LeishMANIAdb
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Calcium-transporting ATPase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Calcium-transporting ATPase
Gene product:
vacuolar-type Ca2+-ATPase, putative
Species:
Leishmania mexicana
UniProt:
E9AL76_LEIMU
TriTrypDb:
LmxM.07.0630
Length:
1104

Annotations

LeishMANIAdb annotations

Homologous to other eukaryotic P-type Ca2+ ATPases.. For some reason, this group has heavily expanded in Kinetoplastida.. Localization: Endosomal (by homology) / ER (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 20
NetGPI no yes: 0, no: 20
Cellular components
Term Name Level Count
GO:0016020 membrane 2 21
GO:0110165 cellular anatomical entity 1 21
GO:0005886 plasma membrane 3 3
GO:0043226 organelle 2 3
GO:0043227 membrane-bounded organelle 3 3
GO:0043229 intracellular organelle 3 3
GO:0043231 intracellular membrane-bounded organelle 4 3

Expansion

Sequence features

E9AL76
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AL76

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 21
GO:0003824 catalytic activity 1 21
GO:0005215 transporter activity 1 16
GO:0005388 P-type calcium transporter activity 4 16
GO:0005488 binding 1 21
GO:0005524 ATP binding 5 21
GO:0008324 monoatomic cation transmembrane transporter activity 4 16
GO:0015075 monoatomic ion transmembrane transporter activity 3 16
GO:0015085 calcium ion transmembrane transporter activity 6 16
GO:0015318 inorganic molecular entity transmembrane transporter activity 3 16
GO:0015399 primary active transmembrane transporter activity 4 16
GO:0015662 P-type ion transporter activity 4 16
GO:0016462 pyrophosphatase activity 5 21
GO:0016787 hydrolase activity 2 21
GO:0016817 hydrolase activity, acting on acid anhydrides 3 21
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 21
GO:0016887 ATP hydrolysis activity 7 21
GO:0017076 purine nucleotide binding 4 21
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 21
GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3 16
GO:0022804 active transmembrane transporter activity 3 16
GO:0022853 active monoatomic ion transmembrane transporter activity 4 16
GO:0022857 transmembrane transporter activity 2 16
GO:0022890 inorganic cation transmembrane transporter activity 4 16
GO:0030554 adenyl nucleotide binding 5 21
GO:0032553 ribonucleotide binding 3 21
GO:0032555 purine ribonucleotide binding 4 21
GO:0032559 adenyl ribonucleotide binding 5 21
GO:0035639 purine ribonucleoside triphosphate binding 4 21
GO:0036094 small molecule binding 2 21
GO:0042626 ATPase-coupled transmembrane transporter activity 2 16
GO:0043167 ion binding 2 21
GO:0043168 anion binding 3 21
GO:0046873 metal ion transmembrane transporter activity 5 16
GO:0097159 organic cyclic compound binding 2 21
GO:0097367 carbohydrate derivative binding 2 21
GO:0140358 P-type transmembrane transporter activity 3 16
GO:0140657 ATP-dependent activity 1 16
GO:1901265 nucleoside phosphate binding 3 21
GO:1901363 heterocyclic compound binding 2 21

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 639 643 PF00656 0.560
CLV_NRD_NRD_1 1076 1078 PF00675 0.414
CLV_NRD_NRD_1 179 181 PF00675 0.367
CLV_NRD_NRD_1 196 198 PF00675 0.359
CLV_NRD_NRD_1 249 251 PF00675 0.261
CLV_NRD_NRD_1 389 391 PF00675 0.386
CLV_NRD_NRD_1 537 539 PF00675 0.280
CLV_NRD_NRD_1 797 799 PF00675 0.291
CLV_NRD_NRD_1 860 862 PF00675 0.288
CLV_NRD_NRD_1 865 867 PF00675 0.284
CLV_NRD_NRD_1 873 875 PF00675 0.284
CLV_NRD_NRD_1 92 94 PF00675 0.257
CLV_NRD_NRD_1 929 931 PF00675 0.267
CLV_PCSK_FUR_1 194 198 PF00082 0.276
CLV_PCSK_KEX2_1 1050 1052 PF00082 0.427
CLV_PCSK_KEX2_1 1076 1078 PF00082 0.412
CLV_PCSK_KEX2_1 179 181 PF00082 0.497
CLV_PCSK_KEX2_1 196 198 PF00082 0.337
CLV_PCSK_KEX2_1 249 251 PF00082 0.261
CLV_PCSK_KEX2_1 389 391 PF00082 0.386
CLV_PCSK_KEX2_1 431 433 PF00082 0.495
CLV_PCSK_KEX2_1 539 541 PF00082 0.295
CLV_PCSK_KEX2_1 860 862 PF00082 0.327
CLV_PCSK_KEX2_1 873 875 PF00082 0.269
CLV_PCSK_KEX2_1 92 94 PF00082 0.268
CLV_PCSK_PC1ET2_1 1050 1052 PF00082 0.436
CLV_PCSK_PC1ET2_1 249 251 PF00082 0.261
CLV_PCSK_PC1ET2_1 431 433 PF00082 0.430
CLV_PCSK_PC1ET2_1 539 541 PF00082 0.297
CLV_PCSK_SKI1_1 1021 1025 PF00082 0.412
CLV_PCSK_SKI1_1 1026 1030 PF00082 0.400
CLV_PCSK_SKI1_1 1082 1086 PF00082 0.503
CLV_PCSK_SKI1_1 123 127 PF00082 0.336
CLV_PCSK_SKI1_1 200 204 PF00082 0.342
CLV_PCSK_SKI1_1 345 349 PF00082 0.245
CLV_PCSK_SKI1_1 527 531 PF00082 0.338
CLV_PCSK_SKI1_1 702 706 PF00082 0.344
CLV_PCSK_SKI1_1 724 728 PF00082 0.291
CLV_PCSK_SKI1_1 798 802 PF00082 0.276
CLV_PCSK_SKI1_1 92 96 PF00082 0.282
CLV_PCSK_SKI1_1 98 102 PF00082 0.265
DEG_APCC_DBOX_1 1020 1028 PF00400 0.466
DEG_MDM2_SWIB_1 896 903 PF02201 0.319
DEG_SCF_FBW7_2 296 303 PF00400 0.483
DEG_SPOP_SBC_1 466 470 PF00917 0.588
DOC_CYCLIN_RxL_1 796 806 PF00134 0.493
DOC_CYCLIN_yCln2_LP_2 436 442 PF00134 0.596
DOC_MAPK_DCC_7 432 442 PF00069 0.600
DOC_MAPK_gen_1 1048 1057 PF00069 0.520
DOC_MAPK_gen_1 194 204 PF00069 0.545
DOC_MAPK_gen_1 451 459 PF00069 0.426
DOC_MAPK_gen_1 798 805 PF00069 0.488
DOC_MAPK_gen_1 873 881 PF00069 0.519
DOC_MAPK_gen_1 905 915 PF00069 0.329
DOC_MAPK_gen_1 930 938 PF00069 0.503
DOC_MAPK_gen_1 944 951 PF00069 0.406
DOC_MAPK_MEF2A_6 197 206 PF00069 0.517
DOC_MAPK_MEF2A_6 724 731 PF00069 0.496
DOC_MAPK_MEF2A_6 798 807 PF00069 0.470
DOC_MAPK_MEF2A_6 873 881 PF00069 0.418
DOC_MAPK_MEF2A_6 944 951 PF00069 0.428
DOC_MAPK_NFAT4_5 724 732 PF00069 0.497
DOC_MAPK_NFAT4_5 798 806 PF00069 0.470
DOC_PP1_RVXF_1 783 790 PF00149 0.488
DOC_PP1_RVXF_1 972 978 PF00149 0.205
DOC_PP2B_LxvP_1 137 140 PF13499 0.438
DOC_PP2B_LxvP_1 221 224 PF13499 0.467
DOC_PP2B_PxIxI_1 946 952 PF00149 0.206
DOC_PP4_FxxP_1 1099 1102 PF00568 0.527
DOC_USP7_MATH_1 1039 1043 PF00917 0.561
DOC_USP7_MATH_1 129 133 PF00917 0.323
DOC_USP7_MATH_1 340 344 PF00917 0.539
DOC_USP7_MATH_1 458 462 PF00917 0.598
DOC_USP7_MATH_1 533 537 PF00917 0.461
DOC_USP7_MATH_1 620 624 PF00917 0.580
DOC_USP7_MATH_1 767 771 PF00917 0.530
DOC_USP7_MATH_1 869 873 PF00917 0.494
DOC_WW_Pin1_4 1098 1103 PF00397 0.573
DOC_WW_Pin1_4 215 220 PF00397 0.519
DOC_WW_Pin1_4 296 301 PF00397 0.459
DOC_WW_Pin1_4 32 37 PF00397 0.618
DOC_WW_Pin1_4 824 829 PF00397 0.330
LIG_14-3-3_CanoR_1 1053 1058 PF00244 0.652
LIG_14-3-3_CanoR_1 123 128 PF00244 0.260
