LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Putative lipase domain protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative lipase domain protein
Gene product:
lipase domain protein, putative
Species:
Leishmania mexicana
UniProt:
E9ALU5_LEIMU
TriTrypDb:
LmxM.08_29.1280
Length:
1877

Annotations

LeishMANIAdb annotations

A complex protein containing a putative transporter domain and a C-terminal lipase domain. The gene family already expanded in free-living kinetoplastids.

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 1
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6
Previous1Next

Expansion

Sequence features

E9ALU5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0006629 lipid metabolic process 3 6
GO:0008152 metabolic process 1 6
GO:0044238 primary metabolic process 2 6
GO:0071704 organic substance metabolic process 2 6
Previous1Next
Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 4
GO:0004806 triglyceride lipase activity 5 4
GO:0016298 lipase activity 4 4
GO:0016787 hydrolase activity 2 4
GO:0016788 hydrolase activity, acting on ester bonds 3 4
GO:0052689 carboxylic ester hydrolase activity 4 4
Previous1Next

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1102 1106 PF00656 0.660
CLV_C14_Caspase3-7 1300 1304 PF00656 0.664
CLV_C14_Caspase3-7 1394 1398 PF00656 0.532
CLV_C14_Caspase3-7 1448 1452 PF00656 0.616
CLV_C14_Caspase3-7 191 195 PF00656 0.579
CLV_C14_Caspase3-7 617 621 PF00656 0.385
CLV_C14_Caspase3-7 7 11 PF00656 0.612
CLV_NRD_NRD_1 1003 1005 PF00675 0.406
CLV_NRD_NRD_1 105 107 PF00675 0.512
CLV_NRD_NRD_1 1050 1052 PF00675 0.293
Previous12345…60Next

Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IEA4 Leishmania donovani 81% 99%
A4HHD9 Leishmania braziliensis 61% 98%
A4I4I5 Leishmania infantum 82% 99%
E9ADY6 Leishmania major 81% 100%
Previous1Next

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS