ATP-dependent DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PIF1 helicase-like protein, putative

Species:

Leishmania mexicana

UniProt:

E9ALB9_LEIMU

TriTrypDb:

LmxM.07.1020

Length:

1218

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	6
GO:0110165	cellular anatomical entity	1	7
GO:0005657	replication fork	2	1
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

E9ALB9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALB9

Function

Biological processes
Term	Name	Level	Count
GO:0000723	telomere maintenance	5	7
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006281	DNA repair	5	7
GO:0006310	DNA recombination	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006950	response to stress	2	7
GO:0006974	DNA damage response	4	7
GO:0006996	organelle organization	4	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0016043	cellular component organization	3	7
GO:0032200	telomere organization	6	7
GO:0033554	cellular response to stress	3	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0050896	response to stimulus	1	7
GO:0051276	chromosome organization	5	7
GO:0051716	cellular response to stimulus	2	7
GO:0071704	organic substance metabolic process	2	7
GO:0071840	cellular component organization or biogenesis	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:0006260	DNA replication	5	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0071103	DNA conformation change	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003678	DNA helicase activity	3	7
GO:0003824	catalytic activity	1	7
GO:0004386	helicase activity	2	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0008094	ATP-dependent activity, acting on DNA	2	7
GO:0016462	pyrophosphatase activity	5	7
GO:0016787	hydrolase activity	2	7
GO:0016817	hydrolase activity, acting on acid anhydrides	3	7
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	7
GO:0016887	ATP hydrolysis activity	7	7
GO:0017076	purine nucleotide binding	4	7
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:0140657	ATP-dependent activity	1	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7
GO:0000287	magnesium ion binding	5	1
GO:0043169	cation binding	3	1
GO:0046872	metal ion binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1042	1046	PF00656	0.653
CLV_C14_Caspase3-7	1211	1215	PF00656	0.587
CLV_C14_Caspase3-7	2	6	PF00656	0.668
CLV_C14_Caspase3-7	330	334	PF00656	0.395
CLV_C14_Caspase3-7	873	877	PF00656	0.663
CLV_NRD_NRD_1	1061	1063	PF00675	0.552
CLV_NRD_NRD_1	19	21	PF00675	0.663