LIG_14-3-3_CanoR_1 250 258 PF00244 0.457
LIG_14-3-3_CanoR_1 974 984 PF00244 0.205
LIG_Actin_WH2_2 438 456 PF00022 0.444
LIG_Actin_WH2_2 65 83 PF00022 0.544
LIG_Actin_WH2_2 963 978 PF00022 0.479
LIG_AP2alpha_1 347 351 PF02296 0.483
LIG_APCC_ABBA_1 9 14 PF00400 0.558
LIG_BIR_II_1 1 5 PF00653 0.642
LIG_BIR_III_4 695 699 PF00653 0.612
LIG_BRCT_BRCA1_1 944 948 PF00533 0.484
LIG_BRCT_BRCA1_1 952 956 PF00533 0.347
LIG_Clathr_ClatBox_1 999 1003 PF01394 0.594
LIG_CNOT1_NIM_1 344 353 PF04054 0.424
LIG_EH1_1 885 893 PF00400 0.188
LIG_EVH1_2 105 109 PF00568 0.476
LIG_FHA_1 1066 1072 PF00498 0.634
LIG_FHA_1 1083 1089 PF00498 0.566
LIG_FHA_1 149 155 PF00498 0.275
LIG_FHA_1 201 207 PF00498 0.468
LIG_FHA_1 258 264 PF00498 0.485
LIG_FHA_1 354 360 PF00498 0.458
LIG_FHA_1 369 375 PF00498 0.500
LIG_FHA_1 406 412 PF00498 0.516
LIG_FHA_1 600 606 PF00498 0.538
LIG_FHA_1 619 625 PF00498 0.554
LIG_FHA_1 829 835 PF00498 0.287
LIG_FHA_1 876 882 PF00498 0.373
LIG_FHA_1 979 985 PF00498 0.314
LIG_FHA_1 988 994 PF00498 0.390
LIG_FHA_2 1032 1038 PF00498 0.649
LIG_FHA_2 106 112 PF00498 0.492
LIG_FHA_2 136 142 PF00498 0.459
LIG_FHA_2 264 270 PF00498 0.493
LIG_FHA_2 33 39 PF00498 0.636
LIG_FHA_2 468 474 PF00498 0.678
LIG_FHA_2 503 509 PF00498 0.482
LIG_FHA_2 683 689 PF00498 0.518
LIG_FHA_2 731 737 PF00498 0.590
LIG_FHA_2 963 969 PF00498 0.341
LIG_GBD_Chelix_1 72 80 PF00786 0.267
LIG_Integrin_RGD_1 679 681 PF01839 0.307
LIG_LIR_Apic_2 1098 1102 PF02991 0.523
LIG_LIR_Gen_1 155 165 PF02991 0.339
LIG_LIR_Gen_1 178 187 PF02991 0.688
LIG_LIR_Gen_1 623 632 PF02991 0.560
LIG_LIR_Gen_1 806 817 PF02991 0.353
LIG_LIR_Gen_1 912 923 PF02991 0.312
LIG_LIR_Gen_1 953 962 PF02991 0.359
LIG_LIR_Gen_1 968 977 PF02991 0.238
LIG_LIR_Gen_1 987 996 PF02991 0.321
LIG_LIR_LC3C_4 218 223 PF02991 0.492
LIG_LIR_Nem_3 1056 1062 PF02991 0.637
LIG_LIR_Nem_3 108 113 PF02991 0.459
LIG_LIR_Nem_3 155 160 PF02991 0.328
LIG_LIR_Nem_3 178 184 PF02991 0.600
LIG_LIR_Nem_3 343 347 PF02991 0.484
LIG_LIR_Nem_3 349 353 PF02991 0.483
LIG_LIR_Nem_3 623 629 PF02991 0.563
LIG_LIR_Nem_3 688 692 PF02991 0.524
LIG_LIR_Nem_3 777 783 PF02991 0.494
LIG_LIR_Nem_3 806 812 PF02991 0.353
LIG_LIR_Nem_3 912 918 PF02991 0.312
LIG_LIR_Nem_3 937 942 PF02991 0.505
LIG_LIR_Nem_3 945 951 PF02991 0.459
LIG_LIR_Nem_3 953 957 PF02991 0.322
LIG_LIR_Nem_3 965 969 PF02991 0.257
LIG_LIR_Nem_3 987 991 PF02991 0.347
LIG_NRBOX 322 328 PF00104 0.500
LIG_PCNA_TLS_4 345 352 PF02747 0.495
LIG_PCNA_yPIPBox_3 791 801 PF02747 0.472
LIG_PCNA_yPIPBox_3 905 918 PF02747 0.147
LIG_Pex14_1 1058 1062 PF04695 0.488
LIG_Pex14_1 153 157 PF04695 0.339
LIG_Pex14_2 1007 1011 PF04695 0.653
LIG_Pex14_2 347 351 PF04695 0.483
LIG_Pex14_2 896 900 PF04695 0.277
LIG_Pex14_2 920 924 PF04695 0.402
LIG_Pex14_2 938 942 PF04695 0.386
LIG_Pex14_2 954 958 PF04695 0.345
LIG_PTB_Apo_2 688 695 PF02174 0.568
LIG_PTB_Apo_2 752 759 PF02174 0.509
LIG_PTB_Phospho_1 688 694 PF10480 0.567
LIG_REV1ctd_RIR_1 93 101 PF16727 0.476
LIG_SH2_CRK 607 611 PF00017 0.619
LIG_SH2_CRK 885 889 PF00017 0.331
LIG_SH2_GRB2like 570 573 PF00017 0.547
LIG_SH2_NCK_1 933 937 PF00017 0.523
LIG_SH2_PTP2 809 812 PF00017 0.341
