Putative serine/threonine kinase (Putative protein kinase)

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

serine/threonine kinase, putative

Species:

Leishmania mexicana

UniProt:

E9ALA7_LEIMU

TriTrypDb:

LmxM.07.0900

Length:

296

Annotations

LeishMANIAdb annotations

A large and apprently artificial collection of diverse kinetoplastid protein kinases. None of them appear to be TM.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 25
NetGPI	no	yes: 0, no: 25

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0097014	ciliary plasm	5	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	2
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1

Expansion

Sequence features

E9ALA7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ALA7

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	26
GO:0006793	phosphorus metabolic process	3	26
GO:0006796	phosphate-containing compound metabolic process	4	26
GO:0006807	nitrogen compound metabolic process	2	26
GO:0008152	metabolic process	1	26
GO:0009987	cellular process	1	26
GO:0016310	phosphorylation	5	26
GO:0019538	protein metabolic process	3	26
GO:0036211	protein modification process	4	26
GO:0043170	macromolecule metabolic process	3	26
GO:0043412	macromolecule modification	4	26
GO:0044237	cellular metabolic process	2	26
GO:0044238	primary metabolic process	2	26
GO:0071704	organic substance metabolic process	2	26
GO:1901564	organonitrogen compound metabolic process	3	26
GO:0007165	signal transduction	2	2
GO:0035556	intracellular signal transduction	3	2
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0065007	biological regulation	1	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	26
GO:0003824	catalytic activity	1	26
GO:0004672	protein kinase activity	3	26
GO:0004674	protein serine/threonine kinase activity	4	26
GO:0005488	binding	1	26
GO:0005524	ATP binding	5	26
GO:0016301	kinase activity	4	26
GO:0016740	transferase activity	2	26
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	26
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	26
GO:0017076	purine nucleotide binding	4	26
GO:0030554	adenyl nucleotide binding	5	26
GO:0032553	ribonucleotide binding	3	26
GO:0032555	purine ribonucleotide binding	4	26
GO:0032559	adenyl ribonucleotide binding	5	26
GO:0035639	purine ribonucleoside triphosphate binding	4	26
GO:0036094	small molecule binding	2	26
GO:0043167	ion binding	2	26
GO:0043168	anion binding	3	26
GO:0097159	organic cyclic compound binding	2	26
GO:0097367	carbohydrate derivative binding	2	26
GO:0140096	catalytic activity, acting on a protein	2	26
GO:1901265	nucleoside phosphate binding	3	26
GO:1901363	heterocyclic compound binding	2	26

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	103	105	PF00082	0.277
CLV_PCSK_KEX2_1	5	7	PF00082	0.436
CLV_PCSK_KEX2_1	56	58	PF00082	0.282
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.277
CLV_PCSK_PC1ET2_1	5	7	PF00082	0.413
CLV_PCSK_PC1ET2_1	56	58	PF00082	0.306
CLV_PCSK_SKI1_1	132	136	PF00082	0.265
CLV_PCSK_SKI1_1	245	249	PF00082	0.302
DEG_APCC_DBOX_1	253	261	PF00400	0.300
DOC_MAPK_gen_1	132	141	PF00069	0.265
DOC_MAPK_gen_1	63	73	PF00069	0.289
DOC_MAPK_JIP1_4	135	141	PF00069	0.277
DOC_PP4_FxxP_1	105	108	PF00568	0.309
DOC_USP7_MATH_2	251	257	PF00917	0.409
DOC_USP7_UBL2_3	39	43	PF12436	0.271
DOC_USP7_UBL2_3	5	9	PF12436	0.425
DOC_WW_Pin1_4	171	176	PF00397	0.280
DOC_WW_Pin1_4	280	285	PF00397	0.660
LIG_14-3-3_CanoR_1	159	163	PF00244	0.250
LIG_14-3-3_CanoR_1	233	242	PF00244	0.307
LIG_14-3-3_CanoR_1	245	250	PF00244	0.257
LIG_14-3-3_CanoR_1	254	258	PF00244	0.260
LIG_deltaCOP1_diTrp_1	194	203	PF00928	0.271
LIG_EH1_1	83	91	PF00400	0.319
LIG_eIF4E_1	112	118	PF01652	0.254
LIG_eIF4E_1	84	90	PF01652	0.319
LIG_FHA_1	144	150	PF00498	0.295
LIG_FHA_1	284	290	PF00498	0.663
LIG_FHA_2	220	226	PF00498	0.311
LIG_FHA_2	274	280	PF00498	0.575
LIG_FHA_2	30	36	PF00498	0.287
LIG_FHA_2	89	95	PF00498	0.343
LIG_LIR_Apic_2	174	180	PF02991	0.265
LIG_LIR_Gen_1	18	27	PF02991	0.279
LIG_LIR_Gen_1	94	102	PF02991	0.269
LIG_LIR_Nem_3	18	24	PF02991	0.272
LIG_LIR_Nem_3	185	191	PF02991	0.292
LIG_LIR_Nem_3	94	99	PF02991	0.251
LIG_Pex14_2	266	270	PF04695	0.352
LIG_RPA_C_Fungi	228	240	PF08784	0.409
LIG_SH2_CRK	188	192	PF00017	0.277
LIG_SH2_PTP2	177	180	PF00017	0.265
LIG_SH2_STAT3	113	116	PF00017	0.265
LIG_SH2_STAT5	113	116	PF00017	0.265
LIG_SH2_STAT5	123	126	PF00017	0.265
LIG_SH2_STAT5	177	180	PF00017	0.272
LIG_SH2_STAT5	209	212	PF00017	0.273
LIG_SH2_STAT5	84	87	PF00017	0.265
LIG_SUMO_SIM_anti_2	58	63	PF11976	0.271
LIG_SUMO_SIM_par_1	244	250	PF11976	0.291
LIG_SUMO_SIM_par_1	69	75	PF11976	0.243
LIG_SUMO_SIM_par_1	85	91	PF11976	0.343
LIG_UBA3_1	95	103	PF00899	0.265
MOD_CK1_1	160	166	PF00069	0.425
MOD_CK1_1	280	286	PF00069	0.677
MOD_CK2_1	219	225	PF00069	0.320
MOD_CK2_1	273	279	PF00069	0.541
MOD_CK2_1	29	35	PF00069	0.287
MOD_CK2_1	88	94	PF00069	0.319
MOD_GlcNHglycan	100	103	PF01048	0.358
MOD_GlcNHglycan	162	165	PF01048	0.384
MOD_GlcNHglycan	235	238	PF01048	0.372
MOD_GSK3_1	143	150	PF00069	0.287
MOD_GSK3_1	15	22	PF00069	0.277
MOD_GSK3_1	163	170	PF00069	0.134
MOD_GSK3_1	241	248	PF00069	0.313
MOD_GSK3_1	273	280	PF00069	0.544
MOD_GSK3_1	283	290	PF00069	0.642
MOD_N-GLC_1	143	148	PF02516	0.300
MOD_N-GLC_1	19	24	PF02516	0.292
MOD_N-GLC_2	122	124	PF02516	0.343
MOD_NEK2_1	12	17	PF00069	0.298
MOD_NEK2_1	152	157	PF00069	0.289
MOD_NEK2_1	167	172	PF00069	0.217
MOD_NEK2_1	77	82	PF00069	0.343
MOD_NEK2_2	143	148	PF00069	0.327
MOD_PIKK_1	273	279	PF00454	0.507
MOD_PIKK_1	284	290	PF00454	0.659
MOD_PKA_2	158	164	PF00069	0.382
MOD_PKA_2	253	259	PF00069	0.296
MOD_PKA_2	27	33	PF00069	0.372
MOD_Plk_1	143	149	PF00069	0.315
MOD_Plk_1	284	290	PF00069	0.655
MOD_Plk_2-3	253	259	PF00069	0.409
MOD_Plk_4	163	169	PF00069	0.288
MOD_ProDKin_1	171	177	PF00069	0.280
MOD_ProDKin_1	280	286	PF00069	0.660
MOD_SUMO_for_1	134	137	PF00179	0.265
MOD_SUMO_for_1	55	58	PF00179	0.287
TRG_ENDOCYTIC_2	188	191	PF00928	0.276
TRG_ENDOCYTIC_2	209	212	PF00928	0.273
TRG_ENDOCYTIC_2	84	87	PF00928	0.265
TRG_NES_CRM1_1	53	67	PF08389	0.272
TRG_Pf-PMV_PEXEL_1	132	137	PF00026	0.265
TRG_Pf-PMV_PEXEL_1	245	250	PF00026	0.329

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P215	Leptomonas seymouri	31%	100%
A0A0N0P3N5	Leptomonas seymouri	33%	69%
A0A0N0P4J7	Leptomonas seymouri	27%	67%
A0A0N0P787	Leptomonas seymouri	34%	77%
A0A0N0P8H5	Leptomonas seymouri	33%	89%
A0A0N1HWQ2	Leptomonas seymouri	33%	98%
A0A0N1I6T8	Leptomonas seymouri	93%	100%
A0A0N1IIF9	Leptomonas seymouri	67%	100%
A0A0N1IM47	Leptomonas seymouri	32%	81%
A0A0N1IMI0	Leptomonas seymouri	26%	100%
A0A0N1PC31	Leptomonas seymouri	33%	76%
A0A0N1PC32	Leptomonas seymouri	33%	76%
A0A0N1PD05	Leptomonas seymouri	30%	66%
A0A0N1PDW7	Leptomonas seymouri	39%	75%
A0A0S4IMB7	Bodo saltans	31%	67%
A0A0S4IRU8	Bodo saltans	32%	69%
A0A0S4IX86	Bodo saltans	32%	69%
A0A0S4IZY3	Bodo saltans	35%	88%
A0A0S4J3Y5	Bodo saltans	31%	69%
A0A0S4J4B3	Bodo saltans	72%	66%
A0A0S4J4X4	Bodo saltans	32%	98%
A0A0S4J6L4	Bodo saltans	33%	78%
A0A0S4JA09	Bodo saltans	32%	72%
A0A0S4JBR3	Bodo saltans	33%	94%
A0A0S4JCG2	Bodo saltans	63%	66%
A0A0S4JF22	Bodo saltans	29%	83%
A0A0S4JK24	Bodo saltans	31%	68%
A0A0S4JPZ7	Bodo saltans	30%	71%
A0A0S4JUJ2	Bodo saltans	35%	100%
A0A0S4JWD5	Bodo saltans	34%	76%
A0A0S4KFT7	Bodo saltans	33%	88%
A0A0S4KMV7	Bodo saltans	41%	92%
A0A0S4KN74	Bodo saltans	32%	91%
A0A1X0NIA0	Trypanosomatidae	31%	69%
A0A1X0NIX2	Trypanosomatidae	29%	67%
A0A1X0NKA1	Trypanosomatidae	31%	67%
A0A1X0NQ63	Trypanosomatidae	76%	100%
A0A1X0NRZ9	Trypanosomatidae	28%	80%
A0A1X0NTR6	Trypanosomatidae	38%	84%
A0A1X0NUQ4	Trypanosomatidae	34%	78%
A0A1X0NY93	Trypanosomatidae	32%	76%
A0A1X0NYK8	Trypanosomatidae	32%	96%
A0A1X0NYQ8	Trypanosomatidae	28%	94%
A0A1X0P527	Trypanosomatidae	29%	67%
A0A1X0P5B1	Trypanosomatidae	37%	90%
A0A1X0P5F2	Trypanosomatidae	37%	90%
A0A1X0P692	Trypanosomatidae	31%	82%
A0A1X0P6V1	Trypanosomatidae	64%	100%
A0A1X0P735	Trypanosomatidae	65%	100%
A0A1X0P7V0	Trypanosomatidae	35%	88%
A0A1X0P8A0	Trypanosomatidae	29%	95%
A0A1X0P8F7	Trypanosomatidae	29%	68%
A0A3Q8IAQ1	Leishmania donovani	34%	83%
A0A3Q8IB30	Leishmania donovani	33%	89%
A0A3Q8IB74	Leishmania donovani	25%	100%
A0A3Q8IBT5	Leishmania donovani	26%	100%
A0A3Q8IC87	Leishmania donovani	38%	80%
A0A3Q8IEH3	Leishmania donovani	33%	98%
A0A3Q8IFK8	Leishmania donovani	30%	67%
A0A3Q8IFW0	Leishmania donovani	32%	69%
A0A3Q8IH39	Leishmania donovani	28%	100%
A0A3Q8INQ4	Leishmania donovani	33%	76%
A0A3Q8INS5	Leishmania donovani	26%	99%
A0A3Q8ITZ9	Leishmania donovani	23%	100%
A0A3R7K5P9	Trypanosoma rangeli	38%	79%
A0A3R7KCZ4	Trypanosoma rangeli	29%	73%
A0A3R7M5C7	Trypanosoma rangeli	78%	100%
A0A3R7MHW5	Trypanosoma rangeli	34%	74%
A0A3R7MJP3	Trypanosoma rangeli	29%	100%
A0A3R7MKG5	Trypanosoma rangeli	28%	67%
A0A3R7N4D8	Trypanosoma rangeli	31%	73%
A0A3R7N5S4	Trypanosoma rangeli	34%	78%
A0A3R7NKI8	Trypanosoma rangeli	29%	95%
A0A3R7RLL1	Trypanosoma rangeli	27%	68%
A0A3S5H5G0	Leishmania donovani	26%	100%
A0A3S5H606	Leishmania donovani	98%	100%
A0A3S5H789	Leishmania donovani	25%	100%
A0A3S7WR45	Leishmania donovani	26%	100%
A0A3S7WRG1	Leishmania donovani	25%	100%
A0A3S7WTN9	Leishmania donovani	33%	77%
A0A3S7WUX5	Leishmania donovani	66%	100%
A0A3S7WVE9	Leishmania donovani	31%	100%
A0A3S7WWE7	Leishmania donovani	26%	100%
A0A3S7WWL1	Leishmania donovani	26%	99%
A0A3S7X123	Leishmania donovani	26%	100%
A0A3S7X2W9	Leishmania donovani	26%	100%
A0A3S7X6T8	Leishmania donovani	32%	66%
A0A3S7X7D5	Leishmania donovani	25%	100%
A0A3S7X9R4	Leishmania donovani	35%	80%
A0A3S7X9S2	Leishmania donovani	35%	87%
A0A3S7XA45	Leishmania donovani	33%	76%
A0A422MYB4	Trypanosoma rangeli	36%	94%
A0A422NJ21	Trypanosoma rangeli	60%	100%
A0A422NJ30	Trypanosoma rangeli	62%	100%
A0A422NUF0	Trypanosoma rangeli	30%	74%
A0A422P0J2	Trypanosoma rangeli	38%	88%
A0A422P0N6	Trypanosoma rangeli	29%	95%
A0A422P1R5	Trypanosoma rangeli	33%	96%
A0A422P270	Trypanosoma rangeli	29%	67%
A0A451EJH2	Leishmania donovani	25%	100%
A0A8I3S724	Canis lupus familiaris	37%	73%
A2YNT8	Oryza sativa subsp. indica	43%	87%
A2ZAB5	Oryza sativa subsp. indica	40%	89%
A3B529	Oryza sativa subsp. japonica	52%	68%
A4H3D2	Leishmania braziliensis	25%	100%
A4H459	Leishmania braziliensis	26%	100%
A4H539	Leishmania braziliensis	95%	100%
A4H601	Leishmania braziliensis	29%	100%
A4H641	Leishmania braziliensis	26%	100%
A4H8C4	Leishmania braziliensis	32%	100%
A4H9H4	Leishmania braziliensis	65%	100%
A4H9L8	Leishmania braziliensis	33%	100%
A4H9X2	Leishmania braziliensis	32%	100%
A4H9X5	Leishmania braziliensis	25%	100%
A4HA94	Leishmania braziliensis	29%	100%
A4HAC8	Leishmania braziliensis	25%	100%
A4HBL4	Leishmania braziliensis	25%	100%
A4HBW8	Leishmania braziliensis	27%	99%
A4HCD7	Leishmania braziliensis	38%	69%
A4HCE6	Leishmania braziliensis	33%	100%
A4HED7	Leishmania braziliensis	33%	100%
A4HEL2	Leishmania braziliensis	26%	100%
A4HFI2	Leishmania braziliensis	27%	100%
A4HG26	Leishmania braziliensis	24%	100%
A4HG92	Leishmania braziliensis	33%	100%
A4HHS9	Leishmania braziliensis	26%	100%
A4HIM5	Leishmania braziliensis	25%	100%
A4HJT5	Leishmania braziliensis	30%	67%
A4HJW2	Leishmania braziliensis	32%	69%
A4HLJ9	Leishmania braziliensis	24%	100%
A4HLR0	Leishmania braziliensis	33%	66%
A4HN71	Leishmania braziliensis	35%	100%
A4HNG3	Leishmania braziliensis	32%	100%
A4HNR5	Leishmania braziliensis	29%	100%
A4HQG8	Leishmania braziliensis	25%	100%
A4HRN3	Leishmania infantum	25%	100%
A4HSE2	Leishmania infantum	26%	100%
A4HTB4	Leishmania infantum	98%	100%
A4HUC8	Leishmania infantum	28%	100%
A4HUG1	Leishmania infantum	26%	100%
A4HUS3	Leishmania infantum	25%	100%
A4HWP5	Leishmania infantum	33%	77%
A4HXU0	Leishmania infantum	66%	100%
A4HXY2	Leishmania infantum	33%	89%
A4HYH4	Leishmania infantum	30%	100%
A4HYX6	Leishmania infantum	25%	100%
A4HZA2	Leishmania infantum	26%	100%
A4HZV1	Leishmania infantum	38%	80%
A4HZW8	Leishmania infantum	34%	83%
A4I1T4	Leishmania infantum	33%	76%
A4I1U3	Leishmania infantum	26%	99%
A4I3C6	Leishmania infantum	33%	98%
A4I4Y0	Leishmania infantum	26%	100%
A4I7A1	Leishmania infantum	30%	67%
A4I7C4	Leishmania infantum	32%	69%
A4I910	Leishmania infantum	23%	100%
A4I960	Leishmania infantum	32%	66%
A4I9H1	Leishmania infantum	25%	100%
A4IBT4	Leishmania infantum	35%	77%
A4IBT9	Leishmania infantum	35%	80%
A4IC54	Leishmania infantum	33%	76%
A4ICT0	Leishmania infantum	29%	100%
A4IGM9	Xenopus tropicalis	36%	82%
A5GFW1	Sus scrofa	37%	74%
A8X6H4	Caenorhabditis briggsae	42%	83%
A8XJQ6	Caenorhabditis briggsae	32%	77%
A8XW88	Caenorhabditis briggsae	34%	79%
A9TF79	Physcomitrium patens	42%	85%
C9ZKE1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	73%
C9ZL78	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	70%
C9ZMH9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	67%
C9ZSI7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	97%
C9ZUK8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	100%
C9ZWI1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	69%
C9ZWK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	67%
C9ZXP1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	76%
C9ZYF0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	81%
C9ZYS7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	75%
C9ZYT4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	74%
C9ZZX0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	100%
C9ZZX1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	60%	100%
D0A2M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	95%
D0A5C6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	88%
D0A820	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	92%
D7UQM5	Patiria pectinifera	39%	73%
E9ACB1	Leishmania major	25%	100%
E9ACW6	Leishmania major	25%	100%
E9AD33	Leishmania major	26%	100%
E9AED4	Leishmania major	27%	100%
E9AFM1	Leishmania major	35%	100%
E9AFX4	Leishmania major	33%	100%
E9AGR7	Leishmania infantum	31%	100%
E9AGS0	Leishmania infantum	25%	100%
E9AGX6	Leishmania infantum	26%	99%
E9AJJ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AKB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ALF2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AN28	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AN59	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9ANF7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AQF3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9ARK2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	65%	100%
E9ARP5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	89%
E9ARW6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9ARW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AS98	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ASH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AUS3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AUY2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AV92	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	99%
E9AVR5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	80%
E9AVS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AXW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	76%
E9AXY7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	99%
E9AZF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AZL3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9B296	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	67%
E9B2B7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	69%
E9B3X5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9B436	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	66%
E9B4G9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9B6S4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	77%
E9B6S9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	80%
E9B727	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	76%
O01427	Caenorhabditis elegans	40%	97%
O08875	Rattus norvegicus	39%	68%
O14965	Homo sapiens	36%	73%
O22932	Arabidopsis thaliana	51%	68%
O54784	Mus musculus	35%	66%
O54863	Mus musculus	36%	83%
O55099	Rattus norvegicus	35%	86%
O59697	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	70%
O59790	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	83%
O64629	Arabidopsis thaliana	35%	100%
O64812	Arabidopsis thaliana	42%	87%
O65554	Arabidopsis thaliana	53%	67%
O70126	Mus musculus	35%	86%
O70150	Rattus norvegicus	40%	86%
O80902	Arabidopsis thaliana	50%	69%
O88445	Mus musculus	36%	100%
O88764	Rattus norvegicus	35%	66%
O96526	Leishmania major	29%	100%
P00517	Bos taurus	36%	84%
P05131	Bos taurus	35%	84%
P05132	Mus musculus	35%	84%
P05383	Sus scrofa	35%	84%
P05986	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	74%
P06244	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	75%
P06245	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	78%
P0C5D6	Oryza sativa subsp. japonica	40%	89%
P11801	Homo sapiens	37%	70%
P12370	Drosophila melanogaster	35%	84%
P16911	Drosophila melanogaster	34%	84%
P17612	Homo sapiens	36%	84%
P21137	Caenorhabditis elegans	33%	73%
P22612	Homo sapiens	33%	84%
P22694	Homo sapiens	35%	84%
P25321	Cricetulus griseus	35%	84%
P25323	Dictyostelium discoideum	37%	100%
P27791	Rattus norvegicus	35%	84%
P36887	Sus scrofa	36%	84%
P38991	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	81%
P43291	Arabidopsis thaliana	41%	82%
P43292	Arabidopsis thaliana	40%	84%
P49673	Ascaris suum	31%	88%
P51817	Homo sapiens	35%	83%
P54644	Dictyostelium discoideum	35%	67%
P59241	Rattus norvegicus	37%	75%
P68180	Cricetulus griseus	35%	84%
P68181	Mus musculus	35%	84%
P68182	Rattus norvegicus	35%	84%
P92937	Arabidopsis thaliana	52%	70%
P97477	Mus musculus	35%	75%
Q02066	Triticum aestivum	42%	89%
Q09136	Sus scrofa	40%	77%
Q0D4J7	Oryza sativa subsp. japonica	43%	87%
Q0V7M1	Bos taurus	37%	70%
Q14012	Homo sapiens	40%	80%
Q27687	Leishmania major	33%	100%
Q2QY53	Oryza sativa subsp. japonica	54%	68%
Q2QYM3	Oryza sativa subsp. japonica	51%	67%
Q2RBF0	Oryza sativa subsp. japonica	51%	68%
Q2TA06	Bos taurus	36%	74%
Q2V452	Arabidopsis thaliana	51%	67%
Q39192	Arabidopsis thaliana	41%	82%
Q39193	Arabidopsis thaliana	39%	82%
Q3SZW1	Bos taurus	40%	81%
Q4KTY1	Pinctada fucata	37%	71%
Q4Q3K6	Leishmania major	25%	100%
Q4Q3Y9	Leishmania major	32%	66%
Q4Q449	Leishmania major	23%	100%
Q4Q5T9	Leishmania major	32%	69%
Q4Q5W2	Leishmania major	30%	67%
Q4Q9I7	Leishmania major	25%	99%
Q4Q9K2	Leishmania major	33%	100%
Q4QBQ2	Leishmania major	34%	100%
Q4QBR6	Leishmania major	38%	100%
Q4QC88	Leishmania major	26%	99%
Q4QCK0	Leishmania major	24%	100%
Q4QCR2	Leishmania major	25%	100%
Q4QCR3	Leishmania major	24%	100%
Q4QD66	Leishmania major	30%	100%
Q4QDK3	Leishmania major	25%	100%
Q4QDK6	Leishmania major	31%	100%
Q4QDX7	Leishmania major	66%	100%
Q4QF23	Leishmania major	33%	100%
Q4QH69	Leishmania major	25%	100%
Q4QHG6	Leishmania major	26%	100%
Q4QHJ8	Leishmania major	28%	100%
Q4QIJ7	Leishmania major	98%	100%
Q4QJJ0	Leishmania major	26%	100%
Q501V0	Danio rerio	37%	70%
Q54CY9	Dictyostelium discoideum	39%	95%
Q54SJ5	Dictyostelium discoideum	40%	95%
Q54WX4	Dictyostelium discoideum	38%	77%
Q5JLD8	Oryza sativa subsp. japonica	48%	66%
Q5N942	Oryza sativa subsp. japonica	43%	82%
Q61241	Mus musculus	39%	81%
Q61XD3	Caenorhabditis briggsae	39%	98%
Q63450	Rattus norvegicus	40%	79%
Q683C9	Arabidopsis thaliana	34%	100%
Q6A1A2	Homo sapiens	33%	75%
Q6BVA0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	34%	72%
Q6C3J2	Yarrowia lipolytica (strain CLIB 122 / E 150)	39%	80%
Q6CWQ4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	33%	82%
Q6DE08	Xenopus laevis	36%	82%
Q6ERS0	Oryza sativa subsp. japonica	52%	73%
Q6FV07	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	33%	83%
Q6GPL3	Xenopus laevis	36%	80%
Q6NW76	Danio rerio	36%	92%
Q6P2M8	Homo sapiens	40%	86%
Q6SA08	Homo sapiens	35%	90%
Q6ZI44	Oryza sativa subsp. japonica	43%	81%
Q755C4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	33%	81%
Q75GK4	Oryza sativa subsp. japonica	48%	66%
Q75H77	Oryza sativa subsp. japonica	42%	82%
Q75LR7	Oryza sativa subsp. japonica	44%	87%
Q75V57	Oryza sativa subsp. japonica	44%	82%
Q7JP68	Caenorhabditis elegans	33%	74%
Q7X996	Oryza sativa subsp. japonica	54%	67%
Q7XIW5	Oryza sativa subsp. japonica	43%	67%
Q7XKA8	Oryza sativa subsp. japonica	44%	80%
Q7XQP4	Oryza sativa subsp. japonica	42%	82%
Q7Y0B9	Oryza sativa subsp. japonica	42%	80%
Q7YRC6	Bos taurus	35%	86%
Q84VQ3	Arabidopsis thaliana	50%	67%
Q869W6	Dictyostelium discoideum	40%	85%
Q86AD7	Dictyostelium discoideum	37%	76%
Q8BHI9	Mus musculus	37%	68%
Q8BW96	Mus musculus	39%	77%
Q8IU85	Homo sapiens	39%	77%
Q8IY84	Homo sapiens	38%	68%
Q8LIG4	Oryza sativa subsp. japonica	52%	67%
Q8MJ44	Canis lupus familiaris	36%	85%
Q8RWC9	Arabidopsis thaliana	51%	67%
Q8VDF3	Mus musculus	35%	80%
Q8WQ45	Leishmania donovani	29%	100%
Q91819	Xenopus laevis	37%	73%
Q91820	Xenopus laevis	38%	73%
Q91YA2	Mus musculus	37%	70%
Q91YS8	Mus musculus	40%	79%
Q922R0	Mus musculus	33%	83%
Q940H6	Arabidopsis thaliana	43%	82%
Q94C40	Arabidopsis thaliana	47%	69%
Q94CG0	Arabidopsis thaliana	43%	71%
Q96GD4	Homo sapiens	36%	86%
Q96PF2	Homo sapiens	36%	83%
Q96PN8	Homo sapiens	39%	100%
Q96QS6	Homo sapiens	36%	77%
Q9BXA7	Homo sapiens	40%	81%
Q9C958	Arabidopsis thaliana	42%	82%
Q9D2E1	Mus musculus	39%	100%
Q9D411	Mus musculus	35%	90%
Q9FFP9	Arabidopsis thaliana	42%	82%
Q9FJ54	Arabidopsis thaliana	49%	67%
Q9GNR4	Leishmania major	35%	100%
Q9LDI3	Arabidopsis thaliana	50%	66%
Q9LEU7	Arabidopsis thaliana	55%	67%
Q9LZW4	Arabidopsis thaliana	51%	67%
Q9M077	Arabidopsis thaliana	34%	100%
Q9M9E9	Arabidopsis thaliana	40%	86%
Q9MAM1	Arabidopsis thaliana	54%	66%
Q9MZD9	Ovis aries	36%	84%
Q9N0X0	Sus scrofa	36%	86%
Q9N2N1	Leishmania major	33%	100%
Q9P7I2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	88%
Q9QYK9	Mus musculus	40%	86%
Q9SMQ4	Arabidopsis thaliana	42%	85%
Q9SPK4	Arabidopsis thaliana	36%	100%
Q9STV4	Arabidopsis thaliana	51%	67%
Q9SUL7	Arabidopsis thaliana	51%	69%
Q9TXJ0	Caenorhabditis elegans	41%	85%
Q9U6V4	Leishmania donovani	30%	100%
Q9UIK4	Homo sapiens	35%	80%
Q9UQB9	Homo sapiens	37%	96%
Q9VKN7	Drosophila melanogaster	36%	90%
Q9XIW0	Arabidopsis thaliana	49%	69%
Q9Y899	Emericella nidulans	37%	73%
V5B871	Trypanosoma cruzi	34%	69%
V5BAZ8	Trypanosoma cruzi	34%	77%
V5BC61	Trypanosoma cruzi	31%	95%
V5BCH2	Trypanosoma cruzi	30%	76%
V5BEK5	Trypanosoma cruzi	36%	88%
V5BFK9	Trypanosoma cruzi	28%	100%
V5BG98	Trypanosoma cruzi	32%	96%
V5BNV8	Trypanosoma cruzi	78%	100%
V5BPE2	Trypanosoma cruzi	32%	81%
V5BQH6	Trypanosoma cruzi	29%	68%
V5BR65	Trypanosoma cruzi	29%	74%
V5BV49	Trypanosoma cruzi	29%	95%
V5BWC2	Trypanosoma cruzi	62%	100%
V5D579	Trypanosoma cruzi	30%	69%
V5DI55	Trypanosoma cruzi	33%	71%
V5DMJ4	Trypanosoma cruzi	37%	87%
V5DPP5	Trypanosoma cruzi	27%	69%
W0LYS5	Macrobrachium nipponense	41%	86%