Transmembrane protein 188

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AL59_LEIMU

TriTrypDb:

LmxM.07.0475

Length:

159


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

E9AL59

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AL59


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	115	117	PF00082	0.367
CLV_PCSK_PC1ET2_1	115	117	PF00082	0.367
CLV_PCSK_SKI1_1	115	119	PF00082	0.408
CLV_PCSK_SKI1_1	12	16	PF00082	0.453
CLV_PCSK_SKI1_1	64	68	PF00082	0.608
CLV_PCSK_SKI1_1	95	99	PF00082	0.367
DOC_MAPK_DCC_7	75	83	PF00069	0.308
DOC_MAPK_gen_1	100	107	PF00069	0.633
DOC_MAPK_gen_1	9	17	PF00069	0.609
DOC_MAPK_MEF2A_6	100	107	PF00069	0.633
DOC_MAPK_MEF2A_6	75	83	PF00069	0.290
DOC_PP1_RVXF_1	35	41	PF00149	0.440
DOC_WW_Pin1_4	152	157	PF00397	0.699
LIG_14-3-3_CanoR_1	37	41	PF00244	0.449
LIG_Actin_WH2_2	125	142	PF00022	0.541
LIG_Actin_WH2_2	99	117	PF00022	0.542
LIG_FHA_1	153	159	PF00498	0.709
LIG_FHA_1	49	55	PF00498	0.401
LIG_LIR_Apic_2	70	76	PF02991	0.388
LIG_LIR_Gen_1	148	157	PF02991	0.698
LIG_LIR_Gen_1	39	48	PF02991	0.544
LIG_LIR_Nem_3	148	152	PF02991	0.605
LIG_LIR_Nem_3	39	43	PF02991	0.556
LIG_Pex14_1	40	44	PF04695	0.536
LIG_PTB_Apo_2	66	73	PF02174	0.404
LIG_PTB_Phospho_1	66	72	PF10480	0.406
LIG_SH2_CRK	73	77	PF00017	0.388
LIG_SH2_STAP1	110	114	PF00017	0.555
LIG_SH2_STAT5	13	16	PF00017	0.562
LIG_SH2_STAT5	42	45	PF00017	0.344
LIG_SH3_1	73	79	PF00018	0.387
LIG_SH3_3	73	79	PF00018	0.387
LIG_SUMO_SIM_par_1	13	18	PF11976	0.596
MOD_CDK_SPxxK_3	152	159	PF00069	0.714
MOD_NEK2_1	15	20	PF00069	0.629
MOD_NEK2_1	67	72	PF00069	0.408
MOD_PIKK_1	124	130	PF00454	0.610
MOD_PIKK_1	15	21	PF00454	0.606
MOD_PKA_2	36	42	PF00069	0.443
MOD_PKA_2	8	14	PF00069	0.541
MOD_Plk_1	15	21	PF00069	0.614
MOD_Plk_4	67	73	PF00069	0.410
MOD_ProDKin_1	152	158	PF00069	0.704
MOD_SUMO_rev_2	108	117	PF00179	0.551
TRG_ER_diArg_1	7	10	PF00400	0.623
TRG_ER_diArg_1	99	102	PF00400	0.548


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4IUG7	Bodo saltans	63%	95%
A0A1X0NPB3	Trypanosomatidae	70%	100%
A0A3S7WPV0	Leishmania donovani	97%	100%
A4H4Z7	Leishmania braziliensis	93%	100%
A4HT81	Leishmania infantum	97%	100%
C9ZUQ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	95%
Q4QIP5	Leishmania major	97%	100%
V5BYF1	Trypanosoma cruzi	71%	100%