Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ALN0_LEIMU

TriTrypDb:

LmxM.08_29.1940

Length:

278

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ALN0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALN0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	158	162	PF00656	0.518
CLV_NRD_NRD_1	228	230	PF00675	0.455
CLV_NRD_NRD_1	82	84	PF00675	0.511
CLV_PCSK_KEX2_1	228	230	PF00082	0.455
CLV_PCSK_KEX2_1	82	84	PF00082	0.511
CLV_PCSK_SKI1_1	148	152	PF00082	0.556
CLV_PCSK_SKI1_1	206	210	PF00082	0.618
CLV_PCSK_SKI1_1	271	275	PF00082	0.604
DEG_Nend_UBRbox_4	1	3	PF02207	0.430
DOC_PP1_RVXF_1	269	276	PF00149	0.493
DOC_PP2B_LxvP_1	170	173	PF13499	0.541
DOC_PP2B_LxvP_1	30	33	PF13499	0.458
DOC_USP7_MATH_1	153	157	PF00917	0.605
DOC_USP7_MATH_1	33	37	PF00917	0.440
DOC_USP7_MATH_1	93	97	PF00917	0.507
DOC_USP7_UBL2_3	263	267	PF12436	0.460
DOC_WW_Pin1_4	104	109	PF00397	0.629
DOC_WW_Pin1_4	114	119	PF00397	0.763
DOC_WW_Pin1_4	138	143	PF00397	0.511
DOC_WW_Pin1_4	174	179	PF00397	0.491
DOC_WW_Pin1_4	31	36	PF00397	0.589
LIG_14-3-3_CanoR_1	103	108	PF00244	0.743
LIG_14-3-3_CanoR_1	15	24	PF00244	0.443
LIG_BRCT_BRCA1_1	33	37	PF00533	0.454
LIG_CtBP_PxDLS_1	27	31	PF00389	0.450
LIG_deltaCOP1_diTrp_1	230	238	PF00928	0.470
LIG_EVH1_1	23	27	PF00568	0.450
LIG_FHA_1	197	203	PF00498	0.472
LIG_FHA_2	149	155	PF00498	0.752
LIG_FHA_2	164	170	PF00498	0.472
LIG_LIR_Apic_2	104	108	PF02991	0.585
LIG_LIR_Gen_1	230	241	PF02991	0.427
LIG_LIR_Gen_1	34	44	PF02991	0.442
LIG_LIR_Nem_3	107	113	PF02991	0.748
LIG_LIR_Nem_3	18	23	PF02991	0.446
LIG_LIR_Nem_3	182	187	PF02991	0.452
LIG_LIR_Nem_3	230	236	PF02991	0.432
LIG_LIR_Nem_3	34	40	PF02991	0.448
LIG_MYND_1	123	127	PF01753	0.647
LIG_PDZ_Class_2	273	278	PF00595	0.570
LIG_SH2_CRK	105	109	PF00017	0.641
LIG_SH2_GRB2like	113	116	PF00017	0.664
LIG_SH2_GRB2like	181	184	PF00017	0.516
LIG_SH2_GRB2like	187	190	PF00017	0.406
LIG_SH2_NCK_1	105	109	PF00017	0.641
LIG_SH2_SRC	187	190	PF00017	0.447
LIG_SH2_STAP1	191	195	PF00017	0.434
LIG_SH2_STAT5	110	113	PF00017	0.659
LIG_SH2_STAT5	187	190	PF00017	0.447
LIG_SH2_STAT5	194	197	PF00017	0.415
LIG_SH2_STAT5	20	23	PF00017	0.449
LIG_SH2_STAT5	231	234	PF00017	0.435
LIG_SH3_1	60	66	PF00018	0.473
LIG_SH3_3	117	123	PF00018	0.657
LIG_SH3_3	170	176	PF00018	0.504
LIG_SH3_3	21	27	PF00018	0.555
LIG_SH3_3	60	66	PF00018	0.604
LIG_SH3_3	87	93	PF00018	0.661
LIG_SUMO_SIM_par_1	26	31	PF11976	0.449
LIG_WRC_WIRS_1	232	237	PF05994	0.427
MOD_CDK_SPxxK_3	114	121	PF00069	0.494
MOD_CK1_1	104	110	PF00069	0.612
MOD_CK1_1	138	144	PF00069	0.671
MOD_CK1_1	156	162	PF00069	0.530
MOD_CK1_1	31	37	PF00069	0.574
MOD_CK1_1	46	52	PF00069	0.421
MOD_GlcNHglycan	128	131	PF01048	0.560
MOD_GlcNHglycan	154	158	PF01048	0.678
MOD_GlcNHglycan	203	206	PF01048	0.419
MOD_GlcNHglycan	45	48	PF01048	0.479
MOD_GlcNHglycan	57	60	PF01048	0.439
MOD_GlcNHglycan	87	90	PF01048	0.490
MOD_GSK3_1	104	111	PF00069	0.652
MOD_GSK3_1	11	18	PF00069	0.435
MOD_GSK3_1	126	133	PF00069	0.634
MOD_GSK3_1	144	151	PF00069	0.826
MOD_N-GLC_1	114	119	PF02516	0.498
MOD_NEK2_1	195	200	PF00069	0.613
MOD_NEK2_1	201	206	PF00069	0.434
MOD_NEK2_1	28	33	PF00069	0.514
MOD_NEK2_1	55	60	PF00069	0.455
MOD_NEK2_2	108	113	PF00069	0.563
MOD_NEK2_2	93	98	PF00069	0.560
MOD_PIKK_1	196	202	PF00454	0.561
MOD_PIKK_1	246	252	PF00454	0.501
MOD_PKA_2	255	261	PF00069	0.541
MOD_PKB_1	13	21	PF00069	0.437
MOD_Plk_1	196	202	PF00069	0.470
MOD_Plk_2-3	163	169	PF00069	0.623
MOD_Plk_4	108	114	PF00069	0.671
MOD_ProDKin_1	104	110	PF00069	0.633
MOD_ProDKin_1	114	120	PF00069	0.757
MOD_ProDKin_1	138	144	PF00069	0.513
MOD_ProDKin_1	174	180	PF00069	0.491
MOD_ProDKin_1	31	37	PF00069	0.589
TRG_ER_diArg_1	13	16	PF00400	0.431
TRG_ER_diArg_1	227	229	PF00400	0.444
TRG_ER_diArg_1	81	83	PF00400	0.510
TRG_Pf-PMV_PEXEL_1	69	74	PF00026	0.464

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTK9	Leptomonas seymouri	37%	100%
A0A3Q8IF97	Leishmania donovani	88%	91%
A4I4Q2	Leishmania infantum	91%	100%
E9AE55	Leishmania major	89%	100%