LIG_SH2_SRC 1062 1065 PF00017 0.478
LIG_SH2_SRC 933 936 PF00017 0.523
LIG_SH2_STAP1 1062 1066 PF00017 0.487
LIG_SH2_STAT5 229 232 PF00017 0.456
LIG_SH2_STAT5 350 353 PF00017 0.503
LIG_SH2_STAT5 422 425 PF00017 0.514
LIG_SH2_STAT5 570 573 PF00017 0.569
LIG_SH2_STAT5 809 812 PF00017 0.341
LIG_SH3_3 136 142 PF00018 0.443
LIG_SH3_3 357 363 PF00018 0.461
LIG_SH3_3 427 433 PF00018 0.585
LIG_SH3_3 632 638 PF00018 0.552
LIG_SH3_3 99 105 PF00018 0.476
LIG_SUMO_SIM_anti_2 162 168 PF11976 0.320
LIG_SUMO_SIM_anti_2 356 361 PF11976 0.427
LIG_SUMO_SIM_anti_2 772 778 PF11976 0.506
LIG_SUMO_SIM_anti_2 878 883 PF11976 0.413
LIG_SUMO_SIM_anti_2 981 987 PF11976 0.269
LIG_SUMO_SIM_par_1 162 168 PF11976 0.318
LIG_SUMO_SIM_par_1 201 208 PF11976 0.476
LIG_SUMO_SIM_par_1 255 260 PF11976 0.467
LIG_SUMO_SIM_par_1 325 331 PF11976 0.467
LIG_SUMO_SIM_par_1 358 364 PF11976 0.464
LIG_SUMO_SIM_par_1 366 371 PF11976 0.465
LIG_SUMO_SIM_par_1 727 733 PF11976 0.512
LIG_SUMO_SIM_par_1 736 741 PF11976 0.483
LIG_SUMO_SIM_par_1 772 778 PF11976 0.499
LIG_SUMO_SIM_par_1 959 965 PF11976 0.316
LIG_SUMO_SIM_par_1 981 987 PF11976 0.426
LIG_TRAF2_1 1001 1004 PF00917 0.598
LIG_TRAF2_1 300 303 PF00917 0.476
LIG_TRAF2_1 850 853 PF00917 0.366
LIG_TRAF2_1 854 857 PF00917 0.500
LIG_TYR_ITIM 348 353 PF00017 0.500
LIG_TYR_ITIM 605 610 PF00017 0.547
LIG_TYR_ITIM 807 812 PF00017 0.341
LIG_UBA3_1 923 931 PF00899 0.280
LIG_WRC_WIRS_1 951 956 PF05994 0.349
LIG_WRC_WIRS_1 963 968 PF05994 0.348
LIG_WRC_WIRS_1 985 990 PF05994 0.479
MOD_CDK_SPxxK_3 32 39 PF00069 0.515
MOD_CK1_1 1086 1092 PF00069 0.657
MOD_CK1_1 240 246 PF00069 0.472
MOD_CK1_1 405 411 PF00069 0.516
MOD_CK1_1 827 833 PF00069 0.274
MOD_CK1_1 978 984 PF00069 0.325
MOD_CK2_1 1031 1037 PF00069 0.661
MOD_CK2_1 105 111 PF00069 0.529
MOD_CK2_1 32 38 PF00069 0.670
MOD_CK2_1 325 331 PF00069 0.477
MOD_CK2_1 458 464 PF00069 0.555
MOD_CK2_1 467 473 PF00069 0.609
MOD_CK2_1 502 508 PF00069 0.567
MOD_CK2_1 730 736 PF00069 0.588
MOD_CK2_1 84 90 PF00069 0.455
MOD_GlcNHglycan 1041 1044 PF01048 0.444
MOD_GlcNHglycan 186 191 PF01048 0.443
MOD_GlcNHglycan 251 254 PF01048 0.283
MOD_GlcNHglycan 398 401 PF01048 0.341
MOD_GlcNHglycan 442 445 PF01048 0.424
MOD_GlcNHglycan 541 544 PF01048 0.286
MOD_GlcNHglycan 761 764 PF01048 0.362
MOD_GlcNHglycan 769 772 PF01048 0.337
MOD_GSK3_1 1082 1089 PF00069 0.683
MOD_GSK3_1 113 120 PF00069 0.522
MOD_GSK3_1 164 171 PF00069 0.314
MOD_GSK3_1 182 189 PF00069 0.603
MOD_GSK3_1 200 207 PF00069 0.486
MOD_GSK3_1 259 266 PF00069 0.456
MOD_GSK3_1 28 35 PF00069 0.728
MOD_GSK3_1 398 405 PF00069 0.504
MOD_GSK3_1 72 79 PF00069 0.559
MOD_GSK3_1 738 745 PF00069 0.512
MOD_GSK3_1 808 815 PF00069 0.327
MOD_GSK3_1 823 830 PF00069 0.296
MOD_GSK3_1 848 855 PF00069 0.313
MOD_GSK3_1 980 987 PF00069 0.436
MOD_LATS_1 555 561 PF00433 0.482
MOD_N-GLC_1 215 220 PF02516 0.366
MOD_N-GLC_1 459 464 PF02516 0.320
MOD_N-GLC_1 488 493 PF02516 0.241
MOD_N-GLC_1 599 604 PF02516 0.316
MOD_N-GLC_1 675 680 PF02516 0.301
MOD_NEK2_1 135 140 PF00069 0.435
MOD_NEK2_1 228 233 PF00069 0.552
MOD_NEK2_1 259 264 PF00069 0.443
MOD_NEK2_1 287 292 PF00069 0.483
MOD_NEK2_1 353 358 PF00069 0.419
