Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ALR9_LEIMU

TriTrypDb:

LmxM.08_29.1550

Length:

667

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

E9ALR9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALR9

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	512	516	PF00656	0.654
CLV_C14_Caspase3-7	524	528	PF00656	0.728
CLV_NRD_NRD_1	142	144	PF00675	0.706
CLV_NRD_NRD_1	208	210	PF00675	0.442
CLV_NRD_NRD_1	214	216	PF00675	0.443
CLV_NRD_NRD_1	368	370	PF00675	0.504
CLV_NRD_NRD_1	552	554	PF00675	0.637
CLV_NRD_NRD_1	563	565	PF00675	0.534
CLV_NRD_NRD_1	58	60	PF00675	0.462
CLV_PCSK_KEX2_1	142	144	PF00082	0.727

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMM3	Leptomonas seymouri	48%	84%
A0A3Q8IHB4	Leishmania donovani	86%	85%
A4I4L6	Leishmania infantum	86%	78%
E9AE14	Leishmania major	87%	100%

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