CLV_NRD_NRD_1	211	213	PF00675	0.719
CLV_NRD_NRD_1	407	409	PF00675	0.319
CLV_NRD_NRD_1	475	477	PF00675	0.553
CLV_NRD_NRD_1	597	599	PF00675	0.389
CLV_NRD_NRD_1	784	786	PF00675	0.551
CLV_NRD_NRD_1	870	872	PF00675	0.669
CLV_NRD_NRD_1	874	876	PF00675	0.690
CLV_NRD_NRD_1	886	888	PF00675	0.604
CLV_NRD_NRD_1	941	943	PF00675	0.571
CLV_PCSK_FUR_1	405	409	PF00082	0.395
CLV_PCSK_FUR_1	782	786	PF00082	0.602
CLV_PCSK_KEX2_1	1061	1063	PF00082	0.552
CLV_PCSK_KEX2_1	19	21	PF00082	0.663
CLV_PCSK_KEX2_1	211	213	PF00082	0.719
CLV_PCSK_KEX2_1	407	409	PF00082	0.347
CLV_PCSK_KEX2_1	475	477	PF00082	0.553
CLV_PCSK_KEX2_1	500	502	PF00082	0.624
CLV_PCSK_KEX2_1	784	786	PF00082	0.551
CLV_PCSK_KEX2_1	874	876	PF00082	0.697
CLV_PCSK_KEX2_1	885	887	PF00082	0.620
CLV_PCSK_KEX2_1	940	942	PF00082	0.581
CLV_PCSK_KEX2_1	954	956	PF00082	0.572
CLV_PCSK_PC1ET2_1	500	502	PF00082	0.608
CLV_PCSK_PC1ET2_1	954	956	PF00082	0.551
CLV_PCSK_PC7_1	496	502	PF00082	0.695
CLV_PCSK_PC7_1	780	786	PF00082	0.591
CLV_PCSK_PC7_1	882	888	PF00082	0.612
CLV_PCSK_SKI1_1	1157	1161	PF00082	0.608
CLV_PCSK_SKI1_1	1163	1167	PF00082	0.460
CLV_PCSK_SKI1_1	260	264	PF00082	0.394
CLV_PCSK_SKI1_1	271	275	PF00082	0.258
CLV_PCSK_SKI1_1	602	606	PF00082	0.455
CLV_PCSK_SKI1_1	690	694	PF00082	0.585
CLV_PCSK_SKI1_1	730	734	PF00082	0.559
CLV_PCSK_SKI1_1	80	84	PF00082	0.749
CLV_PCSK_SKI1_1	941	945	PF00082	0.545
CLV_PCSK_SKI1_1	955	959	PF00082	0.628
CLV_Separin_Metazoa	493	497	PF03568	0.583
DEG_APCC_DBOX_1	1053	1061	PF00400	0.492
DEG_SPOP_SBC_1	224	228	PF00917	0.536
DOC_CKS1_1	1	6	PF01111	0.642
DOC_CKS1_1	120	125	PF01111	0.588
DOC_CKS1_1	431	436	PF01111	0.333
DOC_CYCLIN_RxL_1	74	87	PF00134	0.628
DOC_MAPK_DCC_7	659	668	PF00069	0.368
DOC_MAPK_gen_1	1085	1094	PF00069	0.567
DOC_MAPK_gen_1	176	185	PF00069	0.641
DOC_MAPK_gen_1	328	338	PF00069	0.345
DOC_MAPK_gen_1	347	357	PF00069	0.315
DOC_MAPK_gen_1	598	606	PF00069	0.393
DOC_MAPK_gen_1	966	974	PF00069	0.500
DOC_MAPK_MEF2A_6	1112	1119	PF00069	0.541
DOC_MAPK_MEF2A_6	331	340	PF00069	0.345
DOC_MAPK_MEF2A_6	423	430	PF00069	0.317
DOC_MAPK_MEF2A_6	607	615	PF00069	0.561
DOC_MAPK_MEF2A_6	659	668	PF00069	0.365
DOC_MAPK_MEF2A_6	700	708	PF00069	0.355
DOC_PP1_RVXF_1	436	443	PF00149	0.399
DOC_PP1_RVXF_1	468	474	PF00149	0.618
DOC_PP1_RVXF_1	778	784	PF00149	0.496
DOC_PP2B_LxvP_1	38	41	PF13499	0.606
DOC_PP2B_LxvP_1	398	401	PF13499	0.315
DOC_PP4_FxxP_1	121	124	PF00568	0.652
DOC_SPAK_OSR1_1	1112	1116	PF12202	0.588
DOC_USP7_MATH_1	1018	1022	PF00917	0.521
DOC_USP7_MATH_1	1039	1043	PF00917	0.553
DOC_USP7_MATH_1	147	151	PF00917	0.623
DOC_USP7_MATH_1	18	22	PF00917	0.653
DOC_USP7_MATH_1	201	205	PF00917	0.677
DOC_USP7_MATH_1	240	244	PF00917	0.699
DOC_USP7_MATH_1	254	258	PF00917	0.451
DOC_USP7_MATH_1	326	330	PF00917	0.312
DOC_USP7_MATH_1	503	507	PF00917	0.624
DOC_USP7_MATH_1	510	514	PF00917	0.558
DOC_USP7_UBL2_3	868	872	PF12436	0.668
DOC_WW_Pin1_4	1028	1033	PF00397	0.627
DOC_WW_Pin1_4	119	124	PF00397	0.635
DOC_WW_Pin1_4	136	141	PF00397	0.677
DOC_WW_Pin1_4	14	19	PF00397	0.691
DOC_WW_Pin1_4	197	202	PF00397	0.832
DOC_WW_Pin1_4	22	27	PF00397	0.611
DOC_WW_Pin1_4	408	413	PF00397	0.395
DOC_WW_Pin1_4	430	435	PF00397	0.445
DOC_WW_Pin1_4	59	64	PF00397	0.628
DOC_WW_Pin1_4	801	806	PF00397	0.620
DOC_WW_Pin1_4	91	96	PF00397	0.630
DOC_WW_Pin1_4	941	946	PF00397	0.534
LIG_14-3-3_CanoR_1	1112	1118	PF00244	0.559
LIG_14-3-3_CanoR_1	1199	1204	PF00244	0.503
LIG_14-3-3_CanoR_1	19	24	PF00244	0.664
LIG_14-3-3_CanoR_1	192	196	PF00244	0.549
LIG_14-3-3_CanoR_1	211	215	PF00244	0.758
LIG_14-3-3_CanoR_1	253	263	PF00244	0.345
LIG_14-3-3_CanoR_1	347	357	PF00244	0.220
LIG_14-3-3_CanoR_1	475	483	PF00244	0.626
LIG_14-3-3_CanoR_1	567	576	PF00244	0.570
LIG_14-3-3_CanoR_1	659	663	PF00244	0.396
LIG_14-3-3_CanoR_1	744	751	PF00244	0.402
LIG_14-3-3_CanoR_1	760	764	PF00244	0.394
LIG_14-3-3_CanoR_1	845	854	PF00244	0.664
LIG_14-3-3_CanoR_1	90	95	PF00244	0.720
LIG_BIR_III_2	236	240	PF00653	0.515
LIG_BIR_III_4	1140	1144	PF00653	0.610
LIG_BIR_III_4	5	9	PF00653	0.653
LIG_BRCT_BRCA1_1	110	114	PF00533	0.493
LIG_BRCT_BRCA1_1	296	300	PF00533	0.315
LIG_BRCT_BRCA1_1	393	397	PF00533	0.317
LIG_BRCT_BRCA1_1	410	414	PF00533	0.434
LIG_BRCT_BRCA1_1	431	435	PF00533	0.315
LIG_BRCT_BRCA1_1	829	833	PF00533	0.592
LIG_CtBP_PxDLS_1	135	139	PF00389	0.540
LIG_deltaCOP1_diTrp_1	1107	1113	PF00928	0.543
LIG_DLG_GKlike_1	1199	1206	PF00625	0.505
LIG_FHA_1	1098	1104	PF00498	0.591
LIG_FHA_1	1112	1118	PF00498	0.560
LIG_FHA_1	1182	1188	PF00498	0.485
LIG_FHA_1	168	174	PF00498	0.554
LIG_FHA_1	30	36	PF00498	0.715
LIG_FHA_1	302	308	PF00498	0.345
LIG_FHA_1	349	355	PF00498	0.430
LIG_FHA_1	466	472	PF00498	0.501
LIG_FHA_1	590	596	PF00498	0.476
LIG_FHA_1	618	624	PF00498	0.424
LIG_FHA_1	629	635	PF00498	0.573
LIG_FHA_1	677	683	PF00498	0.473
LIG_FHA_1	931	937	PF00498	0.583
LIG_FHA_1	942	948	PF00498	0.564
LIG_FHA_1	956	962	PF00498	0.549
LIG_FHA_2	203	209	PF00498	0.671
LIG_FHA_2	225	231	PF00498	0.625
LIG_FHA_2	37	43	PF00498	0.811
LIG_FHA_2	527	533	PF00498	0.656
LIG_FHA_2	552	558	PF00498	0.421
LIG_FHA_2	620	626	PF00498	0.571
LIG_FHA_2	676	682	PF00498	0.387
LIG_FHA_2	721	727	PF00498	0.583
LIG_FHA_2	744	750	PF00498	0.371
LIG_Integrin_RGD_1	1054	1056	PF01839	0.525
LIG_LIR_Apic_2	119	124	PF02991	0.648
LIG_LIR_Apic_2	89	95	PF02991	0.669
LIG_LIR_Gen_1	1107	1118	PF02991	0.546
LIG_LIR_Gen_1	366	375	PF02991	0.294
LIG_LIR_Gen_1	394	403	PF02991	0.315
LIG_LIR_Gen_1	546	556	PF02991	0.420
LIG_LIR_Gen_1	624	634	PF02991	0.430
LIG_LIR_LC3C_4	679	684	PF02991	0.505
LIG_LIR_Nem_3	1045	1050	PF02991	0.512
LIG_LIR_Nem_3	1107	1113	PF02991	0.565
LIG_LIR_Nem_3	111	117	PF02991	0.483
LIG_LIR_Nem_3	1167	1171	PF02991	0.501
LIG_LIR_Nem_3	364	370	PF02991	0.315
LIG_LIR_Nem_3	384	389	PF02991	0.183
LIG_LIR_Nem_3	394	400	PF02991	0.315
LIG_LIR_Nem_3	418	424	PF02991	0.314
LIG_LIR_Nem_3	448	454	PF02991	0.400
LIG_LIR_Nem_3	542	548	PF02991	0.478
LIG_LIR_Nem_3	575	579	PF02991	0.384
LIG_LIR_Nem_3	624	629	PF02991	0.394
LIG_LIR_Nem_3	726	732	PF02991	0.391
LIG_LIR_Nem_3	738	742	PF02991	0.439
LIG_LIR_Nem_3	769	774	PF02991	0.304
LIG_LIR_Nem_3	804	809	PF02991	0.513
LIG_LIR_Nem_3	830	836	PF02991	0.676
LIG_PDZ_Class_2	1213	1218	PF00595	0.593
LIG_Pex14_2	729	733	PF04695	0.410
LIG_Pex14_2	829	833	PF04695	0.592
LIG_Pex14_2	992	996	PF04695	0.527
LIG_SH2_CRK	548	552	PF00017	0.400
LIG_SH2_CRK	771	775	PF00017	0.416
LIG_SH2_CRK	806	810	PF00017	0.554
LIG_SH2_CRK	92	96	PF00017	0.677
LIG_SH2_NCK_1	92	96	PF00017	0.677
LIG_SH2_PTP2	739	742	PF00017	0.358
LIG_SH2_PTP2	808	811	PF00017	0.548
LIG_SH2_STAP1	110	114	PF00017	0.493
LIG_SH2_STAP1	1168	1172	PF00017	0.526
LIG_SH2_STAP1	1192	1196	PF00017	0.517
LIG_SH2_STAP1	261	265	PF00017	0.315
LIG_SH2_STAP1	710	714	PF00017	0.350
LIG_SH2_STAT3	565	568	PF00017	0.519
LIG_SH2_STAT5	1171	1174	PF00017	0.570
LIG_SH2_STAT5	1205	1208	PF00017	0.639
LIG_SH2_STAT5	373	376	PF00017	0.335
LIG_SH2_STAT5	548	551	PF00017	0.423
LIG_SH2_STAT5	633	636	PF00017	0.526
LIG_SH2_STAT5	739	742	PF00017	0.383
LIG_SH2_STAT5	808	811	PF00017	0.548
LIG_SH2_STAT5	92	95	PF00017	0.675
LIG_SH3_1	379	385	PF00018	0.315
LIG_SH3_3	1029	1035	PF00018	0.637
LIG_SH3_3	1091	1097	PF00018	0.583
LIG_SH3_3	1112	1118	PF00018	0.605
LIG_SH3_3	117	123	PF00018	0.615
LIG_SH3_3	12	18	PF00018	0.731
LIG_SH3_3	139	145	PF00018	0.803
LIG_SH3_3	20	26	PF00018	0.680
LIG_SH3_3	236	242	PF00018	0.813
LIG_SH3_3	379	385	PF00018	0.323
LIG_SH3_3	680	686	PF00018	0.406
LIG_SH3_3	699	705	PF00018	0.356
LIG_SH3_3	70	76	PF00018	0.714
LIG_SH3_3	980	986	PF00018	0.616
LIG_SUMO_SIM_anti_2	1078	1084	PF11976	0.517
LIG_SUMO_SIM_anti_2	333	341	PF11976	0.345
