Putative heat shock protein 20

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

heat shock protein 20, putative

Species:

Leishmania mexicana

UniProt:

E9ALH9_LEIMU

TriTrypDb:

LmxM.08_29.2450

Length:

155

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9ALH9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALH9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	88	90	PF00675	0.229
CLV_PCSK_KEX2_1	7	9	PF00082	0.510
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.483
CLV_PCSK_SKI1_1	31	35	PF00082	0.476
CLV_PCSK_SKI1_1	90	94	PF00082	0.298
DEG_Nend_Nbox_1	1	3	PF02207	0.525
DEG_SCF_FBW7_1	116	122	PF00400	0.135
DOC_CKS1_1	116	121	PF01111	0.197
DOC_MAPK_DCC_7	43	52	PF00069	0.529
DOC_MAPK_gen_1	69	75	PF00069	0.398
DOC_MAPK_MEF2A_6	43	52	PF00069	0.529
DOC_PP4_FxxP_1	114	117	PF00568	0.368
DOC_USP7_MATH_1	119	123	PF00917	0.173
DOC_USP7_MATH_1	39	43	PF00917	0.438
DOC_USP7_UBL2_3	90	94	PF12436	0.375
DOC_WW_Pin1_4	115	120	PF00397	0.200
DOC_WW_Pin1_4	145	150	PF00397	0.148
LIG_14-3-3_CanoR_1	74	83	PF00244	0.349
LIG_APCC_ABBA_1	73	78	PF00400	0.368
LIG_BRCT_BRCA1_1	34	38	PF00533	0.579
LIG_CSL_BTD_1	1	4	PF09270	0.525
LIG_FHA_2	116	122	PF00498	0.263
LIG_FHA_2	126	132	PF00498	0.125
LIG_LIR_Apic_2	111	117	PF02991	0.368
LIG_LIR_Gen_1	56	66	PF02991	0.371
LIG_LIR_Nem_3	16	22	PF02991	0.489
LIG_LIR_Nem_3	56	62	PF02991	0.222
LIG_MLH1_MIPbox_1	34	38	PF16413	0.579
LIG_MYND_1	26	30	PF01753	0.438
LIG_Pex14_2	110	114	PF04695	0.368
LIG_Pex14_2	21	25	PF04695	0.490
LIG_Pex14_2	34	38	PF04695	0.389
LIG_REV1ctd_RIR_1	35	45	PF16727	0.583
LIG_SH2_CRK	59	63	PF00017	0.197
LIG_SH2_NCK_1	59	63	PF00017	0.341
LIG_SH2_STAP1	59	63	PF00017	0.399
LIG_SH2_STAT5	59	62	PF00017	0.368
LIG_SH2_STAT5	76	79	PF00017	0.263
LIG_SH3_3	133	139	PF00018	0.341
LIG_UBA3_1	82	90	PF00899	0.378
LIG_WRC_WIRS_1	34	39	PF05994	0.550
MOD_CK1_1	42	48	PF00069	0.504
MOD_DYRK1A_RPxSP_1	145	149	PF00069	0.135
MOD_GlcNHglycan	145	148	PF01048	0.293
MOD_GlcNHglycan	85	88	PF01048	0.269
MOD_GSK3_1	115	122	PF00069	0.326
MOD_GSK3_1	141	148	PF00069	0.237
MOD_GSK3_1	33	40	PF00069	0.511
MOD_GSK3_1	7	14	PF00069	0.505
MOD_GSK3_1	74	81	PF00069	0.368
MOD_N-GLC_1	134	139	PF02516	0.399
MOD_NEK2_1	134	139	PF00069	0.261
MOD_NEK2_1	141	146	PF00069	0.281
MOD_NEK2_1	33	38	PF00069	0.490
MOD_PKA_1	7	13	PF00069	0.477
MOD_PKA_2	104	110	PF00069	0.192
MOD_PKA_2	141	147	PF00069	0.316
MOD_PKA_2	42	48	PF00069	0.461
MOD_PKA_2	7	13	PF00069	0.477
MOD_Plk_1	134	140	PF00069	0.384
MOD_Plk_1	77	83	PF00069	0.257
MOD_Plk_4	33	39	PF00069	0.486
MOD_Plk_4	42	48	PF00069	0.418
MOD_Plk_4	57	63	PF00069	0.201
MOD_Plk_4	7	13	PF00069	0.477
MOD_Plk_4	78	84	PF00069	0.349
MOD_ProDKin_1	115	121	PF00069	0.200
MOD_ProDKin_1	145	151	PF00069	0.148
MOD_SUMO_for_1	68	71	PF00179	0.212
TRG_DiLeu_BaEn_1	97	102	PF01217	0.263
TRG_ENDOCYTIC_2	59	62	PF00928	0.221

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHY2	Leptomonas seymouri	61%	100%
A0A0S4ITJ1	Bodo saltans	39%	100%
A0A1X0P9Y3	Trypanosomatidae	39%	100%
A0A3Q8IBN6	Leishmania donovani	94%	100%
A0A3R7N2L9	Trypanosoma rangeli	43%	100%
A4HHP4	Leishmania braziliensis	81%	100%
A4I4V9	Leishmania infantum	94%	100%
C9ZL02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	100%
E9AEA7	Leishmania major	90%	100%
O14368	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	100%
O74984	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	100%
O82013	Solanum peruvianum	28%	100%
P04794	Glycine max	31%	100%
P05478	Glycine max	32%	96%
P15992	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	72%
P19244	Pisum sativum	30%	79%
P27880	Medicago sativa	36%	98%
P29830	Arabidopsis thaliana	29%	100%
P30236	Glycine max	30%	81%
P46516	Helianthus annuus	27%	97%
Q01545	Ipomoea nil	30%	93%
Q06823	Stigmatella aurantiaca (strain DW4/3-1)	30%	92%
Q38806	Arabidopsis thaliana	30%	79%
Q4UKR8	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)	28%	100%
Q53M11	Oryza sativa subsp. japonica	31%	75%
Q7XUW5	Oryza sativa subsp. japonica	34%	72%
Q943Q3	Oryza sativa subsp. japonica	29%	100%
Q9XIE3	Arabidopsis thaliana	36%	100%
Q9ZW31	Arabidopsis thaliana	34%	100%
V5BXI2	Trypanosoma cruzi	44%	100%