Putative helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative helicase

Gene product:

helicase, putative

Species:

Leishmania mexicana

UniProt:

E9ALF8_LEIMU

TriTrypDb:

LmxM.08_29.2660

Length:

953

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	11
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11

Expansion

Sequence features

E9ALF8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALF8

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0000018	regulation of DNA recombination	6	1
GO:0000723	telomere maintenance	5	1
GO:0006259	DNA metabolic process	4	1
GO:0006282	regulation of DNA repair	6	1
GO:0006996	organelle organization	4	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0010569	regulation of double-strand break repair via homologous recombination	7	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0016043	cellular component organization	3	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0032200	telomere organization	6	1
GO:0032204	regulation of telomere maintenance	6	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0033043	regulation of organelle organization	5	1
GO:0033044	regulation of chromosome organization	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044087	regulation of cellular component biogenesis	4	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0045910	negative regulation of DNA recombination	7	1
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0048583	regulation of response to stimulus	3	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051052	regulation of DNA metabolic process	5	1
GO:0051053	negative regulation of DNA metabolic process	6	1
GO:0051128	regulation of cellular component organization	4	1
GO:0051129	negative regulation of cellular component organization	5	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0051276	chromosome organization	5	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071103	DNA conformation change	6	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0080134	regulation of response to stress	4	1
GO:0080135	regulation of cellular response to stress	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:0090657	telomeric loop disassembly	6	1
GO:1904429	regulation of t-circle formation	5	1
GO:1904430	negative regulation of t-circle formation	6	1
GO:2000779	regulation of double-strand break repair	7	1
GO:2001020	obsolete regulation of response to DNA damage stimulus	5	1
GO:0006950	response to stress	2	3
GO:0006974	DNA damage response	4	3
GO:0033554	cellular response to stress	3	3
GO:0050896	response to stimulus	1	3
GO:0051716	cellular response to stimulus	2	3