MOD_NEK2_1 368 373 PF00069 0.476
MOD_NEK2_1 374 379 PF00069 0.455
MOD_NEK2_1 445 450 PF00069 0.601
MOD_NEK2_1 675 680 PF00069 0.609
MOD_NEK2_1 682 687 PF00069 0.561
MOD_NEK2_1 716 721 PF00069 0.517
MOD_NEK2_1 730 735 PF00069 0.494
MOD_NEK2_1 76 81 PF00069 0.525
MOD_NEK2_1 803 808 PF00069 0.322
MOD_NEK2_1 816 821 PF00069 0.322
MOD_NEK2_1 875 880 PF00069 0.461
MOD_NEK2_1 942 947 PF00069 0.488
MOD_NEK2_2 446 451 PF00069 0.595
MOD_NEK2_2 650 655 PF00069 0.507
MOD_PIKK_1 374 380 PF00454 0.466
MOD_PIKK_1 398 404 PF00454 0.512
MOD_PIKK_1 409 415 PF00454 0.542
MOD_PIKK_1 716 722 PF00454 0.530
MOD_PKA_1 249 255 PF00069 0.530
MOD_PKA_1 539 545 PF00069 0.470
MOD_PKA_2 249 255 PF00069 0.467
MOD_PKA_2 539 545 PF00069 0.483
MOD_PKA_2 904 910 PF00069 0.297
MOD_PKA_2 975 981 PF00069 0.205
MOD_PKB_1 1051 1059 PF00069 0.492
MOD_PKB_1 519 527 PF00069 0.431
MOD_Plk_1 117 123 PF00069 0.515
MOD_Plk_1 200 206 PF00069 0.492
MOD_Plk_1 237 243 PF00069 0.458
MOD_Plk_1 278 284 PF00069 0.477
MOD_Plk_1 599 605 PF00069 0.515
MOD_Plk_1 978 984 PF00069 0.182
MOD_Plk_2-3 852 858 PF00069 0.509
MOD_Plk_4 105 111 PF00069 0.460
MOD_Plk_4 1053 1059 PF00069 0.630
MOD_Plk_4 117 123 PF00069 0.457
MOD_Plk_4 129 135 PF00069 0.297
MOD_Plk_4 159 165 PF00069 0.323
MOD_Plk_4 231 237 PF00069 0.472
MOD_Plk_4 259 265 PF00069 0.468
MOD_Plk_4 325 331 PF00069 0.487
MOD_Plk_4 414 420 PF00069 0.514
MOD_Plk_4 548 554 PF00069 0.532
MOD_Plk_4 620 626 PF00069 0.597
MOD_Plk_4 711 717 PF00069 0.596
MOD_Plk_4 812 818 PF00069 0.319
MOD_Plk_4 909 915 PF00069 0.265
MOD_Plk_4 980 986 PF00069 0.333
MOD_ProDKin_1 1098 1104 PF00069 0.578
MOD_ProDKin_1 215 221 PF00069 0.519
MOD_ProDKin_1 296 302 PF00069 0.459
MOD_ProDKin_1 32 38 PF00069 0.611
MOD_ProDKin_1 824 830 PF00069 0.262
MOD_SUMO_rev_2 536 541 PF00179 0.466
TRG_DiLeu_BaEn_1 307 312 PF01217 0.518
TRG_DiLeu_BaEn_1 548 553 PF01217 0.482
TRG_DiLeu_BaLyEn_6 120 125 PF01217 0.436
TRG_DiLeu_BaLyEn_6 995 1000 PF01217 0.378
TRG_ENDOCYTIC_2 1093 1096 PF00928 0.583
TRG_ENDOCYTIC_2 344 347 PF00928 0.474
TRG_ENDOCYTIC_2 350 353 PF00928 0.465
TRG_ENDOCYTIC_2 422 425 PF00928 0.495
TRG_ENDOCYTIC_2 607 610 PF00928 0.526
TRG_ENDOCYTIC_2 63 66 PF00928 0.572
TRG_ENDOCYTIC_2 809 812 PF00928 0.460
TRG_ENDOCYTIC_2 885 888 PF00928 0.335
TRG_ENDOCYTIC_2 898 901 PF00928 0.291
TRG_ENDOCYTIC_2 933 936 PF00928 0.486
TRG_ER_diArg_1 1051 1054 PF00400 0.630
TRG_ER_diArg_1 1075 1077 PF00400 0.622
TRG_ER_diArg_1 179 181 PF00400 0.665
TRG_ER_diArg_1 193 196 PF00400 0.566
TRG_ER_diArg_1 388 390 PF00400 0.574
TRG_ER_diArg_1 538 541 PF00400 0.522
TRG_ER_diArg_1 585 588 PF00400 0.603
TRG_ER_diArg_1 859 861 PF00400 0.461
TRG_ER_diArg_1 873 875 PF00400 0.491
TRG_ER_diArg_1 974 977 PF00400 0.329
TRG_NES_CRM1_1 622 634 PF08389 0.556
TRG_NES_CRM1_1 720 736 PF08389 0.520
TRG_NLS_MonoExtN_4 1048 1054 PF00514 0.506
TRG_NLS_MonoExtN_4 248 253 PF00514 0.500
TRG_Pf-PMV_PEXEL_1 285 289 PF00026 0.283
TRG_Pf-PMV_PEXEL_1 451 455 PF00026 0.374
TRG_Pf-PMV_PEXEL_1 690 695 PF00026 0.328
TRG_Pf-PMV_PEXEL_1 930 934 PF00026 0.266

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3Y1 Leptomonas seymouri 29% 100%
A0A0N1HWG6 Leptomonas seymouri 41% 99%
A0A0N1PFH3 Leptomonas seymouri 26% 91%
A0A0S4J1M1 Bodo saltans 27% 100%
A0A0S4J5A1 Bodo saltans 27% 100%
A0A0S4J6U4 Bodo saltans 38% 100%
A0A0S4JA92 Bodo saltans 42% 100%
A0A0S4JDQ9 Bodo saltans 22% 99%
A0A0S4JRV4 Bodo saltans 40% 100%
A0A0S4KIG5 Bodo saltans 29% 100%
A0A0S4KNQ6 Bodo saltans 63% 99%
A0A1X0NNY6 Trypanosomatidae 29% 100%
A0A1X0NPD9 Trypanosomatidae 66% 100%
A0A1X0NTI6 Trypanosomatidae 41% 97%
A0A1X0P0Y8 Trypanosomatidae 36% 100%
A0A1X0P689 Trypanosomatidae 28% 100%
A0A1X0P720 Trypanosomatidae 24% 100%
A0A1X0P7A1 Trypanosomatidae 24% 100%
A0A1X0P842 Trypanosomatidae 23% 100%
A0A381MFJ0 Leishmania infantum 23% 100%
A0A3R7KM63 Trypanosoma rangeli 67% 100%
A0A3R7MRX8 Trypanosoma rangeli 27% 100%
A0A3S5H5Y9 Leishmania donovani 95% 100%
A0A3S5ISK9 Trypanosoma rangeli 35% 100%
A0A3S7WPW0 Leishmania donovani 86% 99%
A0A3S7WUG2 Leishmania donovani 40% 97%
A0A3S7WV61 Leishmania donovani 23% 100%
A0A3S7WV68 Leishmania donovani 23% 100%
A0A3S7X978 Leishmania donovani 27% 100%
A0A422NTS7 Trypanosoma rangeli 29% 100%
A0A451EJU6 Leishmania donovani 28% 100%
A2VDL6 Bos taurus 28% 100%
A4H3S2 Leishmania braziliensis 27% 100%
A4H514 Leishmania braziliensis 89% 100%
A4H903 Leishmania braziliensis 40% 100%
A4H9Q5 Leishmania braziliensis 24% 100%
A4HMM8 Leishmania braziliensis 27% 100%
A4HRZ6 Leishmania infantum 28% 100%
A4HT82 Leishmania infantum 85% 100%
A4HTF0 Leishmania infantum 95% 100%
A4HXD4 Leishmania infantum 40% 97%
A4HY23 Leishmania infantum 23% 100%
A4IBA6 Leishmania infantum 26% 100%
A7L9Z8 Mus musculus 28% 100%
C9ZPL1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZUN6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 60% 100%
C9ZZN4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
D0A4V8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
D0ZTB2 Salmonella typhimurium (strain 14028s / SGSC 2262) 24% 100%
D2WKD8 Sus scrofa 28% 100%
D3K0R6 Bos taurus 36% 91%
E9AF31 Leishmania major 27% 100%
E9AJY3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9AL78 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 99%
E9AR29 Leishmania mexicana (strain MHOM/GT/2001/U1103) 39% 97%
E9ART6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 100%
E9B686 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 90%
G5E829 Mus musculus 38% 90%
J9VQQ3 Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) 38% 78%
O14022 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 21% 100%
O14983 Homo sapiens 29% 100%
O22218 Arabidopsis thaliana 37% 100%
O23087 Arabidopsis thaliana 27% 100%
O34431 Bacillus subtilis (strain 168) 30% 100%
O43108 Yarrowia lipolytica (strain CLIB 122 / E 150) 28% 100%
O46674 Canis lupus familiaris 27% 100%
O55143 Mus musculus 28% 100%
O59868 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 100%
O64806 Arabidopsis thaliana 38% 100%
O74431 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 20% 84%
O75185 Homo sapiens 28% 100%
O77696 Sus scrofa 28% 100%
O81108 Arabidopsis thaliana 38% 100%
P04074 Ovis aries 26% 100%
P04191 Oryctolagus cuniculus 29% 100%
P05023 Homo sapiens 27% 100%
P05024 Sus scrofa 27% 100%
