	342	PF00017	0.538
LIG_SH2_STAT3	901	904	PF00017	0.310
LIG_SH2_STAT5	339	342	PF00017	0.407
LIG_SH2_STAT5	792	795	PF00017	0.422
LIG_SH2_STAT5	823	826	PF00017	0.292
LIG_SH2_STAT5	885	888	PF00017	0.293
LIG_SH3_2	1048	1053	PF14604	0.497
LIG_SH3_3	1029	1035	PF00018	0.491
LIG_SH3_3	1045	1051	PF00018	0.512
LIG_SH3_3	150	156	PF00018	0.559
LIG_SH3_3	217	223	PF00018	0.722
LIG_SH3_3	254	260	PF00018	0.660
LIG_SH3_3	284	290	PF00018	0.461
LIG_SH3_3	498	504	PF00018	0.229
LIG_SH3_3	673	679	PF00018	0.408
LIG_SH3_3	933	939	PF00018	0.387
LIG_Sin3_3	980	987	PF02671	0.423
LIG_SUMO_SIM_anti_2	254	259	PF11976	0.628
LIG_SUMO_SIM_par_1	1039	1045	PF11976	0.623
LIG_SUMO_SIM_par_1	602	608	PF11976	0.343
LIG_SUMO_SIM_par_1	76	82	PF11976	0.471
LIG_SUMO_SIM_par_1	875	880	PF11976	0.428
LIG_TRAF2_1	1010	1013	PF00917	0.671
LIG_TRAF2_1	1073	1076	PF00917	0.518
LIG_TRAF2_1	108	111	PF00917	0.766
LIG_TRAF2_1	585	588	PF00917	0.404
LIG_TRAF2_1	73	76	PF00917	0.531
LIG_TRAF2_1	93	96	PF00917	0.388
LIG_TYR_ITIM	624	629	PF00017	0.335
LIG_TYR_ITIM	966	971	PF00017	0.559
LIG_TYR_ITSM	567	574	PF00017	0.422
LIG_UBA3_1	270	276	PF00899	0.360
LIG_WW_3	408	412	PF00397	0.502
MOD_CDC14_SPxK_1	1050	1053	PF00782	0.481
MOD_CDK_SPK_2	309	314	PF00069	0.491
MOD_CDK_SPxK_1	1047	1053	PF00069	0.497
MOD_CDK_SPxxK_3	206	213	PF00069	0.701
MOD_CDK_SPxxK_3	778	785	PF00069	0.292
MOD_CK1_1	1021	1027	PF00069	0.601
MOD_CK1_1	106	112	PF00069	0.753
MOD_CK1_1	118	124	PF00069	0.444
MOD_CK1_1	200	206	PF00069	0.722
MOD_CK1_1	208	214	PF00069	0.670
MOD_CK1_1	234	240	PF00069	0.666
MOD_CK1_1	305	311	PF00069	0.792
MOD_CK1_1	46	52	PF00069	0.434
MOD_CK1_1	891	897	PF00069	0.351
MOD_CK1_1	954	960	PF00069	0.631
MOD_CK2_1	1007	1013	PF00069	0.544
MOD_CK2_1	105	111	PF00069	0.533
MOD_CK2_1	1097	1103	PF00069	0.624
MOD_CK2_1	191	197	PF00069	0.590
MOD_CK2_1	236	242	PF00069	0.734
MOD_CK2_1	24	30	PF00069	0.396
MOD_CK2_1	385	391	PF00069	0.475
MOD_CK2_1	411	417	PF00069	0.702
MOD_CK2_1	810	816	PF00069	0.310
MOD_CK2_1	89	95	PF00069	0.405
MOD_Cter_Amidation	710	713	PF01082	0.619
MOD_Cter_Amidation	739	742	PF01082	0.502
MOD_GlcNHglycan	1095	1098	PF01048	0.539
MOD_GlcNHglycan	148	151	PF01048	0.738
MOD_GlcNHglycan	186	189	PF01048	0.725
MOD_GlcNHglycan	193	196	PF01048	0.667
MOD_GlcNHglycan	226	229	PF01048	0.685
MOD_GlcNHglycan	423	426	PF01048	0.612
MOD_GlcNHglycan	48	51	PF01048	0.399
MOD_GlcNHglycan	5	8	PF01048	0.538
MOD_GlcNHglycan	632	635	PF01048	0.292
MOD_GlcNHglycan	827	830	PF01048	0.180
MOD_GlcNHglycan	854	857	PF01048	0.310
MOD_GlcNHglycan	91	94	PF01048	0.651
MOD_GlcNHglycan	949	952	PF01048	0.635
MOD_GlcNHglycan	976	979	PF01048	0.485
MOD_GSK3_1	1003	1010	PF00069	0.549
MOD_GSK3_1	1021	1028	PF00069	0.492
MOD_GSK3_1	1093	1100	PF00069	0.626
MOD_GSK3_1	112	119	PF00069	0.774
MOD_GSK3_1	137	144	PF00069	0.691
MOD_GSK3_1	157	164	PF00069	0.616
MOD_GSK3_1	191	198	PF00069	0.670
MOD_GSK3_1	200	207	PF00069	0.610
MOD_GSK3_1	298	305	PF00069	0.676
MOD_GSK3_1	309	316	PF00069	0.749
MOD_GSK3_1	381	388	PF00069	0.469
MOD_GSK3_1	419	426	PF00069	0.683
MOD_GSK3_1	42	49	PF00069	0.462
MOD_GSK3_1	516	523	PF00069	0.338
MOD_GSK3_1	875	882	PF00069	0.303
MOD_GSK3_1	891	898	PF00069	0.328
MOD_GSK3_1	945	952	PF00069	0.663
MOD_GSK3_1	993	1000	PF00069	0.553
MOD_N-GLC_1	279	284	PF02516	0.443
MOD_N-GLC_1	530	535	PF02516	0.350
MOD_N-GLC_2	881	883	PF02516	0.310
MOD_NEK2_1	1062	1067	PF00069	0.598
MOD_NEK2_1	137	142	PF00069	0.686
MOD_NEK2_1	24	29	PF00069	0.393
MOD_NEK2_1	298	303	PF00069	0.732
MOD_NEK2_1	306	311	PF00069	0.780
MOD_NEK2_1	340	345	PF00069	0.516
MOD_NEK2_1	381	386	PF00069	0.752
MOD_NEK2_1	43	48	PF00069	0.430
MOD_NEK2_1	520	525	PF00069	0.348
MOD_NEK2_1	567	572	PF00069	0.330
MOD_NEK2_1	630	635	PF00069	0.318
MOD_NEK2_1	660	665	PF00069	0.373
MOD_NEK2_1	767	772	PF00069	0.322
MOD_NEK2_1	824	829	PF00069	0.452
MOD_NEK2_1	857	862	PF00069	0.280
MOD_NEK2_1	879	884	PF00069	0.335
MOD_NEK2_1	945	950	PF00069	0.616
MOD_NEK2_2	423	428	PF00069	0.402
MOD_NEK2_2	993	998	PF00069	0.368
MOD_PIKK_1	106	112	PF00454	0.757
MOD_PIKK_1	236	242	PF00454	0.597
MOD_PIKK_1	32	38	PF00454	0.459
MOD_PIKK_1	767	773	PF00454	0.303
MOD_PIKK_1	888	894	PF00454	0.310
MOD_PK_1	714	720	PF00069	0.647
MOD_PKA_1	714	720	PF00069	0.647
MOD_PKA_1	902	908	PF00069	0.422
MOD_PKA_2	106	112	PF00069	0.800
MOD_PKA_2	1083	1089	PF00069	0.562
MOD_PKA_2	1090	1096	PF00069	0.662
MOD_PKA_2	184	190	PF00069	0.770
MOD_PKA_2	313	319	PF00069	0.794
MOD_PKA_2	542	548	PF00069	0.292
MOD_PKA_2	714	720	PF00069	0.739
MOD_PKA_2	810	816	PF00069	0.421
MOD_PKA_2	902	908	PF00069	0.316
MOD_PKA_2	991	997	PF00069	0.538
MOD_Plk_1	279	285	PF00069	0.438
MOD_Plk_1	43	49	PF00069	0.498
MOD_Plk_1	462	468	PF00069	0.497
MOD_Plk_1	530	536	PF00069	0.396
MOD_Plk_1	550	556	PF00069	0.214
MOD_Plk_2-3	723	729	PF00069	0.596
MOD_Plk_4	1037	1043	PF00069	0.594
MOD_Plk_4	1083	1089	PF00069	0.531
MOD_Plk_4	137	143	PF00069	0.646
MOD_Plk_4	167	173	PF00069	0.779
MOD_Plk_4	521	527	PF00069	0.327
MOD_Plk_4	530	536	PF00069	0.308
MOD_Plk_4	569	575	PF00069	0.386
MOD_Plk_4	632	638	PF00069	0.343
MOD_Plk_4	714	720	PF00069	0.739
MOD_Plk_4	846	852	PF00069	0.307
MOD_Plk_4	885	891	PF00069	0.354
MOD_Plk_4	902	908	PF00069	0.229
MOD_ProDKin_1	1003	1009	PF00069	0.502
MOD_ProDKin_1	1047	1053	PF00069	0.497
MOD_ProDKin_1	152	158	PF00069	0.648
MOD_ProDKin_1	206	212	PF00069	0.627
MOD_ProDKin_1	221	227	PF00069	0.528
MOD_ProDKin_1	231	237	PF00069	0.726
MOD_ProDKin_1	309	315	PF00069	0.703
MOD_ProDKin_1	376	382	PF00069	0.667
MOD_ProDKin_1	419	425	PF00069	0.667
MOD_ProDKin_1	778	784	PF00069	0.290
MOD_ProDKin_1	949	955	PF00069	0.672
MOD_SUMO_for_1	172	175	PF00179	0.715
MOD_SUMO_for_1	275	278	PF00179	0.434
MOD_SUMO_rev_2	377	387	PF00179	0.524
MOD_SUMO_rev_2	639	643	PF00179	0.466
TRG_DiLeu_BaEn_1	816	821	PF01217	0.298
TRG_DiLeu_BaEn_3	587	593	PF01217	0.422
TRG_DiLeu_BaLyEn_6	1015	1020	PF01217	0.717
TRG_DiLeu_BaLyEn_6	210	215	PF01217	0.541
TRG_DiLeu_BaLyEn_6	217	222	PF01217	0.484
TRG_DiLeu_BaLyEn_6	248	253	PF01217	0.661
TRG_DiLeu_BaLyEn_6	401	406	PF01217	0.586
TRG_ENDOCYTIC_2	1017	1020	PF00928	0.554
TRG_ENDOCYTIC_2	18	21	PF00928	0.410
TRG_ENDOCYTIC_2	458	461	PF00928	0.389
TRG_ENDOCYTIC_2	571	574	PF00928	0.343
TRG_ENDOCYTIC_2	626	629	PF00928	0.335
TRG_ENDOCYTIC_2	688	691	PF00928	0.458
TRG_ENDOCYTIC_2	887	890	PF00928	0.343
TRG_ENDOCYTIC_2	914	917	PF00928	0.332
TRG_ENDOCYTIC_2	968	971	PF00928	0.575
TRG_ER_diArg_1	1055	1058	PF00400	0.429
TRG_ER_diArg_1	292	294	PF00400	0.451
TRG_ER_diArg_1	477	480	PF00400	0.339
TRG_ER_diArg_1	490	492	PF00400	0.353
TRG_ER_diArg_1	713	715	PF00400	0.646
TRG_ER_diArg_1	741	744	PF00400	0.522
TRG_Pf-PMV_PEXEL_1	130	134	PF00026	0.599
TRG_Pf-PMV_PEXEL_1	265	269	PF00026	0.529
TRG_Pf-PMV_PEXEL_1	404	408	PF00026	0.594
TRG_Pf-PMV_PEXEL_1	590	594	PF00026	0.338
TRG_Pf-PMV_PEXEL_1	915	920	PF00026	0.296
TRG_Pf-PMV_PEXEL_1	921	925	PF00026	0.367

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM24	Leptomonas seymouri	64%	100%
A0A0S4JHE3	Bodo saltans	40%	100%
A0A1X0P056	Trypanosomatidae	53%	100%
A0A3S5H7K7	Leishmania donovani	91%	100%
A0A3S5IRW5	Trypanosoma rangeli	47%	100%
A0A3S7X6B2	Leishmania donovani	30%	100%
A4HH67	Leishmania braziliensis	82%	100%
A4I4B1	Leishmania infantum	91%	100%
A4I8L0	Leishmania infantum	30%	100%
C9ZKL6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
E9ADR1	Leishmania major	91%	100%
Q580W5	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	52%	100%