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0005515	protein binding	2	1
GO:0019899	enzyme binding	3	1
GO:0070182	DNA polymerase binding	4	1
GO:0016462	pyrophosphatase activity	5	1
GO:0016887	ATP hydrolysis activity	7	1
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	603	607	PF00656	0.467
CLV_C14_Caspase3-7	919	923	PF00656	0.339
CLV_MEL_PAP_1	498	504	PF00089	0.373
CLV_NRD_NRD_1	700	702	PF00675	0.366
CLV_NRD_NRD_1	722	724	PF00675	0.436
CLV_NRD_NRD_1	775	777	PF00675	0.506
CLV_PCSK_FUR_1	628	632	PF00082	0.201
CLV_PCSK_FUR_1	773	777	PF00082	0.604
CLV_PCSK_KEX2_1	106	108	PF00082	0.211
CLV_PCSK_KEX2_1	630	632	PF00082	0.201
CLV_PCSK_KEX2_1	699	701	PF00082	0.377
CLV_PCSK_KEX2_1	722	724	PF00082	0.412
CLV_PCSK_KEX2_1	773	775	PF00082	0.520
CLV_PCSK_PC1ET2_1	106	108	PF00082	0.196
CLV_PCSK_PC1ET2_1	630	632	PF00082	0.201
CLV_PCSK_SKI1_1	103	107	PF00082	0.187
CLV_PCSK_SKI1_1	129	133	PF00082	0.239
CLV_PCSK_SKI1_1	295	299	PF00082	0.292
CLV_PCSK_SKI1_1	342	346	PF00082	0.358
CLV_PCSK_SKI1_1	364	368	PF00082	0.395
CLV_PCSK_SKI1_1	374	378	PF00082	0.390
CLV_PCSK_SKI1_1	401	405	PF00082	0.298
CLV_PCSK_SKI1_1	557	561	PF00082	0.201
CLV_PCSK_SKI1_1	610	614	PF00082	0.322
CLV_PCSK_SKI1_1	647	651	PF00082	0.201
CLV_PCSK_SKI1_1	703	707	PF00082	0.222
CLV_PCSK_SKI1_1	781	785	PF00082	0.599
CLV_PCSK_SKI1_1	881	885	PF00082	0.375
CLV_PCSK_SKI1_1	891	895	PF00082	0.403
CLV_PCSK_SKI1_1	913	917	PF00082	0.430
DEG_SPOP_SBC_1	242	246	PF00917	0.439
DEG_SPOP_SBC_1	805	809	PF00917	0.463
DOC_ANK_TNKS_1	640	647	PF00023	0.334
DOC_CYCLIN_RxL_1	217	225	PF00134	0.411
DOC_CYCLIN_RxL_1	412	423	PF00134	0.434
DOC_CYCLIN_RxL_1	46	57	PF00134	0.294
DOC_CYCLIN_RxL_1	888	897	PF00134	0.373
DOC_CYCLIN_yCln2_LP_2	168	171	PF00134	0.397
DOC_MAPK_gen_1	595	604	PF00069	0.413
DOC_MAPK_gen_1	672	681	PF00069	0.467
DOC_MAPK_MEF2A_6	586	593	PF00069	0.425
DOC_MAPK_MEF2A_6	869	876	PF00069	0.274
DOC_MAPK_NFAT4_5	586	594	PF00069	0.424
DOC_PP1_RVXF_1	413	420	PF00149	0.427
DOC_PP2B_LxvP_1	168	171	PF13499	0.397
DOC_PP2B_LxvP_1	908	911	PF13499	0.467
DOC_PP4_FxxP_1	560	563	PF00568	0.401
DOC_USP7_MATH_1	142	146	PF00917	0.419
DOC_USP7_MATH_1	164	168	PF00917	0.486
DOC_USP7_MATH_1	375	379	PF00917	0.472
DOC_USP7_MATH_1	434	438	PF00917	0.430
DOC_USP7_MATH_1	528	532	PF00917	0.446
DOC_USP7_MATH_1	62	66	PF00917	0.545
DOC_USP7_MATH_1	783	787	PF00917	0.572
DOC_USP7_MATH_1	791	795	PF00917	0.619
DOC_USP7_MATH_1	800	804	PF00917	0.669
DOC_USP7_MATH_1	805	809	PF00917	0.699
DOC_USP7_MATH_1	817	821	PF00917	0.585
DOC_USP7_MATH_1	911	915	PF00917	0.507
DOC_USP7_UBL2_3	79	83	PF12436	0.479
DOC_WW_Pin1_4	249	254	PF00397	0.461
DOC_WW_Pin1_4	315	320	PF00397	0.606
DOC_WW_Pin1_4	40	45	PF00397	0.298
DOC_WW_Pin1_4	430	435	PF00397	0.351
DOC_WW_Pin1_4	443	448	PF00397	0.282