P05025 Tetronarce californica 28% 100%
P06685 Rattus norvegicus 27% 100%
P06686 Rattus norvegicus 28% 100%
P06687 Rattus norvegicus 27% 100%
P09572 Gallus gallus 28% 100%
P09626 Rattus norvegicus 25% 100%
P09627 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 24% 100%
P0ABB8 Escherichia coli (strain K12) 25% 100%
P0ABB9 Escherichia coli O157:H7 25% 100%
P11505 Rattus norvegicus 38% 90%
P11506 Rattus norvegicus 39% 89%
P11507 Rattus norvegicus 27% 100%
P11607 Sus scrofa 27% 100%
P11718 Leishmania donovani 23% 100%
P12522 Leishmania donovani 23% 100%
P13585 Gallus gallus 28% 100%
P13586 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 28% 100%
P13587 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 100%
P13607 Drosophila melanogaster 27% 100%
P13637 Homo sapiens 27% 100%
P16615 Homo sapiens 28% 100%
P17326 Artemia franciscana 28% 100%
P18596 Rattus norvegicus 28% 100%
P18907 Equus caballus 27% 100%
P19156 Sus scrofa 26% 100%
P20020 Homo sapiens 38% 90%
P20431 Arabidopsis thaliana 22% 100%
P20647 Oryctolagus cuniculus 27% 100%
P20648 Homo sapiens 25% 100%
P22036 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 24% 100%
P22189 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 27% 100%
P22700 Drosophila melanogaster 27% 100%
P23220 Sus scrofa 38% 90%
P23634 Homo sapiens 37% 89%
P24797 Gallus gallus 28% 100%
P24798 Gallus gallus 27% 100%
P25489 Catostomus commersonii 28% 100%
P27112 Oryctolagus cuniculus 25% 100%
P28774 Artemia franciscana 28% 100%
P30714 Rhinella marina 27% 100%
P35315 Trypanosoma brucei brucei 30% 100%
P35316 Artemia franciscana 25% 100%
P35317 Hydra vulgaris 28% 100%
P36640 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 24% 100%
P37278 Synechococcus elongatus (strain PCC 7942 / FACHB-805) 31% 100%
P37367 Synechocystis sp. (strain PCC 6803 / Kazusa) 28% 100%
P38929 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 94%
P47317 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) 27% 100%
P50993 Homo sapiens 28% 100%
P50996 Canis lupus familiaris 26% 100%
P50997 Canis lupus familiaris 27% 100%
P54209 Dunaliella bioculata 28% 100%
P54211 Dunaliella bioculata 23% 98%
P54678 Dictyostelium discoideum 40% 99%
P54679 Dictyostelium discoideum 23% 100%
P54707 Homo sapiens 28% 100%
P54708 Rattus norvegicus 27% 100%
P57709 Bos taurus 28% 100%
P58165 Oreochromis mossambicus 40% 99%
P58312 Oreochromis mossambicus 26% 100%
P63688 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 30% 100%
P70083 Makaira nigricans 27% 100%
P78036 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) 28% 100%
P92939 Arabidopsis thaliana 28% 100%
P98194 Homo sapiens 28% 100%
P9WPS8 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 30% 100%
P9WPS9 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 30% 100%
Q00779 Felis catus 27% 100%
Q00804 Oryctolagus cuniculus 38% 90%
Q01814 Homo sapiens 39% 89%
Q01896 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 100%
Q03669 Gallus gallus 27% 100%
Q07421 Ajellomyces capsulatus 24% 100%
Q08435 Nicotiana plumbaginifolia 23% 100%
Q08436 Nicotiana plumbaginifolia 22% 100%
Q08DA1 Bos taurus 26% 100%
Q0VCY0 Bos taurus 29% 100%
Q12691 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 100%
Q13733 Homo sapiens 29% 100%
Q16720 Homo sapiens 35% 90%
Q21286 Caenorhabditis elegans 22% 92%
Q292Q0 Drosophila pseudoobscura pseudoobscura 27% 100%
Q2QMX9 Oryza sativa subsp. japonica 37% 100%
Q2QY12 Oryza sativa subsp. japonica 37% 100%
Q2RAS0 Oryza sativa subsp. japonica 37% 100%
Q37145 Arabidopsis thaliana 37% 100%
Q42883 Solanum lycopersicum 27% 100%
Q43128 Arabidopsis thaliana 24% 100%
Q4QDN7 Leishmania major 23% 100%
Q4QDN8 Leishmania major 23% 100%
Q4QED4 Leishmania major 40% 100%
Q4QIM6 Leishmania major 85% 100%
Q4QIM8 Leishmania major 94% 100%
Q4VNC1 Homo sapiens 22% 92%
Q58623 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 25% 100%
Q5R5K5 Pongo abelii 28% 100%
Q5RCD8 Pongo abelii 28% 100%
Q5RDR3 Pongo abelii 27% 100%
Q5XF89 Mus musculus 20% 91%
Q5XF90 Mus musculus 21% 93%
Q5ZKB7 Gallus gallus 22% 92%
Q64392 Cavia porcellus 28% 100%
Q64436 Mus musculus 26% 100%
Q64518 Mus musculus 28% 100%
Q64541 Rattus norvegicus 26% 100%
Q64542 Rattus norvegicus 38% 92%
Q64566 Rattus norvegicus 27% 100%
Q64568 Rattus norvegicus 35% 88%
Q64578 Rattus norvegicus 28% 100%
Q65X71 Oryza sativa subsp. japonica 36% 100%
Q6ATV4 Oryza sativa subsp. japonica 38% 100%
Q6PIC6 Mus musculus 27% 100%
Q6PIE5 Mus musculus 28% 100%
Q6Q477 Mus musculus 36% 92%
Q6RWA9 Taenia solium 28% 100%
Q73E41 Bacillus cereus (strain ATCC 10987 / NRS 248) 29% 100%
Q7PPA5 Anopheles gambiae 28% 100%
Q7X8B5 Oryza sativa subsp. japonica 37% 100%
Q7XEK4 Oryza sativa subsp. japonica 36% 100%
Q80XR2 Mus musculus 27% 100%
Q8R429 Mus musculus 28% 100%
Q8R4C1 Rattus norvegicus 29% 100%
Q8RUN1 Oryza sativa subsp. japonica 37% 100%
Q8VDN2 Mus musculus 27% 100%
Q8Y8Q5 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 30% 100%
Q92030 Anguilla anguilla 28% 100%
Q92036 Rhinella marina 27% 100%
Q92105 Pelophylax lessonae 29% 100%
Q92123 Xenopus laevis 28% 100%
Q92126 Xenopus laevis 27% 100%
Q93084 Homo sapiens 28% 100%
Q95Z93 Leishmania major 28% 100%
Q98SH2 Gallus gallus 36% 92%
Q9CFU9 Lactococcus lactis subsp. lactis (strain IL1403) 28% 100%
Q9CTG6 Mus musculus 24% 94%
Q9HDW7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 39% 85%
Q9LF79 Arabidopsis thaliana 38% 100%
Q9LIK7 Arabidopsis thaliana 35% 100%
Q9LU41 Arabidopsis thaliana 36% 100%
Q9LV11 Arabidopsis thaliana 23% 100%
Q9LY77 Arabidopsis thaliana 36% 100%
Q9M2A0 Arabidopsis thaliana 22% 100%
Q9M2L4 Arabidopsis thaliana 38% 100%
Q9N0Z6 Oryctolagus cuniculus 27% 100%
Q9NQ11 Homo sapiens 23% 94%
Q9R0K7 Mus musculus 36% 92%
Q9SJB3 Arabidopsis thaliana 22% 100%
Q9SY55 Arabidopsis thaliana 27% 100%
Q9SZR1 Arabidopsis thaliana 37% 100%
Q9TV52 Oryctolagus cuniculus 29% 100%
Q9WV27 Mus musculus 27% 100%
Q9XES1 Arabidopsis thaliana 28% 100%
Q9Y2G3 Homo sapiens 21% 94%
Q9YGL9 Gallus gallus 28% 100%
Q9YH26 Oreochromis mossambicus 28% 100%
Q9Z1W8 Mus musculus 27% 100%
V5B873 Trypanosoma cruzi 65% 100%
V5BHZ2 Trypanosoma cruzi 26% 100%
V5BLM1 Trypanosoma cruzi 30% 100%
V5BPC6 Trypanosoma cruzi 35% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS