Putative A-1 protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

A-1 protein, putative

Species:

Leishmania mexicana

UniProt:

E9ALX9_LEIMU

TriTrypDb:

LmxM.08_29.0935

Length:

175

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ALX9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALX9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	77	81	PF00656	0.511
CLV_NRD_NRD_1	154	156	PF00675	0.564
CLV_NRD_NRD_1	4	6	PF00675	0.769
CLV_PCSK_KEX2_1	6	8	PF00082	0.757
CLV_PCSK_KEX2_1	64	66	PF00082	0.555
CLV_PCSK_PC1ET2_1	6	8	PF00082	0.672
CLV_PCSK_PC1ET2_1	64	66	PF00082	0.555
CLV_PCSK_SKI1_1	156	160	PF00082	0.549
CLV_PCSK_SKI1_1	76	80	PF00082	0.630
CLV_PCSK_SKI1_1	92	96	PF00082	0.493
DEG_Nend_UBRbox_2	1	3	PF02207	0.688
DEG_SPOP_SBC_1	44	48	PF00917	0.601
DOC_CYCLIN_RxL_1	153	162	PF00134	0.551
DOC_PP2B_LxvP_1	121	124	PF13499	0.615
DOC_USP7_MATH_1	137	141	PF00917	0.588
DOC_USP7_MATH_1	44	48	PF00917	0.557
DOC_WW_Pin1_4	45	50	PF00397	0.603
LIG_14-3-3_CanoR_1	65	73	PF00244	0.554
LIG_Dynein_DLC8_1	140	146	PF01221	0.657
LIG_FHA_1	116	122	PF00498	0.483
LIG_FHA_1	65	71	PF00498	0.504
LIG_FHA_2	142	148	PF00498	0.649
LIG_FHA_2	46	52	PF00498	0.637
LIG_FHA_2	88	94	PF00498	0.651
LIG_LIR_Gen_1	164	174	PF02991	0.527
LIG_LIR_Gen_1	56	63	PF02991	0.621
LIG_LIR_LC3C_4	118	123	PF02991	0.441
LIG_LIR_Nem_3	164	170	PF02991	0.520
LIG_LIR_Nem_3	56	62	PF02991	0.626
LIG_NRBOX	165	171	PF00104	0.521
LIG_SH2_CRK	167	171	PF00017	0.521
LIG_SH2_CRK	59	63	PF00017	0.564
LIG_SH2_STAP1	59	63	PF00017	0.564
LIG_SH2_STAT5	167	170	PF00017	0.520
LIG_SxIP_EBH_1	40	49	PF03271	0.598
LIG_TRAF2_1	48	51	PF00917	0.604
LIG_TRAF2_1	83	86	PF00917	0.626
MOD_CK1_1	115	121	PF00069	0.590
MOD_CK1_1	148	154	PF00069	0.556
MOD_CK2_1	141	147	PF00069	0.655
MOD_CK2_1	44	50	PF00069	0.646
MOD_CK2_1	8	14	PF00069	0.573
MOD_CK2_1	87	93	PF00069	0.650
MOD_GlcNHglycan	10	13	PF01048	0.675
MOD_GlcNHglycan	20	26	PF01048	0.723
MOD_GlcNHglycan	40	43	PF01048	0.634
MOD_GSK3_1	137	144	PF00069	0.624
MOD_GSK3_1	161	168	PF00069	0.465
MOD_GSK3_1	50	57	PF00069	0.587
MOD_GSK3_1	92	99	PF00069	0.647
MOD_PIKK_1	141	147	PF00454	0.655
MOD_PIKK_1	87	93	PF00454	0.651
MOD_PKA_1	64	70	PF00069	0.547
MOD_PKA_2	131	137	PF00069	0.573
MOD_PKA_2	138	144	PF00069	0.611
MOD_PKA_2	64	70	PF00069	0.547
MOD_PKA_2	8	14	PF00069	0.555
MOD_Plk_2-3	50	56	PF00069	0.519
MOD_Plk_4	117	123	PF00069	0.577
MOD_Plk_4	165	171	PF00069	0.521
MOD_ProDKin_1	45	51	PF00069	0.604
TRG_DiLeu_BaEn_1	165	170	PF01217	0.521
TRG_ENDOCYTIC_2	167	170	PF00928	0.520
TRG_ENDOCYTIC_2	59	62	PF00928	0.569
TRG_ER_diArg_1	130	133	PF00400	0.493
TRG_NLS_MonoExtC_3	4	9	PF00514	0.672
TRG_NLS_MonoExtN_4	5	10	PF00514	0.671

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X2A2	Leishmania donovani	88%	100%
A4HHA5	Leishmania braziliensis	74%	100%
A4I4F1	Leishmania infantum	87%	100%
E9ADV1	Leishmania major	90%	100%