LIG_SUMO_SIM_anti_2	457	464	PF11976	0.418
LIG_SUMO_SIM_anti_2	529	535	PF11976	0.613
LIG_SUMO_SIM_par_1	116	122	PF11976	0.570
LIG_SUMO_SIM_par_1	25	33	PF11976	0.651
LIG_SUMO_SIM_par_1	353	359	PF11976	0.395
LIG_TRAF2_1	100	103	PF00917	0.518
LIG_TRAF2_1	793	796	PF00917	0.554
LIG_TYR_ITSM	802	809	PF00017	0.494
LIG_UBA3_1	335	342	PF00899	0.345
LIG_WRC_WIRS_1	317	322	PF05994	0.315
LIG_WRC_WIRS_1	626	631	PF05994	0.421
LIG_WRC_WIRS_1	833	838	PF05994	0.653
MOD_CDC14_SPxK_1	17	20	PF00782	0.651
MOD_CDK_SPK_2	14	19	PF00069	0.692
MOD_CDK_SPxK_1	14	20	PF00069	0.656
MOD_CDK_SPxK_1	430	436	PF00069	0.333
MOD_CK1_1	109	115	PF00069	0.582
MOD_CK1_1	116	122	PF00069	0.632
MOD_CK1_1	150	156	PF00069	0.700
MOD_CK1_1	187	193	PF00069	0.637
MOD_CK1_1	197	203	PF00069	0.812
MOD_CK1_1	22	28	PF00069	0.521
MOD_CK1_1	313	319	PF00069	0.287
MOD_CK1_1	327	333	PF00069	0.361
MOD_CK1_1	334	340	PF00069	0.445
MOD_CK1_1	464	470	PF00069	0.473
MOD_CK1_1	52	58	PF00069	0.625
MOD_CK1_1	522	528	PF00069	0.670
MOD_CK1_1	619	625	PF00069	0.387
MOD_CK1_1	628	634	PF00069	0.451
MOD_CK1_1	66	72	PF00069	0.648
MOD_CK1_1	735	741	PF00069	0.410
MOD_CK1_1	743	749	PF00069	0.361
MOD_CK1_1	827	833	PF00069	0.642
MOD_CK1_1	837	843	PF00069	0.657
MOD_CK1_1	84	90	PF00069	0.661
MOD_CK1_1	844	850	PF00069	0.592
MOD_CK1_1	94	100	PF00069	0.714
MOD_CK2_1	1018	1024	PF00069	0.544
MOD_CK2_1	1172	1178	PF00069	0.536
MOD_CK2_1	163	169	PF00069	0.717
MOD_CK2_1	202	208	PF00069	0.795
MOD_CK2_1	27	33	PF00069	0.648
MOD_CK2_1	358	364	PF00069	0.315
MOD_CK2_1	36	42	PF00069	0.672
MOD_CK2_1	526	532	PF00069	0.657
MOD_CK2_1	551	557	PF00069	0.418
MOD_CK2_1	675	681	PF00069	0.474
MOD_CK2_1	743	749	PF00069	0.367
MOD_GlcNHglycan	1209	1213	PF01048	0.722
MOD_GlcNHglycan	149	152	PF01048	0.675
MOD_GlcNHglycan	188	192	PF01048	0.616
MOD_GlcNHglycan	242	245	PF01048	0.610
MOD_GlcNHglycan	312	315	PF01048	0.332
MOD_GlcNHglycan	393	396	PF01048	0.315
MOD_GlcNHglycan	504	508	PF01048	0.638
MOD_GlcNHglycan	512	515	PF01048	0.548
MOD_GlcNHglycan	520	524	PF01048	0.586
MOD_GlcNHglycan	640	643	PF01048	0.461
MOD_GlcNHglycan	734	737	PF01048	0.453
MOD_GlcNHglycan	826	829	PF01048	0.515
MOD_GlcNHglycan	846	849	PF01048	0.498
MOD_GlcNHglycan	987	990	PF01048	0.529
MOD_GSK3_1	1018	1025	PF00069	0.540
MOD_GSK3_1	106	113	PF00069	0.564
MOD_GSK3_1	14	21	PF00069	0.616
MOD_GSK3_1	152	159	PF00069	0.650
MOD_GSK3_1	163	170	PF00069	0.585
MOD_GSK3_1	187	194	PF00069	0.609
MOD_GSK3_1	197	204	PF00069	0.841
MOD_GSK3_1	210	217	PF00069	0.620
MOD_GSK3_1	25	32	PF00069	0.625
MOD_GSK3_1	269	276	PF00069	0.434
MOD_GSK3_1	312	319	PF00069	0.428
MOD_GSK3_1	327	334	PF00069	0.381
MOD_GSK3_1	461	468	PF00069	0.427
MOD_GSK3_1	474	481	PF00069	0.575
MOD_GSK3_1	519	526	PF00069	0.665
MOD_GSK3_1	52	59	PF00069	0.627
MOD_GSK3_1	546	553	PF00069	0.405
MOD_GSK3_1	568	575	PF00069	0.396
MOD_GSK3_1	617	624	PF00069	0.395
MOD_GSK3_1	634	641	PF00069	0.450
MOD_GSK3_1	692	699	PF00069	0.597
MOD_GSK3_1	710	717	PF00069	0.373
MOD_GSK3_1	743	750	PF00069	0.515
MOD_GSK3_1	759	766	PF00069	0.344
MOD_GSK3_1	823	830	PF00069	0.656
MOD_GSK3_1	832	839	PF00069	0.616
MOD_GSK3_1	840	847	PF00069	0.562
MOD_GSK3_1	90	97	PF00069	0.759
MOD_LATS_1	161	167	PF00433	0.598
MOD_N-GLC_1	310	315	PF02516	0.315
MOD_N-GLC_1	616	621	PF02516	0.411
MOD_N-GLC_1	763	768	PF02516	0.317
MOD_N-GLC_1	862	867	PF02516	0.522
MOD_N-GLC_1	930	935	PF02516	0.644
MOD_NEK2_1	1026	1031	PF00069	0.581
MOD_NEK2_1	1070	1075	PF00069	0.597
MOD_NEK2_1	108	113	PF00069	0.705
MOD_NEK2_1	1111	1116	PF00069	0.589
MOD_NEK2_1	1172	1177	PF00069	0.496
MOD_NEK2_1	27	32	PF00069	0.654
MOD_NEK2_1	286	291	PF00069	0.395
MOD_NEK2_1	310	315	PF00069	0.315
MOD_NEK2_1	521	526	PF00069	0.667
MOD_NEK2_1	551	556	PF00069	0.431
MOD_NEK2_1	56	61	PF00069	0.618
MOD_NEK2_1	634	639	PF00069	0.457
MOD_NEK2_1	68	73	PF00069	0.630
MOD_NEK2_1	720	725	PF00069	0.442
MOD_NEK2_1	82	87	PF00069	0.653
MOD_NEK2_1	836	841	PF00069	0.661
MOD_NEK2_1	930	935	PF00069	0.679
MOD_NEK2_1	946	951	PF00069	0.464
MOD_NEK2_2	156	161	PF00069	0.597
MOD_NEK2_2	710	715	PF00069	0.357
MOD_OFUCOSY	345	352	PF10250	0.345
MOD_PIKK_1	1024	1030	PF00454	0.625
MOD_PIKK_1	634	640	PF00454	0.482
MOD_PIKK_1	714	720	PF00454	0.412
MOD_PIKK_1	880	886	PF00454	0.678
MOD_PK_1	19	25	PF00069	0.665
MOD_PK_1	455	461	PF00069	0.323
MOD_PKA_1	19	25	PF00069	0.665
MOD_PKA_1	407	413	PF00069	0.395
MOD_PKA_2	1111	1117	PF00069	0.576
MOD_PKA_2	18	24	PF00069	0.736
MOD_PKA_2	191	197	PF00069	0.521
MOD_PKA_2	210	216	PF00069	0.658
MOD_PKA_2	327	333	PF00069	0.395
MOD_PKA_2	407	413	PF00069	0.395
MOD_PKA_2	474	480	PF00069	0.641
MOD_PKA_2	526	532	PF00069	0.689
MOD_PKA_2	551	557	PF00069	0.418
MOD_PKA_2	658	664	PF00069	0.410
MOD_PKA_2	743	749	PF00069	0.399
MOD_PKA_2	759	765	PF00069	0.410
MOD_PKA_2	824	830	PF00069	0.698
MOD_PKA_2	844	850	PF00069	0.501
MOD_PKA_2	967	973	PF00069	0.536
MOD_PKB_1	1197	1205	PF00069	0.576
MOD_PKB_1	405	413	PF00069	0.395
MOD_Plk_1	358	364	PF00069	0.315
MOD_Plk_1	587	593	PF00069	0.519
MOD_Plk_1	763	769	PF00069	0.324
MOD_Plk_1	862	868	PF00069	0.523
MOD_Plk_1	901	907	PF00069	0.529
MOD_Plk_1	930	936	PF00069	0.670
MOD_Plk_2-3	167	173	PF00069	0.531
MOD_Plk_2-3	358	364	PF00069	0.315
MOD_Plk_4	1008	1014	PF00069	0.609
MOD_Plk_4	113	119	PF00069	0.664
MOD_Plk_4	1183	1189	PF00069	0.486
MOD_Plk_4	296	302	PF00069	0.324
MOD_Plk_4	316	322	PF00069	0.196
MOD_Plk_4	331	337	PF00069	0.361
MOD_Plk_4	358	364	PF00069	0.315
MOD_Plk_4	546	552	PF00069	0.409
MOD_Plk_4	658	664	PF00069	0.410
MOD_Plk_4	735	741	PF00069	0.490
MOD_Plk_4	766	772	PF00069	0.289
MOD_ProDKin_1	1028	1034	PF00069	0.631
MOD_ProDKin_1	119	125	PF00069	0.636
MOD_ProDKin_1	136	142	PF00069	0.672
MOD_ProDKin_1	14	20	PF00069	0.693
MOD_ProDKin_1	197	203	PF00069	0.832
MOD_ProDKin_1	22	28	PF00069	0.610
MOD_ProDKin_1	408	414	PF00069	0.395
MOD_ProDKin_1	430	436	PF00069	0.445
MOD_ProDKin_1	59	65	PF00069	0.631
MOD_ProDKin_1	801	807	PF00069	0.630
MOD_ProDKin_1	91	97	PF00069	0.632
MOD_ProDKin_1	941	947	PF00069	0.534
MOD_SUMO_for_1	454	457	PF00179	0.313
MOD_SUMO_for_1	483	486	PF00179	0.579
MOD_SUMO_for_1	499	502	PF00179	0.549
MOD_SUMO_for_1	854	857	PF00179	0.677
MOD_SUMO_rev_2	447	456	PF00179	0.283
MOD_SUMO_rev_2	726	732	PF00179	0.421
TRG_DiLeu_BaEn_1	103	108	PF01217	0.643
TRG_DiLeu_BaEn_1	457	462	PF01217	0.323
TRG_DiLeu_BaEn_2	468	474	PF01217	0.618
TRG_DiLeu_BaLyEn_6	1115	1120	PF01217	0.543
TRG_DiLeu_BaLyEn_6	702	707	PF01217	0.429
TRG_DiLeu_BaLyEn_6	942	947	PF01217	0.564
TRG_ENDOCYTIC_2	182	185	PF00928	0.619
TRG_ENDOCYTIC_2	548	551	PF00928	0.400
TRG_ENDOCYTIC_2	576	579	PF00928	0.524
TRG_ENDOCYTIC_2	739	742	PF00928	0.358
TRG_ENDOCYTIC_2	771	774	PF00928	0.409
TRG_ENDOCYTIC_2	806	809	PF00928	0.531
TRG_ER_diArg_1	1060	1062	PF00400	0.529
TRG_ER_diArg_1	1120	1123	PF00400	0.583
TRG_ER_diArg_1	1196	1199	PF00400	0.576
TRG_ER_diArg_1	18	20	PF00400	0.651
TRG_ER_diArg_1	378	381	PF00400	0.319
TRG_ER_diArg_1	435	438	PF00400	0.315
TRG_ER_diArg_1	474	476	PF00400	0.548
TRG_ER_diArg_1	780	783	PF00400	0.503
TRG_ER_diArg_1	885	887	PF00400	0.730
TRG_ER_diArg_1	939	942	PF00400	0.578
TRG_ER_FFAT_2	86	97	PF00635	0.606
TRG_Pf-PMV_PEXEL_1	1163	1167	PF00026	0.507
TRG_Pf-PMV_PEXEL_1	163	167	PF00026	0.700
TRG_Pf-PMV_PEXEL_1	253	258	PF00026	0.345
TRG_Pf-PMV_PEXEL_1	353	358	PF00026	0.340
TRG_Pf-PMV_PEXEL_1	567	572	PF00026	0.437
TRG_Pf-PMV_PEXEL_1	680	685	PF00026	0.491
TRG_Pf-PMV_PEXEL_1	971	975	PF00026	0.425

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3C2	Leptomonas seymouri	55%	98%
A0A3S7WQ25	Leishmania donovani	88%	100%
A4H550	Leishmania braziliensis	70%	100%
A4HTC6	Leishmania infantum	88%	100%
Q4QII5	Leishmania major	86%	100%