Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9ALN2_LEIMU

TriTrypDb:

LmxM.08_29.1920

Length:

275

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ALN2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALN2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	222	226	PF00656	0.682
CLV_NRD_NRD_1	158	160	PF00675	0.706
CLV_NRD_NRD_1	163	165	PF00675	0.592
CLV_NRD_NRD_1	248	250	PF00675	0.604
CLV_PCSK_FUR_1	246	250	PF00082	0.718
CLV_PCSK_KEX2_1	158	160	PF00082	0.658
CLV_PCSK_KEX2_1	163	165	PF00082	0.643
CLV_PCSK_KEX2_1	246	248	PF00082	0.629
CLV_PCSK_KEX2_1	270	272	PF00082	0.609
CLV_PCSK_PC1ET2_1	270	272	PF00082	0.666
CLV_PCSK_PC7_1	159	165	PF00082	0.588
CLV_PCSK_PC7_1	242	248	PF00082	0.500
CLV_PCSK_SKI1_1	175	179	PF00082	0.674
CLV_PCSK_SKI1_1	249	253	PF00082	0.605
DEG_SPOP_SBC_1	99	103	PF00917	0.707
DOC_CKS1_1	69	74	PF01111	0.650
DOC_CYCLIN_yCln2_LP_2	252	255	PF00134	0.731
DOC_MAPK_DCC_7	8	18	PF00069	0.585
DOC_MAPK_gen_1	129	138	PF00069	0.600
DOC_MAPK_gen_1	172	181	PF00069	0.699
DOC_MAPK_gen_1	246	253	PF00069	0.612
DOC_MAPK_MEF2A_6	172	181	PF00069	0.697
DOC_MAPK_MEF2A_6	260	269	PF00069	0.698
DOC_PP1_RVXF_1	173	179	PF00149	0.608
DOC_PP2B_LxvP_1	252	255	PF13499	0.731
DOC_PP4_FxxP_1	113	116	PF00568	0.644
DOC_USP7_MATH_1	120	124	PF00917	0.644
DOC_USP7_MATH_1	188	192	PF00917	0.663
DOC_USP7_MATH_1	211	215	PF00917	0.677
DOC_USP7_MATH_1	219	223	PF00917	0.666
DOC_USP7_MATH_1	7	11	PF00917	0.555
DOC_USP7_MATH_1	99	103	PF00917	0.702
DOC_USP7_UBL2_3	224	228	PF12436	0.726
DOC_WW_Pin1_4	102	107	PF00397	0.802
DOC_WW_Pin1_4	182	187	PF00397	0.600
DOC_WW_Pin1_4	68	73	PF00397	0.650
LIG_14-3-3_CanoR_1	121	125	PF00244	0.675
LIG_14-3-3_CanoR_1	158	166	PF00244	0.682
LIG_14-3-3_CanoR_1	189	193	PF00244	0.664
LIG_14-3-3_CanoR_1	209	218	PF00244	0.429
LIG_Actin_WH2_2	177	195	PF00022	0.691
LIG_BIR_II_1	1	5	PF00653	0.726
LIG_FHA_1	195	201	PF00498	0.604
LIG_FHA_1	259	265	PF00498	0.558
LIG_FHA_1	52	58	PF00498	0.678
LIG_FHA_1	78	84	PF00498	0.657
LIG_LIR_Apic_2	111	116	PF02991	0.594
LIG_LIR_Apic_2	123	127	PF02991	0.704
LIG_LIR_Gen_1	261	269	PF02991	0.601
LIG_LIR_Nem_3	261	265	PF02991	0.574
LIG_SH2_CRK	124	128	PF00017	0.706
LIG_SH2_STAP1	118	122	PF00017	0.642
LIG_SH2_STAT5	207	210	PF00017	0.704
LIG_SH3_3	136	142	PF00018	0.612
LIG_SH3_3	25	31	PF00018	0.742
MOD_CDK_SPxxK_3	182	189	PF00069	0.604
MOD_CK1_1	201	207	PF00069	0.689
MOD_CK1_1	212	218	PF00069	0.664
MOD_CK1_1	220	226	PF00069	0.563
MOD_CK1_1	98	104	PF00069	0.818
MOD_CK2_1	193	199	PF00069	0.706
MOD_GlcNHglycan	106	109	PF01048	0.598
MOD_GlcNHglycan	167	171	PF01048	0.795
MOD_GlcNHglycan	211	214	PF01048	0.656
MOD_GlcNHglycan	219	222	PF01048	0.655
MOD_GlcNHglycan	96	100	PF01048	0.786
MOD_GSK3_1	104	111	PF00069	0.592
MOD_GSK3_1	166	173	PF00069	0.500
MOD_GSK3_1	188	195	PF00069	0.691
MOD_GSK3_1	209	216	PF00069	0.658
MOD_GSK3_1	47	54	PF00069	0.681
MOD_GSK3_1	94	101	PF00069	0.775
MOD_NEK2_1	1	6	PF00069	0.703
MOD_NEK2_1	192	197	PF00069	0.613
MOD_NEK2_2	108	113	PF00069	0.499
MOD_NEK2_2	188	193	PF00069	0.690
MOD_PIKK_1	240	246	PF00454	0.775
MOD_PKA_1	158	164	PF00069	0.727
MOD_PKA_2	120	126	PF00069	0.693
MOD_PKA_2	158	164	PF00069	0.811
MOD_PKA_2	188	194	PF00069	0.666
MOD_PKA_2	87	93	PF00069	0.520
MOD_Plk_1	198	204	PF00069	0.610
MOD_Plk_1	47	53	PF00069	0.790
MOD_Plk_4	108	114	PF00069	0.499
MOD_ProDKin_1	102	108	PF00069	0.797
MOD_ProDKin_1	182	188	PF00069	0.602
MOD_ProDKin_1	68	74	PF00069	0.649
TRG_ER_diArg_1	246	249	PF00400	0.630

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZ42	Leptomonas seymouri	37%	100%
A0A3Q8IBJ9	Leishmania donovani	87%	100%
A4HHJ2	Leishmania braziliensis	69%	100%
A4I4Q0	Leishmania infantum	88%	100%
E9AE53	Leishmania major	87%	100%