Putative kinesin

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative kinesin

Gene product:

kinesin, putative

Species:

Leishmania mexicana

UniProt:

E9ALX5_LEIMU

TriTrypDb:

LmxM.08_29.0970

Length:

1730

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005871	kinesin complex	3	1
GO:0005874	microtubule	6	1
GO:0005875	microtubule associated complex	2	1
GO:0032991	protein-containing complex	1	1
GO:0099080	supramolecular complex	2	1
GO:0099081	supramolecular polymer	3	1
GO:0099512	supramolecular fiber	4	1
GO:0099513	polymeric cytoskeletal fiber	5	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

E9ALX5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0007017	microtubule-based process	2	7
GO:0007018	microtubule-based movement	3	7
GO:0009987	cellular process	1	7

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003774	cytoskeletal motor activity	1	7
GO:0003777	microtubule motor activity	2	7
GO:0003824	catalytic activity	1	4
GO:0005488	binding	1	7
GO:0005515	protein binding	2	7
GO:0005524	ATP binding	5	7
GO:0008017	microtubule binding	5	7
GO:0008092	cytoskeletal protein binding	3	7
GO:0015631	tubulin binding	4	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1674	1678	PF00656	0.495
CLV_C14_Caspase3-7	327	331	PF00656	0.288
CLV_NRD_NRD_1	1070	1072	PF00675	0.472
CLV_NRD_NRD_1	1161	1163	PF00675	0.425
CLV_NRD_NRD_1	1265	1267	PF00675	0.391
CLV_NRD_NRD_1	1283	1285	PF00675	0.601
CLV_NRD_NRD_1	1322	1324	PF00675	0.487
CLV_NRD_NRD_1	1371	1373	PF00675	0.536
CLV_NRD_NRD_1	1382	1384	PF00675	0.446
CLV_NRD_NRD_1	1476	1478	PF00675	0.522

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8R3	Leptomonas seymouri	64%	99%
A0A3S7X299	Leishmania donovani	92%	100%
A4HHA9	Leishmania braziliensis	82%	100%
A4I4F5	Leishmania infantum	92%	100%
E9ADV5	Leishmania major	92%	100%

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