Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AL85_LEIMU

TriTrypDb:

LmxM.07.0715

Length:

580

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AL85

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AL85

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	171	175	PF00656	0.554
CLV_C14_Caspase3-7	3	7	PF00656	0.617
CLV_C14_Caspase3-7	407	411	PF00656	0.517
CLV_NRD_NRD_1	13	15	PF00675	0.573
CLV_NRD_NRD_1	20	22	PF00675	0.552
CLV_NRD_NRD_1	369	371	PF00675	0.675
CLV_NRD_NRD_1	396	398	PF00675	0.568
CLV_NRD_NRD_1	428	430	PF00675	0.538
CLV_NRD_NRD_1	449	451	PF00675	0.590
CLV_NRD_NRD_1	566	568	PF00675	0.572
CLV_NRD_NRD_1	78	80	PF00675	0.548
CLV_PCSK_KEX2_1	13	15	PF00082	0.573
CLV_PCSK_KEX2_1	20	22	PF00082	0.552
CLV_PCSK_KEX2_1	369	371	PF00082	0.533
CLV_PCSK_KEX2_1	396	398	PF00082	0.565
CLV_PCSK_KEX2_1	428	430	PF00082	0.527
CLV_PCSK_KEX2_1	432	434	PF00082	0.529
CLV_PCSK_KEX2_1	449	451	PF00082	0.632
CLV_PCSK_KEX2_1	566	568	PF00082	0.572
CLV_PCSK_PC1ET2_1	432	434	PF00082	0.544
CLV_PCSK_PC7_1	428	434	PF00082	0.541
CLV_PCSK_PC7_1	9	15	PF00082	0.575
CLV_PCSK_SKI1_1	155	159	PF00082	0.517
CLV_PCSK_SKI1_1	266	270	PF00082	0.650
CLV_PCSK_SKI1_1	335	339	PF00082	0.706
CLV_PCSK_SKI1_1	359	363	PF00082	0.618
CLV_PCSK_SKI1_1	369	373	PF00082	0.427
CLV_PCSK_SKI1_1	58	62	PF00082	0.487
DEG_APCC_DBOX_1	126	134	PF00400	0.646
DEG_APCC_DBOX_1	154	162	PF00400	0.511
DEG_APCC_DBOX_1	368	376	PF00400	0.488
DEG_Nend_UBRbox_2	1	3	PF02207	0.655
DEG_SCF_FBW7_1	35	41	PF00400	0.673
DEG_SPOP_SBC_1	260	264	PF00917	0.530
DOC_CKS1_1	267	272	PF01111	0.525
DOC_CKS1_1	35	40	PF01111	0.673
DOC_CKS1_1	464	469	PF01111	0.550
DOC_CKS1_1	523	528	PF01111	0.582
DOC_MAPK_gen_1	369	377	PF00069	0.520
DOC_MAPK_gen_1	431	440	PF00069	0.554
DOC_MAPK_gen_1	566	572	PF00069	0.419
DOC_PP1_RVXF_1	18	25	PF00149	0.603
DOC_PP2B_LxvP_1	308	311	PF13499	0.704
DOC_PP2B_LxvP_1	416	419	PF13499	0.573
DOC_USP7_MATH_1	177	181	PF00917	0.697
DOC_USP7_MATH_1	185	189	PF00917	0.616
DOC_USP7_MATH_1	260	264	PF00917	0.664
DOC_USP7_MATH_1	268	272	PF00917	0.594
DOC_USP7_MATH_1	275	279	PF00917	0.620
DOC_USP7_MATH_1	346	350	PF00917	0.665
DOC_USP7_MATH_1	38	42	PF00917	0.703
DOC_USP7_MATH_1	417	421	PF00917	0.567
DOC_USP7_MATH_1	43	47	PF00917	0.677
DOC_USP7_MATH_1	78	82	PF00917	0.545
DOC_WW_Pin1_4	266	271	PF00397	0.719
DOC_WW_Pin1_4	34	39	PF00397	0.682
DOC_WW_Pin1_4	351	356	PF00397	0.618
DOC_WW_Pin1_4	459	464	PF00397	0.718
DOC_WW_Pin1_4	49	54	PF00397	0.583
DOC_WW_Pin1_4	522	527	PF00397	0.596
DOC_WW_Pin1_4	74	79	PF00397	0.660
LIG_14-3-3_CanoR_1	178	186	PF00244	0.637
LIG_14-3-3_CanoR_1	258	267	PF00244	0.578
LIG_14-3-3_CanoR_1	299	308	PF00244	0.645
LIG_14-3-3_CanoR_1	31	36	PF00244	0.544
LIG_14-3-3_CanoR_1	314	319	PF00244	0.606
LIG_14-3-3_CanoR_1	343	353	PF00244	0.604
LIG_14-3-3_CanoR_1	421	430	PF00244	0.467
LIG_14-3-3_CanoR_1	449	457	PF00244	0.717
LIG_APCC_ABBA_1	292	297	PF00400	0.561
LIG_APCC_ABBA_1	543	548	PF00400	0.634
LIG_APCC_ABBAyCdc20_2	335	341	PF00400	0.560
LIG_BIR_III_2	248	252	PF00653	0.562
LIG_CaM_IQ_9	12	28	PF13499	0.507
LIG_FHA_1	252	258	PF00498	0.592
LIG_FHA_1	303	309	PF00498	0.720
LIG_FHA_1	310	316	PF00498	0.620
LIG_FHA_1	393	399	PF00498	0.580
LIG_FHA_1	464	470	PF00498	0.658
LIG_FHA_1	486	492	PF00498	0.659
LIG_FHA_2	169	175	PF00498	0.537
LIG_FHA_2	327	333	PF00498	0.611
LIG_FHA_2	35	41	PF00498	0.618
LIG_FHA_2	405	411	PF00498	0.507
LIG_FHA_2	421	427	PF00498	0.458
LIG_FHA_2	517	523	PF00498	0.639
LIG_GSK3_LRP6_1	463	468	PF00069	0.548
LIG_LIR_Gen_1	156	161	PF02991	0.676
LIG_LIR_Gen_1	196	205	PF02991	0.554
LIG_LIR_Gen_1	336	346	PF02991	0.657
LIG_LIR_Nem_3	156	160	PF02991	0.682
LIG_LIR_Nem_3	196	201	PF02991	0.557
LIG_LIR_Nem_3	336	342	PF02991	0.649
LIG_PROFILIN_1	533	539	PF00235	0.521
LIG_SH2_SRC	339	342	PF00017	0.572
LIG_SH2_STAT5	546	549	PF00017	0.610
LIG_SH3_3	254	260	PF00018	0.704
LIG_SH3_3	264	270	PF00018	0.635
LIG_SH3_3	349	355	PF00018	0.656
LIG_SH3_3	42	48	PF00018	0.713
LIG_SH3_3	458	464	PF00018	0.691
LIG_SH3_3	501	507	PF00018	0.651
LIG_SH3_3	531	537	PF00018	0.651
LIG_SH3_3	72	78	PF00018	0.654
LIG_SH3_3	80	86	PF00018	0.607
LIG_SUMO_SIM_par_1	404	411	PF11976	0.445
LIG_SUMO_SIM_par_1	414	420	PF11976	0.538
MOD_CDC14_SPxK_1	77	80	PF00782	0.664
MOD_CDK_SPK_2	354	359	PF00069	0.573
MOD_CDK_SPK_2	74	79	PF00069	0.539
MOD_CDK_SPxK_1	74	80	PF00069	0.662
MOD_CK1_1	114	120	PF00069	0.544
MOD_CK1_1	168	174	PF00069	0.581
MOD_CK1_1	180	186	PF00069	0.632
MOD_CK1_1	225	231	PF00069	0.558
MOD_CK1_1	271	277	PF00069	0.721
MOD_CK1_1	302	308	PF00069	0.665
MOD_CK1_1	325	331	PF00069	0.621
MOD_CK1_1	34	40	PF00069	0.556
MOD_CK1_1	354	360	PF00069	0.517
MOD_CK1_1	386	392	PF00069	0.541
MOD_CK1_1	420	426	PF00069	0.591
MOD_CK1_1	451	457	PF00069	0.705
MOD_CK1_1	459	465	PF00069	0.665
MOD_CK1_1	485	491	PF00069	0.662
MOD_CK1_1	509	515	PF00069	0.682
MOD_CK1_1	518	524	PF00069	0.628
MOD_CK2_1	420	426	PF00069	0.563
MOD_DYRK1A_RPxSP_1	266	270	PF00069	0.697
MOD_GlcNHglycan	108	111	PF01048	0.473
MOD_GlcNHglycan	114	117	PF01048	0.566
MOD_GlcNHglycan	138	142	PF01048	0.622
MOD_GlcNHglycan	167	170	PF01048	0.640
MOD_GlcNHglycan	187	190	PF01048	0.503
MOD_GlcNHglycan	2	5	PF01048	0.588
MOD_GlcNHglycan	231	234	PF01048	0.638
MOD_GlcNHglycan	263	266	PF01048	0.634
MOD_GlcNHglycan	270	273	PF01048	0.646
MOD_GlcNHglycan	344	347	PF01048	0.745
MOD_GlcNHglycan	389	392	PF01048	0.711
MOD_GlcNHglycan	423	426	PF01048	0.474
MOD_GlcNHglycan	484	487	PF01048	0.708
MOD_GlcNHglycan	540	543	PF01048	0.662
MOD_GlcNHglycan	58	61	PF01048	0.655
MOD_GlcNHglycan	88	91	PF01048	0.657
MOD_GSK3_1	106	113	PF00069	0.580
MOD_GSK3_1	180	187	PF00069	0.587
MOD_GSK3_1	225	232	PF00069	0.679
MOD_GSK3_1	271	278	PF00069	0.724
MOD_GSK3_1	299	306	PF00069	0.699
MOD_GSK3_1	310	317	PF00069	0.576
MOD_GSK3_1	322	329	PF00069	0.540
MOD_GSK3_1	34	41	PF00069	0.692
MOD_GSK3_1	342	349	PF00069	0.556
MOD_GSK3_1	382	389	PF00069	0.675
MOD_GSK3_1	404	411	PF00069	0.563
MOD_GSK3_1	417	424	PF00069	0.444
MOD_GSK3_1	43	50	PF00069	0.625
MOD_GSK3_1	448	455	PF00069	0.797
MOD_GSK3_1	459	466	PF00069	0.639
MOD_GSK3_1	505	512	PF00069	0.675
MOD_GSK3_1	518	525	PF00069	0.589
MOD_GSK3_1	74	81	PF00069	0.617
MOD_N-GLC_1	441	446	PF02516	0.483
MOD_NEK2_1	112	117	PF00069	0.493
MOD_NEK2_1	211	216	PF00069	0.579
MOD_NEK2_1	223	228	PF00069	0.546
MOD_NEK2_1	362	367	PF00069	0.593
MOD_NEK2_1	408	413	PF00069	0.528
MOD_NEK2_1	448	453	PF00069	0.686
MOD_NEK2_2	53	58	PF00069	0.503
MOD_PIKK_1	303	309	PF00454	0.575
MOD_PIKK_1	441	447	PF00454	0.501
MOD_PIKK_1	546	552	PF00454	0.552
MOD_PKA_1	449	455	PF00069	0.668
MOD_PKA_2	165	171	PF00069	0.656
MOD_PKA_2	177	183	PF00069	0.610
MOD_PKA_2	303	309	PF00069	0.699
MOD_PKA_2	342	348	PF00069	0.619
MOD_PKA_2	420	426	PF00069	0.684
MOD_PKA_2	448	454	PF00069	0.693
MOD_PKA_2	78	84	PF00069	0.565
MOD_Plk_1	509	515	PF00069	0.636
MOD_Plk_4	276	282	PF00069	0.639
MOD_Plk_4	314	320	PF00069	0.667
MOD_Plk_4	78	84	PF00069	0.547
MOD_ProDKin_1	266	272	PF00069	0.716
MOD_ProDKin_1	34	40	PF00069	0.683
MOD_ProDKin_1	351	357	PF00069	0.613
MOD_ProDKin_1	459	465	PF00069	0.716
MOD_ProDKin_1	49	55	PF00069	0.579
MOD_ProDKin_1	522	528	PF00069	0.599
MOD_ProDKin_1	74	80	PF00069	0.662
TRG_DiLeu_BaEn_2	152	158	PF01217	0.619
TRG_ENDOCYTIC_2	339	342	PF00928	0.572
TRG_ER_diArg_1	12	14	PF00400	0.572
TRG_ER_diArg_1	19	21	PF00400	0.537
TRG_ER_diArg_1	369	371	PF00400	0.496
TRG_ER_diArg_1	396	398	PF00400	0.565
TRG_ER_diArg_1	427	429	PF00400	0.534
TRG_ER_diArg_1	430	433	PF00400	0.526
TRG_ER_diArg_1	448	450	PF00400	0.489
TRG_ER_diArg_1	566	568	PF00400	0.537
TRG_NLS_MonoExtN_4	428	435	PF00514	0.541
TRG_Pf-PMV_PEXEL_1	566	571	PF00026	0.574

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WPX7	Leishmania donovani	81%	100%
A4H523	Leishmania braziliensis	56%	100%
A4HT96	Leishmania infantum	81%	100%
E9ACQ2	Leishmania major	80%	100%