Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AL31_LEIMU

TriTrypDb:

LmxM.07.0210

Length:

252

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AL31

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AL31

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	26	30	PF00656	0.480
CLV_NRD_NRD_1	159	161	PF00675	0.576
CLV_NRD_NRD_1	23	25	PF00675	0.675
CLV_PCSK_KEX2_1	159	161	PF00082	0.576
CLV_PCSK_KEX2_1	23	25	PF00082	0.676
CLV_PCSK_SKI1_1	69	73	PF00082	0.444
CLV_Separin_Metazoa	183	187	PF03568	0.413
DEG_SCF_FBW7_1	84	91	PF00400	0.669
DOC_CKS1_1	85	90	PF01111	0.668
DOC_CYCLIN_RxL_1	66	75	PF00134	0.404
DOC_MAPK_MEF2A_6	137	145	PF00069	0.481
DOC_PP2B_LxvP_1	179	182	PF13499	0.473
DOC_PP2B_LxvP_1	185	188	PF13499	0.528
DOC_PP4_FxxP_1	213	216	PF00568	0.518
DOC_PP4_FxxP_1	4	7	PF00568	0.698
DOC_USP7_MATH_1	129	133	PF00917	0.608
DOC_USP7_MATH_1	239	243	PF00917	0.498
DOC_USP7_MATH_1	88	92	PF00917	0.654
DOC_WW_Pin1_4	10	15	PF00397	0.752
DOC_WW_Pin1_4	135	140	PF00397	0.538
DOC_WW_Pin1_4	198	203	PF00397	0.632
DOC_WW_Pin1_4	212	217	PF00397	0.701
DOC_WW_Pin1_4	72	77	PF00397	0.664
DOC_WW_Pin1_4	84	89	PF00397	0.692
LIG_14-3-3_CanoR_1	176	182	PF00244	0.527
LIG_14-3-3_CanoR_1	23	31	PF00244	0.618
LIG_14-3-3_CanoR_1	36	43	PF00244	0.477
LIG_APCC_ABBA_1	114	119	PF00400	0.529
LIG_BIR_III_4	19	23	PF00653	0.515
LIG_FHA_1	136	142	PF00498	0.558
LIG_FHA_2	11	17	PF00498	0.658
LIG_FHA_2	178	184	PF00498	0.441
LIG_FHA_2	36	42	PF00498	0.489
LIG_LIR_Apic_2	212	216	PF02991	0.564
LIG_LIR_Gen_1	112	122	PF02991	0.549
LIG_LIR_Gen_1	49	58	PF02991	0.523
LIG_LIR_Nem_3	112	118	PF02991	0.521
LIG_LIR_Nem_3	222	228	PF02991	0.635
LIG_LIR_Nem_3	49	54	PF02991	0.520
LIG_PDZ_Class_1	247	252	PF00595	0.583
LIG_Pex14_2	54	58	PF04695	0.528
LIG_SH2_NCK_1	161	165	PF00017	0.556
LIG_SH2_STAP1	161	165	PF00017	0.476
LIG_SH2_STAP1	240	244	PF00017	0.464
LIG_SH3_3	11	17	PF00018	0.688
LIG_SH3_3	70	76	PF00018	0.600
LIG_SH3_3	82	88	PF00018	0.667
LIG_SUMO_SIM_anti_2	108	115	PF11976	0.339
LIG_TRAF2_1	39	42	PF00917	0.480
MOD_CK1_1	215	221	PF00069	0.709
MOD_CK1_1	223	229	PF00069	0.589
MOD_CK1_1	75	81	PF00069	0.559
MOD_CK2_1	10	16	PF00069	0.627
MOD_CK2_1	129	135	PF00069	0.539
MOD_CK2_1	160	166	PF00069	0.486
MOD_CK2_1	177	183	PF00069	0.503
MOD_CK2_1	223	229	PF00069	0.553
MOD_CK2_1	35	41	PF00069	0.566
MOD_CK2_1	53	59	PF00069	0.525
MOD_CK2_1	88	94	PF00069	0.718
MOD_Cter_Amidation	21	24	PF01082	0.505
MOD_GlcNHglycan	162	165	PF01048	0.617
MOD_GlcNHglycan	207	210	PF01048	0.723
MOD_GlcNHglycan	222	225	PF01048	0.598
MOD_GlcNHglycan	77	80	PF01048	0.622
MOD_GlcNHglycan	99	102	PF01048	0.687
MOD_GSK3_1	105	112	PF00069	0.503
MOD_GSK3_1	198	205	PF00069	0.625
MOD_GSK3_1	211	218	PF00069	0.648
MOD_GSK3_1	219	226	PF00069	0.576
MOD_GSK3_1	49	56	PF00069	0.511
MOD_GSK3_1	71	78	PF00069	0.580
MOD_GSK3_1	84	91	PF00069	0.671
MOD_N-GLC_1	177	182	PF02516	0.515
MOD_NEK2_1	105	110	PF00069	0.474
MOD_NEK2_1	247	252	PF00069	0.580
MOD_NEK2_1	53	58	PF00069	0.503
MOD_PKA_1	23	29	PF00069	0.599
MOD_PKA_2	23	29	PF00069	0.652
MOD_PKA_2	35	41	PF00069	0.474
MOD_Plk_1	105	111	PF00069	0.483
MOD_Plk_1	177	183	PF00069	0.514
MOD_Plk_1	58	64	PF00069	0.509
MOD_Plk_4	106	112	PF00069	0.478
MOD_Plk_4	239	245	PF00069	0.475
MOD_ProDKin_1	10	16	PF00069	0.754
MOD_ProDKin_1	135	141	PF00069	0.529
MOD_ProDKin_1	198	204	PF00069	0.633
MOD_ProDKin_1	212	218	PF00069	0.697
MOD_ProDKin_1	72	78	PF00069	0.670
MOD_ProDKin_1	84	90	PF00069	0.692
MOD_SUMO_rev_2	132	139	PF00179	0.570
TRG_DiLeu_BaLyEn_6	136	141	PF01217	0.519
TRG_ENDOCYTIC_2	240	243	PF00928	0.472
TRG_ER_diArg_1	159	161	PF00400	0.579
TRG_ER_FFAT_2	208	219	PF00635	0.521

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I988	Leptomonas seymouri	36%	100%
A0A3S5H5W6	Leishmania donovani	86%	100%
A4H4W5	Leishmania braziliensis	61%	97%
A4HT39	Leishmania infantum	86%	100%
Q4QIS3	Leishmania major	81%	100%