UBA domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AL94_LEIMU

TriTrypDb:

LmxM.07.0790

Length:

287

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AL94

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AL94

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	104	106	PF00675	0.600
CLV_NRD_NRD_1	182	184	PF00675	0.627
CLV_NRD_NRD_1	270	272	PF00675	0.520
CLV_NRD_NRD_1	99	101	PF00675	0.632
CLV_PCSK_KEX2_1	106	108	PF00082	0.592
CLV_PCSK_KEX2_1	182	184	PF00082	0.627
CLV_PCSK_KEX2_1	270	272	PF00082	0.510
CLV_PCSK_KEX2_1	98	100	PF00082	0.635
CLV_PCSK_PC1ET2_1	106	108	PF00082	0.602
DEG_Nend_UBRbox_4	1	3	PF02207	0.629
DOC_CKS1_1	154	159	PF01111	0.689
DOC_MAPK_gen_1	233	242	PF00069	0.622
DOC_PP2B_LxvP_1	5	8	PF13499	0.670
DOC_PP2B_LxvP_1	65	68	PF13499	0.642
DOC_USP7_MATH_1	128	132	PF00917	0.601
DOC_USP7_MATH_1	220	224	PF00917	0.687
DOC_WW_Pin1_4	124	129	PF00397	0.638
DOC_WW_Pin1_4	153	158	PF00397	0.693
DOC_WW_Pin1_4	281	286	PF00397	0.665
DOC_WW_Pin1_4	66	71	PF00397	0.531
LIG_14-3-3_CanoR_1	165	170	PF00244	0.609
LIG_14-3-3_CanoR_1	235	242	PF00244	0.551
LIG_CaM_IQ_9	175	190	PF13499	0.574
LIG_EVH1_1	5	9	PF00568	0.682
LIG_FHA_1	134	140	PF00498	0.568
LIG_FHA_1	154	160	PF00498	0.683
LIG_FHA_1	176	182	PF00498	0.595
LIG_FHA_1	216	222	PF00498	0.646
LIG_FHA_1	40	46	PF00498	0.613
LIG_FHA_2	141	147	PF00498	0.661
LIG_FHA_2	197	203	PF00498	0.572
LIG_GBD_Chelix_1	249	257	PF00786	0.490
LIG_PCNA_yPIPBox_3	30	40	PF02747	0.504
LIG_SH2_SRC	275	278	PF00017	0.513
LIG_SH2_STAT5	275	278	PF00017	0.513
LIG_SH3_3	151	157	PF00018	0.741
LIG_SH3_3	3	9	PF00018	0.720
LIG_Sin3_3	135	142	PF02671	0.500
LIG_SUMO_SIM_anti_2	246	252	PF11976	0.580
MOD_CDK_SPxxK_3	66	73	PF00069	0.601
MOD_CK1_1	153	159	PF00069	0.679
MOD_CK1_1	161	167	PF00069	0.634
MOD_CK1_1	20	26	PF00069	0.549
MOD_CK1_1	206	212	PF00069	0.727
MOD_CK1_1	266	272	PF00069	0.581
MOD_CK2_1	140	146	PF00069	0.631
MOD_CK2_1	196	202	PF00069	0.650
MOD_CK2_1	210	216	PF00069	0.570
MOD_CK2_1	53	59	PF00069	0.480
MOD_GlcNHglycan	131	134	PF01048	0.745
MOD_GlcNHglycan	212	215	PF01048	0.692
MOD_GlcNHglycan	218	221	PF01048	0.626
MOD_GlcNHglycan	242	245	PF01048	0.518
MOD_GlcNHglycan	55	58	PF01048	0.430
MOD_GSK3_1	124	131	PF00069	0.723
MOD_GSK3_1	146	153	PF00069	0.567
MOD_GSK3_1	161	168	PF00069	0.656
MOD_GSK3_1	202	209	PF00069	0.634
MOD_GSK3_1	216	223	PF00069	0.557
MOD_GSK3_1	88	95	PF00069	0.523
MOD_N-GLC_1	15	20	PF02516	0.655
MOD_NEK2_1	240	245	PF00069	0.530
MOD_NEK2_1	39	44	PF00069	0.520
MOD_NEK2_1	53	58	PF00069	0.481
MOD_PIKK_1	175	181	PF00454	0.607
MOD_PKA_2	269	275	PF00069	0.581
MOD_Plk_1	263	269	PF00069	0.585
MOD_Plk_2-3	92	98	PF00069	0.516
MOD_Plk_4	150	156	PF00069	0.597
MOD_ProDKin_1	124	130	PF00069	0.775
MOD_ProDKin_1	153	159	PF00069	0.692
MOD_ProDKin_1	281	287	PF00069	0.675
MOD_ProDKin_1	66	72	PF00069	0.534
TRG_DiLeu_BaEn_1	252	257	PF01217	0.382
TRG_ER_diArg_1	104	107	PF00400	0.624
TRG_ER_diArg_1	181	183	PF00400	0.626
TRG_ER_diArg_1	270	273	PF00400	0.511
TRG_ER_diArg_1	98	100	PF00400	0.705
TRG_NLS_MonoExtN_4	104	109	PF00514	0.605
TRG_Pf-PMV_PEXEL_1	192	197	PF00026	0.571

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDZ9	Leptomonas seymouri	39%	94%
A0A3S7WPY2	Leishmania donovani	85%	99%
A4H531	Leishmania braziliensis	69%	99%
A4HTA5	Leishmania infantum	86%	88%
Q4QIL0	Leishmania major	86%	100%