LeishMANIAdb
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Succinate dehydrogenase assembly factor 4, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Succinate dehydrogenase assembly factor 4, mitochondrial
Gene product:
Protein of unknown function (DUF1674), putative
Species:
Leishmania mexicana
UniProt:
E9AL47_LEIMU
TriTrypDb:
LmxM.07.0360
Length:
107

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AL47
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AL47

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 3 5 PF00675 0.495
CLV_PCSK_KEX2_1 3 5 PF00082 0.495
CLV_PCSK_KEX2_1 52 54 PF00082 0.472
CLV_PCSK_PC1ET2_1 52 54 PF00082 0.572
CLV_PCSK_SKI1_1 52 56 PF00082 0.470
DEG_Nend_Nbox_1 1 3 PF02207 0.517
DOC_MAPK_gen_1 3 10 PF00069 0.454
DOC_MAPK_MEF2A_6 3 12 PF00069 0.488
LIG_14-3-3_CanoR_1 45 51 PF00244 0.494
LIG_14-3-3_CanoR_1 53 59 PF00244 0.401
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HZK6 Leptomonas seymouri 85% 100%
A0A0S4IQ64 Bodo saltans 69% 100%
A0A1X0NPS9 Trypanosomatidae 64% 100%
A0A3R7NGX7 Trypanosoma rangeli 66% 100%
A4H4Y2 Leishmania braziliensis 89% 100%
C9ZUR8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 58% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS