Uncharacterized protein LMXM_07_1035

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9ALC1_LEIMU

TriTrypDb:

LmxM.07.1035

Length:

188

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ALC1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALC1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	180	184	PF00082	0.519
CLV_PCSK_SKI1_1	2	6	PF00082	0.783
CLV_PCSK_SKI1_1	9	13	PF00082	0.679
DEG_Nend_UBRbox_1	1	4	PF02207	0.767
DOC_CYCLIN_RxL_1	6	16	PF00134	0.716
DOC_MAPK_gen_1	174	184	PF00069	0.451
DOC_MAPK_MEF2A_6	142	150	PF00069	0.664
DOC_PP2B_LxvP_1	165	168	PF13499	0.678
DOC_PP2B_LxvP_1	82	85	PF13499	0.764
DOC_USP7_MATH_1	63	67	PF00917	0.539
DOC_USP7_MATH_1	91	95	PF00917	0.650
DOC_WW_Pin1_4	18	23	PF00397	0.698
LIG_14-3-3_CanoR_1	149	153	PF00244	0.686
LIG_14-3-3_CanoR_1	154	164	PF00244	0.628
LIG_14-3-3_CanoR_1	6	12	PF00244	0.713
LIG_BRCT_BRCA1_1	58	62	PF00533	0.764
LIG_FHA_1	145	151	PF00498	0.670
LIG_FHA_1	24	30	PF00498	0.672
LIG_FHA_1	40	46	PF00498	0.570
LIG_FHA_1	99	105	PF00498	0.634
LIG_LIR_Gen_1	151	159	PF02991	0.755
LIG_LIR_Nem_3	151	155	PF02991	0.762
LIG_LIR_Nem_3	58	64	PF02991	0.771
LIG_MLH1_MIPbox_1	58	62	PF16413	0.764
LIG_PDZ_Class_1	183	188	PF00595	0.440
LIG_PDZ_Wminus1_1	186	188	PF00595	0.455
LIG_Pex14_2	183	187	PF04695	0.433
LIG_SH2_CRK	152	156	PF00017	0.761
LIG_SH2_CRK	179	183	PF00017	0.710
LIG_SH2_STAP1	100	104	PF00017	0.614
LIG_SH2_STAP1	36	40	PF00017	0.500
LIG_SH2_STAT3	36	39	PF00017	0.459
LIG_SH2_STAT5	100	103	PF00017	0.717
LIG_SH3_3	67	73	PF00018	0.779
LIG_SH3_3	85	91	PF00018	0.651
LIG_SUMO_SIM_par_1	41	46	PF11976	0.672
LIG_TYR_ITIM	150	155	PF00017	0.761
MOD_CDC14_SPxK_1	21	24	PF00782	0.620
MOD_CDK_SPxK_1	18	24	PF00069	0.616
MOD_CK1_1	57	63	PF00069	0.654
MOD_CK1_1	98	104	PF00069	0.488
MOD_GlcNHglycan	139	142	PF01048	0.760
MOD_GlcNHglycan	48	51	PF01048	0.678
MOD_GlcNHglycan	65	68	PF01048	0.568
MOD_GSK3_1	144	151	PF00069	0.652
MOD_GSK3_1	154	161	PF00069	0.646
MOD_GSK3_1	39	46	PF00069	0.607
MOD_GSK3_1	52	59	PF00069	0.625
MOD_GSK3_1	91	98	PF00069	0.565
MOD_NEK2_1	183	188	PF00069	0.654
MOD_NEK2_1	43	48	PF00069	0.629
MOD_NEK2_1	52	57	PF00069	0.634
MOD_NEK2_1	95	100	PF00069	0.457
MOD_PK_1	24	30	PF00069	0.607
MOD_PKA_2	148	154	PF00069	0.763
MOD_PKA_2	155	161	PF00069	0.630
MOD_PKA_2	16	22	PF00069	0.602
MOD_PKA_2	23	29	PF00069	0.521
MOD_Plk_1	158	164	PF00069	0.716
MOD_Plk_1	168	174	PF00069	0.608
MOD_Plk_4	24	30	PF00069	0.704
MOD_Plk_4	57	63	PF00069	0.763
MOD_Plk_4	95	101	PF00069	0.723
MOD_ProDKin_1	18	24	PF00069	0.700
TRG_ENDOCYTIC_2	152	155	PF00928	0.762
TRG_ENDOCYTIC_2	179	182	PF00928	0.635

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HSB8	Leptomonas seymouri	37%	100%
A0A3S5H613	Leishmania donovani	88%	93%
A4H552	Leishmania braziliensis	69%	100%
E9ACQ3	Leishmania major	85%	100%
E9AG77	Leishmania infantum	88%	93%