LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Flavoprotein oxygenase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Flavoprotein oxygenase
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9ALM4_LEIMU
TriTrypDb:
LmxM.08_29.1995
Length:
367

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0005815 microtubule organizing center 2 1
GO:0036064 ciliary basal body 3 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9ALM4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALM4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 126 128 PF00675 0.605
CLV_NRD_NRD_1 132 134 PF00675 0.645
CLV_NRD_NRD_1 15 17 PF00675 0.816
CLV_PCSK_KEX2_1 126 128 PF00082 0.688
CLV_PCSK_KEX2_1 131 133 PF00082 0.768
CLV_PCSK_KEX2_1 15 17 PF00082 0.816
CLV_PCSK_KEX2_1 217 219 PF00082 0.716
CLV_PCSK_KEX2_1 326 328 PF00082 0.482
CLV_PCSK_KEX2_1 82 84 PF00082 0.838
CLV_PCSK_PC1ET2_1 217 219 PF00082 0.716
CLV_PCSK_PC1ET2_1 326 328 PF00082 0.482
CLV_PCSK_PC1ET2_1 82 84 PF00082 0.838
CLV_PCSK_PC7_1 122 128 PF00082 0.653
CLV_PCSK_PC7_1 322 328 PF00082 0.477
CLV_PCSK_SKI1_1 122 126 PF00082 0.617
CLV_PCSK_SKI1_1 15 19 PF00082 0.713
CLV_PCSK_SKI1_1 227 231 PF00082 0.684
DEG_APCC_DBOX_1 121 129 PF00400 0.447
DOC_CKS1_1 264 269 PF01111 0.368
DOC_CYCLIN_RxL_1 117 129 PF00134 0.446
DOC_CYCLIN_RxL_1 13 24 PF00134 0.461
DOC_MAPK_gen_1 326 334 PF00069 0.256
DOC_MAPK_MEF2A_6 326 334 PF00069 0.443
DOC_PP1_SILK_1 227 232 PF00149 0.471
DOC_PP4_FxxP_1 103 106 PF00568 0.469
DOC_PP4_FxxP_1 306 309 PF00568 0.382
DOC_USP7_MATH_1 171 175 PF00917 0.550
DOC_USP7_MATH_1 242 246 PF00917 0.403
DOC_USP7_MATH_1 25 29 PF00917 0.552
DOC_USP7_MATH_1 270 274 PF00917 0.597
DOC_USP7_MATH_1 59 63 PF00917 0.591
DOC_USP7_MATH_1 94 98 PF00917 0.392
DOC_WW_Pin1_4 185 190 PF00397 0.462
DOC_WW_Pin1_4 21 26 PF00397 0.604
DOC_WW_Pin1_4 263 268 PF00397 0.526
DOC_WW_Pin1_4 325 330 PF00397 0.391
DOC_WW_Pin1_4 335 340 PF00397 0.307
LIG_14-3-3_CanoR_1 126 135 PF00244 0.474
LIG_14-3-3_CanoR_1 198 207 PF00244 0.353
LIG_14-3-3_CanoR_1 76 81 PF00244 0.434
LIG_Actin_WH2_2 212 229 PF00022 0.440
LIG_BIR_III_2 294 298 PF00653 0.503
LIG_BRCT_BRCA1_1 34 38 PF00533 0.531
LIG_BRCT_BRCA1_1 49 53 PF00533 0.403
LIG_FHA_1 340 346 PF00498 0.407
LIG_FHA_1 86 92 PF00498 0.447
LIG_FHA_2 165 171 PF00498 0.568
LIG_FHA_2 59 65 PF00498 0.562
LIG_Integrin_RGD_1 73 75 PF01839 0.634
LIG_LIR_Gen_1 266 272 PF02991 0.529
LIG_LIR_Gen_1 310 319 PF02991 0.315
LIG_LIR_Nem_3 205 211 PF02991 0.404
LIG_LIR_Nem_3 266 271 PF02991 0.527
LIG_LIR_Nem_3 310 315 PF02991 0.376
LIG_NRBOX 120 126 PF00104 0.423
LIG_SH2_NCK_1 249 253 PF00017 0.435
LIG_SH2_SRC 249 252 PF00017 0.437
LIG_SH2_STAP1 249 253 PF00017 0.435
LIG_SH3_1 261 267 PF00018 0.335
LIG_SH3_3 186 192 PF00018 0.390
LIG_SH3_3 261 267 PF00018 0.335
LIG_TRAF2_1 138 141 PF00917 0.398
LIG_TRAF2_1 153 156 PF00917 0.485
MOD_CDK_SPxK_1 325 331 PF00069 0.508
MOD_CK1_1 174 180 PF00069 0.405
MOD_CK1_1 21 27 PF00069 0.645
MOD_CK1_1 287 293 PF00069 0.627
MOD_CK1_1 30 36 PF00069 0.659
MOD_CK1_1 51 57 PF00069 0.511
MOD_CK2_1 150 156 PF00069 0.592
MOD_CK2_1 164 170 PF00069 0.730
MOD_CK2_1 58 64 PF00069 0.711
MOD_Cter_Amidation 273 276 PF01082 0.552
MOD_GlcNHglycan 110 113 PF01048 0.486
MOD_GlcNHglycan 155 160 PF01048 0.708
MOD_GlcNHglycan 20 23 PF01048 0.610
MOD_GlcNHglycan 200 203 PF01048 0.609
MOD_GlcNHglycan 244 247 PF01048 0.474
MOD_GlcNHglycan 272 275 PF01048 0.680
MOD_GlcNHglycan 281 284 PF01048 0.539
MOD_GlcNHglycan 29 32 PF01048 0.579
MOD_GlcNHglycan 34 37 PF01048 0.565
MOD_GlcNHglycan 50 53 PF01048 0.497
MOD_GSK3_1 162 169 PF00069 0.762
MOD_GSK3_1 21 28 PF00069 0.679
MOD_GSK3_1 270 277 PF00069 0.668
MOD_GSK3_1 32 39 PF00069 0.758
MOD_GSK3_1 335 342 PF00069 0.407
MOD_GSK3_1 47 54 PF00069 0.654
MOD_N-GLC_1 26 31 PF02516 0.616
MOD_N-GLC_1 69 74 PF02516 0.552
MOD_NEK2_1 18 23 PF00069 0.620
MOD_NEK2_1 180 185 PF00069 0.516
MOD_NEK2_1 26 31 PF00069 0.606
MOD_NEK2_1 32 37 PF00069 0.622
MOD_NEK2_2 171 176 PF00069 0.557
MOD_NEK2_2 222 227 PF00069 0.505
MOD_NEK2_2 339 344 PF00069 0.504
MOD_PIKK_1 157 163 PF00454 0.700
MOD_PK_1 76 82 PF00069 0.535
MOD_PKA_1 126 132 PF00069 0.615
MOD_PKA_2 126 132 PF00069 0.634
MOD_PKA_2 36 42 PF00069 0.754
MOD_PKB_1 131 139 PF00069 0.486
MOD_ProDKin_1 185 191 PF00069 0.593
MOD_ProDKin_1 21 27 PF00069 0.773
MOD_ProDKin_1 263 269 PF00069 0.672
MOD_ProDKin_1 325 331 PF00069 0.475
MOD_ProDKin_1 335 341 PF00069 0.307
TRG_ENDOCYTIC_2 249 252 PF00928 0.427
TRG_ENDOCYTIC_2 268 271 PF00928 0.656
TRG_ER_diArg_1 125 127 PF00400 0.530
TRG_ER_diArg_1 131 133 PF00400 0.616
TRG_ER_diArg_1 15 17 PF00400 0.774
TRG_ER_diArg_1 320 323 PF00400 0.508

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PBV2 Leptomonas seymouri 42% 91%
A0A3Q8IIX3 Leishmania donovani 85% 99%
E9AE61 Leishmania major 82% 100%
E9AIT7 Leishmania braziliensis 69% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS