LeishMANIAdb
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Vesicle transport protein USE1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Vesicle transport protein USE1
Gene product:
Qa-SNARE protein, putative
Species:
Leishmania mexicana
UniProt:
E9AL80_LEIMU
TriTrypDb:
LmxM.07.0670
Length:
169

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
Term Name Level Count
GO:0016020 membrane 2 7
GO:0110165 cellular anatomical entity 1 7

Expansion

Sequence features

E9AL80
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AL80

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 117 121 PF00656 0.474
CLV_NRD_NRD_1 167 169 PF00675 0.604
DEG_Nend_UBRbox_1 1 4 PF02207 0.697
DEG_SIAH_1 57 65 PF03145 0.663
DEG_SPOP_SBC_1 69 73 PF00917 0.680
DOC_CKS1_1 27 32 PF01111 0.594
DOC_USP7_MATH_1 64 68 PF00917 0.716
DOC_USP7_UBL2_3 165 169 PF12436 0.383
DOC_WW_Pin1_4 26 31 PF00397 0.591
LIG_14-3-3_CanoR_1 41 47 PF00244 0.687
LIG_APCC_ABBA_1 138 143 PF00400 0.579
LIG_APCC_ABBAyCdc20_2 137 143 PF00400 0.582
LIG_EH1_1 152 160 PF00400 0.319
LIG_FHA_2 14 20 PF00498 0.662
LIG_LIR_Gen_1 97 105 PF02991 0.457
LIG_LIR_Nem_3 49 54 PF02991 0.715
LIG_LIR_Nem_3 97 102 PF02991 0.482
LIG_SH2_CRK 51 55 PF00017 0.704
LIG_SH2_CRK 99 103 PF00017 0.479
LIG_SH2_STAP1 163 167 PF00017 0.422
LIG_SH3_3 24 30 PF00018 0.622
LIG_SUMO_SIM_par_1 158 164 PF11976 0.373
LIG_UBA3_1 157 165 PF00899 0.388
LIG_UBA3_1 17 22 PF00899 0.702
MOD_CK1_1 115 121 PF00069 0.534
MOD_CK1_1 49 55 PF00069 0.729
MOD_CK1_1 71 77 PF00069 0.609
MOD_CK2_1 13 19 PF00069 0.662
MOD_GlcNHglycan 48 51 PF01048 0.485
MOD_GlcNHglycan 55 58 PF01048 0.462
MOD_GlcNHglycan 96 99 PF01048 0.321
MOD_GSK3_1 115 122 PF00069 0.544
MOD_GSK3_1 21 28 PF00069 0.730
MOD_GSK3_1 49 56 PF00069 0.705
MOD_GSK3_1 64 71 PF00069 0.689
MOD_GSK3_1 73 80 PF00069 0.617
MOD_GSK3_1 94 101 PF00069 0.506
MOD_N-GLC_1 65 70 PF02516 0.358
MOD_N-GLC_1 94 99 PF02516 0.270
MOD_NEK2_1 126 131 PF00069 0.532
MOD_NEK2_1 21 26 PF00069 0.721
MOD_PKA_2 40 46 PF00069 0.689
MOD_Plk_1 12 18 PF00069 0.659
MOD_Plk_1 65 71 PF00069 0.557
MOD_Plk_2-3 13 19 PF00069 0.566
MOD_Plk_4 13 19 PF00069 0.735
MOD_Plk_4 65 71 PF00069 0.637
MOD_ProDKin_1 26 32 PF00069 0.593
TRG_ENDOCYTIC_2 163 166 PF00928 0.356
TRG_ENDOCYTIC_2 51 54 PF00928 0.716
TRG_ENDOCYTIC_2 99 102 PF00928 0.454

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P2Y0 Leptomonas seymouri 70% 100%
A0A3R7K1F7 Trypanosoma rangeli 47% 100%
A0A3S5H5Z1 Leishmania donovani 86% 100%
A4H518 Leishmania braziliensis 76% 98%
A4HT91 Leishmania infantum 86% 100%
C9ZUN1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 42% 100%
Q4QIM4 Leishmania major 86% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS