CLASP_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AL14_LEIMU

TriTrypDb:

LmxM.07.0040

Length:

316

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AL14

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AL14

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	170	174	PF00656	0.626
CLV_C14_Caspase3-7	188	192	PF00656	0.684
CLV_NRD_NRD_1	226	228	PF00675	0.646
CLV_NRD_NRD_1	243	245	PF00675	0.510
CLV_NRD_NRD_1	301	303	PF00675	0.714
CLV_PCSK_FUR_1	299	303	PF00082	0.805
CLV_PCSK_KEX2_1	241	243	PF00082	0.743
CLV_PCSK_KEX2_1	298	300	PF00082	0.693
CLV_PCSK_KEX2_1	301	303	PF00082	0.710
CLV_PCSK_KEX2_1	53	55	PF00082	0.522
CLV_PCSK_PC1ET2_1	241	243	PF00082	0.743
CLV_PCSK_PC1ET2_1	298	300	PF00082	0.693
CLV_PCSK_PC1ET2_1	53	55	PF00082	0.522
CLV_PCSK_SKI1_1	102	106	PF00082	0.618
CLV_PCSK_SKI1_1	214	218	PF00082	0.651
CLV_PCSK_SKI1_1	302	306	PF00082	0.711
CLV_PCSK_SKI1_1	77	81	PF00082	0.555
CLV_Separin_Metazoa	215	219	PF03568	0.506
DEG_APCC_DBOX_1	148	156	PF00400	0.513
DEG_APCC_DBOX_1	213	221	PF00400	0.690
DEG_APCC_DBOX_1	76	84	PF00400	0.429
DOC_ANK_TNKS_1	168	175	PF00023	0.440
DOC_CKS1_1	181	186	PF01111	0.715
DOC_CYCLIN_RxL_1	74	81	PF00134	0.452
DOC_MAPK_gen_1	102	112	PF00069	0.595
DOC_MAPK_gen_1	149	157	PF00069	0.494
DOC_MAPK_gen_1	298	308	PF00069	0.651
DOC_MAPK_MEF2A_6	105	114	PF00069	0.492
DOC_MAPK_MEF2A_6	299	308	PF00069	0.685
DOC_PP1_RVXF_1	130	136	PF00149	0.486
DOC_PP1_RVXF_1	216	223	PF00149	0.606
DOC_USP7_MATH_1	168	172	PF00917	0.675
DOC_USP7_UBL2_3	196	200	PF12436	0.507
DOC_WW_Pin1_4	119	124	PF00397	0.471
DOC_WW_Pin1_4	180	185	PF00397	0.712
DOC_WW_Pin1_4	202	207	PF00397	0.674
DOC_WW_Pin1_4	272	277	PF00397	0.785
DOC_WW_Pin1_4	292	297	PF00397	0.553
DOC_WW_Pin1_4	308	313	PF00397	0.699
DOC_WW_Pin1_4	4	9	PF00397	0.609
LIG_14-3-3_CanoR_1	100	107	PF00244	0.600
LIG_14-3-3_CanoR_1	118	122	PF00244	0.296
LIG_14-3-3_CanoR_1	301	307	PF00244	0.699
LIG_Actin_WH2_2	103	120	PF00022	0.586
LIG_BIR_II_1	1	5	PF00653	0.560
LIG_FHA_1	120	126	PF00498	0.416
LIG_FHA_1	21	27	PF00498	0.592
LIG_FHA_1	281	287	PF00498	0.737
LIG_FHA_1	303	309	PF00498	0.811
LIG_FHA_1	56	62	PF00498	0.582
LIG_FHA_1	73	79	PF00498	0.342
LIG_FHA_2	142	148	PF00498	0.583
LIG_FHA_2	183	189	PF00498	0.734
LIG_FHA_2	255	261	PF00498	0.709
LIG_FHA_2	275	281	PF00498	0.611
LIG_FHA_2	83	89	PF00498	0.432
LIG_Integrin_RGD_1	244	246	PF01839	0.485
LIG_NRBOX	85	91	PF00104	0.536
LIG_SH2_STAT5	237	240	PF00017	0.578
LIG_SH3_2	309	314	PF14604	0.704
LIG_SH3_3	107	113	PF00018	0.440
LIG_SH3_3	176	182	PF00018	0.803
LIG_SH3_3	204	210	PF00018	0.645
LIG_SH3_3	270	276	PF00018	0.803
LIG_SH3_3	303	309	PF00018	0.722
LIG_SUMO_SIM_par_1	289	295	PF11976	0.684
LIG_SUMO_SIM_par_1	81	88	PF11976	0.325
LIG_SxIP_EBH_1	227	240	PF03271	0.744
LIG_UBA3_1	290	298	PF00899	0.676
MOD_CDC14_SPxK_1	295	298	PF00782	0.676
MOD_CDC14_SPxK_1	311	314	PF00782	0.708
MOD_CDK_SPxK_1	292	298	PF00069	0.676
MOD_CDK_SPxK_1	308	314	PF00069	0.703
MOD_CDK_SPxxK_3	292	299	PF00069	0.678
MOD_CK1_1	141	147	PF00069	0.652
MOD_CK1_1	202	208	PF00069	0.644
MOD_CK1_1	253	259	PF00069	0.810
MOD_CK1_1	68	74	PF00069	0.629
MOD_CK2_1	133	139	PF00069	0.495
MOD_CK2_1	141	147	PF00069	0.487
MOD_CK2_1	182	188	PF00069	0.727
MOD_CK2_1	192	198	PF00069	0.692
MOD_CK2_1	254	260	PF00069	0.630
MOD_CK2_1	82	88	PF00069	0.431
MOD_GlcNHglycan	139	143	PF01048	0.656
MOD_GlcNHglycan	170	173	PF01048	0.672
MOD_GlcNHglycan	231	234	PF01048	0.649
MOD_GlcNHglycan	269	272	PF01048	0.789
MOD_GlcNHglycan	27	30	PF01048	0.551
MOD_GlcNHglycan	65	68	PF01048	0.665
MOD_GlcNHglycan	91	94	PF01048	0.456
MOD_GSK3_1	117	124	PF00069	0.585
MOD_GSK3_1	229	236	PF00069	0.657
MOD_GSK3_1	250	257	PF00069	0.799
MOD_GSK3_1	272	279	PF00069	0.709
MOD_GSK3_1	68	75	PF00069	0.615
MOD_LATS_1	300	306	PF00433	0.520
MOD_N-GLC_1	302	307	PF02516	0.737
MOD_N-GLC_1	71	76	PF02516	0.534
MOD_NEK2_1	116	121	PF00069	0.479
MOD_NEK2_1	138	143	PF00069	0.644
MOD_NEK2_1	167	172	PF00069	0.609
MOD_NEK2_1	254	259	PF00069	0.592
MOD_NEK2_1	89	94	PF00069	0.449
MOD_PIKK_1	55	61	PF00454	0.511
MOD_PKA_2	117	123	PF00069	0.581
MOD_PKA_2	168	174	PF00069	0.724
MOD_PKB_1	98	106	PF00069	0.609
MOD_Plk_1	218	224	PF00069	0.652
MOD_Plk_1	302	308	PF00069	0.812
MOD_Plk_2-3	22	28	PF00069	0.552
MOD_Plk_4	121	127	PF00069	0.566
MOD_Plk_4	233	239	PF00069	0.602
MOD_ProDKin_1	119	125	PF00069	0.469
MOD_ProDKin_1	180	186	PF00069	0.711
MOD_ProDKin_1	202	208	PF00069	0.674
MOD_ProDKin_1	272	278	PF00069	0.787
MOD_ProDKin_1	292	298	PF00069	0.555
MOD_ProDKin_1	308	314	PF00069	0.703
MOD_ProDKin_1	4	10	PF00069	0.607
MOD_SUMO_rev_2	195	202	PF00179	0.798
TRG_DiLeu_BaEn_1	57	62	PF01217	0.591
TRG_DiLeu_BaLyEn_6	74	79	PF01217	0.457
TRG_ER_diArg_1	242	244	PF00400	0.674
TRG_ER_diArg_1	299	302	PF00400	0.700
TRG_NLS_Bipartite_1	227	245	PF00514	0.751
TRG_NLS_MonoCore_2	240	245	PF00514	0.768
TRG_NLS_MonoExtC_3	240	246	PF00514	0.772
TRG_NLS_MonoExtC_3	297	302	PF00514	0.693
TRG_NLS_MonoExtN_4	296	302	PF00514	0.691
TRG_Pf-PMV_PEXEL_1	289	294	PF00026	0.702
TRG_Pf-PMV_PEXEL_1	302	307	PF00026	0.572
TRG_Pf-PMV_PEXEL_1	77	81	PF00026	0.437

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZD5	Leptomonas seymouri	40%	100%
A0A3S7WPQ1	Leishmania donovani	86%	100%
A4H4U7	Leishmania braziliensis	74%	99%
A4HT26	Leishmania infantum	87%	100%
Q4QIU0	Leishmania major	88%	99%