DOC_WW_Pin1_4	512	517	PF00397	0.434
DOC_WW_Pin1_4	580	585	PF00397	0.532
DOC_WW_Pin1_4	794	799	PF00397	0.573
DOC_WW_Pin1_4	824	829	PF00397	0.569
DOC_WW_Pin1_4	894	899	PF00397	0.440
LIG_14-3-3_CanoR_1	107	111	PF00244	0.505
LIG_14-3-3_CanoR_1	133	143	PF00244	0.376
LIG_14-3-3_CanoR_1	271	279	PF00244	0.440
LIG_14-3-3_CanoR_1	374	380	PF00244	0.468
LIG_14-3-3_CanoR_1	495	499	PF00244	0.358
LIG_14-3-3_CanoR_1	595	604	PF00244	0.401
LIG_14-3-3_CanoR_1	703	712	PF00244	0.407
LIG_14-3-3_CanoR_1	723	733	PF00244	0.355
LIG_14-3-3_CanoR_1	81	90	PF00244	0.389
LIG_14-3-3_CanoR_1	822	830	PF00244	0.503
LIG_Actin_WH2_2	573	588	PF00022	0.439
LIG_Actin_WH2_2	880	897	PF00022	0.479
LIG_APCC_ABBA_1	303	308	PF00400	0.359
LIG_APCC_ABBAyCdc20_2	701	707	PF00400	0.323
LIG_BRCT_BRCA1_1	12	16	PF00533	0.310
LIG_BRCT_BRCA1_1	328	332	PF00533	0.419
LIG_BRCT_BRCA1_1	398	402	PF00533	0.415
LIG_BRCT_BRCA1_1	860	864	PF00533	0.370
LIG_EH1_1	175	183	PF00400	0.401
LIG_FHA_1	113	119	PF00498	0.423
LIG_FHA_1	255	261	PF00498	0.357
LIG_FHA_1	339	345	PF00498	0.341
LIG_FHA_1	398	404	PF00498	0.418
LIG_FHA_1	48	54	PF00498	0.294
LIG_FHA_1	544	550	PF00498	0.445
LIG_FHA_1	564	570	PF00498	0.321
LIG_FHA_1	580	586	PF00498	0.427
LIG_FHA_1	727	733	PF00498	0.645
LIG_FHA_1	825	831	PF00498	0.509
LIG_FHA_2	648	654	PF00498	0.401
LIG_FHA_2	741	747	PF00498	0.451
LIG_FHA_2	821	827	PF00498	0.696
LIG_FHA_2	858	864	PF00498	0.403
LIG_FHA_2	917	923	PF00498	0.388
LIG_LIR_Gen_1	329	340	PF02991	0.423
LIG_LIR_Gen_1	525	533	PF02991	0.401
LIG_LIR_Gen_1	623	634	PF02991	0.401
LIG_LIR_Gen_1	702	713	PF02991	0.376
LIG_LIR_Gen_1	861	872	PF02991	0.337
LIG_LIR_Gen_1	875	885	PF02991	0.311
LIG_LIR_Gen_1	926	936	PF02991	0.370
LIG_LIR_Nem_3	13	19	PF02991	0.320
LIG_LIR_Nem_3	188	193	PF02991	0.436
LIG_LIR_Nem_3	329	335	PF02991	0.416
LIG_LIR_Nem_3	416	422	PF02991	0.320
LIG_LIR_Nem_3	548	553	PF02991	0.408
LIG_LIR_Nem_3	623	629	PF02991	0.434
LIG_LIR_Nem_3	675	680	PF02991	0.401
LIG_LIR_Nem_3	684	690	PF02991	0.401
LIG_LIR_Nem_3	702	708	PF02991	0.330
LIG_LIR_Nem_3	861	867	PF02991	0.360
LIG_LIR_Nem_3	875	880	PF02991	0.281
LIG_LIR_Nem_3	926	931	PF02991	0.396
LIG_LIR_Nem_3	937	942	PF02991	0.302
LIG_NRBOX	293	299	PF00104	0.434
LIG_NRBOX	904	910	PF00104	0.331
LIG_PCNA_PIPBox_1	379	388	PF02747	0.341
LIG_PCNA_PIPBox_1	529	538	PF02747	0.439
LIG_PCNA_yPIPBox_3	661	671	PF02747	0.401
LIG_Pex14_2	190	194	PF04695	0.467
LIG_REV1ctd_RIR_1	153	161	PF16727	0.487
LIG_REV1ctd_RIR_1	716	727	PF16727	0.521
LIG_RPA_C_Fungi	88	100	PF08784	0.170
LIG_SH2_CRK	210	214	PF00017	0.247
LIG_SH2_CRK	677	681	PF00017	0.247
LIG_SH2_CRK	712	716	PF00017	0.293
LIG_SH2_GRB2like	619	622	PF00017	0.326
LIG_SH2_NCK_1	712	716	PF00017	0.293
LIG_SH2_NCK_1	757	761	PF00017	0.503
LIG_SH2_PTP2	734	737	PF00017	0.660
LIG_SH2_SRC	306	309	PF00017	0.385
LIG_SH2_SRC	619	622	PF00017	0.379
LIG_SH2_SRC	757	760	PF00017	0.505
LIG_SH2_STAP1	110	114	PF00017	0.326
LIG_SH2_STAP1	712	716	PF00017	0.293
LIG_SH2_STAP1	84	88	PF00017	0.224
LIG_SH2_STAP1	943	947	PF00017	0.426
LIG_SH2_STAT3	19	22	PF00017	0.320
LIG_SH2_STAT5	193	196	PF00017	0.292
LIG_SH2_STAT5	212	215	PF00017	0.136
LIG_SH2_STAT5	633	636	PF00017	0.253
LIG_SH2_STAT5	734	737	PF00017	0.660
LIG_SH2_STAT5	90	93	PF00017	0.233
LIG_SH3_3	203	209	PF00018	0.233
LIG_SH3_3	428	434	PF00018	0.458
LIG_SH3_3	465	471	PF00018	0.388
LIG_SH3_3	518	524	PF00018	0.233
LIG_SH3_3	636	642	PF00018	0.317
LIG_SH3_3	9	15	PF00018	0.301
LIG_SUMO_SIM_anti_2	204	209	PF11976	0.360
LIG_SUMO_SIM_anti_2	829	834	PF11976	0.493
LIG_SUMO_SIM_par_1	229	235	PF11976	0.237
LIG_SUMO_SIM_par_1	252	258	PF11976	0.342
LIG_SUMO_SIM_par_1	678	685	PF11976	0.326
LIG_TRAF2_1	284	287	PF00917	0.426
LIG_TRFH_1	212	216	PF08558	0.379
LIG_TYR_ITIM	732	737	PF00017	0.657
LIG_UBA3_1	331	337	PF00899	0.293
LIG_UBA3_1	552	557	PF00899	0.290
LIG_UBA3_1	625	630	PF00899	0.233
MOD_CDC14_SPxK_1	583	586	PF00782	0.379
MOD_CDK_SPxK_1	580	586	PF00069	0.417
MOD_CK1_1	241	247	PF00069	0.326
MOD_CK1_1	317	323	PF00069	0.410
MOD_CK1_1	493	499	PF00069	0.388
MOD_CK1_1	749	755	PF00069	0.514
MOD_CK1_1	794	800	PF00069	0.530
MOD_CK1_1	807	813	PF00069	0.594
MOD_CK1_1	820	826	PF00069	0.595
MOD_CK1_1	923	929	PF00069	0.324
MOD_CK2_1	690	696	PF00069	0.390
MOD_CK2_1	740	746	PF00069	0.713
MOD_CK2_1	820	826	PF00069	0.697
MOD_CK2_1	857	863	PF00069	0.379
MOD_Cter_Amidation	720	723	PF01082	0.331
MOD_GlcNHglycan	144	147	PF01048	0.357
MOD_GlcNHglycan	160	163	PF01048	0.299
MOD_GlcNHglycan	187	190	PF01048	0.379
MOD_GlcNHglycan	245	248	PF01048	0.333
MOD_GlcNHglycan	355	358	PF01048	0.521
MOD_GlcNHglycan	441	444	PF01048	0.293
MOD_GlcNHglycan	483	486	PF01048	0.364
MOD_GlcNHglycan	539	542	PF01048	0.305
MOD_GlcNHglycan	749	752	PF01048	0.459
MOD_GlcNHglycan	785	788	PF01048	0.569
MOD_GlcNHglycan	793	796	PF01048	0.498
MOD_GlcNHglycan	823	826	PF01048	0.596
MOD_GlcNHglycan	833	836	PF01048	0.528
MOD_GSK3_1	129	136	PF00069	0.349
MOD_GSK3_1	142	149	PF00069	0.235
MOD_GSK3_1	238	245	PF00069	0.261
MOD_GSK3_1	311	318	PF00069	0.574
MOD_GSK3_1	346	353	PF00069	0.515
MOD_GSK3_1	40	47	PF00069	0.321
MOD_GSK3_1	430	437	PF00069	0.308
MOD_GSK3_1	439	446	PF00069	0.278
MOD_GSK3_1	490	497	PF00069	0.558
MOD_GSK3_1	512	519	PF00069	0.409
MOD_GSK3_1	699	706	PF00069	0.488
MOD_GSK3_1	794	801	PF00069	0.513
MOD_GSK3_1	817	824	PF00069	0.647
MOD_GSK3_1	916	923	PF00069	0.347
MOD_GSK3_1	946	953	PF00069	0.457
MOD_N-GLC_1	563	568	PF02516	0.347
MOD_N-GLC_1	620	625	PF02516	0.258
MOD_N-GLC_2	664	666	PF02516	0.247
MOD_NEK2_1	105	110	PF00069	0.261
MOD_NEK2_1	243	248	PF00069	0.300
MOD_NEK2_1	25	30	PF00069	0.402
MOD_NEK2_1	254	259	PF00069	0.300
MOD_NEK2_1	358	363	PF00069	0.490
MOD_NEK2_1	422	427	PF00069	0.285
MOD_NEK2_1	439	444	PF00069	0.278
MOD_NEK2_1	504	509	PF00069	0.306
MOD_NEK2_1	53	58	PF00069	0.285
MOD_NEK2_1	690	695	PF00069	0.428
MOD_NEK2_1	769	774	PF00069	0.673
MOD_NEK2_1	804	809	PF00069	0.638
MOD_NEK2_1	842	847	PF00069	0.648
MOD_NEK2_1	857	862	PF00069	0.351
MOD_NEK2_1	893	898	PF00069	0.549
MOD_NEK2_1	916	921	PF00069	0.296
MOD_NEK2_1	946	951	PF00069	0.522
MOD_NEK2_2	490	495	PF00069	0.356
MOD_NEK2_2	911	916	PF00069	0.368
MOD_PIKK_1	134	140	PF00454	0.366
MOD_PIKK_1	317	323	PF00454	0.442
MOD_PIKK_1	62	68	PF00454	0.509
MOD_PIKK_1	817	823	PF00454	0.718
MOD_PKA_1	106	112	PF00069	0.379
MOD_PKA_1	699	705	PF00069	0.307
MOD_PKA_2	106	112	PF00069	0.385
MOD_PKA_2	270	276	PF00069	0.516
MOD_PKA_2	494	500	PF00069	0.351
MOD_PKA_2	699	705	PF00069	0.374
MOD_PKA_2	724	730	PF00069	0.588
MOD_PKA_2	821	827	PF00069	0.728
MOD_PKA_2	836	842	PF00069	0.610
MOD_PKA_2	858	864	PF00069	0.441
MOD_PKB_1	701	709	PF00069	0.361
MOD_Plk_1	129	135	PF00069	0.286
MOD_Plk_1	397	403	PF00069	0.407
MOD_Plk_1	422	428	PF00069	0.371
MOD_Plk_1	828	834	PF00069	0.764
MOD_Plk_4	164	170	PF00069	0.360
MOD_Plk_4	238	244	PF00069	0.290
MOD_Plk_4	326	332	PF00069	0.309
MOD_Plk_4	364	370	PF00069	0.424
MOD_Plk_4	434	440	PF00069	0.359
MOD_Plk_4	516	522	PF00069	0.313
MOD_Plk_4	528	534	PF00069	0.221
MOD_Plk_4	545	551	PF00069	0.228
MOD_Plk_4	568	574	PF00069	0.281
MOD_Plk_4	828	834	PF00069	0.691
MOD_Plk_4	836	842	PF00069	0.597
MOD_Plk_4	923	929	PF00069	0.550
MOD_ProDKin_1	249	255	PF00069	0.456
MOD_ProDKin_1	315	321	PF00069	0.598
MOD_ProDKin_1	40	46	PF00069	0.310
MOD_ProDKin_1	430	436	PF00069	0.348
MOD_ProDKin_1	443	449	PF00069	0.284
MOD_ProDKin_1	512	518	PF00069	0.279
MOD_ProDKin_1	580	586	PF00069	0.417
MOD_ProDKin_1	794	800	PF00069	0.575
MOD_ProDKin_1	824	830	PF00069	0.624
MOD_ProDKin_1	894	900	PF00069	0.436
MOD_SUMO_for_1	629	632	PF00179	0.237
MOD_SUMO_rev_2	540	549	PF00179	0.379
MOD_SUMO_rev_2	554	559	PF00179	0.269
MOD_SUMO_rev_2	778	786	PF00179	0.488
TRG_DiLeu_BaEn_2	862	868	PF01217	0.350
TRG_DiLeu_BaEn_4	286	292	PF01217	0.327
TRG_DiLeu_BaEn_4	937	943	PF01217	0.389
TRG_DiLeu_BaLyEn_6	889	894	PF01217	0.401
TRG_DiLeu_BaLyEn_6	904	909	PF01217	0.232
TRG_ENDOCYTIC_2	210	213	PF00928	0.233
TRG_ENDOCYTIC_2	526	529	PF00928	0.233
TRG_ENDOCYTIC_2	677	680	PF00928	0.240
TRG_ENDOCYTIC_2	712	715	PF00928	0.294
TRG_ENDOCYTIC_2	734	737	PF00928	0.660
TRG_ENDOCYTIC_2	877	880	PF00928	0.296
TRG_ENDOCYTIC_2	943	946	PF00928	0.371
TRG_ER_diArg_1	698	701	PF00400	0.459
TRG_ER_diArg_1	722	725	PF00400	0.420
TRG_ER_diArg_1	773	776	PF00400	0.520
TRG_NES_CRM1_1	384	398	PF08389	0.313
TRG_Pf-PMV_PEXEL_1	641	645	PF00026	0.140
TRG_Pf-PMV_PEXEL_1	933	937	PF00026	0.479
TRG_Pf-PMV_PEXEL_1	940	945	PF00026	0.479

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6K3	Leptomonas seymouri	70%	99%
A0A0N1PBH5	Leptomonas seymouri	25%	100%
A0A0P0V4R0	Oryza sativa subsp. japonica	35%	94%
A0A0S4KH73	Bodo saltans	39%	92%
A0A1X0NWG0	Trypanosomatidae	26%	100%
A0A1X0P9Z9	Trypanosomatidae	48%	98%
A0A3R7MDU1	Trypanosoma rangeli	50%	98%
A0A3R7REL5	Trypanosoma rangeli	26%	100%
A0A3R7RLU2	Trypanosoma rangeli	23%	93%
A0A3S7WYU3	Leishmania donovani	25%	100%
A0A3S7X2X3	Leishmania donovani	93%	100%
A1D8E4	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	26%	100%
A3LN13	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	26%	100%
A4HDT9	Leishmania braziliensis	25%	100%
A4HHR4	Leishmania braziliensis	86%	100%
A4I136	Leishmania infantum	25%	100%
A4I4X4	Leishmania infantum	93%	100%
A4K436	Bos taurus	34%	78%
A5DUW8	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	26%	100%
A6ZWN8	Saccharomyces cerevisiae (strain YJM789)	24%	100%
A7UXD4	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	24%	89%
A8MPP1	Homo sapiens	27%	100%
A8WS58	Caenorhabditis briggsae	32%	96%
B0W9F4	Culex quinquefasciatus	32%	97%
B3MSG8	Drosophila ananassae	33%	96%
B3NSW1	Drosophila erecta	33%	97%
B4GU19	Drosophila persimilis	32%	94%
B4JNS2	Drosophila grimshawi	33%	97%
B4NDG5	Drosophila willistoni	33%	95%
B4PZB4	Drosophila yakuba	33%	97%
C9ZKX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	99%
E9AEC8	Leishmania major	92%	100%
E9AX74	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
F1R345	Danio rerio	28%	100%
F4HQE2	Arabidopsis thaliana	35%	92%
O14147	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
P06839	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	100%
P0C928	Danio rerio	34%	81%
P22516	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
Q0VGM9	Mus musculus	34%	79%
Q16X92	Aedes aegypti	32%	94%
Q1E5T3	Coccidioides immitis (strain RS)	28%	100%
Q29FS3	Drosophila pseudoobscura pseudoobscura	32%	94%
Q2U587	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	27%	100%
Q3YK19	Gallus gallus	28%	76%
Q4QAA2	Leishmania major	25%	100%
Q4WWE9	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	26%	100%
Q55G81	Dictyostelium discoideum	26%	100%
Q5RE34	Pongo abelii	34%	73%
Q5RJZ1	Rattus norvegicus	34%	75%
Q6AXC6	Mus musculus	28%	100%
Q6BZD9	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	24%	100%
Q6CAX3	Yarrowia lipolytica (strain CLIB 122 / E 150)	26%	100%
Q6CIF0	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	25%	100%
Q6FKT4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	25%	100%
Q6H1L8	Mus spretus	34%	79%
Q750G3	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	25%	100%
Q7QEI1	Anopheles gambiae	33%	96%
Q92771	Homo sapiens	28%	100%
Q93575	Caenorhabditis elegans	32%	96%
Q96FC9	Homo sapiens	27%	98%
Q9BX63	Homo sapiens	28%	76%
Q9NZ71	Homo sapiens	34%	78%
V5BAP9	Trypanosoma cruzi	28%	100%
V5BX91	Trypanosoma cruzi	49%	100%